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PRJNA207719: Tissue specific transcriptome profiling

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Results for ctcf

Z-value: 1.05

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Transcription factors associated with ctcf

Gene Symbol Gene ID Gene Info
ENSDARG00000056621 CCCTC-binding factor (zinc finger protein)
ENSDARG00000113285 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ctcfdr11_v1_chr18_+_22285992_222860290.941.8e-02Click!

Activity profile of ctcf motif

Sorted Z-values of ctcf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_56463167 0.53 ENSDART00000123392
RAB11B, member RAS oncogene family, b
chr21_+_45626136 0.42 ENSDART00000158742
interferon regulatory factor 1b
chr9_-_12594759 0.40 ENSDART00000021266
transformer 2 beta homolog
chr18_+_907266 0.40 ENSDART00000171729
pyruvate kinase M1/2a
chr20_-_29864390 0.39 ENSDART00000161834
ENSDART00000132278
ring finger protein 144ab
chr21_+_17024002 0.39 ENSDART00000080628
actin related protein 2/3 complex, subunit 3
chr9_-_12595003 0.38 ENSDART00000184900
transformer 2 beta homolog
chr17_+_6276559 0.37 ENSDART00000131075
dual specificity phosphatase 23b
chr5_+_57320113 0.36 ENSDART00000036331
ATPase H+ transporting V1 subunit G1
chr22_-_57177 0.36 ENSDART00000163959

chr6_+_39836474 0.36 ENSDART00000112637
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr20_-_30931139 0.36 ENSDART00000006778
ENSDART00000146376
acetyl-CoA acetyltransferase 2
chr19_-_3916075 0.35 ENSDART00000161799
si:ch73-281i18.7
chr25_+_31122806 0.34 ENSDART00000067039
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8a
chr18_-_14677936 0.34 ENSDART00000111995
si:dkey-238o13.4
chr8_+_7144066 0.32 ENSDART00000146306
solute carrier family 6 (neurotransmitter transporter), member 6a
chr3_-_21280373 0.32 ENSDART00000003939
synaptogyrin 1a
chr19_-_3896514 0.32 ENSDART00000161346
si:ch73-281i18.3
chr5_-_6377865 0.31 ENSDART00000031775
zgc:73226
chr8_-_11324143 0.31 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr12_-_31794908 0.31 ENSDART00000105583
ENSDART00000153449
N-acetyltransferase 9 (GCN5-related, putative)
chr19_-_3906369 0.30 ENSDART00000160299
ENSDART00000169205
si:ch73-281i18.4
chr19_-_3925801 0.30 ENSDART00000129570
ENSDART00000163138
si:ch73-281i18.6
chr14_-_44790817 0.29 ENSDART00000098640
glyoxylate reductase/hydroxypyruvate reductase a
chr19_-_7070691 0.28 ENSDART00000168755
TAP binding protein (tapasin), tandem duplicate 2
chr9_-_29643628 0.28 ENSDART00000101177
SPRY domain containing 7b
chr10_+_26926654 0.27 ENSDART00000078980
ENSDART00000100289
RAB1B, member RAS oncogene family b
chr2_-_40135942 0.27 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
eph receptor A4a
chr13_-_46429220 0.27 ENSDART00000149125
ENSDART00000098269
ENSDART00000150061
ENSDART00000080916
fibroblast growth factor receptor 2
chr12_-_48374728 0.27 ENSDART00000153403
ENSDART00000188117
DnaJ (Hsp40) homolog, subfamily B, member 12b
chr3_+_24050043 0.27 ENSDART00000151788
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr22_-_372723 0.26 ENSDART00000112895
si:zfos-1324h11.5
chr12_-_3077395 0.26 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_7807298 0.26 ENSDART00000191355
ankyrin 3b
chr1_-_8651718 0.26 ENSDART00000133319
actin, beta 1
chr7_+_24049776 0.25 ENSDART00000166559
embryonal Fyn-associated substrate
chr7_+_30787903 0.25 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr19_-_33274978 0.25 ENSDART00000020301
ENSDART00000114714
family with sequence similarity 92, member A1
chr9_-_30243393 0.25 ENSDART00000089539
si:dkey-100n23.3
chr20_+_49895220 0.25 ENSDART00000097865
integrator complex subunit 9
chr1_+_218524 0.25 ENSDART00000109529
transmembrane and coiled-coil domains 3
chr3_-_45777226 0.25 ENSDART00000192849
H3 histone, family 3B.1
chr11_+_25157374 0.25 ENSDART00000019450
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr19_+_20785724 0.24 ENSDART00000038942
ADNP homeobox 2b
chr17_+_17955063 0.24 ENSDART00000104999
coiled-coil domain containing 85C, a
chr1_+_45958904 0.23 ENSDART00000108528
Rho guanine nucleotide exchange factor (GEF) 7b
chr21_+_261490 0.23 ENSDART00000177919
Janus kinase 2a
chr19_-_29437108 0.23 ENSDART00000052108
ENSDART00000074497
fibronectin type III domain containing 5b
chr1_-_45577980 0.23 ENSDART00000160961
activating transcription factor 7 interacting protein
chr25_+_28823952 0.23 ENSDART00000067072
nuclear transcription factor Y, beta b
chr6_+_59967994 0.23 ENSDART00000050457
zgc:65895
chr7_-_50917255 0.22 ENSDART00000022918
ankyrin repeat domain 46b
chr1_-_22851481 0.22 ENSDART00000054386
quinoid dihydropteridine reductase b1
chr13_-_40499296 0.22 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr4_+_12931763 0.22 ENSDART00000016382
wnt inhibitory factor 1
chr1_+_22851261 0.21 ENSDART00000193925
general transcription factor IIE, polypeptide 2, beta
chr5_+_52039067 0.21 ENSDART00000143276
SET binding protein 1
chr6_+_48041759 0.21 ENSDART00000140086
si:dkey-92f12.2
chr5_+_55934129 0.21 ENSDART00000050969
transmembrane protein 150Ab
chr1_+_22851745 0.21 ENSDART00000138235
ENSDART00000016488
general transcription factor IIE, polypeptide 2, beta
chr3_-_33417826 0.21 ENSDART00000084284
ABI family, member 3a
chr19_+_13420884 0.20 ENSDART00000160209
si:ch211-204a13.2
chr16_-_32672883 0.20 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
PNN-interacting serine/arginine-rich protein
chr15_-_16323750 0.20 ENSDART00000028500
nucleoredoxin
chr19_+_232536 0.20 ENSDART00000137880
synaptic Ras GTPase activating protein 1a
chr13_-_16191674 0.20 ENSDART00000147868
von Willebrand factor C domain containing 2
chr21_+_17005737 0.20 ENSDART00000101246
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr2_+_42724404 0.19 ENSDART00000075392
brain abundant, membrane attached signal protein 1
chr20_-_52338782 0.19 ENSDART00000109735
ENSDART00000132941
si:ch1073-287p18.1
chr20_+_26002534 0.19 ENSDART00000147845
nuclear receptor binding protein 1
chr5_-_29514689 0.19 ENSDART00000126018
ENSDART00000125175
euchromatic histone-lysine N-methyltransferase 1a
chr13_-_14908664 0.19 ENSDART00000138867
adaptor-related protein complex 5, sigma 1 subunit
chr10_+_6340478 0.19 ENSDART00000163182
ENSDART00000163722
tropomyosin 2 (beta)
chr1_+_34763539 0.19 ENSDART00000077725
ENSDART00000113808
zgc:172122
chr12_-_7639120 0.18 ENSDART00000126712
ENSDART00000126219
coiled-coil domain containing 6b
chr1_+_41690402 0.18 ENSDART00000177298
F-box protein 41
chr4_+_9177997 0.18 ENSDART00000057254
ENSDART00000154614
nuclear transcription factor Y, beta a
chr3_+_22057109 0.18 ENSDART00000153709
KAT8 regulatory NSL complex subunit 1b
chr15_+_22435460 0.18 ENSDART00000031976
transmembrane protein 136a
chr8_+_2757821 0.18 ENSDART00000051403
ENSDART00000160551
SH3-domain GRB2-like endophilin B2a
chr4_-_18512550 0.18 ENSDART00000045639
RAD50 interactor 1
chr3_-_22216442 0.18 ENSDART00000153613
microtubule-associated protein tau b
chr8_-_13364879 0.18 ENSDART00000063863
coiled-coil domain containing 124
chr25_-_554142 0.17 ENSDART00000028997
myosin IXAb
chr9_-_11655031 0.17 ENSDART00000044314
integrin, alpha V
chr19_-_7043355 0.17 ENSDART00000104845
TAP binding protein (tapasin), tandem duplicate 1
chr13_+_24834199 0.17 ENSDART00000101274
zgc:153981
chr10_+_33626344 0.17 ENSDART00000109563
beta 3-glucosyltransferase b
chr4_-_9667380 0.17 ENSDART00000189671
ENSDART00000133214
cyclin D binding myb-like transcription factor 1
chr8_+_25900049 0.17 ENSDART00000124300
ENSDART00000127618
ENSDART00000024009
ras homolog gene family, member Ab
chr21_+_15713097 0.17 ENSDART00000015841
glutathione S-transferase theta 1b
chr2_+_25019387 0.17 ENSDART00000142601
stromal antigen 1a
chr25_+_37130450 0.17 ENSDART00000183358
si:ch1073-174d20.1
chr19_+_18903533 0.17 ENSDART00000157523
ENSDART00000166562
solute carrier family 39 (zinc transporter), member 7
chr9_-_41507712 0.17 ENSDART00000135821
major facilitator superfamily domain containing 6b
chr25_-_12788370 0.17 ENSDART00000158551
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr24_-_41478917 0.17 ENSDART00000192192

chr11_+_40032790 0.17 ENSDART00000158809
si:dkey-264d12.1
chr5_-_32396929 0.17 ENSDART00000023977
F-box and WD repeat domain containing 2
chr13_-_27038407 0.16 ENSDART00000146712
coiled-coil domain containing 85A
chr16_-_8132742 0.16 ENSDART00000104323
SNF related kinase a
chr1_+_35194454 0.16 ENSDART00000165389
sc:d189
chr13_-_14908999 0.16 ENSDART00000112771
adaptor-related protein complex 5, sigma 1 subunit
chr22_-_3595439 0.16 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr19_+_24882845 0.16 ENSDART00000010580
si:ch211-195b13.1
chr13_-_33822550 0.16 ENSDART00000143703
fibronectin leucine rich transmembrane 3
chr19_+_233143 0.16 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr15_+_17441734 0.16 ENSDART00000153729
sorting nexin 19b
chr8_-_34427364 0.16 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
GTPase activating protein and VPS9 domains 1
chr21_-_18824434 0.16 ENSDART00000156333
si:dkey-112m2.1
chr12_-_33582382 0.16 ENSDART00000009794
ENSDART00000136617
tudor and KH domain containing
chr6_+_13779857 0.15 ENSDART00000154793
transmembrane protein 198b
chr3_+_40407352 0.15 ENSDART00000155112
trinucleotide repeat containing 18
chr5_-_54497319 0.15 ENSDART00000160492
aminolevulinate dehydratase
chr6_-_35046735 0.15 ENSDART00000143649
UDP-N-acetylglucosamine pyrophosphorylase 1
chr14_+_6954579 0.15 ENSDART00000060998
NME/NM23 family member 5
chr1_+_14283692 0.15 ENSDART00000017679
protein phosphatase 2, regulatory subunit B, gamma a
chr1_+_59154521 0.15 ENSDART00000130089
ENSDART00000152456
heme-binding protein soul5, like
chr25_-_13490744 0.15 ENSDART00000056721
lactate dehydrogenase D
chr25_+_19734038 0.14 ENSDART00000067354
zgc:101783
chr25_-_20730800 0.14 ENSDART00000172170
si:ch211-127m7.2
chr3_-_61354239 0.14 ENSDART00000154312
zinc finger protein 1134
chr9_+_219124 0.14 ENSDART00000161484
mitogen-activated protein kinase kinase kinase 12
chr23_-_20429741 0.14 ENSDART00000104334
TATA-box binding protein associated factor 13
chr10_-_7974155 0.14 ENSDART00000147368
ENSDART00000075524
oxysterol binding protein 2
chr11_+_22623284 0.14 ENSDART00000111850
si:ch211-86h15.1
chr20_+_19512727 0.14 ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr23_+_43954809 0.14 ENSDART00000164080
corin, serine peptidase
chr22_+_737211 0.14 ENSDART00000017305
zinc finger protein 76
chr22_+_35131890 0.13 ENSDART00000003303
ENSDART00000130581
ring finger protein 13
chr4_+_3478049 0.13 ENSDART00000153944
glutamate receptor, metabotropic 8a
chr24_+_37533728 0.13 ENSDART00000061203
ras homolog family member T2
chr7_+_29080684 0.13 ENSDART00000173709
ENSDART00000173576
ACD, shelterin complex subunit and telomerase recruitment factor
chr21_-_21824285 0.13 ENSDART00000030984
WD repeat domain 73
chr5_+_61941610 0.13 ENSDART00000168808
si:dkeyp-117b8.4
chr2_-_50298337 0.13 ENSDART00000155125
contactin associated protein like 2b
chr19_+_24068223 0.13 ENSDART00000141351
ENSDART00000100420
peroxisomal biogenesis factor 11 beta
chr9_+_22929675 0.13 ENSDART00000061299
translin
chr22_+_18786797 0.13 ENSDART00000141864
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr13_+_51853716 0.13 ENSDART00000175341
ENSDART00000187855

chr25_+_26921480 0.13 ENSDART00000155949
glutamate receptor, metabotropic 8b
chr15_+_6786757 0.12 ENSDART00000013278
sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
chr6_+_47846366 0.12 ENSDART00000064842
peptidyl arginine deiminase, type II
chr19_-_3886991 0.12 ENSDART00000162085
thyroid hormone receptor associated protein 3b
chr22_-_20403194 0.12 ENSDART00000010048
mitogen-activated protein kinase kinase 2a
chr10_+_2842923 0.12 ENSDART00000181895
YKT6 v-SNARE homolog (S. cerevisiae)
chr14_-_17588345 0.12 ENSDART00000143486
selenoprotein T, 2
chr10_+_11355841 0.12 ENSDART00000193067
ENSDART00000064215
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr16_+_23799622 0.11 ENSDART00000046922
RAB13, member RAS oncogene family
chr16_+_12812214 0.11 ENSDART00000124875
U2 small nuclear RNA auxiliary factor 2a
chr1_+_49878000 0.11 ENSDART00000047876
lymphoid enhancer-binding factor 1
chr12_+_18681477 0.11 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr5_+_58687541 0.11 ENSDART00000083015
ENSDART00000181902
coiled-coil domain containing 84
chr23_+_43950674 0.11 ENSDART00000167813
corin, serine peptidase
chr24_-_30096666 0.11 ENSDART00000183285
phospholipid phosphatase related 4b
chr13_-_35765028 0.11 ENSDART00000157391
endoplasmic reticulum lectin 1
chr19_-_7144548 0.11 ENSDART00000147177
ENSDART00000134850
proteasome subunit beta 8A
proteasome subunit beta 13a
chr5_+_41496490 0.11 ENSDART00000039369
Fanconi anemia, complementation group G
chr20_+_12702923 0.11 ENSDART00000163499
zgc:153383
chr18_+_44649804 0.11 ENSDART00000059063
EH-domain containing 2b
chr8_+_13364950 0.11 ENSDART00000159760
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr22_+_5135884 0.11 ENSDART00000141276
myeloid-derived growth factor
chr1_+_2301961 0.11 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_-_30248277 0.11 ENSDART00000133516
ENSDART00000077029
ER membrane protein complex subunit 10
chr6_+_45934682 0.11 ENSDART00000103489
centromere protein S
chr1_+_21937201 0.11 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr7_+_39758714 0.11 ENSDART00000111278
sortilin-related VPS10 domain containing receptor 2
chr10_-_40826657 0.11 ENSDART00000076304
proliferating cell nuclear antigen
chr14_-_30557127 0.11 ENSDART00000053936
prefoldin subunit 6
chr24_+_28935200 0.11 ENSDART00000017427
RNA-binding region (RNP1, RRM) containing 3
chr18_+_35229115 0.11 ENSDART00000129624
ENSDART00000184596
transforming growth factor beta regulator 1
chr3_-_22216771 0.11 ENSDART00000130546
microtubule-associated protein tau b
chr11_-_2270069 0.11 ENSDART00000189005
zinc finger protein 740a
chr20_-_54192130 0.10 ENSDART00000020834

chr16_+_12812472 0.10 ENSDART00000008535
U2 small nuclear RNA auxiliary factor 2a
chr18_+_8402129 0.10 ENSDART00000081154
ENSDART00000171974
PRP18 pre-mRNA processing factor 18 homolog (yeast)
chr8_+_26007988 0.10 ENSDART00000193948
ENSDART00000058100
xeroderma pigmentosum, complementation group C
chr19_+_40337457 0.10 ENSDART00000089547
ENSDART00000140857
family with sequence similarity 133, member B
chr4_-_75158035 0.10 ENSDART00000174353

chr3_-_26524934 0.10 ENSDART00000087118
xylosyltransferase I
chr21_+_34976600 0.10 ENSDART00000191672
ENSDART00000139635
RNA binding motif protein 11
chr6_+_23935045 0.10 ENSDART00000162993
growth arrest and DNA-damage-inducible, alpha, b
chr5_+_32076109 0.10 ENSDART00000051357
ENSDART00000144510
zinc finger, matrin-type 5
chr24_+_39027481 0.09 ENSDART00000085565
calpain 15
chr16_+_34493987 0.09 ENSDART00000138374
si:ch211-255i3.4
chr17_-_51829310 0.09 ENSDART00000154544
numb homolog (Drosophila)
chr13_-_44630111 0.09 ENSDART00000110092
MAM domain containing glycosylphosphatidylinositol anchor 1
chr9_-_16877456 0.09 ENSDART00000161105
ENSDART00000160869
F-box and leucine-rich repeat protein 3a
chr23_-_19486571 0.09 ENSDART00000009092
family with sequence similarity 208, member Ab
chr6_+_22337081 0.09 ENSDART00000128047
ENSDART00000138930
ubiquinol-cytochrome c reductase core protein 1
chr1_+_34181581 0.09 ENSDART00000146042
eph receptor A6
chr7_-_34256374 0.09 ENSDART00000075176
DIS3 like exosome 3'-5' exoribonuclease
chr16_+_2843428 0.08 ENSDART00000149485
C-type lectin domain family 3, member Ba
chr22_-_718615 0.08 ENSDART00000149320
ADP-ribosylation factor-like 8A
chr17_+_25677458 0.08 ENSDART00000029703
potassium voltage-gated channel, subfamily H (eag-related), member 1a
chr2_-_9744081 0.08 ENSDART00000097732
dishevelled segment polarity protein 3a
chr14_+_904850 0.08 ENSDART00000161847
si:ch73-208h1.1
chr9_+_38043337 0.08 ENSDART00000022574
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr11_+_575665 0.08 ENSDART00000122133
MKRN2 opposite strand, tandem duplicate 1
chr5_+_54497475 0.08 ENSDART00000158149
ENSDART00000163968
ENSDART00000160446
transmembrane protein 203

Network of associatons between targets according to the STRING database.

First level regulatory network of ctcf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.4 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.1 GO:0043388 negative regulation of gliogenesis(GO:0014014) positive regulation of DNA binding(GO:0043388) negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 0.3 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.2 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.0 0.4 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.3 GO:0021592 fourth ventricle development(GO:0021592) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.0 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.3 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.2 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.0 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones