Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for sox10

Z-value: 0.82

Motif logo

Transcription factors associated with sox10

Gene Symbol Gene ID Gene Info
ENSDARG00000077467 SRY-box transcription factor 10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox10dr11_v1_chr3_+_1492174_14921740.835.3e-03Click!

Activity profile of sox10 motif

Sorted Z-values of sox10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_14098028 1.74 ENSDART00000018432
hatching enzyme 1, tandem dupliate 2
chr10_+_44042033 1.53 ENSDART00000190006
ENSDART00000046172
crystallin, beta A4
chr7_+_39444843 1.42 ENSDART00000143999
ENSDART00000173554
ENSDART00000173698
ENSDART00000173754
ENSDART00000144075
ENSDART00000138192
ENSDART00000145457
ENSDART00000141750
ENSDART00000103056
ENSDART00000142946
ENSDART00000173748
troponin T type 3b (skeletal, fast)
chr23_-_21471022 1.19 ENSDART00000104206
hairy-related 4, tandem duplicate 2
chr6_-_39313027 1.09 ENSDART00000012644
keratin 4
chr15_-_108414 1.02 ENSDART00000170044
apolipoprotein A-Ib
chr5_-_71705191 0.97 ENSDART00000187767
adenylate kinase 1
chr14_+_46313135 0.95 ENSDART00000172902
crystallin, beta A1, like 1
chr14_+_46313396 0.92 ENSDART00000047525
crystallin, beta A1, like 1
chr13_+_22675802 0.91 ENSDART00000145538
ENSDART00000143312
zgc:193505
chr20_-_43775495 0.89 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matrilin 3a
chr17_-_122680 0.87 ENSDART00000066430
actin, alpha, cardiac muscle 1b
chr1_-_19845378 0.87 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
glyoxylate reductase/hydroxypyruvate reductase b
chr13_+_43247936 0.86 ENSDART00000126850
ENSDART00000165331
SPARC related modular calcium binding 2
chr16_-_45917322 0.86 ENSDART00000060822
antifreeze protein type IV
chr6_-_43092175 0.86 ENSDART00000084389
leucine rich repeat neuronal 1
chr18_-_6634424 0.84 ENSDART00000062423
ENSDART00000179955
troponin I, skeletal, slow c
chr23_+_36063599 0.82 ENSDART00000103147
homeobox C12a
chr21_-_25741411 0.82 ENSDART00000101211
claudin h
chr21_+_26389391 0.81 ENSDART00000077197
thymosin, beta
chr17_+_45305645 0.81 ENSDART00000172488
calpain 3a, (p94)
chr21_-_28920245 0.80 ENSDART00000132884
CXXC finger protein 5a
chr21_-_26495700 0.79 ENSDART00000109379
CD248 molecule, endosialin b
chr23_-_10175898 0.75 ENSDART00000146185
keratin 5
chr25_+_20089986 0.75 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr22_-_15587360 0.74 ENSDART00000142717
ENSDART00000138978
tropomyosin 4a
chr5_-_28625515 0.74 ENSDART00000190782
ENSDART00000179736
ENSDART00000131729
tenascin C
chr8_-_16697912 0.73 ENSDART00000076542
retinal pigment epithelium-specific protein 65b
chr8_-_50147948 0.71 ENSDART00000149010
haptoglobin
chr8_-_46509194 0.68 ENSDART00000038924
sulfotransferase family 1, cytosolic sulfotransferase 1
chr2_+_26179096 0.68 ENSDART00000024662
phospholipid phosphatase related 3a
chr3_+_15505275 0.66 ENSDART00000141714
nuclear protein 1
chr10_+_21780250 0.65 ENSDART00000183782
protocadherin 1 gamma 9
chr3_+_24197934 0.65 ENSDART00000055609
activating transcription factor 4b
chr12_-_30841679 0.65 ENSDART00000105594
crystallin, gamma MX
chr21_+_20771082 0.64 ENSDART00000079732
3-oxoacid CoA transferase 1b
chr7_-_7398350 0.64 ENSDART00000012637
zgc:101810
chr8_+_39619087 0.64 ENSDART00000134822
musashi RNA-binding protein 1
chr2_-_43653328 0.63 ENSDART00000037808
integrin, beta 1b.2
chr10_+_9550419 0.62 ENSDART00000064977
si:ch211-243g18.2
chr23_+_36144487 0.62 ENSDART00000082473
homeobox C3a
chr24_+_25069609 0.61 ENSDART00000115165
APC membrane recruitment protein 2
chr24_-_40700596 0.60 ENSDART00000162635
slow myosin heavy chain 2
chr12_-_7655322 0.60 ENSDART00000181162
ankyrin 3b
chr2_-_39017838 0.60 ENSDART00000048838
retinol binding protein 2b, cellular
chr6_+_52804267 0.60 ENSDART00000065681
matrilin 4
chr21_-_20342096 0.59 ENSDART00000065659
retinol binding protein 4, like
chr21_-_35853245 0.59 ENSDART00000172245
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr18_+_40525408 0.59 ENSDART00000132833
von Willebrand factor A domain containing 7
chr24_+_22485710 0.57 ENSDART00000146058
si:dkey-40h20.1
chr5_-_25582721 0.55 ENSDART00000123986
annexin A1a
chr2_+_22042745 0.55 ENSDART00000132039
thymocyte selection-associated high mobility group box
chr13_-_46429220 0.53 ENSDART00000149125
ENSDART00000098269
ENSDART00000150061
ENSDART00000080916
fibroblast growth factor receptor 2
chr14_-_51855047 0.52 ENSDART00000088912
complexin 1
chr9_-_7683799 0.51 ENSDART00000102713
si:ch73-199e17.1
chr21_-_32301109 0.51 ENSDART00000139890
CDC-like kinase 4b
chr9_-_21918963 0.51 ENSDART00000090782
LIM domain 7a
chr20_+_34511678 0.51 ENSDART00000061588
paired related homeobox 1b
chr4_-_38877924 0.51 ENSDART00000177741
zinc finger protein 1127
chr10_+_35422802 0.51 ENSDART00000147303
HERV-H LTR-associating 2a, tandem duplicate 1
chr5_-_25012428 0.51 ENSDART00000146872
EMI domain containing 1
chr23_+_27068225 0.50 ENSDART00000054238
major intrinsic protein of lens fiber a
chr11_-_3629201 0.50 ENSDART00000136577
ENSDART00000132121
inter-alpha-trypsin inhibitor heavy chain 3a
chr19_-_21716593 0.50 ENSDART00000155126
zinc finger protein 516
chr6_+_45932276 0.50 ENSDART00000103491
retinol binding protein 7b, cellular
chr14_+_36220479 0.49 ENSDART00000148319
paired-like homeodomain 2
chr23_+_24705424 0.48 ENSDART00000104029
C1q and TNF related 12
chr13_+_51579851 0.48 ENSDART00000163847
NK6 homeobox 2
chr23_-_31506854 0.48 ENSDART00000131352
ENSDART00000138625
ENSDART00000133002
EYA transcriptional coactivator and phosphatase 4
chr3_-_29977495 0.48 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr15_-_3736149 0.47 ENSDART00000182986
lysophosphatidic acid receptor 6a
chr5_-_20205075 0.47 ENSDART00000051611
D-amino-acid oxidase, tandem duplicate 3
chr20_+_40237441 0.47 ENSDART00000168928
si:ch211-199i15.5
chr4_-_193762 0.46 ENSDART00000169667
protein tyrosine phosphatase, receptor type, O
chr13_-_13294847 0.46 ENSDART00000125883
ENSDART00000013534
fibroblast growth factor receptor 3
chr5_-_64883082 0.46 ENSDART00000064983
ENSDART00000139066
keratin, type 1, gene c5
chr21_-_20341836 0.45 ENSDART00000176689
retinol binding protein 4, like
chr3_-_58226583 0.45 ENSDART00000187429
im:6904045
chr9_-_18911608 0.45 ENSDART00000138785
si:dkey-239h2.3
chr23_-_30787932 0.45 ENSDART00000135771
myelin transcription factor 1a
chr2_+_38161318 0.44 ENSDART00000044264
matrix metallopeptidase 14b (membrane-inserted)
chr21_-_2310064 0.44 ENSDART00000169520
si:ch211-241b2.1
chr2_-_32768951 0.44 ENSDART00000004712
beaded filament structural protein 2, phakinin
chr16_-_26731928 0.43 ENSDART00000135860
ring finger protein 41, like
chr12_+_2399130 0.41 ENSDART00000075179
V-set and transmembrane domain containing 4b
chr16_+_9762261 0.41 ENSDART00000020654
proteasome 26S subunit, non-ATPase 4b
chr10_+_21793670 0.41 ENSDART00000168918
protocadherin 1 gamma c 6
chr20_-_26042070 0.40 ENSDART00000140255
si:dkey-12h9.6
chr23_+_4890693 0.40 ENSDART00000023537
troponin C type 1a (slow)
chr17_-_42213285 0.39 ENSDART00000140549
NK2 homeobox 2a
chr1_-_625875 0.39 ENSDART00000167331
amyloid beta (A4) precursor protein a
chr3_-_26204867 0.39 ENSDART00000103748
glycerophosphodiester phosphodiesterase domain containing 3a
chr13_+_28854438 0.39 ENSDART00000193407
ENSDART00000189554

chr1_+_34696503 0.39 ENSDART00000186106

chr13_+_25428677 0.39 ENSDART00000186284
si:dkey-51a16.9
chr7_-_69636502 0.38 ENSDART00000126739
tetraspanin 5a
chr15_-_31514818 0.38 ENSDART00000153978
high mobility group box 1b
chr1_+_41849152 0.38 ENSDART00000053685
spermine oxidase
chr15_+_35691783 0.37 ENSDART00000183994

chr20_+_7584211 0.37 ENSDART00000132481
ENSDART00000127975
ENSDART00000144551
biogenesis of lysosomal organelles complex-1, subunit 2
chr19_+_9786722 0.36 ENSDART00000138310
calcium channel, voltage-dependent, gamma subunit 6a
chr21_+_44684577 0.36 ENSDART00000099528
sprouty homolog 4 (Drosophila)
chr1_-_51474974 0.36 ENSDART00000152719
sprouty-related, EVH1 domain containing 2a
chr21_-_25756119 0.36 ENSDART00000002341
claudin c
chr15_-_17870090 0.36 ENSDART00000155066
activating transcription factor 5b
chr25_-_27541621 0.36 ENSDART00000130678
sperm adhesion molecule 1
chr12_-_19102736 0.36 ENSDART00000180364
cold shock domain containing C2, RNA binding a
chr22_-_16180849 0.36 ENSDART00000090390
vascular cell adhesion molecule 1b
chr15_+_28368644 0.36 ENSDART00000168453
solute carrier family 43 (amino acid system L transporter), member 2a
chr3_+_41922114 0.35 ENSDART00000138280
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_-_24612871 0.35 ENSDART00000155614
ENSDART00000154787
ENSDART00000155983
ENSDART00000156519
FXYD domain containing ion transport regulator 6 like
chr6_-_19023468 0.35 ENSDART00000184729
septin 9b
chr6_+_36459897 0.35 ENSDART00000104248
ENSDART00000145753
leucine rich repeat containing 15
chr6_+_2048920 0.34 ENSDART00000153568
quattro
chr7_-_35126374 0.34 ENSDART00000141211
hydroxysteroid (11-beta) dehydrogenase 2
chr25_-_12788370 0.33 ENSDART00000158551
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr2_-_42960353 0.32 ENSDART00000098303
otoconin 90
chr1_+_17376922 0.32 ENSDART00000145068
FAT atypical cadherin 1a
chr14_-_8080416 0.31 ENSDART00000045109
zgc:92242
chr7_+_20019125 0.31 ENSDART00000186391
B-cell CLL/lymphoma 6, member B
chr8_+_42998944 0.31 ENSDART00000048819
Ras association (RalGDS/AF-6) domain family member 2a
chr23_+_9067131 0.31 ENSDART00000144533
cerebral cavernous malformation 2-like
chr3_+_56645710 0.30 ENSDART00000193978

chr5_+_67662430 0.30 ENSDART00000137700
ENSDART00000142586
si:dkey-70b23.2
chr13_-_1151410 0.29 ENSDART00000007231
proteasome subunit beta 1
chr14_+_18785727 0.29 ENSDART00000184452
si:ch211-111e20.1
chr17_-_20717845 0.29 ENSDART00000150037
ankyrin 3b
chr13_+_29771463 0.29 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
paired box 2a
chr5_+_53482597 0.28 ENSDART00000180333

chr3_-_16250527 0.28 ENSDART00000146699
ENSDART00000141181
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr21_+_45733871 0.28 ENSDART00000187285
ENSDART00000193018
zgc:77058
chr5_+_59252701 0.28 ENSDART00000144829
uroplakin 3b
chr23_+_42304602 0.28 ENSDART00000166004
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr4_-_71110826 0.27 ENSDART00000167431
si:dkeyp-80d11.1
chr7_-_39552314 0.27 ENSDART00000134174
solute carrier family 22, member 18
chr23_-_4925131 0.27 ENSDART00000138805
tafazzin
chr13_+_23169227 0.27 ENSDART00000169447
sorbin and SH3 domain containing 1
chr23_+_22658700 0.27 ENSDART00000192248
enolase 1a, (alpha)
chr14_-_45394704 0.27 ENSDART00000173078
ENSDART00000125970
si:ch211-168f7.5
chr8_-_14151051 0.27 ENSDART00000090427
si:dkey-6n6.1
chr6_-_6993046 0.26 ENSDART00000053304
si:ch211-114n24.6
chr16_+_53125918 0.25 ENSDART00000102170

chr8_-_24113575 0.25 ENSDART00000099692
ENSDART00000186211
DNA cross-link repair 1B
chr4_+_72742212 0.25 ENSDART00000171021
RAB3A interacting protein (rabin3)
chr4_+_75314247 0.25 ENSDART00000162365

chr15_-_42206890 0.25 ENSDART00000015843
paired box 3b
chr4_+_26357221 0.25 ENSDART00000187684
ENSDART00000101545
ENSDART00000148296
ENSDART00000171433
troponin I, skeletal, slow d
chr17_-_42213822 0.25 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr8_+_26205471 0.25 ENSDART00000131888
cadherin, EGF LAG seven-pass G-type receptor 3
chr10_+_44984946 0.25 ENSDART00000182520
H2A histone family, member Vb
chr8_+_23521974 0.25 ENSDART00000188130
ENSDART00000129378
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr7_-_29625509 0.25 ENSDART00000173723
RAR-related orphan receptor A, paralog b
chr12_-_34035364 0.24 ENSDART00000087065
TIMP metallopeptidase inhibitor 2a
chr6_-_35487413 0.24 ENSDART00000102461
regulator of G protein signaling 8
chr9_+_27411502 0.24 ENSDART00000143994
si:dkey-193n17.9
chr7_+_57677120 0.24 ENSDART00000110623
arylsulfatase family, member J
chr14_+_18782610 0.24 ENSDART00000164468
si:ch211-111e20.1
chr16_-_32233463 0.24 ENSDART00000102016
calcium homeostasis modulator family member 6
chr11_-_11471857 0.24 ENSDART00000030103
keratin 94
chr2_-_10896745 0.24 ENSDART00000114609
CUB domain containing protein 2
chr12_-_30777540 0.24 ENSDART00000126466
ectonucleoside triphosphate diphosphohydrolase 1
chr7_+_39758714 0.24 ENSDART00000111278
sortilin-related VPS10 domain containing receptor 2
chr19_+_31404686 0.24 ENSDART00000078459
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr8_-_31938364 0.24 ENSDART00000137647
si:dkey-250l23.4
chr13_-_8229977 0.23 ENSDART00000139728
si:ch211-250c4.4
chr17_+_24848976 0.23 ENSDART00000062917
connexin 35.4
chr4_+_15819728 0.23 ENSDART00000101613
leucine-rich repeats and guanylate kinase domain containing
chr19_-_11031145 0.23 ENSDART00000151375
ENSDART00000027598
ENSDART00000137865
ENSDART00000188025
tropomyosin 3
chr10_-_17284055 0.23 ENSDART00000167464
G protein subunit alpha z
chr20_+_25568694 0.23 ENSDART00000063107
ENSDART00000063128
cytochrome P450, family 2, subfamily P, polypeptide 7
chr4_-_27301356 0.23 ENSDART00000100444
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr4_+_15954293 0.22 ENSDART00000132695
si:dkey-117n7.4
chr22_-_17489040 0.22 ENSDART00000141286
si:ch211-197g15.6
chr12_-_5418340 0.22 ENSDART00000028043
NOC3-like DNA replication regulator
chr1_+_15137901 0.22 ENSDART00000111475
protocadherin 7a
chr5_-_69041102 0.22 ENSDART00000161561
ankyrin 1, erythrocytic a
chr2_-_31521764 0.22 ENSDART00000140523
mannose receptor, C type 1b
chr10_+_21737745 0.22 ENSDART00000170498
ENSDART00000167997
protocadherin 1 gamma 18
chr18_-_14836862 0.21 ENSDART00000124843
metastasis suppressor 1-like a
chr20_-_22476255 0.21 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr23_+_43954809 0.21 ENSDART00000164080
corin, serine peptidase
chr1_-_59102320 0.21 ENSDART00000193379
si:zfos-2330d3.7
chr15_+_44053244 0.21 ENSDART00000059550
leucine rich repeat containing 51
chr4_-_77432218 0.21 ENSDART00000158683
solute carrier organic anion transporter family, member 1D1
chr3_+_14558188 0.20 ENSDART00000143904
erythropoietin receptor
chr2_-_32769759 0.20 ENSDART00000178951
beaded filament structural protein 2, phakinin
chr17_-_24564674 0.20 ENSDART00000105435
ENSDART00000135086
ATP-binding cassette, sub-family H, member 1
chr22_-_20309283 0.20 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
chr5_-_33460959 0.20 ENSDART00000085636
si:ch211-182d3.1
chr11_-_42554290 0.20 ENSDART00000130573
ATPase H+ transporting accessory protein 1 like a
chr1_+_35862550 0.20 ENSDART00000132118
si:ch211-194g2.4
chr18_-_48547564 0.20 ENSDART00000138607
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr23_-_3758637 0.19 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
high mobility group AT-hook 1a
chr7_-_38698583 0.19 ENSDART00000173900
ENSDART00000126737
CD59 molecule (CD59 blood group)
chr21_-_17603182 0.19 ENSDART00000020048
ENSDART00000177270
gelsolin a
chr6_-_54290227 0.19 ENSDART00000050483
SAM pointed domain containing ETS transcription factor
chr17_-_19022990 0.19 ENSDART00000154186
fibronectin leucine rich transmembrane protein 2
chr3_-_50443607 0.19 ENSDART00000074036
recoverin a
chr3_+_30500968 0.19 ENSDART00000103447
si:dkey-13n23.3
chr14_-_30897177 0.19 ENSDART00000087918
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3b

Network of associatons between targets according to the STRING database.

First level regulatory network of sox10

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.2 0.6 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.0 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.2 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.7 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2 0.7 GO:1901825 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 1.0 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.5 GO:0046324 regulation of glucose import(GO:0046324)
0.1 0.5 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.9 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.5 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.6 GO:2001280 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.5 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.4 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.8 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 0.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.4 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 2.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.4 GO:0055016 hypochord development(GO:0055016)
0.1 1.4 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.1 0.5 GO:0006833 water transport(GO:0006833)
0.1 0.5 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.2 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.1 0.3 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 1.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.3 GO:0034650 cortisol metabolic process(GO:0034650)
0.0 0.5 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.2 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.4 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.7 GO:0009712 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 0.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.3 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.9 GO:0042476 odontogenesis(GO:0042476)
0.0 0.9 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.2 GO:0043091 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 4.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.1 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.1 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0072028 nephron morphogenesis(GO:0072028)
0.0 0.1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0 0.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.9 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.1 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.1 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.6 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 0.4 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0048899 anterior lateral line development(GO:0048899)
0.0 0.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0045095 keratin filament(GO:0045095)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 3.5 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0042627 chylomicron(GO:0042627)
0.1 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.9 GO:0005869 dynactin complex(GO:0005869)
0.1 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.7 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 1.0 GO:0034632 retinol transporter activity(GO:0034632)
0.1 1.4 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.6 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.6 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.5 GO:0015250 water channel activity(GO:0015250)
0.1 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 3.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.7 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.1 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.5 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs