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PRJNA207719: Tissue specific transcriptome profiling

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Results for arxa

Z-value: 1.25

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Transcription factors associated with arxa

Gene Symbol Gene ID Gene Info
ENSDARG00000058011 aristaless related homeobox a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arxadr11_v1_chr24_-_23942722_23942722-0.847.8e-02Click!

Activity profile of arxa motif

Sorted Z-values of arxa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_11775269 1.83 ENSDART00000140272
keratin 96
chr3_-_59297532 1.26 ENSDART00000187991

chr20_-_37813863 1.22 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr4_-_9891874 1.18 ENSDART00000067193
adrenomedullin 2a
chr9_-_9415000 1.09 ENSDART00000146210
si:ch211-214p13.9
chr12_-_35830625 0.91 ENSDART00000180028

chr25_-_21031007 0.81 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr12_+_22580579 0.78 ENSDART00000171725
ENSDART00000192290
capping protein (actin filament), gelsolin-like b
chr11_+_705727 0.78 ENSDART00000165366
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr14_+_901847 0.76 ENSDART00000166991
si:ch73-208h1.2
chr2_-_36918709 0.74 ENSDART00000084876
zgc:153654
chr23_-_33350990 0.73 ENSDART00000144831
si:ch211-226m16.2
chr19_+_43780970 0.72 ENSDART00000063870
ribosomal protein L11
chr25_-_28674739 0.70 ENSDART00000067073
leucine rich repeat containing 10
chr14_+_34558480 0.67 ENSDART00000075170
pituitary tumor-transforming 1
chr23_-_30041065 0.66 ENSDART00000131209
ENSDART00000127192
coiled-coil domain containing 187
chr20_+_11731039 0.64 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
chr6_-_7720332 0.64 ENSDART00000135945
ribosomal protein SA
chr5_-_7199998 0.63 ENSDART00000167316

chr23_-_16485190 0.62 ENSDART00000155038
si:dkeyp-100a5.4
chr1_+_44127292 0.60 ENSDART00000160542
calcium binding protein 2a
chr16_-_11798994 0.60 ENSDART00000135408
cornifelin
chr6_+_36839509 0.60 ENSDART00000190605
ENSDART00000104160
zgc:110788
chr19_+_2631565 0.59 ENSDART00000171487
family with sequence similarity 126, member A
chr7_-_50410524 0.56 ENSDART00000083346
huntingtin interacting protein K
chr23_+_4709607 0.56 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr13_+_24756486 0.54 ENSDART00000137074
collagen, type XVII, alpha 1b
chr13_-_31017960 0.53 ENSDART00000145287
WDFY family member 4
chr2_-_26596794 0.52 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr14_-_14659023 0.50 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr3_-_29941357 0.50 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
granulin a
chr20_-_43663494 0.49 ENSDART00000144564

chr9_-_32656656 0.49 ENSDART00000078399
granzyme 3, tandem duplicate 1
chr6_+_39905021 0.49 ENSDART00000064904
endonuclease, polyU-specific
chr12_-_48188928 0.48 ENSDART00000184384
phosphatase domain containing, paladin 1a
chr25_-_13319112 0.48 ENSDART00000179885
si:ch211-194m7.8
chr22_+_19366866 0.47 ENSDART00000137301
si:dkey-21e2.12
chr24_-_36680261 0.47 ENSDART00000059507
chemokine (C-C motif) receptor 10
chr8_+_26059677 0.46 ENSDART00000009178
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr16_-_51271962 0.46 ENSDART00000164021
ENSDART00000046420
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr13_-_36798204 0.46 ENSDART00000012357
salvador family WW domain containing protein 1
chr17_+_20589553 0.46 ENSDART00000154447
si:ch73-288o11.4
chr10_+_11261576 0.46 ENSDART00000155333
hydroxysteroid dehydrogenase like 2
chr20_+_25586099 0.45 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr14_-_4145594 0.44 ENSDART00000077348
caspase 3, apoptosis-related cysteine peptidase b
chr8_+_28695914 0.44 ENSDART00000033386
osteoclast stimulatory transmembrane protein
chr12_-_36521767 0.43 ENSDART00000110290
unc-13 homolog D (C. elegans)
chr5_-_42083363 0.43 ENSDART00000162596
chemokine (C-X-C motif) ligand 11, duplicate 5
chr21_+_43328685 0.43 ENSDART00000109620
ENSDART00000139668
septin 8a
chr23_-_37575030 0.42 ENSDART00000031875
torsin family 1 like 3
chr16_+_23799622 0.42 ENSDART00000046922
RAB13, member RAS oncogene family
chr5_-_42082730 0.42 ENSDART00000135625
chemokine (C-X-C motif) ligand 11, duplicate 5
chr18_+_13275735 0.42 ENSDART00000148127
phospholipase C, gamma 2
chr23_-_42232124 0.41 ENSDART00000149944
glutathione peroxidase 7
chr23_+_26733232 0.41 ENSDART00000035080
zgc:158263
chr7_+_21272833 0.41 ENSDART00000052942
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr24_-_37640705 0.40 ENSDART00000066583
zgc:112496
chr6_-_55399214 0.39 ENSDART00000168367
cathepsin A
chr15_-_4528326 0.39 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr25_+_11008419 0.38 ENSDART00000156589
major histocompatibility complex class I LIA
chr7_+_24573721 0.38 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr5_+_71802014 0.38 ENSDART00000124939
ENSDART00000097164
LIM homeobox 3
chr24_+_19415124 0.38 ENSDART00000186931
sulfatase 1
chr13_-_2010191 0.38 ENSDART00000161021
ENSDART00000124134
GDNF family receptor alpha like
chr20_+_19176959 0.38 ENSDART00000163276
ENSDART00000020099
BLK proto-oncogene, Src family tyrosine kinase
chr8_+_25079470 0.36 ENSDART00000000744
synaptophysin-like 2b
chr15_-_38129845 0.36 ENSDART00000057095
si:dkey-24p1.1
chr20_+_25225112 0.36 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
monooxygenase, DBH-like 1
chr3_+_27798094 0.35 ENSDART00000075100
ENSDART00000151437
calcium regulated heat stable protein 1
chr9_+_24065855 0.35 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
leucine rich repeat (in FLII) interacting protein 1a
chr21_-_44081540 0.34 ENSDART00000130833

chr24_+_29912509 0.33 ENSDART00000168422
ferric-chelate reductase 1b
chr20_+_38458084 0.32 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr19_+_42955280 0.32 ENSDART00000141225
fatty acid binding protein 3, muscle and heart
chr22_+_7738966 0.32 ENSDART00000147073
si:ch73-44m9.5
chr18_-_46258612 0.32 ENSDART00000153930
si:dkey-244a7.1
chr6_-_40842768 0.31 ENSDART00000076160
musculoskeletal, embryonic nuclear protein 1a
chr7_+_19495905 0.31 ENSDART00000125584
ENSDART00000173774
si:ch211-212k18.8
chr23_+_1029450 0.31 ENSDART00000189196
si:zfos-905g2.1
chr2_-_10877765 0.31 ENSDART00000100607
cell division cycle 7 homolog (S. cerevisiae)
chr13_+_646700 0.30 ENSDART00000006892
tumor protein p53 binding protein, 2a
chr23_+_36460239 0.30 ENSDART00000172441
LIM domain and actin binding 1a
chr7_+_22543963 0.29 ENSDART00000101528
cholinergic receptor, nicotinic, beta 1 (muscle)
chr13_-_37229245 0.29 ENSDART00000140923
si:dkeyp-77c8.5
chr15_-_35134918 0.28 ENSDART00000157196
si:ch211-272b8.7
chr18_+_39106722 0.28 ENSDART00000122377
BCL2 like 10
chr14_-_413273 0.28 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr1_-_17715493 0.28 ENSDART00000133027
si:dkey-256e7.8
chr20_-_51355465 0.27 ENSDART00000151620
ENSDART00000151690
ENSDART00000110289
t-complex-associated-testis-expressed 1
chr14_+_40874608 0.27 ENSDART00000168448
si:ch211-106m9.1
chr21_-_19314618 0.27 ENSDART00000188744
glycerol-3-phosphate acyltransferase 3
chr22_-_5529241 0.27 ENSDART00000157893

chr15_+_41932069 0.27 ENSDART00000143007
si:ch211-191a16.2
chr5_-_4418555 0.26 ENSDART00000170158
apolipoprotein O, a
chr1_+_51721851 0.26 ENSDART00000040397
peroxiredoxin 2
chr7_+_26173751 0.26 ENSDART00000065131
si:ch211-196f2.7
chr19_+_12237945 0.26 ENSDART00000190034
grainyhead-like transcription factor 2b
chr21_-_45363871 0.26 ENSDART00000075443
ENSDART00000182078
ENSDART00000151106
zgc:56064
chr3_-_19368435 0.25 ENSDART00000132987
sphingosine-1-phosphate receptor 5a
chr12_-_28363111 0.25 ENSDART00000016283
ENSDART00000164156
proteasome 26S subunit, non-ATPase 11b
chr12_-_4185554 0.25 ENSDART00000152313
si:dkey-32n7.7
chr2_-_38284648 0.25 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
chr24_-_29586082 0.24 ENSDART00000136763
vav 3 guanine nucleotide exchange factor a
chr10_-_3138859 0.24 ENSDART00000190606
ubiquitin-conjugating enzyme E2L 3a
chr24_+_37640626 0.24 ENSDART00000008047
WD repeat domain 24
chr21_+_45223194 0.24 ENSDART00000150902
si:ch73-269m14.3
chr25_+_22320738 0.24 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr10_-_3138403 0.24 ENSDART00000183365
ubiquitin-conjugating enzyme E2L 3a
chr22_+_737211 0.24 ENSDART00000017305
zinc finger protein 76
chr25_+_30131055 0.23 ENSDART00000152705
apoptosis inhibitor 5
chr16_+_23984179 0.23 ENSDART00000175879
apolipoprotein C-II
chr1_+_47499888 0.23 ENSDART00000027624
STN1, CST complex subunit
chr10_-_2788668 0.23 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2 (absent, small, or homeotic)-like (Drosophila)
chr4_+_20566371 0.22 ENSDART00000127576

chr7_+_2969661 0.22 ENSDART00000158382

chr7_+_19495379 0.22 ENSDART00000180514
si:ch211-212k18.8
chr7_+_34453185 0.22 ENSDART00000173875
ENSDART00000173921
ENSDART00000173995
si:cabz01009626.1
chr10_+_38610741 0.22 ENSDART00000126444
matrix metallopeptidase 13a
chr10_-_43771447 0.22 ENSDART00000052307
arrestin domain containing 3b
chr25_+_13620555 0.22 ENSDART00000163642
si:ch211-172l8.4
chr2_+_9990491 0.22 ENSDART00000011906
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr8_+_17167876 0.22 ENSDART00000134665
centromere protein H
chr5_+_69747417 0.21 ENSDART00000153717
si:ch211-275j6.5
chr9_-_30555725 0.21 ENSDART00000079222
chromatin assembly factor 1, subunit B
chr20_-_9095105 0.21 ENSDART00000140792
OMA1 zinc metallopeptidase
chr14_+_30568961 0.21 ENSDART00000184303
mitochondrial ribosomal protein L11
chr6_+_12527725 0.20 ENSDART00000149328
serine/threonine kinase 24b (STE20 homolog, yeast)
chr9_+_22351443 0.20 ENSDART00000080054
crystallin, gamma S3
chr16_-_38118003 0.20 ENSDART00000058667
si:dkey-23o4.6
chr24_-_38657683 0.20 ENSDART00000154843
si:ch1073-164k15.3
chr1_-_45616470 0.20 ENSDART00000150165
activating transcription factor 7 interacting protein
chr23_+_11347313 0.20 ENSDART00000135406
cell adhesion molecule L1-like a
chr22_+_19407531 0.20 ENSDART00000141060
si:dkey-78l4.2
chr4_-_67980261 0.20 ENSDART00000182305
si:ch211-223k15.1
chr11_-_39118882 0.20 ENSDART00000113185
ENSDART00000156526
adaptor-related protein complex 5, beta 1 subunit
chr6_+_8598428 0.20 ENSDART00000032118
ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)
chr2_-_9989919 0.19 ENSDART00000180213
ENSDART00000184369
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr2_-_59205393 0.19 ENSDART00000056417
ENSDART00000182452
ENSDART00000141876
finTRIM family, member 30
chr3_-_58798377 0.19 ENSDART00000161248
si:ch73-281f12.4
chr3_+_30501135 0.19 ENSDART00000165869
si:dkey-13n23.3
chr1_+_35985813 0.19 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
chr16_+_19029297 0.18 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr1_+_47165842 0.18 ENSDART00000053152
ENSDART00000167051
carbonyl reductase 1
chr20_-_40360571 0.18 ENSDART00000144768
sphingomyelin phosphodiesterase, acid-like 3A
chr16_-_32013913 0.18 ENSDART00000030282
ENSDART00000138701
glutathione S-transferase kappa 1
chr19_-_5669122 0.17 ENSDART00000112211
si:ch211-264f5.2
chr4_+_51551318 0.17 ENSDART00000190283
si:dkey-165e24.1
chr20_+_18661624 0.17 ENSDART00000152136
ENSDART00000126959
tumor necrosis factor, alpha-induced protein 2a
chr3_+_32118670 0.17 ENSDART00000055287
ENSDART00000111688
zgc:109934
chr9_+_43799829 0.17 ENSDART00000186240
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr4_-_9909371 0.17 ENSDART00000102656
si:dkey-22l11.6
chr5_-_16472719 0.17 ENSDART00000162071
piwi-like RNA-mediated gene silencing 2
chr15_+_25156382 0.17 ENSDART00000171092
info solute carrier family 35, member F2, like
chr8_+_49065348 0.17 ENSDART00000032277
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr1_-_54063520 0.17 ENSDART00000171722
single-pass membrane protein with aspartate-rich tail 1b
chr18_+_7073130 0.17 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
chr23_-_19225709 0.16 ENSDART00000080099
O-acyl-ADP-ribose deacylase 1
chr2_+_1988036 0.16 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr11_-_16152400 0.16 ENSDART00000123665
actin related protein 2/3 complex, subunit 4, like
chr4_+_5255041 0.16 ENSDART00000137966
coiled-coil domain containing 167
chr11_+_31324335 0.16 ENSDART00000088093
signal-induced proliferation-associated 1 like 2
chr13_+_7049823 0.16 ENSDART00000178997
ENSDART00000161443
ribonuclease T2
chr3_+_29445473 0.16 ENSDART00000020381
GRB2-related adaptor protein 2a
chr24_-_7995960 0.16 ENSDART00000186594
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr3_-_34052882 0.16 ENSDART00000151463
immunoglobulin heavy variable 11-1
chr6_-_52788213 0.16 ENSDART00000179880
recombination signal binding protein for immunoglobulin kappa J region-like
chr7_-_60156409 0.15 ENSDART00000006802
chaperonin containing TCP1, subunit 7 (eta)
chr16_-_7793457 0.15 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr5_-_11809710 0.15 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
neurofibromin 2a (merlin)
chr6_+_40922572 0.14 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr7_-_30677104 0.14 ENSDART00000188360
myosin IE, a
chr14_-_7045009 0.14 ENSDART00000112082
RUN and FYVE domain containing 1
chr5_+_65871688 0.14 ENSDART00000175217
family with sequence similarity 163 member B
chr2_-_45331115 0.14 ENSDART00000158003
si:dkey-13n23.3
chr5_+_66433287 0.14 ENSDART00000170757
kinetochore associated 1
chr19_-_47323267 0.13 ENSDART00000190077

chr18_+_35128685 0.13 ENSDART00000151579
si:ch211-195m9.3
chr19_+_1688727 0.13 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr16_-_13818061 0.12 ENSDART00000132982
ENSDART00000144856
leukocyte receptor cluster (LRC) member 9
chr10_+_26652859 0.12 ENSDART00000079174
HIV-1 Tat specific factor 1
chr5_+_66312359 0.12 ENSDART00000137534
MALT paracaspase 1
chr14_+_30795559 0.12 ENSDART00000006132
cofilin 1
chr17_+_50524573 0.12 ENSDART00000187974

chr13_+_35339182 0.12 ENSDART00000019323
jagged 1b
chr21_-_30082414 0.12 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr9_-_34937025 0.12 ENSDART00000137888
cell division cycle 16 homolog (S. cerevisiae)
chr20_-_5291012 0.11 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr11_-_41853874 0.11 ENSDART00000002556
MRT4 homolog, ribosome maturation factor
chr4_+_59845617 0.11 ENSDART00000167626
ENSDART00000123157
si:dkey-196n19.2
chr14_-_7137808 0.11 ENSDART00000054803
tRNA phosphotransferase 1
chr22_+_30137374 0.11 ENSDART00000187808
adducin 3 (gamma) a
chr4_-_69428110 0.11 ENSDART00000160607
si:ch211-145h19.3
chr2_+_10878406 0.11 ENSDART00000091497
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr6_+_7533601 0.11 ENSDART00000057823
proliferation-associated 2G4, a
chr15_+_37965953 0.11 ENSDART00000154192
si:dkey-238d18.10
chr1_-_57629639 0.10 ENSDART00000158984
zmp:0000001289
chr20_-_2949028 0.10 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cyclin-dependent kinase 19
chr17_-_49978986 0.10 ENSDART00000154728
collagen, type XII, alpha 1a
chr8_-_53044300 0.10 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr23_-_36303216 0.10 ENSDART00000188720
chromobox homolog 5 (HP1 alpha homolog, Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of arxa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.4 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.1 0.4 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 0.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.7 GO:0006032 chitin catabolic process(GO:0006032)
0.1 0.5 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.7 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.4 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.5 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.8 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.0 0.7 GO:0033048 negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.3 GO:0010522 regulation of calcium ion transport into cytosol(GO:0010522) regulation of release of sequestered calcium ion into cytosol(GO:0051279)
0.0 0.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.4 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.9 GO:0050821 protein stabilization(GO:0050821)
0.0 0.9 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304) negative regulation of fatty acid metabolic process(GO:0045922)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.2 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.1 GO:0010965 regulation of mitotic sister chromatid separation(GO:0010965)
0.0 0.1 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.2 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626)
0.0 0.4 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.2 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0004568 chitinase activity(GO:0004568)
0.1 0.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.2 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.5 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation