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PRJNA195909:zebrafish embryo and larva development

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Results for scrt1a+scrt1b+scrt2

Z-value: 0.97

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Transcription factors associated with scrt1a+scrt1b+scrt2

Gene Symbol Gene ID Gene Info
scrt1b
ENSDARG00000040214 scratch family zinc finger 1b
scrt2
ENSDARG00000056175 scratch family zinc finger 2
scrt1a
ENSDARG00000100821 scratch family zinc finger 1a
scrt1b
ENSDARG00000110984 scratch family zinc finger 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
scrt2dr11_v1_chr8_+_28527776_285277760.637.1e-02Click!
scrt1adr11_v1_chr19_+_1184878_11848780.511.6e-01Click!
scrt1bdr11_v1_chr16_-_31188715_311887150.333.8e-01Click!

Activity profile of scrt1a+scrt1b+scrt2 motif

Sorted Z-values of scrt1a+scrt1b+scrt2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_32446406 1.77 ENSDART00000026635
nr2e1
nuclear receptor subfamily 2, group E, member 1
chr11_+_36477481 1.11 ENSDART00000128245
ldlrad2
low density lipoprotein receptor class A domain containing 2
chr10_+_9550419 1.09 ENSDART00000064977
si:ch211-243g18.2
si:ch211-243g18.2
chr15_+_5923851 0.95 ENSDART00000152520
ENSDART00000145827
ENSDART00000121529
sh3bgr
SH3 domain binding glutamate-rich protein
chr2_+_2470687 0.85 ENSDART00000184024
ENSDART00000061955
myl13
myosin, light chain 13
chr8_-_16259063 0.82 ENSDART00000057590
dmrta2
DMRT-like family A2
chr8_-_1051438 0.79 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr13_-_39159810 0.79 ENSDART00000131508
col9a1b
collagen, type IX, alpha 1b
chr3_+_59851537 0.77 ENSDART00000180997
CU693479.1

chr5_-_65782783 0.74 ENSDART00000130888
ENSDART00000050855
notch1b
notch 1b
chr9_-_34300707 0.72 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
chr16_+_5678071 0.72 ENSDART00000011166
ENSDART00000134198
ENSDART00000131575
zgc:158689
zgc:158689
chr16_-_45225520 0.70 ENSDART00000158855
fxyd1
FXYD domain containing ion transport regulator 1 (phospholemman)
chr3_-_12930217 0.69 ENSDART00000166322
pdgfab
platelet-derived growth factor alpha polypeptide b
chr20_+_40150612 0.68 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
trdn
triadin
chr1_+_7679328 0.66 ENSDART00000163488
ENSDART00000190070
en1b
engrailed homeobox 1b
chr25_+_14507567 0.64 ENSDART00000015681
dbx1b
developing brain homeobox 1b
chr15_-_41245962 0.64 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr23_-_6522099 0.63 ENSDART00000092214
ENSDART00000183380
ENSDART00000138020
bmp7b
bone morphogenetic protein 7b
chr23_+_36083529 0.56 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr20_+_34512130 0.55 ENSDART00000131637
prrx1b
paired related homeobox 1b
chr20_+_34511678 0.54 ENSDART00000061588
prrx1b
paired related homeobox 1b
chr8_+_31821396 0.48 ENSDART00000077053
plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr10_-_25860102 0.48 ENSDART00000080789
trpc4a
transient receptor potential cation channel, subfamily C, member 4a
chr3_+_37574885 0.46 ENSDART00000055225
wnt9b
wingless-type MMTV integration site family, member 9B
chr13_+_13578552 0.46 ENSDART00000101673
foxi2
forkhead box I2
chr18_+_38191346 0.42 ENSDART00000052703
nucb2b
nucleobindin 2b
chr2_-_6115688 0.41 ENSDART00000081663
prdx1
peroxiredoxin 1
chr3_+_16265924 0.38 ENSDART00000122519
st8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr21_+_41697552 0.36 ENSDART00000169511
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr2_-_6115389 0.36 ENSDART00000134921
prdx1
peroxiredoxin 1
chr2_+_10766744 0.35 ENSDART00000015379
gfi1aa
growth factor independent 1A transcription repressor a
chr7_-_38340674 0.34 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr15_+_36309070 0.34 ENSDART00000157034
gmnc
geminin coiled-coil domain containing
chr11_+_7261981 0.33 ENSDART00000130400
ENSDART00000155427
reep6
receptor accessory protein 6
chr10_-_1827225 0.31 ENSDART00000058627
epb41l4a
erythrocyte membrane protein band 4.1 like 4A
chr16_-_17072440 0.30 ENSDART00000002493
ENSDART00000178443
tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr3_-_30158395 0.29 ENSDART00000103502
si:ch211-152f23.5
si:ch211-152f23.5
chr2_+_2223837 0.29 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr3_-_56030117 0.28 ENSDART00000113030
ENSDART00000157764
cep112
centrosomal protein 112
chr22_-_23545307 0.28 ENSDART00000166915
crb1
crumbs family member 1, photoreceptor morphogenesis associated
chr17_-_5583345 0.27 ENSDART00000035944
clic5a
chloride intracellular channel 5a
chr24_+_25913162 0.27 ENSDART00000143099
ENSDART00000184814
map3k15
mitogen-activated protein kinase kinase kinase 15
chr1_+_53377432 0.27 ENSDART00000177581
ucp1
uncoupling protein 1
chr5_-_10768258 0.26 ENSDART00000157043
rtn4r
reticulon 4 receptor
chr7_+_38897836 0.26 ENSDART00000024330
creb3l1
cAMP responsive element binding protein 3-like 1
chr13_-_36844945 0.26 ENSDART00000129562
ENSDART00000150899
nin
ninein (GSK3B interacting protein)
chr4_+_2228754 0.25 ENSDART00000166058
cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr16_-_33930759 0.25 ENSDART00000177453
dnali1
dynein, axonemal, light intermediate chain 1
chr2_-_30659222 0.25 ENSDART00000145405
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr16_-_39570832 0.25 ENSDART00000039832
tgfbr2b
transforming growth factor beta receptor 2b
chr7_+_47287307 0.24 ENSDART00000114669
dpy19l3
dpy-19 like C-mannosyltransferase 3
chr4_+_16710001 0.23 ENSDART00000035899
pkp2
plakophilin 2
chr13_+_25486608 0.23 ENSDART00000057689
bag3
BCL2 associated athanogene 3
chr3_+_62126981 0.23 ENSDART00000060527
drc3
dynein regulatory complex subunit 3
chr20_+_22220988 0.23 ENSDART00000049204
kdr
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr12_-_28818720 0.23 ENSDART00000134453
ENSDART00000141727
prr15lb
proline rich 15-like b
chr14_+_6423973 0.22 ENSDART00000051556
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr9_-_21970067 0.22 ENSDART00000009920
lmo7a
LIM domain 7a
chr2_+_25378457 0.22 ENSDART00000089108
fndc3ba
fibronectin type III domain containing 3Ba
chr22_-_18179214 0.22 ENSDART00000129576
si:ch211-125m10.6
si:ch211-125m10.6
chr24_+_22022109 0.21 ENSDART00000133686
ropn1l
rhophilin associated tail protein 1-like
chr5_-_29587351 0.21 ENSDART00000136446
ENSDART00000051434
entpd2a.1
ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 1
chr7_-_29292206 0.21 ENSDART00000086753
dapk2a
death-associated protein kinase 2a
chr1_-_39977551 0.20 ENSDART00000139354
stox2a
storkhead box 2a
chr7_+_38898208 0.20 ENSDART00000172251
creb3l1
cAMP responsive element binding protein 3-like 1
chr16_-_24598042 0.20 ENSDART00000156407
ENSDART00000154072
si:dkey-56f14.4
si:dkey-56f14.4
chr4_-_78026285 0.19 ENSDART00000168273
CCT2
chaperonin containing TCP1 subunit 2
chr18_+_41313999 0.19 ENSDART00000048985
veph1
ventricular zone expressed PH domain-containing 1
chr23_-_15090782 0.18 ENSDART00000133624
si:ch211-218g4.2
si:ch211-218g4.2
chr3_-_50046004 0.18 ENSDART00000109544
si:ch1073-100f3.2
si:ch1073-100f3.2
chr19_+_31183495 0.18 ENSDART00000088618
meox2b
mesenchyme homeobox 2b
chr16_+_34111919 0.18 ENSDART00000134037
ENSDART00000006061
ENSDART00000140552
tcea3
transcription elongation factor A (SII), 3
chr21_+_29227224 0.17 ENSDART00000013641
adra1ba
adrenoceptor alpha 1Ba
chr16_+_14684916 0.16 ENSDART00000138611
col14a1a
collagen, type XIV, alpha 1a
chr9_+_44034790 0.16 ENSDART00000166110
ENSDART00000176954
itga4
integrin alpha 4
chr9_+_48415043 0.14 ENSDART00000159930
lrp2a
low density lipoprotein receptor-related protein 2a
chr16_-_9869056 0.14 ENSDART00000149312
ncalda
neurocalcin delta a
chr14_-_22152064 0.14 ENSDART00000115422
nudcd2
NudC domain containing 2
chr19_+_1831911 0.14 ENSDART00000166653
ptk2aa
protein tyrosine kinase 2aa
chr12_-_20409794 0.14 ENSDART00000077936
lcmt1
leucine carboxyl methyltransferase 1
chr3_-_16039619 0.13 ENSDART00000143324
spsb3a
splA/ryanodine receptor domain and SOCS box containing 3a
chr12_+_20678187 0.13 ENSDART00000146762
st6galnac1.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 1
chr1_+_23398405 0.13 ENSDART00000102646
rhoh
ras homolog family member H
chr21_+_32338897 0.13 ENSDART00000110137
si:ch211-247j9.1
si:ch211-247j9.1
chr9_+_44034990 0.13 ENSDART00000162406
itga4
integrin alpha 4
chr7_-_54677143 0.12 ENSDART00000163748
ccnd1
cyclin D1
chr11_+_6650966 0.12 ENSDART00000131236
si:dkey-246j7.1
si:dkey-246j7.1
chr13_+_24584401 0.12 ENSDART00000057599
fuom
fucose mutarotase
chr15_+_3284684 0.12 ENSDART00000179778
foxo1a
forkhead box O1 a
chr7_-_18700364 0.11 ENSDART00000112359
si:ch211-119e14.9
si:ch211-119e14.9
chr7_-_52498175 0.11 ENSDART00000129769
cgnl1
cingulin-like 1
chr5_-_24201437 0.11 ENSDART00000114113
sox19a
SRY (sex determining region Y)-box 19a
chr7_-_7823662 0.11 ENSDART00000167652
cxcl8b.3
chemokine (C-X-C motif) ligand 8b, duplicate 3
chr7_-_20836625 0.10 ENSDART00000192566
cldn15a
claudin 15a
chr4_-_21466480 0.10 ENSDART00000139962
pawr
PRKC, apoptosis, WT1, regulator
chr24_+_22731228 0.10 ENSDART00000146733
si:dkey-225k4.1
si:dkey-225k4.1
chr2_-_7431590 0.09 ENSDART00000185699
asip2b
agouti signaling protein, nonagouti homolog (mouse) 2b
chr5_-_16218777 0.09 ENSDART00000141698
kremen1
kringle containing transmembrane protein 1
chr7_+_22585447 0.09 ENSDART00000149144
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr10_+_17776981 0.09 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr16_+_11029762 0.08 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr9_+_32358514 0.08 ENSDART00000144608
plcl1
phospholipase C like 1
chr13_-_42560662 0.08 ENSDART00000124898
CR792417.1

chr25_-_16666886 0.08 ENSDART00000155764
slc25a18
solute carrier family 25 (glutamate carrier), member 18
chr18_+_41820039 0.08 ENSDART00000128345
pgr
progesterone receptor
chr3_+_53240562 0.08 ENSDART00000031234
stxbp2
syntaxin binding protein 2
chr12_+_20149707 0.08 ENSDART00000181942
foxj1b
forkhead box J1b
chr15_+_17848590 0.08 ENSDART00000168940
zgc:113279
zgc:113279
chr14_-_46897067 0.08 ENSDART00000058789
qdpra
quinoid dihydropteridine reductase a
chr23_+_27740788 0.07 ENSDART00000053871
dhh
desert hedgehog
chr22_-_6144428 0.07 ENSDART00000106118
si:dkey-19a16.4
si:dkey-19a16.4
chr8_+_10823069 0.06 ENSDART00000081341
mapk13
mitogen-activated protein kinase 13
chr12_+_28854963 0.06 ENSDART00000153227
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr13_+_23843712 0.06 ENSDART00000057611
oprm1
opioid receptor, mu 1
chr12_+_20149305 0.06 ENSDART00000126676
ENSDART00000153327
foxj1b
forkhead box J1b
chr6_+_23752593 0.06 ENSDART00000164366
zgc:158654
zgc:158654
chr2_+_37838259 0.06 ENSDART00000136796
parp2
poly (ADP-ribose) polymerase 2
chr2_-_26476030 0.05 ENSDART00000145262
ENSDART00000132125
acadm
acyl-CoA dehydrogenase medium chain
chr6_+_37308716 0.05 ENSDART00000085498
ptger3
prostaglandin E receptor 3 (subtype EP3)
chr17_+_23462972 0.05 ENSDART00000112959
ENSDART00000192168
ankrd1a
ankyrin repeat domain 1a (cardiac muscle)
chr10_+_16188761 0.05 ENSDART00000193244
ctxn3
cortexin 3
chr19_-_3303995 0.04 ENSDART00000105150
si:ch211-133n4.9
si:ch211-133n4.9
chr3_+_34846201 0.04 ENSDART00000055263
itga3a
integrin, alpha 3a
chr6_+_27361978 0.04 ENSDART00000065238
crocc2
ciliary rootlet coiled-coil, rootletin family member 2
chr10_-_40968095 0.04 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr22_+_20208185 0.04 ENSDART00000142748
si:dkey-110c1.7
si:dkey-110c1.7
chr4_-_17803784 0.04 ENSDART00000187195
spi2
Spi-2 proto-oncogene
chr4_+_10366532 0.03 ENSDART00000189901
kcnd2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr8_-_9684872 0.03 ENSDART00000132158
ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr25_-_3139805 0.03 ENSDART00000166625
epx
eosinophil peroxidase
chr20_-_52271262 0.03 ENSDART00000135463
rhpn1
rhophilin, Rho GTPase binding protein 1
chr18_-_6766354 0.03 ENSDART00000132611
adm2b
adrenomedullin 2b
chr8_+_9684479 0.03 ENSDART00000132031
mon1ba
MON1 secretory trafficking family member Ba
chr11_+_355305 0.03 ENSDART00000147426
pdrg1
p53 and DNA-damage regulated 1
chr8_-_24970790 0.02 ENSDART00000141267
si:ch211-199o1.2
si:ch211-199o1.2
chr2_+_3201345 0.02 ENSDART00000130349
wnt9a
wingless-type MMTV integration site family, member 9A
chr19_+_41520892 0.02 ENSDART00000182218
ENSDART00000115123
crtc2
CREB regulated transcription coactivator 2
chr20_-_20610812 0.01 ENSDART00000181870
ppm1ab
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr4_+_18489207 0.01 ENSDART00000135276
si:dkey-202b22.5
si:dkey-202b22.5
chr20_-_52271015 0.01 ENSDART00000074307
rhpn1
rhophilin, Rho GTPase binding protein 1
chr24_-_10897511 0.01 ENSDART00000145593
ENSDART00000102484
ENSDART00000066784
fam49bb
family with sequence similarity 49, member Bb
chr24_+_26742226 0.01 ENSDART00000079721
ghsrb
growth hormone secretagogue receptor b
chr7_+_57341805 0.00 ENSDART00000115222
rxfp3.3a2
relaxin/insulin-like family peptide receptor 3.3a2
chr18_+_9493720 0.00 ENSDART00000053125
sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr7_-_41468751 0.00 ENSDART00000150146
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b

Network of associatons between targets according to the STRING database.

First level regulatory network of scrt1a+scrt1b+scrt2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.1 0.3 GO:0002676 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.2 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.8 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.4 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.8 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.4 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343) negative regulation of lipid transport(GO:0032369)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.2 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0033700 phospholipid efflux(GO:0033700)
0.0 0.1 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.1 GO:0070293 renal absorption(GO:0070293)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0045471 response to ethanol(GO:0045471)
0.0 0.1 GO:0044058 regulation of digestive system process(GO:0044058)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0038046 enkephalin receptor activity(GO:0038046)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.1 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors