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PRJNA195909:zebrafish embryo and larva development

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Results for pou6f2

Z-value: 1.21

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Transcription factors associated with pou6f2

Gene Symbol Gene ID Gene Info
ENSDARG00000086362 POU class 6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou6f2dr11_v1_chr24_+_10202718_10202718-0.665.4e-02Click!

Activity profile of pou6f2 motif

Sorted Z-values of pou6f2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_17698517 3.41 ENSDART00000105974
parvalbumin 9
chr3_-_61162750 2.78 ENSDART00000055064
parvalbumin 8
chr18_-_1185772 2.77 ENSDART00000143245
neuroplastin b
chr12_-_35830625 2.75 ENSDART00000180028

chr12_-_17698669 2.66 ENSDART00000191384
parvalbumin 9
chr12_-_26406323 2.49 ENSDART00000131896
myozenin 1b
chr8_+_33035709 2.06 ENSDART00000131660
angiopoietin-like 2b
chr3_-_43356082 2.04 ENSDART00000171213
UNC homeobox
chr2_-_35566938 1.94 ENSDART00000029006
ENSDART00000077178
ENSDART00000125298
tenascin N
chr4_+_12615836 1.91 ENSDART00000003583
LIM domain only 3
chr2_-_44255537 1.89 ENSDART00000011188
ENSDART00000093298
ATPase Na+/K+ transporting subunit alpha 2
chr13_+_25449681 1.84 ENSDART00000101328
atonal bHLH transcription factor 7
chr20_-_48485354 1.81 ENSDART00000124040
ENSDART00000148437
insulinoma-associated 1a
chr3_-_46817499 1.73 ENSDART00000013717
ELAV like neuron-specific RNA binding protein 3
chr3_+_23737795 1.72 ENSDART00000182247
homeobox B3a
chr16_-_2414063 1.69 ENSDART00000073621
zgc:152945
chr16_-_31717851 1.64 ENSDART00000169109
retinol binding protein 1a, cellular
chr24_-_21923930 1.62 ENSDART00000131944
transgelin 3b
chr3_+_23738215 1.62 ENSDART00000143981
homeobox B3a
chr22_-_13350240 1.61 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
chr19_+_30662529 1.52 ENSDART00000175662
family with sequence similarity 49, member A-like
chr16_-_31718013 1.39 ENSDART00000190716
retinol binding protein 1a, cellular
chr13_-_31435137 1.38 ENSDART00000057441
reticulon 1a
chr24_+_9744012 1.37 ENSDART00000129656
transmembrane protein 108
chr4_-_16341801 1.36 ENSDART00000140190
keratocan
chr13_+_24662238 1.36 ENSDART00000014176
muscle segment homeobox 3
chr12_+_20352400 1.31 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr4_-_17629444 1.25 ENSDART00000108814
nuclear receptor interacting protein 2
chr11_+_41981959 1.24 ENSDART00000055707
hairy and enhancer of split-related 15, tandem duplicate 1
chr13_+_35339182 1.23 ENSDART00000019323
jagged 1b
chr16_+_46111849 1.20 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr20_+_4060839 1.19 ENSDART00000178565
tripartite motif containing 67
chr1_+_25696798 1.18 ENSDART00000054228
lecithin retinol acyltransferase a
chr9_-_14504834 1.15 ENSDART00000056103
neuropilin 2b
chr22_-_13042992 1.15 ENSDART00000028787
aryl hydrocarbon receptor 1b
chr19_-_32641725 1.08 ENSDART00000165006
ENSDART00000188185
hippocalcin
chr25_+_35553542 1.07 ENSDART00000113723
Spi-1 proto-oncogene a
chr3_+_33341640 1.06 ENSDART00000186352
peptide YYa
chr1_+_40023640 1.05 ENSDART00000101623
leucine-rich repeat LGI family, member 2b
chr17_-_49977966 1.04 ENSDART00000183735
collagen, type XII, alpha 1a
chr19_-_31402429 1.03 ENSDART00000137292
transmembrane protein 106Bb
chr25_+_6186823 0.98 ENSDART00000153526
ornithine decarboxylase antizyme 2a
chr3_-_28250722 0.97 ENSDART00000165936
RNA binding fox-1 homolog 1
chr20_-_9436521 0.95 ENSDART00000133000
zgc:101840
chr4_+_12612145 0.94 ENSDART00000181201
LIM domain only 3
chr23_+_28731379 0.92 ENSDART00000047378
cortistatin
chr2_-_50372467 0.92 ENSDART00000108900
contactin associated protein like 2b
chr23_+_31107685 0.90 ENSDART00000103448
T-box 18
chr12_-_10275320 0.87 ENSDART00000170078
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr15_-_17870090 0.83 ENSDART00000155066
activating transcription factor 5b
chr16_-_29702447 0.83 ENSDART00000150617
tumor necrosis factor, alpha-induced protein 8-like 2b
chr6_+_4033832 0.82 ENSDART00000159952
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb
chr4_+_22365061 0.80 ENSDART00000039277
LHFPL tetraspan subfamily member 3
chr1_+_50968908 0.78 ENSDART00000150353
ENSDART00000012842
malate dehydrogenase 1Aa, NAD (soluble)
chr22_-_30881738 0.77 ENSDART00000059965
si:dkey-49n23.1
chr8_-_23776399 0.77 ENSDART00000114800
si:ch211-163l21.4
chr11_+_20057182 0.77 ENSDART00000184979
FEZ family zinc finger 2
chr5_-_48268049 0.76 ENSDART00000187454
myocyte enhancer factor 2cb
chr9_-_32753535 0.76 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr13_+_22476742 0.76 ENSDART00000078759
ENSDART00000130101
ENSDART00000137220
ENSDART00000133065
ENSDART00000147348
LIM domain binding 3a
chr7_-_31759602 0.75 ENSDART00000113467
immunoglobulin superfamily, DCC subclass, member 4
chr10_-_24391716 0.75 ENSDART00000141332
ENSDART00000100772
solute carrier family 43 (amino acid system L transporter), member 2b
chr13_-_42560662 0.74 ENSDART00000124898

chr3_-_21288202 0.74 ENSDART00000191766
ENSDART00000187319
family with sequence similarity 171, member A2a
chr7_+_58699900 0.74 ENSDART00000144009
short chain dehydrogenase/reductase family 16C, member 5b
chr7_-_27686021 0.73 ENSDART00000079112
ENSDART00000100989
calcitonin/calcitonin-related polypeptide, alpha
chr21_+_25231160 0.73 ENSDART00000063089
ENSDART00000139127
guanine nucleotide binding protein (G protein), gamma 8
chr17_-_37052622 0.72 ENSDART00000186408
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr3_+_57038033 0.72 ENSDART00000162930
BAH domain and coiled-coil containing 1a
chr6_+_27146671 0.72 ENSDART00000156792
kinesin family member 1Aa
chr13_+_30912117 0.70 ENSDART00000133138
dorsal root ganglia homeobox
chr15_+_7057050 0.70 ENSDART00000061828
forkhead box L2a
chr6_+_3004972 0.70 ENSDART00000186750
ENSDART00000183862
ENSDART00000191485
ENSDART00000171014
protein tyrosine phosphatase, receptor type, f, a
chr6_+_16406723 0.69 ENSDART00000040035
coiled-coil domain containing 80 like 1
chr17_-_48705993 0.68 ENSDART00000030934
potassium channel, subfamily K, member 5a
chr16_-_12173554 0.66 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr17_-_24916889 0.66 ENSDART00000156157
si:ch211-195o20.7
chr20_+_28245164 0.65 ENSDART00000103320
delta-like 4 (Drosophila)
chr1_+_25801648 0.65 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr11_+_38280454 0.64 ENSDART00000171496
si:dkey-166c18.1
chr11_-_45138857 0.64 ENSDART00000166501
calcium activated nucleotidase 1b
chr16_+_43152727 0.64 ENSDART00000125590
ENSDART00000154493
ADAM metallopeptidase domain 22
chr12_+_35654749 0.64 ENSDART00000169889
ENSDART00000167873
BAI1-associated protein 2b
chr4_+_72723304 0.64 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
RAB3A interacting protein (rabin3)
chr19_-_26869103 0.63 ENSDART00000089699
proline-rich transmembrane protein 1
chr20_-_22476255 0.63 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr7_-_30174882 0.62 ENSDART00000110409
FERM domain containing 5
chr21_-_26918901 0.62 ENSDART00000100685
leucine rich repeat and fibronectin type III domain containing 4a
chr17_+_11675362 0.61 ENSDART00000157911
kinesin family member 26Ba
chr9_-_38036984 0.61 ENSDART00000134574
3-hydroxyacyl-CoA dehydratase 2
chr11_+_20056732 0.60 ENSDART00000103997
FEZ family zinc finger 2
chr10_-_27199135 0.60 ENSDART00000189511
ENSDART00000180314
autism susceptibility candidate 2a
chr5_-_23362602 0.58 ENSDART00000137120
glutamate receptor, ionotropic, AMPA 3a
chr11_-_42918971 0.58 ENSDART00000052912
protocadherin 20
chr7_-_27685365 0.57 ENSDART00000188342
calcitonin/calcitonin-related polypeptide, alpha
chr3_-_56541723 0.57 ENSDART00000156398
ENSDART00000050576
ENSDART00000184874
si:ch211-189a21.1
cytohesin 1a
chr8_+_21588067 0.57 ENSDART00000172190
adherens junctions associated protein 1
chr23_+_41912151 0.55 ENSDART00000191115
podocan
chr7_-_22941472 0.53 ENSDART00000190334
TNF superfamily member 10, like
chr4_+_12612723 0.53 ENSDART00000133767
LIM domain only 3
chr10_-_26738209 0.53 ENSDART00000188590
fibroblast growth factor 13b
chr20_+_28245587 0.52 ENSDART00000191703
delta-like 4 (Drosophila)
chr25_+_13498188 0.51 ENSDART00000015710
SNF related kinase b
chr15_+_21276735 0.49 ENSDART00000111213
ubiquitin associated and SH3 domain containing Bb
chr13_+_1089942 0.48 ENSDART00000054322
cannabinoid receptor interacting protein 1b
chr22_+_9472814 0.47 ENSDART00000112125
ENSDART00000138850
calcium channel, voltage-dependent, alpha 2/delta subunit 2b
chr7_-_31759394 0.47 ENSDART00000193040
immunoglobulin superfamily, DCC subclass, member 4
chr13_+_16279890 0.47 ENSDART00000101775
ENSDART00000057948
annexin A11a
chr25_+_32755485 0.47 ENSDART00000162188
electron-transfer-flavoprotein, alpha polypeptide
chr7_-_39203799 0.47 ENSDART00000173727
cholinergic receptor, muscarinic 4a
chr9_-_40765868 0.46 ENSDART00000138634
ATP-binding cassette, sub-family A (ABC1), member 12
chr21_-_20733615 0.46 ENSDART00000145544
si:ch211-22d5.2
chr15_-_14469704 0.44 ENSDART00000185077
numb homolog (Drosophila)-like
chr11_-_27702778 0.44 ENSDART00000045942
ENSDART00000125352
PHD finger protein 2
chr17_-_29902187 0.43 ENSDART00000009104
estrogen-related receptor beta
chr16_-_12173399 0.43 ENSDART00000142574
calsyntenin 3
chr15_+_5360407 0.42 ENSDART00000110420
odorant receptor, family A, subfamily 112, member 1
chr4_+_5642696 0.42 ENSDART00000028941
mitochondrial ribosomal protein S18A
chr8_+_37755099 0.42 ENSDART00000075708
ENSDART00000140966
glutamic-oxaloacetic transaminase 1 like 1
chr4_+_3980247 0.42 ENSDART00000049194
G protein-coupled receptor 37b
chr23_-_28141419 0.42 ENSDART00000133039
tachykinin 3a
chr24_-_39186185 0.42 ENSDART00000123019
ENSDART00000191114
nucleotide binding protein 2 (MinD homolog, E. coli)
chr3_-_58798377 0.42 ENSDART00000161248
si:ch73-281f12.4
chr6_-_40722480 0.41 ENSDART00000188187
kelch repeat and BTB (POZ) domain containing 12
chr21_-_37973819 0.41 ENSDART00000133405
ripply transcriptional repressor 1
chr15_-_13208607 0.40 ENSDART00000184151
zgc:172282
chr3_-_58798815 0.40 ENSDART00000082920
si:ch73-281f12.4
chr6_-_39344259 0.40 ENSDART00000104074
zgc:158846
chr6_-_40722200 0.39 ENSDART00000035101
kelch repeat and BTB (POZ) domain containing 12
chr3_+_17537352 0.38 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr18_+_43365890 0.38 ENSDART00000173113
si:ch211-129p13.1
chr17_+_51499789 0.38 ENSDART00000187701

chr18_+_7283283 0.37 ENSDART00000141493
si:ch73-86n2.1
chr21_-_37790727 0.36 ENSDART00000162907
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr4_+_2619132 0.36 ENSDART00000128807
G protein-coupled receptor 22a
chr20_+_37294112 0.35 ENSDART00000076293
ENSDART00000140450
connexin 23
chr6_+_23712911 0.35 ENSDART00000167795
zgc:158654
chr13_-_45155792 0.34 ENSDART00000163556
runt-related transcription factor 3
chr1_-_55270966 0.34 ENSDART00000152807
si:ch211-286b5.5
chr21_+_40232910 0.33 ENSDART00000075915
odorant receptor, family F, subfamily 115, member 11
chr4_-_76370630 0.33 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
chr3_-_49110710 0.33 ENSDART00000160404
tripartite motif containing 35-12
chr19_-_657439 0.32 ENSDART00000167100
solute carrier family 6 (neutral amino acid transporter), member 18
chr10_-_9192450 0.32 ENSDART00000139783
si:dkeyp-41f9.4
chr8_+_51050554 0.32 ENSDART00000166249
si:dkey-32e23.6
chr23_+_21405201 0.31 ENSDART00000144409
intermediate filament family orphan 2a
chr1_-_9123465 0.31 ENSDART00000081337
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1a
chr13_+_18533005 0.31 ENSDART00000136024
finTRIM family, member 14-like
chr13_-_44630111 0.30 ENSDART00000110092
MAM domain containing glycosylphosphatidylinositol anchor 1
chr18_-_2433011 0.30 ENSDART00000181922
ENSDART00000193276

chr10_+_3507861 0.30 ENSDART00000092684
rabphilin 3A homolog (mouse), a
chr8_+_20776654 0.30 ENSDART00000135850
nuclear factor I/C
chr12_+_41697664 0.29 ENSDART00000162302
BCL2 interacting protein 3
chr20_-_48516765 0.27 ENSDART00000150200
si:zfos-223e1.2
chr14_+_41345175 0.27 ENSDART00000086104
NADPH oxidase 1
chr18_-_40773413 0.26 ENSDART00000133797
vasodilator stimulated phosphoprotein b
chr7_+_36898850 0.26 ENSDART00000113342
TOX high mobility group box family member 3
chr10_-_34870667 0.26 ENSDART00000161272
doublecortin-like kinase 1a
chr12_+_28117365 0.25 ENSDART00000066290
urotensin 2 receptor
chr24_+_40473032 0.25 ENSDART00000084238
ENSDART00000178508

chr16_+_42481447 0.25 ENSDART00000037401
HERPUD family member 2
chr2_-_17044959 0.22 ENSDART00000090260
chloride channel, voltage-sensitive 2a
chr1_-_57501299 0.22 ENSDART00000080600
zgc:171470
chr7_+_41303572 0.21 ENSDART00000012692
regulator of G protein signaling 9 binding protein
chr2_-_10906854 0.21 ENSDART00000150227
CUB domain containing protein 2
chr14_+_45471642 0.20 ENSDART00000126979
ENSDART00000172952
ENSDART00000173284
UBX domain protein 1
chr15_-_38154616 0.20 ENSDART00000099392
immunity-related GTPase family, q2
chr11_+_33284837 0.20 ENSDART00000166239
ENSDART00000111412
NTPase, KAP family P-loop domain containing 1
chr5_-_30481263 0.19 ENSDART00000086734
pleckstrin homology-like domain, family B, member 1a
chr7_-_4315859 0.19 ENSDART00000172762
si:ch211-63p21.8
chr17_-_45150763 0.19 ENSDART00000155043
ENSDART00000156786
ENSDART00000191147
transmembrane p24 trafficking protein 8
chr22_+_25814941 0.19 ENSDART00000161120
vasorin a
chr5_+_21211135 0.18 ENSDART00000088492
bone morphogenetic protein 10
chr20_-_40755614 0.18 ENSDART00000061247
connexin 32.3
chr24_-_28648949 0.18 ENSDART00000180227
trans-2,3-enoyl-CoA reductase-like 2a
chr18_-_8398972 0.18 ENSDART00000136512
si:ch211-220f12.4
chr9_-_44953664 0.17 ENSDART00000188558
ENSDART00000185210
villin 1
chr8_+_8927870 0.17 ENSDART00000081985
Pim-2 proto-oncogene, serine/threonine kinase
chr9_-_19699728 0.17 ENSDART00000166780
si:ch211-141e20.2
chr9_-_6624663 0.16 ENSDART00000092537
si:dkeyp-118h3.5
chr11_+_24620742 0.16 ENSDART00000182471
ENSDART00000048365
synaptotagmin VIb
chr24_-_21404367 0.16 ENSDART00000152093
ATPase phospholipid transporting 8A2
chr18_+_34362608 0.15 ENSDART00000131478
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr5_-_50641129 0.15 ENSDART00000190090
multiple C2 domains, transmembrane 1a
chr5_-_26566435 0.15 ENSDART00000146070
ARVCF, delta catenin family member b
chr2_+_39021282 0.15 ENSDART00000056577
si:ch211-119o8.7
chr11_-_37425407 0.15 ENSDART00000160911
ELKS/RAB6-interacting/CAST family member 2
chr2_+_29249204 0.14 ENSDART00000168957
cadherin 18, type 2a
chr13_-_3370638 0.14 ENSDART00000029649
parkin RBR E3 ubiquitin protein ligase
chr16_+_16849220 0.13 ENSDART00000047409
ENSDART00000142155
myosin, heavy chain 14, non-muscle
chr14_+_23717165 0.12 ENSDART00000006373
Nedd4 family interacting protein 1
chr23_+_6077503 0.12 ENSDART00000081714
ENSDART00000139834
myosin binding protein Ha
chr5_-_35953472 0.12 ENSDART00000143448
relaxin/insulin-like family peptide receptor 2, like
chr10_+_19528321 0.12 ENSDART00000184816
V-set and immunoglobulin domain containing 8a
chr18_-_43993614 0.11 ENSDART00000148535
ENSDART00000077357
B cell CLL/lymphoma 9-like
chr16_+_26012569 0.11 ENSDART00000148846
protease, serine, 59, tandem duplicate 1
chr8_+_6576940 0.11 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr18_+_14529005 0.10 ENSDART00000186379
potassium voltage-gated channel, subfamily G, member 4a
chr22_+_2830703 0.10 ENSDART00000145463
ENSDART00000144785
si:dkey-20i20.8
chr12_-_28983584 0.09 ENSDART00000112374
zgc:171713

Network of associatons between targets according to the STRING database.

First level regulatory network of pou6f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0065001 specification of axis polarity(GO:0065001)
0.4 1.2 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.3 1.8 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.2 0.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 1.4 GO:0021767 mammillary body development(GO:0021767)
0.2 0.8 GO:0021742 abducens nucleus development(GO:0021742)
0.2 0.9 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 1.4 GO:0097106 postsynaptic density organization(GO:0097106)
0.2 0.6 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 0.8 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.4 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.6 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 2.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.4 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 1.2 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 0.4 GO:0042755 eating behavior(GO:0042755)
0.1 2.8 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.2 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 1.3 GO:0015671 oxygen transport(GO:0015671)
0.1 0.2 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 1.0 GO:0032418 lysosome localization(GO:0032418)
0.1 1.0 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 0.5 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.5 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 0.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.5 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 1.1 GO:0002761 regulation of myeloid leukocyte differentiation(GO:0002761)
0.0 1.1 GO:0007631 feeding behavior(GO:0007631)
0.0 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 1.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.0 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 1.4 GO:0043049 otic placode formation(GO:0043049)
0.0 1.8 GO:0036269 swimming behavior(GO:0036269)
0.0 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.0 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.6 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.6 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.8 GO:0060914 heart formation(GO:0060914)
0.0 1.1 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.0 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.0 0.5 GO:0032506 cytokinetic process(GO:0032506)
0.0 1.9 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 1.8 GO:0001756 somitogenesis(GO:0001756)
0.0 0.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.1 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0001843 neural tube closure(GO:0001843)
0.0 0.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.9 GO:0033010 paranodal junction(GO:0033010)
0.1 1.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.3 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 4.8 GO:0030424 axon(GO:0030424)
0.0 0.5 GO:0030426 growth cone(GO:0030426)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.4 1.2 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.3 3.0 GO:0016918 retinal binding(GO:0016918)
0.2 2.5 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 1.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.1 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.2 1.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 0.6 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.2 0.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 0.6 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 1.3 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0000035 acyl binding(GO:0000035)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 1.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 2.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.8 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 2.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters