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PRJNA207719: Tissue specific transcriptome profiling

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Results for bach1a+bach1b+bach2a+bach2b

Z-value: 1.34

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Transcription factors associated with bach1a+bach1b+bach2a+bach2b

Gene Symbol Gene ID Gene Info
ENSDARG00000002196 BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
ENSDARG00000004074 BTB and CNC homology 1, basic leucine zipper transcription factor 2b
ENSDARG00000036569 BTB and CNC homology 1, basic leucine zipper transcription factor 2a
ENSDARG00000062553 BTB and CNC homology 1, basic leucine zipper transcription factor 1 a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bach2adr11_v1_chr17_+_15674052_156740520.951.4e-02Click!
bach2bdr11_v1_chr20_-_24022558_240225580.847.6e-02Click!
bach1adr11_v1_chr15_-_8191992_81919920.761.4e-01Click!
bach1bdr11_v1_chr10_+_25369254_25369254-0.583.0e-01Click!

Activity profile of bach1a+bach1b+bach2a+bach2b motif

Sorted Z-values of bach1a+bach1b+bach2a+bach2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_21832441 2.37 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
myelin basic protein a
chr19_-_103289 2.00 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr1_+_31113951 1.85 ENSDART00000129362
eukaryotic translation elongation factor 1 alpha 1b
chr14_+_34486629 1.75 ENSDART00000131861
thymosin beta 2
chr2_+_47582681 1.66 ENSDART00000187579
secretogranin II (chromogranin C), b
chr21_-_30545121 1.48 ENSDART00000019199
RAB39B, member RAS oncogene family a
chr2_+_47582488 1.47 ENSDART00000149967
secretogranin II (chromogranin C), b
chr2_+_47581997 1.40 ENSDART00000112579
secretogranin II (chromogranin C), b
chr16_+_14033121 1.37 ENSDART00000135844
RUN and SH3 domain containing 1
chr1_-_53750522 1.35 ENSDART00000190755
v-akt murine thymoma viral oncogene homolog 3b
chr20_+_34915945 1.35 ENSDART00000153064
synaptosomal-associated protein, 25a
chr12_-_10315039 1.32 ENSDART00000152680
peptide YYb
chr3_+_7617353 1.29 ENSDART00000165551
zgc:109949
chr1_+_12766351 1.21 ENSDART00000165785
protocadherin 10a
chr1_-_40227166 1.20 ENSDART00000146680
si:ch211-113e8.3
chr21_+_3093419 1.20 ENSDART00000162520
SHC adaptor protein 3
chr2_-_155270 1.19 ENSDART00000131177
adenylate cyclase 1b
chr7_+_23875269 1.15 ENSDART00000101406
RAB39B, member RAS oncogene family b
chr8_+_7359294 1.12 ENSDART00000121708
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr23_-_15878879 1.11 ENSDART00000010119
eukaryotic translation elongation factor 1 alpha 2
chr1_+_41690402 1.10 ENSDART00000177298
F-box protein 41
chr16_-_12984631 1.07 ENSDART00000184863
calcium channel, voltage-dependent, gamma subunit 7b
chr15_+_28989573 1.06 ENSDART00000076648
CAP-GLY domain containing linker protein 3
chr5_-_22501663 1.05 ENSDART00000133174
si:dkey-27p18.5
chr1_+_46598764 1.04 ENSDART00000053240
calcium binding protein 39-like
chr19_-_5805923 1.02 ENSDART00000134340
si:ch211-264f5.8
chr2_+_24177006 1.01 ENSDART00000132582
microtubule associated protein 4 like
chr3_+_45401472 0.98 ENSDART00000156693
BAI1-associated protein 3
chr22_-_3595439 0.96 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr2_+_50862527 0.94 ENSDART00000169800
ENSDART00000158847
ENSDART00000160900
adenylate cyclase activating polypeptide 1a (pituitary) receptor type I
chr19_-_36675023 0.93 ENSDART00000132471
CUB and Sushi multiple domains 2
chr7_+_26649319 0.92 ENSDART00000173823
ENSDART00000101053
tumor protein p53 inducible protein 11a
chr5_-_14564878 0.91 ENSDART00000160511
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr7_-_52963493 0.88 ENSDART00000052029
cocaine- and amphetamine-regulated transcript 3
chr2_+_48288461 0.88 ENSDART00000141495
hes family bHLH transcription factor 6
chr8_+_24861264 0.87 ENSDART00000099607
solute carrier family 6 (neutral amino acid transporter), member 17
chr8_+_24854600 0.87 ENSDART00000156570
solute carrier family 6 (neutral amino acid transporter), member 17
chr13_-_21701323 0.86 ENSDART00000164112
si:dkey-191g9.7
chr21_-_42100471 0.80 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_-_20678300 0.79 ENSDART00000088639
WSC domain containing 2
chr25_+_21324588 0.79 ENSDART00000151842
leucine rich repeat neuronal 3a
chr1_+_46598502 0.77 ENSDART00000132861
calcium binding protein 39-like
chr2_-_9544161 0.77 ENSDART00000124425
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24, like
chr10_+_4235998 0.76 ENSDART00000169328
phospholipid phosphatase related 1
chr5_+_20147830 0.76 ENSDART00000098727
SV2 related protein a
chr13_-_37545487 0.75 ENSDART00000131269
synaptotagmin XVI
chr17_-_7861219 0.75 ENSDART00000148604
spectrin repeat containing, nuclear envelope 1b
chr8_-_13211527 0.74 ENSDART00000090541
si:ch73-61d6.3
chr2_+_24177190 0.74 ENSDART00000099546
microtubule associated protein 4 like
chr16_-_32837806 0.73 ENSDART00000003997
si:dkey-165n16.5
chr2_+_20430366 0.72 ENSDART00000155108
si:ch211-153l6.6
chr1_+_41849152 0.72 ENSDART00000053685
spermine oxidase
chr25_-_7999756 0.72 ENSDART00000159908
calcium/calmodulin-dependent protein kinase 1Db
chr17_-_45247332 0.71 ENSDART00000016815
tau tubulin kinase 2a
chr15_+_40188076 0.70 ENSDART00000063779
EF-hand domain family, member D1
chr21_-_45613564 0.70 ENSDART00000160324

chr4_-_4535189 0.69 ENSDART00000057519
zgc:194209
chr15_+_32867420 0.69 ENSDART00000159442
doublecortin-like kinase 1b
chr18_-_18850302 0.67 ENSDART00000131965
ENSDART00000167624
transglutaminase 2, like
chr19_+_24394560 0.67 ENSDART00000142506
si:dkey-81h8.1
chr5_+_15350954 0.66 ENSDART00000140990
ENSDART00000137287
ENSDART00000061653
phosphatidylethanolamine binding protein 1
chr5_+_20035284 0.64 ENSDART00000191808
small G protein signaling modulator 1a
chr15_-_13254480 0.63 ENSDART00000190499
zgc:172282
chr10_+_37145007 0.62 ENSDART00000131777
CUE domain containing 1a
chr7_-_5487593 0.62 ENSDART00000136594
Rho guanine nucleotide exchange factor (GEF) 11
chr1_+_2190714 0.61 ENSDART00000132126
muscleblind-like splicing regulator 2
chr6_+_10534752 0.61 ENSDART00000090874
potassium channel, voltage gated eag related subfamily H, member 7
chr23_-_28239750 0.60 ENSDART00000003548
zinc finger protein 385A
chr24_-_40009446 0.60 ENSDART00000087422
amine oxidase, copper containing 1
chr22_-_11954861 0.59 ENSDART00000131611
si:dkeyp-4h4.1
chr14_-_34044369 0.59 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr18_-_9046805 0.59 ENSDART00000134224
glutamate receptor, metabotropic 3
chr24_-_21973365 0.58 ENSDART00000081204
ENSDART00000030592
acyl-CoA thioesterase 9, tandem duplicate 1
chr16_+_34479064 0.57 ENSDART00000159965
si:ch211-255i3.4
chr19_+_10396042 0.57 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr2_+_42112503 0.57 ENSDART00000136022
corticotropin releasing hormone a
chr12_-_17147473 0.55 ENSDART00000106035
STAM binding protein-like 1
chr18_+_3169579 0.55 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
p21 protein (Cdc42/Rac)-activated kinase 1
chr3_+_20156956 0.55 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr5_+_59534286 0.54 ENSDART00000189341
GTF2I repeat domain containing 1
chr18_+_9635178 0.53 ENSDART00000183486
piccolo presynaptic cytomatrix protein b
chr15_-_30832171 0.52 ENSDART00000152414
ENSDART00000152790
musashi RNA-binding protein 2b
chr4_-_1801519 0.52 ENSDART00000188604
ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr5_+_44804791 0.51 ENSDART00000122288
cathepsin La
chr17_-_45247151 0.51 ENSDART00000186230
tau tubulin kinase 2a
chr10_-_32877348 0.51 ENSDART00000018977
ENSDART00000133421
RAB guanine nucleotide exchange factor (GEF) 1
chr22_+_24220937 0.49 ENSDART00000165380
ubiquitin carboxyl-terminal hydrolase L5
chr19_-_10395683 0.49 ENSDART00000109488
zgc:194578
chr11_+_19370717 0.49 ENSDART00000165906
prickle homolog 2b
chr21_-_30254185 0.49 ENSDART00000101054
DnaJ (Hsp40) homolog, subfamily C, member 18
chr18_+_3243292 0.48 ENSDART00000166580
p21 protein (Cdc42/Rac)-activated kinase 1
chr24_+_26039464 0.48 ENSDART00000131017
tyrosine kinase, non-receptor, 2a
chr3_-_51142942 0.47 ENSDART00000160789
si:ch211-148f13.1
chr12_-_35386910 0.47 ENSDART00000153453
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr19_-_7495006 0.46 ENSDART00000148836
regulatory factor X, 5
chr10_-_27566481 0.45 ENSDART00000078920
autism susceptibility candidate 2a
chr2_+_9822319 0.45 ENSDART00000144078
ENSDART00000144371
annexin A13, like
chr11_-_3334248 0.44 ENSDART00000154314
ENSDART00000121861
peripherin
chr25_-_11378623 0.44 ENSDART00000166586
ectodermal-neural cortex 2
chr25_+_18583877 0.44 ENSDART00000148741
MET proto-oncogene, receptor tyrosine kinase
chr13_+_43247936 0.43 ENSDART00000126850
ENSDART00000165331
SPARC related modular calcium binding 2
chr11_+_19370447 0.43 ENSDART00000186154
prickle homolog 2b
chr24_-_5691956 0.42 ENSDART00000189112
deleted in autism 1b
chr23_+_45339684 0.42 ENSDART00000149410
ENSDART00000102441
PC4 and SFRS1 interacting protein 1b
chr17_+_19626479 0.41 ENSDART00000044993
ENSDART00000131863
regulator of G protein signaling 7a
chr14_-_6936731 0.40 ENSDART00000162196
CDC-like kinase 4a
chr2_+_9821757 0.40 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr19_-_40776608 0.40 ENSDART00000179941
calcitonin receptor
chr14_-_493029 0.39 ENSDART00000115093
zgc:172215
chr3_+_24986145 0.39 ENSDART00000055428
chromobox homolog 7a
chr9_+_29323163 0.39 ENSDART00000184908
oxoglutarate (alpha-ketoglutarate) receptor 1b
chr8_+_48966165 0.38 ENSDART00000165425
AP2 associated kinase 1a
chr19_+_33093395 0.38 ENSDART00000019459
family with sequence similarity 91, member A1
chr25_-_173165 0.38 ENSDART00000193594

chr19_+_23932259 0.38 ENSDART00000139040
si:dkey-222b8.1
chr20_-_16849306 0.37 ENSDART00000131395
ENSDART00000027582
breast cancer metastasis-suppressor 1-like b
chr2_-_39759059 0.37 ENSDART00000007333
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr19_+_33093577 0.37 ENSDART00000180317
family with sequence similarity 91, member A1
chr21_+_26620867 0.37 ENSDART00000176008
estrogen-related receptor alpha
chr20_-_16548912 0.36 ENSDART00000137601
checkpoint suppressor 1
chr14_-_44841335 0.36 ENSDART00000173011
si:dkey-109l4.6
chr11_+_11267829 0.36 ENSDART00000026814
ENSDART00000173346
ENSDART00000151926
protein tyrosine phosphatase type IVA, member 1
chr16_+_13818500 0.36 ENSDART00000135245
folliculin
chr20_-_21994901 0.36 ENSDART00000004984
dishevelled associated activator of morphogenesis 1b
chr4_+_1600034 0.35 ENSDART00000146779
solute carrier family 38, member 2
chr18_+_15841449 0.35 ENSDART00000141800
ENSDART00000091349
early endosome antigen 1
chr5_+_44805028 0.34 ENSDART00000141198
cathepsin La
chr14_-_17588345 0.34 ENSDART00000143486
selenoprotein T, 2
chr6_+_43903209 0.34 ENSDART00000006435
G protein-coupled receptor 27
chr20_-_32446406 0.33 ENSDART00000026635
nuclear receptor subfamily 2, group E, member 1
chr14_-_44841503 0.33 ENSDART00000179114
si:dkey-109l4.6
chr5_+_21931124 0.33 ENSDART00000137627
si:ch73-92i20.1
chr22_+_17399124 0.32 ENSDART00000145769
RAB GTPase activating protein 1-like
chr17_-_31044803 0.32 ENSDART00000185941
ENSDART00000152016
echinoderm microtubule associated protein like 1
chr25_+_14697247 0.32 ENSDART00000180747
metallophosphoesterase domain containing 2b
chr3_+_35498119 0.32 ENSDART00000178963
trinucleotide repeat containing 6a
chr18_-_18849916 0.32 ENSDART00000142422
transglutaminase 2, like
chr16_+_13818743 0.32 ENSDART00000090191
folliculin
chr18_-_15155962 0.31 ENSDART00000111333
mitochondrial transcription termination factor 2
chr5_-_42180205 0.31 ENSDART00000145247
family with sequence similarity 222, member Ba
chr4_-_77506362 0.30 ENSDART00000174387
ENSDART00000181181

chr15_-_11955485 0.30 ENSDART00000160286
si:dkey-202l22.3
chr9_+_7030016 0.30 ENSDART00000148047
ENSDART00000148181
inositol polyphosphate-4-phosphatase type I Aa
chr2_-_7605121 0.29 ENSDART00000182099

chr11_+_11267493 0.28 ENSDART00000148425
protein tyrosine phosphatase type IVA, member 1
chr18_-_13360106 0.28 ENSDART00000091512
c-Maf inducing protein
chr4_+_45274792 0.28 ENSDART00000150295
zinc finger protein 1138
chr16_-_21181128 0.28 ENSDART00000133403
phosphodiesterase 11a, like
chr10_+_31222433 0.28 ENSDART00000185080
transmembrane protein 218
chr19_+_4139065 0.27 ENSDART00000172524
si:dkey-218f9.10
chr19_-_31035155 0.27 ENSDART00000161882
basic leucine zipper and W2 domains 2
chr5_-_19052184 0.25 ENSDART00000133330
family with sequence similarity 214, member B
chr2_-_3038904 0.25 ENSDART00000186795
guanylate kinase 1a
chr2_-_37837056 0.25 ENSDART00000158179
ENSDART00000160317
ENSDART00000171409
methyltransferase like 17
chr7_-_19638319 0.24 ENSDART00000163686
si:ch211-212k18.4
chr8_-_34402839 0.24 ENSDART00000180173
ENSDART00000191588
ENSDART00000186376
GTPase activating protein and VPS9 domains 1
chr1_-_10577945 0.24 ENSDART00000179237
ENSDART00000040502
ENSDART00000186876
transient receptor potential cation channel, subfamily C, member 5a
chr1_+_58677434 0.24 ENSDART00000158488

chr3_+_24197934 0.24 ENSDART00000055609
activating transcription factor 4b
chr11_+_34760628 0.24 ENSDART00000087216
si:dkey-202e22.2
chr4_-_73787702 0.23 ENSDART00000136328
ENSDART00000150546
si:dkey-262g12.3
chr11_-_22371105 0.23 ENSDART00000146873
transmembrane protein 183A
chr19_+_551963 0.23 ENSDART00000110495
A kinase (PRKA) anchor protein 9
chr7_+_22688781 0.23 ENSDART00000173509
UDP glucuronosyltransferase 5 family, polypeptide G1
chr5_-_42123794 0.23 ENSDART00000051135
ER membrane protein complex subunit 6
chr15_+_24704798 0.22 ENSDART00000192470
si:dkey-151p21.7
chr7_-_29723761 0.22 ENSDART00000173560
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr24_+_80653 0.21 ENSDART00000158473
ENSDART00000129135
reversion-inducing-cysteine-rich protein with kazal motifs
chr1_+_56447107 0.21 ENSDART00000091924

chr8_+_43053519 0.21 ENSDART00000147178
prion protein a
chr13_+_1430094 0.21 ENSDART00000169888
si:ch211-165e15.1
chr10_+_38775959 0.21 ENSDART00000192990
Down syndrome cell adhesion molecule a
chr12_+_47280839 0.21 ENSDART00000187574
ryanodine receptor 2
chr5_+_34549845 0.21 ENSDART00000139317
allograft inflammatory factor 1-like
chr4_+_68087932 0.21 ENSDART00000150494
zinc finger protein 1096
chr22_-_6562618 0.20 ENSDART00000106100
zgc:171490
chr18_+_17537344 0.20 ENSDART00000025782
nucleoporin 93
chr18_-_8396192 0.20 ENSDART00000193830
si:ch211-220f12.4
chr3_-_24205339 0.20 ENSDART00000157135
si:dkey-110g7.8
chr10_+_2529037 0.19 ENSDART00000123467
zmp:0000001301
chr10_+_38775408 0.19 ENSDART00000125045
Down syndrome cell adhesion molecule a
chr9_+_28140089 0.19 ENSDART00000046880
pleckstrin homology domain containing, family M, member 3
chr17_+_58211 0.19 ENSDART00000157642
si:ch1073-209e23.1
chr1_+_52137528 0.19 ENSDART00000007079
ENSDART00000074265
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr18_+_15182965 0.19 ENSDART00000137018
si:ch73-62b13.1
chr4_+_40063572 0.19 ENSDART00000146710

chr16_+_48714048 0.19 ENSDART00000148709
ENSDART00000150121
bromodomain containing 2b
chr22_+_36547670 0.18 ENSDART00000125991
ENSDART00000186372
armadillo repeat containing 9
chr17_+_7595356 0.18 ENSDART00000130625
si:dkeyp-110a12.4
chr4_+_76431531 0.18 ENSDART00000174278

chr5_-_37157510 0.18 ENSDART00000166710
leucine-rich repeats and calponin homology (CH) domain containing 2
chr9_-_23181062 0.18 ENSDART00000192578
LY6/PLAUR domain containing 6B
chr25_+_336503 0.17 ENSDART00000160395

chr12_-_3077395 0.17 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_-_36746837 0.17 ENSDART00000189276
ENSDART00000085228
phosphoinositide-3-kinase, regulatory subunit 4
chr6_-_35309661 0.17 ENSDART00000114960
nitric oxide synthase 1 (neuronal) adaptor protein a
chr1_-_22726233 0.17 ENSDART00000140920
prominin 1 b
chr9_+_41024973 0.17 ENSDART00000014660
ENSDART00000144467
ORMDL sphingolipid biosynthesis regulator 1
chr7_-_5396154 0.17 ENSDART00000172980
Rho guanine nucleotide exchange factor (GEF) 11
chr17_+_28675120 0.16 ENSDART00000159067
HECT domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of bach1a+bach1b+bach2a+bach2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0015824 proline transport(GO:0015824)
0.5 2.0 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.2 1.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 1.0 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 0.8 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.4 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.1 4.7 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 0.9 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.5 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.7 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.3 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 2.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.2 GO:0097324 melanocyte migration(GO:0097324)
0.1 1.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 1.1 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 1.3 GO:0007631 feeding behavior(GO:0007631)
0.1 0.3 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 0.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 1.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 3.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.6 GO:0001964 startle response(GO:0001964)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.4 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.4 GO:0006868 glutamine transport(GO:0006868)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.9 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.4 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.5 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.5 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 1.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 3.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.4 GO:0042476 odontogenesis(GO:0042476)
0.0 0.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.9 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0030431 sleep(GO:0030431)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.1 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.0 0.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:1904292 regulation of ERAD pathway(GO:1904292)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 2.4 GO:0043209 myelin sheath(GO:0043209)
0.1 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 4.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.2 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.2 GO:0071914 prominosome(GO:0071914)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.2 2.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.7 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.4 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.5 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.6 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.5 GO:0005035 death receptor activity(GO:0005035)
0.1 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.7 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.1 3.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.8 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 1.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis