Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for pax10+pax6a+pax6b

Z-value: 0.60

Motif logo

Transcription factors associated with pax10+pax6a+pax6b

Gene Symbol Gene ID Gene Info
ENSDARG00000045936 paired box 6b
ENSDARG00000053364 paired box 10
ENSDARG00000103379 paired box 6a
ENSDARG00000111379 paired box 10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax6bdr11_v1_chr7_+_15871156_15871156-0.972.0e-05Click!
pax6adr11_v1_chr25_-_15049694_15049781-0.791.2e-02Click!
pax10dr11_v1_chr3_+_32553714_32553714-0.608.6e-02Click!

Activity profile of pax10+pax6a+pax6b motif

Sorted Z-values of pax10+pax6a+pax6b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_2322102 1.43 ENSDART00000162867
zgc:66483
chr8_+_52442622 1.40 ENSDART00000012758
zgc:77112
chr25_+_22320738 1.33 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr5_+_57924611 1.23 ENSDART00000050949
B-cell translocation gene 4
chr18_+_14277003 1.16 ENSDART00000006628
zgc:173742
chr2_+_6255434 1.10 ENSDART00000139429
zona pellucida glycoprotein 3b
chr12_-_35582683 0.91 ENSDART00000167933
SEC24 homolog C, COPII coat complex component
chr8_+_52442785 0.90 ENSDART00000189958
zgc:77112
chr23_+_17926279 0.89 ENSDART00000012540
chitinase, acidic.4
chr21_-_22117085 0.81 ENSDART00000146673
solute carrier family 35, member F2
chr8_+_41038141 0.80 ENSDART00000075620
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr11_-_40257225 0.80 ENSDART00000139009
si:ch211-193i15.2
chr24_+_26379441 0.78 ENSDART00000137786
si:ch211-230g15.5
chr16_+_39159752 0.77 ENSDART00000122081
syntabulin (syntaxin-interacting)
chr9_-_2936017 0.74 ENSDART00000102823
sterile alpha motif and leucine zipper containing kinase AZK
chr10_-_8046764 0.69 ENSDART00000099031
zgc:136254
chr8_+_41037541 0.69 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr10_-_8053385 0.68 ENSDART00000142714
si:ch211-251f6.7
chr12_+_47794089 0.67 ENSDART00000160726
polymerase (RNA) III (DNA directed) polypeptide A
chr13_-_32726178 0.66 ENSDART00000012232
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr7_-_45852270 0.66 ENSDART00000170224
SHC SH2-domain binding protein 1
chr5_+_40837539 0.65 ENSDART00000188279
si:dkey-3h3.3
chr7_-_20582842 0.65 ENSDART00000169750
ENSDART00000111719
si:dkey-19b23.11
chr24_+_40905100 0.64 ENSDART00000167854
sodium channel, voltage gated, type XII, alpha b
chr5_-_26247973 0.64 ENSDART00000098527
endoplasmic reticulum aminopeptidase 1b
chr3_+_43086548 0.64 ENSDART00000163579
si:dkey-43p13.5
chr21_-_3700334 0.63 ENSDART00000137844
ATPase phospholipid transporting 8B1
chr23_-_40194732 0.63 ENSDART00000164931
transglutaminase 1 like 2
chr18_+_36782930 0.62 ENSDART00000004129
si:ch211-160d20.3
chr5_+_1109098 0.58 ENSDART00000166268

chr19_-_4793263 0.57 ENSDART00000147510
ENSDART00000141336
ENSDART00000110551
ENSDART00000146684
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr14_-_14659023 0.57 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr10_-_8053753 0.56 ENSDART00000162289
si:ch211-251f6.7
chr16_+_11779534 0.55 ENSDART00000133497
si:dkey-250k15.4
chr12_-_35582521 0.53 ENSDART00000162175
ENSDART00000168958
SEC24 homolog C, COPII coat complex component
chr1_-_29653472 0.52 ENSDART00000109224
si:dkey-1h24.2
chr24_-_2381143 0.52 ENSDART00000144307
ras responsive element binding protein 1a
chr9_+_8365398 0.52 ENSDART00000138713
ENSDART00000136847
si:dkey-90l23.2
chr2_+_25657958 0.52 ENSDART00000161407
TRAF2 and NCK interacting kinase a
chr25_+_19870603 0.52 ENSDART00000047251
GRAM domain containing 4b
chr13_-_4018888 0.51 ENSDART00000058238
tight junction associated protein 1 (peripheral)
chr11_-_8126223 0.50 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr16_+_11779761 0.49 ENSDART00000140297
si:dkey-250k15.4
chr3_-_34717882 0.49 ENSDART00000151127
thyroid hormone receptor alpha a
chr7_-_8738827 0.49 ENSDART00000172807
ENSDART00000173026
si:ch211-1o7.3
chr3_+_17346502 0.48 ENSDART00000187786
ENSDART00000131584
si:ch211-210g13.5
chr6_+_33076839 0.47 ENSDART00000073755
ENSDART00000122242
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
chr7_-_41512999 0.46 ENSDART00000173577
si:dkey-10f23.2
chr23_-_24542156 0.46 ENSDART00000132265
ATPase 13A2
chr5_-_69523816 0.46 ENSDART00000112692
si:ch211-157p22.10
chr4_-_13613148 0.45 ENSDART00000067164
ENSDART00000111247
interferon regulatory factor 5
chr3_-_54607166 0.44 ENSDART00000021977
DNA (cytosine-5-)-methyltransferase 1
chr15_-_1001177 0.44 ENSDART00000160730
zgc:162936
chr7_-_30624435 0.44 ENSDART00000173828
ring finger protein 111
chr5_-_33039670 0.43 ENSDART00000141361
GLI pathogenesis-related 2
chr14_-_45967981 0.43 ENSDART00000188062
MACRO domain containing 1
chr7_-_1101071 0.42 ENSDART00000176053
dynactin 1a
chr10_-_14920989 0.42 ENSDART00000184617
SMAD family member 2
chr5_+_41477954 0.41 ENSDART00000185871
protein inhibitor of activated STAT, 2
chr20_-_47348116 0.41 ENSDART00000162087
ENSDART00000160769
ENSDART00000164484
dystrobrevin, beta a
chr23_+_38957738 0.40 ENSDART00000193480
ATPase phospholipid transporting 9A (putative)
chr15_+_39977461 0.40 ENSDART00000063786
calcium binding protein 39
chr10_+_20392083 0.40 ENSDART00000166867
R3H domain and coiled-coil containing 1
chr5_+_32141790 0.40 ENSDART00000041504
tescalcin b
chr2_+_46032678 0.40 ENSDART00000184382
ENSDART00000125971
glypican 1b
chr9_-_53537989 0.39 ENSDART00000114022
SLIT and NTRK-like family, member 5b
chr5_-_47975440 0.39 ENSDART00000145665
ENSDART00000007057
cyclin H
chr17_+_43926523 0.39 ENSDART00000121550
ENSDART00000041447
kinectin 1
chr10_-_19497914 0.39 ENSDART00000132084
si:ch211-127i16.2
chr3_+_25914064 0.39 ENSDART00000162558
ENSDART00000166843
target of myb1 membrane trafficking protein
chr23_-_27505825 0.38 ENSDART00000137229
ENSDART00000013797
ankyrin repeat and SOCS box containing 8
chr16_+_48460873 0.38 ENSDART00000159902
exostosin glycosyltransferase 1a
chr5_-_28016805 0.38 ENSDART00000078642
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr15_-_43238220 0.38 ENSDART00000027019
WD repeat and FYVE domain containing 1
chr21_-_32781612 0.38 ENSDART00000031028
CCR4-NOT transcription complex, subunit 6a
chr20_+_51833030 0.38 ENSDART00000074330
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr17_-_15029258 0.37 ENSDART00000168332
ENSDART00000012877
ENSDART00000109190
endoplasmic reticulum oxidoreductase alpha
chr20_+_4222357 0.37 ENSDART00000188331
interaction protein for cytohesin exchange factors 1
chr15_-_25319663 0.37 ENSDART00000042218
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a
chr20_-_3238110 0.37 ENSDART00000008077
serine peptidase inhibitor, Kunitz type 1 b
chr7_+_26545502 0.37 ENSDART00000140528
tyrosine kinase, non-receptor, 1
chr3_-_8542577 0.37 ENSDART00000183527
RNA binding fox-1 homolog 3b
chr18_-_20466061 0.37 ENSDART00000060311
progestin and adipoQ receptor family member Va
chr14_-_30918662 0.37 ENSDART00000176631
si:ch211-126c2.4
chr11_-_44931962 0.36 ENSDART00000170345
phosphofructokinase, liver b
chr23_-_15916316 0.36 ENSDART00000134096
ENSDART00000042469
ENSDART00000146605
MRG/MORF4L binding protein
chr8_-_8489886 0.36 ENSDART00000183334
activator of basal transcription 1
chr14_+_31529958 0.36 ENSDART00000053026
family with sequence similarity 122B
chr4_-_5370468 0.36 ENSDART00000133423
ENSDART00000184963
si:dkey-14d8.1
chr8_-_43456025 0.36 ENSDART00000001092
ENSDART00000140618
nuclear receptor corepressor 2
chr17_-_41798856 0.36 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr16_+_21918503 0.36 ENSDART00000167919
zinc finger protein 687a
chr7_+_26545911 0.36 ENSDART00000135313
tyrosine kinase, non-receptor, 1
chr23_+_38957472 0.35 ENSDART00000193836
ATPase phospholipid transporting 9A (putative)
chr4_+_76466751 0.35 ENSDART00000164709
zgc:153116
chr3_-_26184018 0.34 ENSDART00000191604
si:ch211-11k18.4
chr9_-_746317 0.34 ENSDART00000129632
ENSDART00000130720
ubiquitin specific peptidase 37
chr25_+_7532811 0.34 ENSDART00000161593
phosphatidylserine synthase 2
chr12_-_3077395 0.34 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_-_58244220 0.34 ENSDART00000180450
un-named hu7910
chr19_-_15192840 0.33 ENSDART00000151337
phosphatase and actin regulator 4a
chr6_+_27923054 0.33 ENSDART00000136833
ENSDART00000145533
centrosomal protein 63
chr17_+_17804752 0.33 ENSDART00000123350
serine palmitoyltransferase, long chain base subunit 2a
chr7_+_24729558 0.33 ENSDART00000111542
ENSDART00000170100
shroom family member 4
chr20_+_27712714 0.33 ENSDART00000008306
zinc finger and BTB domain containing 1
chr5_-_55914268 0.33 ENSDART00000014049
WD repeat domain 36
chr19_-_25114701 0.33 ENSDART00000149035
protein tyrosine phosphatase type IVA, member 3
chr8_-_8489685 0.33 ENSDART00000131849
ENSDART00000064113
activator of basal transcription 1
chr3_-_36152974 0.32 ENSDART00000002568
endo-beta-N-acetylglucosaminidase
chr19_-_42503143 0.32 ENSDART00000007642
zgc:110239
chr18_-_45761868 0.32 ENSDART00000025423
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr9_-_31915423 0.32 ENSDART00000060051
fibroblast growth factor 14
chr19_+_34311374 0.32 ENSDART00000086617
gamma-aminobutyric acid (GABA) B receptor, 2
chr11_-_11336986 0.32 ENSDART00000016677
zgc:77929
chr16_+_13993285 0.32 ENSDART00000139130
ENSDART00000130353
si:dkey-85k15.7
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr12_+_23812530 0.32 ENSDART00000066331
supervillin a
chr15_+_19990068 0.31 ENSDART00000154033
ENSDART00000054428
zgc:112083
chr5_-_69316142 0.31 ENSDART00000157238
ENSDART00000144570
smoothelin b
chr8_-_28357177 0.31 ENSDART00000182319
kelch like family member 12
chr24_-_1010467 0.31 ENSDART00000114544
cyclin-dependent kinase 13
chr11_-_4023940 0.30 ENSDART00000058728
ENSDART00000171245
NIMA-related kinase 4
chr9_-_50000144 0.30 ENSDART00000123416
sodium channel, voltage-gated, type I, alpha
chr11_+_2902592 0.30 ENSDART00000093108
kinesin family member 21B
chr13_-_31164749 0.30 ENSDART00000049180
mitogen-activated protein kinase 8a
chr25_-_37284370 0.30 ENSDART00000103222
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr4_+_5341592 0.29 ENSDART00000123375
ENSDART00000067371
zgc:113263
chr18_-_16315822 0.29 ENSDART00000136479
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr1_+_2431956 0.29 ENSDART00000183832
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr22_+_18389271 0.29 ENSDART00000088270
YjeF N-terminal domain containing 3
chr4_-_9196291 0.29 ENSDART00000153963
host cell factor C2
chr22_-_35063526 0.29 ENSDART00000162211
zgc:63733
chr7_+_48555626 0.28 ENSDART00000125483
ENSDART00000083514
potassium voltage-gated channel, KQT-like subfamily, member 1
chr2_+_11031360 0.28 ENSDART00000180020
ENSDART00000145093
acyl-CoA thioesterase 11a
chr10_-_31015535 0.28 ENSDART00000146116
pannexin 3
chr22_+_21398508 0.27 ENSDART00000089408
ENSDART00000186091
Src homology 2 domain containing transforming protein D, b
chr16_-_25680666 0.27 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr13_-_25196758 0.26 ENSDART00000184722
adenosine kinase a
chr1_+_45839927 0.26 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
mitogen-activated protein kinase kinase 7
chr6_-_10034145 0.26 ENSDART00000185999
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr5_+_62374092 0.26 ENSDART00000082965

chr7_+_24496894 0.26 ENSDART00000149994
negative elongation factor complex member A
chr9_+_7732714 0.25 ENSDART00000145853
si:ch1073-349o24.2
chr15_+_1534644 0.25 ENSDART00000130413
structural maintenance of chromosomes 4
chr1_-_26045560 0.25 ENSDART00000172737
ENSDART00000076120
ENSDART00000193593
G patch domain and ankyrin repeats 1
chr10_+_20180163 0.24 ENSDART00000080016
protein phosphatase 3, catalytic subunit, gamma isozyme, b
chr25_+_5015019 0.24 ENSDART00000127600
histone deacetylase 10
chr22_+_8365905 0.24 ENSDART00000105945
si:dkey-19a16.11
chr22_+_22438783 0.24 ENSDART00000147825
kinesin family member 14
chr12_-_48374728 0.24 ENSDART00000153403
ENSDART00000188117
DnaJ (Hsp40) homolog, subfamily B, member 12b
chr24_+_28383278 0.24 ENSDART00000018095
SH3-domain GRB2-like endophilin B1a
chr5_-_38438613 0.24 ENSDART00000131912
phospholipase D2
chr13_-_31167461 0.23 ENSDART00000190640
ENSDART00000192002
mitogen-activated protein kinase 8a
chr1_+_26105141 0.23 ENSDART00000102379
ENSDART00000127154
topoisomerase I binding, arginine/serine-rich a
chr19_+_32201991 0.23 ENSDART00000022667
family with sequence similarity 8, member A1a
chr14_-_5407555 0.23 ENSDART00000001424
polycomb group ring finger 1
chr18_-_42313798 0.23 ENSDART00000098639
contactin 5
chr25_+_25516016 0.23 ENSDART00000188980
PHD and ring finger domains 1
chr7_-_19526721 0.23 ENSDART00000114203
mannosidase, alpha, class 2B, member 2
chr25_-_8201983 0.23 ENSDART00000006579
serum amyloid A-like 1
chr8_+_25892319 0.23 ENSDART00000187167
ENSDART00000078163
transmembrane protein 115
chr3_+_60828813 0.22 ENSDART00000128260

chr23_-_18381361 0.22 ENSDART00000016891
hydroxysteroid (17-beta) dehydrogenase 10
chr23_-_33680265 0.22 ENSDART00000138416
transcription factor CP2
chr5_+_26807142 0.22 ENSDART00000188981
RAB, member RAS oncogene family-like 6b
chr5_-_26330313 0.22 ENSDART00000148656
ARVCF, delta catenin family member b
chr5_+_41477526 0.22 ENSDART00000153567
protein inhibitor of activated STAT, 2
chr13_+_23093743 0.22 ENSDART00000148034
phosphoinositide-3-kinase adaptor protein 1
chr13_-_48388726 0.22 ENSDART00000169473
F-box protein 11a
chr6_-_51811095 0.22 ENSDART00000161048
proteasome inhibitor subunit 1
chr7_+_48555400 0.21 ENSDART00000174474
potassium voltage-gated channel, KQT-like subfamily, member 1
chr11_-_45152702 0.21 ENSDART00000168066
arylformamidase
chr17_+_8799451 0.21 ENSDART00000189814
ENSDART00000191577
tonsoku-like, DNA repair protein
chr24_+_25032340 0.20 ENSDART00000005845
myotubularin related protein 6
chr5_+_26686279 0.20 ENSDART00000193543
transport and golgi organization 2 homolog (Drosophila)
chr12_+_33361948 0.20 ENSDART00000124982
fatty acid synthase
chr23_-_7125494 0.20 ENSDART00000111929
solute carrier organic anion transporter family, member 4A1
chr18_+_50924556 0.20 ENSDART00000159287
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr13_-_11378127 0.20 ENSDART00000158632
v-akt murine thymoma viral oncogene homolog 3a
chr7_-_17814118 0.20 ENSDART00000179688
ECSIT signalling integrator
chr21_-_1644414 0.20 ENSDART00000105736
ENSDART00000124904
zgc:152948
chr5_+_62052750 0.19 ENSDART00000192103
ENSDART00000181866
si:dkey-35m8.1
chr11_+_6115621 0.19 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nuclear receptor subfamily 2, group F, member 6b
chr10_+_37500234 0.19 ENSDART00000132096
ENSDART00000099473
musashi RNA-binding protein 2a
chr1_+_53714734 0.19 ENSDART00000114689
pseudouridylate synthase 10
chr18_-_17513426 0.19 ENSDART00000146725
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr24_-_36270855 0.19 ENSDART00000154858
si:ch211-40k21.5
chr8_+_26083808 0.18 ENSDART00000099283
DALR anticodon binding domain containing 3
chr15_-_704408 0.18 ENSDART00000156200
ENSDART00000166404
ENSDART00000131040
zgc:174574
chr18_+_3064237 0.18 ENSDART00000161848
integrator complex subunit 4
chr1_+_12068800 0.18 ENSDART00000055566
xeroderma pigmentosum, complementation group A
chr14_-_7375049 0.18 ENSDART00000054809
trafficking protein particle complex 11
chr19_-_20163197 0.18 ENSDART00000148179
ENSDART00000151646
family with sequence similarity 221, member A
chr5_-_19036164 0.18 ENSDART00000099378
family with sequence similarity 214, member B
chr2_-_43739559 0.18 ENSDART00000138947
kinesin family member 5B, a
chr23_+_30707837 0.18 ENSDART00000016096
DnaJ (Hsp40) homolog, subfamily C, member 11a
chr23_-_2901167 0.18 ENSDART00000165955
ENSDART00000190616
zinc fingers and homeoboxes 3
chr9_+_40546677 0.17 ENSDART00000132911
von Willebrand factor C domain containing protein 2-like
chr13_+_21919786 0.17 ENSDART00000182440
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2a
chr11_-_45152912 0.17 ENSDART00000167540
ENSDART00000173050
ENSDART00000170795
arylformamidase
chr17_+_8799661 0.17 ENSDART00000105326
tonsoku-like, DNA repair protein

Network of associatons between targets according to the STRING database.

First level regulatory network of pax10+pax6a+pax6b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 0.7 GO:0000480 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 1.5 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.2 0.8 GO:0060074 synapse maturation(GO:0060074)
0.1 0.5 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 2.3 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.9 GO:0006032 chitin catabolic process(GO:0006032)
0.1 0.3 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.2 GO:0006265 DNA topological change(GO:0006265)
0.1 0.3 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.1 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.2 GO:0070914 UV-damage excision repair(GO:0070914) nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 0.6 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.5 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.3 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.5 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.3 GO:0044209 AMP salvage(GO:0044209)
0.0 0.3 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.4 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0071548 response to dexamethasone(GO:0071548)
0.0 0.3 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.7 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0006203 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.3 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.7 GO:0016233 telomere capping(GO:0016233)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.1 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.3 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0036353 histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.6 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 1.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.4 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.2 GO:0060324 face development(GO:0060324)
0.0 0.4 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.2 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 1.1 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.4 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.7 GO:0070187 telosome(GO:0070187)
0.0 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.3 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.3 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 1.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 2.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 1.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 1.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.2 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.1 1.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.2 GO:0019894 kinesin binding(GO:0019894)
0.1 0.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.5 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.3 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 ST GA13 PATHWAY G alpha 13 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1