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PRJNA207719: Tissue specific transcriptome profiling

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Results for dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

Z-value: 0.95

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Transcription factors associated with dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

Gene Symbol Gene ID Gene Info
ENSDARG00000017174 distal-less homeobox 2b
ENSDARG00000079964 distal-less homeobox 2a
ENSDARG00000116017 distal-less homeobox 2b
ENSDARG00000011956 distal-less homeobox 4a
ENSDARG00000042291 distal-less homeobox 6a
ENSDARG00000071560 distal-less homeobox 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx4bdr11_v1_chr12_-_5728755_5728755-0.791.1e-01Click!
dlx4adr11_v1_chr3_+_34670076_34670076-0.761.3e-01Click!
dlx6adr11_v1_chr19_+_41419519_414195190.553.4e-01Click!
dlx2adr11_v1_chr9_-_3400727_34007290.098.9e-01Click!
dlx2bdr11_v1_chr1_-_30979707_309797070.019.8e-01Click!

Activity profile of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a motif

Sorted Z-values of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_28731379 1.03 ENSDART00000047378
cortistatin
chr20_-_45060241 0.76 ENSDART00000185227
kelch-like family member 29
chr12_+_24342303 0.75 ENSDART00000111239
neurexin 1a
chr24_-_24849091 0.70 ENSDART00000133649
ENSDART00000038290
corticotropin releasing hormone b
chrM_+_9052 0.68 ENSDART00000093612
ATP synthase 6, mitochondrial
chr17_-_20717845 0.68 ENSDART00000150037
ankyrin 3b
chr20_-_9462433 0.68 ENSDART00000152674
ENSDART00000040557
zgc:101840
chr16_+_5774977 0.68 ENSDART00000134202
cholecystokinin a
chr13_+_38430466 0.66 ENSDART00000132691
adhesion G protein-coupled receptor B3
chr20_-_28800999 0.62 ENSDART00000049462
RAB15, member RAS oncogene family
chr18_+_7204378 0.60 ENSDART00000142905
von Willebrand factor
chr7_+_30787903 0.60 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr4_+_12615836 0.59 ENSDART00000003583
LIM domain only 3
chr6_+_39232245 0.58 ENSDART00000187351
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr5_+_19314574 0.58 ENSDART00000133247
RUN and SH3 domain containing 2
chr25_+_29662411 0.57 ENSDART00000077445
Pim-3 proto-oncogene, serine/threonine kinase
chr10_-_34871737 0.56 ENSDART00000138755
doublecortin-like kinase 1a
chr6_-_54826061 0.54 ENSDART00000149982
troponin I type 1b (skeletal, slow)
chr9_-_21918963 0.53 ENSDART00000090782
LIM domain 7a
chr1_-_44701313 0.52 ENSDART00000193926
si:dkey-28b4.8
chr20_-_29420713 0.51 ENSDART00000147464
ryanodine receptor 3
chr13_-_31435137 0.48 ENSDART00000057441
reticulon 1a
chr15_-_6247775 0.48 ENSDART00000148350
Down syndrome cell adhesion molecule b
chr22_-_7129631 0.47 ENSDART00000171359
acid-sensing (proton-gated) ion channel 1b
chr14_-_30587814 0.47 ENSDART00000144912
ENSDART00000149714
transmembrane protein 265
chr15_+_15856178 0.46 ENSDART00000080338
dual specificity phosphatase 14
chr7_-_28148310 0.45 ENSDART00000044208
LIM domain only 1
chr1_+_16397063 0.44 ENSDART00000159794
mitochondrial calcium uptake family, member 3a
chr1_+_16396870 0.43 ENSDART00000189245
ENSDART00000113266
mitochondrial calcium uptake family, member 3a
chr19_-_7358184 0.43 ENSDART00000092379
oxidation resistance 1b
chr13_-_36911118 0.43 ENSDART00000048739
tripartite motif containing 9
chr6_+_52804267 0.43 ENSDART00000065681
matrilin 4
chrM_+_9735 0.43 ENSDART00000093613
cytochrome c oxidase III, mitochondrial
chr10_+_42690374 0.42 ENSDART00000123496
Rho-related BTB domain containing 2b
chr1_+_11977426 0.42 ENSDART00000103399
tetraspanin 5b
chr17_+_24687338 0.41 ENSDART00000135794
selenoprotein N
chr2_-_33645411 0.40 ENSDART00000114663
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr22_-_11136625 0.40 ENSDART00000016873
ENSDART00000125561
ATPase H+ transporting accessory protein 2
chr14_+_34971554 0.39 ENSDART00000184271
ring finger protein 145a
chr11_-_6974022 0.39 ENSDART00000172851
si:ch211-43f4.1
chr4_+_7391110 0.39 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr20_-_32270866 0.38 ENSDART00000153140
armadillo repeat containing 2
chr20_+_34933183 0.37 ENSDART00000062738
synaptosomal-associated protein, 25a
chr9_-_20372977 0.36 ENSDART00000113418
immunoglobulin superfamily, member 3
chr17_-_21162821 0.36 ENSDART00000157283
abhydrolase domain containing 12
chr17_-_16965809 0.35 ENSDART00000153697
neurexin 3a
chr15_+_31806303 0.35 ENSDART00000155902
furry homolog a (Drosophila)
chr8_-_46894362 0.35 ENSDART00000111124
acyl-CoA thioesterase 7
chr20_+_19238382 0.35 ENSDART00000136757
fibronectin type III domain containing 4a
chr12_+_34953038 0.35 ENSDART00000187022
ENSDART00000123988
ENSDART00000027034
QKI, KH domain containing, RNA binding 2
chr2_-_16380283 0.34 ENSDART00000149992
si:dkey-231j24.3
chr17_-_44247707 0.34 ENSDART00000126097
orthodenticle homeobox 2b
chr10_+_29698467 0.34 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr19_-_32804535 0.34 ENSDART00000175613
ENSDART00000052098
5'-nucleotidase, cytosolic IAa
chr16_+_35661771 0.33 ENSDART00000161393
MAP7 domain containing 1a
chr6_-_41229787 0.32 ENSDART00000065013
synaptoporin
chr15_+_42397125 0.32 ENSDART00000169751
T cell lymphoma invasion and metastasis 1b
chr13_-_44630111 0.31 ENSDART00000110092
MAM domain containing glycosylphosphatidylinositol anchor 1
chr22_-_20166660 0.31 ENSDART00000085913
ENSDART00000188241
BTB (POZ) domain containing 2a
chr3_+_34919810 0.31 ENSDART00000055264
carbonic anhydrase Xb
chr23_+_20563779 0.30 ENSDART00000146008
CaM kinase-like vesicle-associated, like
chr17_-_29119362 0.30 ENSDART00000104204
forkhead box G1a
chr8_-_19051906 0.30 ENSDART00000089024
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr2_+_50608099 0.30 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr17_+_23298928 0.30 ENSDART00000153652
zgc:165461
chr4_+_26629368 0.30 ENSDART00000183575
IQ motif and Sec7 domain 3a
chr6_-_14292307 0.30 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr16_+_13818743 0.30 ENSDART00000090191
folliculin
chr16_-_17197546 0.29 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
glyceraldehyde-3-phosphate dehydrogenase
chr16_+_13818500 0.29 ENSDART00000135245
folliculin
chr4_+_11384891 0.29 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
piccolo presynaptic cytomatrix protein a
chr3_-_46817499 0.28 ENSDART00000013717
ELAV like neuron-specific RNA binding protein 3
chr10_+_3049636 0.27 ENSDART00000081794
ENSDART00000183167
ENSDART00000191634
ENSDART00000183514
Ras protein-specific guanine nucleotide-releasing factor 2a
chr17_-_12389259 0.27 ENSDART00000185724
synaptosomal-associated protein, 25b
chr14_+_23184517 0.27 ENSDART00000181410
ecto-NOX disulfide-thiol exchanger 2
chr18_+_9637744 0.27 ENSDART00000190171
piccolo presynaptic cytomatrix protein b
chr23_-_38497705 0.26 ENSDART00000109493
teashirt zinc finger homeobox 2
chr1_-_50859053 0.26 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr22_+_5176693 0.26 ENSDART00000160927
ceramide synthase 1
chr11_-_37509001 0.26 ENSDART00000109753
bassoon (presynaptic cytomatrix protein) b
chr25_+_29160102 0.26 ENSDART00000162854
pyruvate kinase M1/2b
chr1_+_52929185 0.26 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr16_+_20161805 0.25 ENSDART00000192146
chromosome 16 C2orf66 homolog
chr7_-_25895189 0.24 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr16_+_17389116 0.24 ENSDART00000103750
ENSDART00000173448
family with sequence similarity 131, member Bb
chr10_+_41765616 0.23 ENSDART00000170682
ring finger protein 34b
chr16_-_30434279 0.23 ENSDART00000018504
zgc:77086
chr16_-_12953739 0.23 ENSDART00000103894
calcium channel, voltage-dependent, gamma subunit 8b
chr3_-_34296361 0.23 ENSDART00000181485
ENSDART00000113726
trinucleotide repeat containing 6C1
chr18_-_1185772 0.23 ENSDART00000143245
neuroplastin b
chr6_-_6487876 0.23 ENSDART00000137642
centrosomal protein 170Ab
chr20_+_30445971 0.22 ENSDART00000153150
myelin transcription factor 1-like, a
chr21_-_42100471 0.22 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr16_-_19890303 0.21 ENSDART00000147161
ENSDART00000079159
histone deacetylase 9b
chr9_+_17983463 0.21 ENSDART00000182150
A kinase (PRKA) anchor protein 11
chr20_-_46362606 0.21 ENSDART00000153087
BCL2 modifying factor 2
chr15_-_22074315 0.20 ENSDART00000149830
dopamine receptor D2a
chr22_+_5176255 0.20 ENSDART00000092647
ceramide synthase 1
chr11_+_30057762 0.20 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr19_+_46158078 0.20 ENSDART00000183933
ENSDART00000164055
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr11_-_8126223 0.20 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr18_+_9362455 0.19 ENSDART00000187025
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr15_-_16177603 0.19 ENSDART00000156352
si:ch211-259g3.4
chr21_+_29077509 0.19 ENSDART00000128561
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr16_-_13623928 0.19 ENSDART00000164344
si:dkeyp-69b9.6
chr20_-_27711970 0.18 ENSDART00000139637
zinc finger and BTB domain containing 25
chr18_-_33979693 0.18 ENSDART00000021215
si:ch211-203b20.7
chr6_-_44044385 0.18 ENSDART00000075497
RING1 and YY1 binding protein b
chr4_+_12612145 0.18 ENSDART00000181201
LIM domain only 3
chr4_-_15420452 0.18 ENSDART00000016230
plexin A4
chr10_-_35236949 0.18 ENSDART00000145804
yippee-like 2a
chr5_+_20147830 0.18 ENSDART00000098727
SV2 related protein a
chr21_+_28958471 0.18 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_+_33341640 0.17 ENSDART00000186352
peptide YYa
chr24_+_9412450 0.17 ENSDART00000132724
si:ch211-285f17.1
chr21_-_10488379 0.17 ENSDART00000163878
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr23_-_17484555 0.17 ENSDART00000187181
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr10_+_41765944 0.17 ENSDART00000171484
ring finger protein 34b
chr1_+_45323400 0.17 ENSDART00000148906
ENSDART00000132366
epithelial membrane protein 1
chr19_-_5103141 0.16 ENSDART00000150952
triosephosphate isomerase 1a
chr16_+_35661331 0.16 ENSDART00000161725
MAP7 domain containing 1a
chr16_+_54263921 0.16 ENSDART00000002856
dopamine receptor D2 like
chr11_+_38280454 0.16 ENSDART00000171496
si:dkey-166c18.1
chr12_-_33579873 0.15 ENSDART00000184661
tudor and KH domain containing
chr21_+_34088377 0.15 ENSDART00000170070
myotubularin related protein 1b
chr16_-_47483142 0.15 ENSDART00000147072
collagen triple helix repeat containing 1b
chr19_-_19556778 0.15 ENSDART00000164060
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr2_+_41526904 0.15 ENSDART00000127520
activin A receptor, type 1 like
chr18_+_34478959 0.15 ENSDART00000059394
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr15_-_2184638 0.15 ENSDART00000135460
short stature homeobox 2
chr11_+_33818179 0.14 ENSDART00000109418
speckle-type POZ protein-like b
chr16_-_16120941 0.14 ENSDART00000131227
ankyrin repeat and IBR domain containing 1b
chr1_-_44704261 0.14 ENSDART00000133210
si:dkey-28b4.8
chr16_+_23087326 0.14 ENSDART00000167518
ENSDART00000161087
ephrin-A3b
chr16_-_13623659 0.14 ENSDART00000168978
si:dkeyp-69b9.6
chr13_+_2625150 0.14 ENSDART00000164177
phospholipid phosphatase 4
chr17_-_19963718 0.14 ENSDART00000154251
cholinergic receptor, muscarinic 3a
chr19_-_205104 0.14 ENSDART00000011890
zinc finger and BTB domain containing 22a
chr17_-_14700889 0.14 ENSDART00000179975
protein tyrosine phosphatase type IVA, member 2a
chr21_-_5856050 0.13 ENSDART00000115367

chr5_-_30481263 0.13 ENSDART00000086734
pleckstrin homology-like domain, family B, member 1a
chr11_+_30244356 0.13 ENSDART00000036050
ENSDART00000150080
retinoschisin 1a
chr15_-_20024205 0.12 ENSDART00000161379
autism susceptibility candidate 2b
chr10_+_43039947 0.12 ENSDART00000193434
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr20_-_22476255 0.12 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr7_-_48263516 0.12 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr21_-_15046065 0.11 ENSDART00000178507
matrix metallopeptidase 17a
chr19_-_38830582 0.11 ENSDART00000189966
ENSDART00000183055
adhesion G protein-coupled receptor B2
chr20_-_10120442 0.11 ENSDART00000144970
Meis homeobox 2b
chr21_+_34088110 0.11 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
myotubularin related protein 1b
chr5_-_50781623 0.11 ENSDART00000114950
zgc:194908
chr12_+_33395748 0.11 ENSDART00000129458
fatty acid synthase
chr24_+_38306010 0.11 ENSDART00000143184
myosin binding protein C, fast type b
chr13_+_22295905 0.11 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr18_-_43884044 0.10 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr8_-_38477817 0.10 ENSDART00000075989
inositol polyphosphate-5-phosphatase L
chr9_+_20557793 0.10 ENSDART00000178434
mannosidase, alpha, class 1A, member 2
chr15_-_8665662 0.10 ENSDART00000090675
Rho GTPase activating protein 35a
chr3_+_45365098 0.10 ENSDART00000052746
ENSDART00000156555
ubiquitin-conjugating enzyme E2Ia
chr2_+_4146299 0.09 ENSDART00000173418
mindbomb E3 ubiquitin protein ligase 1
chr21_+_40417152 0.09 ENSDART00000171244
slingshot protein phosphatase 2b
chr18_-_2433011 0.09 ENSDART00000181922
ENSDART00000193276

chr4_+_16885854 0.09 ENSDART00000017726
ethanolamine kinase 1
chr2_+_21229909 0.09 ENSDART00000046127
vasoactive intestinal peptide receptor 1a
chr20_+_13783040 0.09 ENSDART00000115329
ENSDART00000152497
lysophosphatidylglycerol acyltransferase 1
chr2_-_38206034 0.09 ENSDART00000144518
ENSDART00000137395
apoptotic chromatin condensation inducer 1a
chr24_-_39518599 0.09 ENSDART00000145606
ENSDART00000031486
LYR motif containing 1
chr3_-_37571601 0.08 ENSDART00000016407
ADP-ribosylation factor 2a
chr6_+_36807861 0.08 ENSDART00000161708
si:ch73-29l19.1
chr1_-_22512063 0.08 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr6_-_40922971 0.08 ENSDART00000155363
SFI1 centrin binding protein
chr2_+_20793982 0.08 ENSDART00000014785
proteoglycan 4a
chr7_-_12464412 0.08 ENSDART00000178723
ADAMTS-like 3
chr1_+_8534698 0.08 ENSDART00000021504
Smith-Magenis syndrome chromosome region, candidate 8b
chr15_+_36309070 0.08 ENSDART00000157034
geminin coiled-coil domain containing
chr9_-_51436377 0.08 ENSDART00000006612
T-box, brain, 1b
chr15_-_34408777 0.08 ENSDART00000139934
alkylglycerol monooxygenase
chr18_+_1837668 0.08 ENSDART00000164210

chr2_+_38147761 0.07 ENSDART00000135307
spalt-like transcription factor 2
chr2_+_4146606 0.07 ENSDART00000171170
mindbomb E3 ubiquitin protein ligase 1
chr2_-_23004286 0.07 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr25_+_26798673 0.07 ENSDART00000157235
carbonic anhydrase XII
chr10_-_24689280 0.07 ENSDART00000191476
si:ch211-287a12.9
chr15_-_25518084 0.07 ENSDART00000158594
hypoxia-inducible factor 1, alpha subunit, like
chr21_-_11654422 0.06 ENSDART00000081614
ENSDART00000132699
calpastatin
chr22_+_16308450 0.06 ENSDART00000105678
leucine rich repeat containing 39
chr15_+_40792667 0.06 ENSDART00000193186
ENSDART00000184559
FAT atypical cadherin 3a
chr23_+_33963619 0.06 ENSDART00000140666
ENSDART00000084792
pyridoxal phosphate binding protein
chr17_+_28628404 0.06 ENSDART00000032975
ENSDART00000143607
HEAT repeat containing 5a
chr4_+_12612723 0.06 ENSDART00000133767
LIM domain only 3
chr21_+_30355767 0.06 ENSDART00000189948

chr23_+_20518504 0.06 ENSDART00000114246
activity-dependent neuroprotector homeobox b
chr8_+_28452738 0.06 ENSDART00000062706
transmembrane protein 189
chr15_-_38154616 0.06 ENSDART00000099392
immunity-related GTPase family, q2
chr8_-_39822917 0.06 ENSDART00000067843
zgc:162025
chr2_-_7246848 0.05 ENSDART00000146434
zgc:153115
chr1_-_54765262 0.05 ENSDART00000150362
si:ch211-197k17.3
chr8_+_50953776 0.05 ENSDART00000013870
zgc:56596
chr16_+_28578352 0.05 ENSDART00000149306
N-myristoyltransferase 2
chr1_-_21723329 0.05 ENSDART00000137138
si:ch211-134c9.2

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx2a+dlx2b_dlx4a+dlx4b+dlx6a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.7 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.6 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.8 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.4 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.4 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 0.4 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.1 0.3 GO:0007624 ultradian rhythm(GO:0007624)
0.1 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.2 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.3 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.1 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.4 GO:0051481 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.1 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.3 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.7 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0097065 anterior head development(GO:0097065)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:0030814 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 0.0 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.3 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.8 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.9 GO:1990246 uniplex complex(GO:1990246)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0097189 apoptotic body(GO:0097189)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.1 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.5 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.4 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG