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PRJNA207719: Tissue specific transcriptome profiling

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Results for elf3

Z-value: 1.05

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Transcription factors associated with elf3

Gene Symbol Gene ID Gene Info
ENSDARG00000077982 E74-like factor 3 (ets domain transcription factor, epithelial-specific )

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
elf3dr11_v1_chr22_+_661711_6617110.856.5e-02Click!

Activity profile of elf3 motif

Sorted Z-values of elf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_1904419 0.62 ENSDART00000142874
si:ch211-132g1.4
chr20_+_38285671 0.57 ENSDART00000061432
chemokine (C-C motif) ligand 38, duplicate 4
chr22_+_20710434 0.56 ENSDART00000135521
PEAK family member 3
chr23_-_10175898 0.54 ENSDART00000146185
keratin 5
chr15_+_934660 0.54 ENSDART00000154248
si:dkey-77f5.10
chr9_-_33081781 0.51 ENSDART00000165748
zgc:172053
chr11_-_41084358 0.49 ENSDART00000166999
zgc:175088
chr1_+_1896737 0.47 ENSDART00000152442
si:ch211-132g1.6
chr7_+_35075847 0.46 ENSDART00000193469
ENSDART00000037346
chymotrypsinogen B1
chr3_+_29942338 0.44 ENSDART00000158220
interferon-induced protein 35
chr5_-_29531948 0.42 ENSDART00000098360
arrestin domain containing 1a
chr15_-_2652640 0.42 ENSDART00000146094
claudin f
chr13_+_30696286 0.42 ENSDART00000192411
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr17_-_24890843 0.42 ENSDART00000184984
ENSDART00000135569
ENSDART00000193661
UDP-galactose-4-epimerase
chr3_+_24612191 0.41 ENSDART00000190998
zgc:171506
chr1_-_18848955 0.41 ENSDART00000109294
ENSDART00000146410
zgc:195282
chr10_+_38417512 0.41 ENSDART00000112457
SAM domain, SH3 domain and nuclear localisation signals 1b
chr2_-_36918709 0.40 ENSDART00000084876
zgc:153654
chr9_-_54304684 0.40 ENSDART00000109512
interleukin 13
chr20_+_19176959 0.38 ENSDART00000163276
ENSDART00000020099
BLK proto-oncogene, Src family tyrosine kinase
chr15_-_34892664 0.37 ENSDART00000153787
ENSDART00000099721
ring finger protein 183
chr5_-_54712159 0.37 ENSDART00000149207
cyclin B1
chr16_+_38201840 0.36 ENSDART00000044971
myosin IE, b
chr7_-_22981796 0.35 ENSDART00000167565
si:dkey-171c9.3
chr21_-_22673758 0.35 ENSDART00000164910
grass carp reovirus (GCRV)-induced gene 2i
chr5_-_37959874 0.34 ENSDART00000031719
myelin protein zero-like 2b
chr5_+_37087583 0.34 ENSDART00000049900
transgelin 2
chr19_-_12404590 0.33 ENSDART00000103703
finTRIM family, member 56
chr17_-_21368775 0.31 ENSDART00000058027
shootin 1
chr11_+_20899029 0.30 ENSDART00000163029
zgc:162182
chr24_+_37449893 0.30 ENSDART00000164405
NLR family, CARD domain containing 3
chr15_+_1534644 0.30 ENSDART00000130413
structural maintenance of chromosomes 4
chr6_-_8489810 0.29 ENSDART00000124643
RAS protein activator like 3
chr24_+_6353394 0.29 ENSDART00000165118

chr22_+_18886209 0.29 ENSDART00000144402
follistatin-like 3 (secreted glycoprotein)
chr20_-_22798794 0.29 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr6_+_28752943 0.29 ENSDART00000078447
ENSDART00000146574
tumor protein p63 regulated 1
chr21_-_22676323 0.28 ENSDART00000167392
grass carp reovirus (GCRV)-induced gene 2h
chr8_-_52715911 0.27 ENSDART00000168241
tubulin, beta 2b
chr19_-_40199081 0.27 ENSDART00000051970
ENSDART00000151079
granulin 2
chr7_-_18691637 0.26 ENSDART00000183715
si:ch211-119e14.9
chr12_-_44043285 0.26 ENSDART00000163074
si:ch211-182p11.1
chr22_+_1170294 0.26 ENSDART00000159761
ENSDART00000169809
interferon regulatory factor 6
chr8_-_39838660 0.26 ENSDART00000139266
finTRIM family, member 98
chr5_-_29152457 0.26 ENSDART00000078469
NADPH oxidase activator 1
chr20_+_13533544 0.25 ENSDART00000143115
synaptotagmin-like 3
chr13_-_33700461 0.25 ENSDART00000160520
MAD2L1 binding protein
chr6_-_442163 0.25 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
GRB2-related adaptor protein 2b
chr21_+_25198637 0.24 ENSDART00000164972
si:dkey-183i3.6
chr23_+_36087219 0.24 ENSDART00000154825
homeobox C3a
chr1_-_29658721 0.24 ENSDART00000132063
si:dkey-1h24.6
chr6_+_18298444 0.24 ENSDART00000166018
caspase recruitment domain family, member 14
chr2_+_36109002 0.23 ENSDART00000158978
T-cell receptor alpha joining 28
chr20_-_2619316 0.23 ENSDART00000185777
BUB1 mitotic checkpoint serine/threonine kinase
chr20_+_54290356 0.23 ENSDART00000173347
zona pellucida glycoprotein 2, tandem duplicate 2
chr15_-_951118 0.23 ENSDART00000171427
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr11_-_21304452 0.23 ENSDART00000163008
si:dkey-85p17.3
chr6_-_55254786 0.22 ENSDART00000113805
nuclear factor of activated T cells 2b
chr19_+_43341115 0.22 ENSDART00000145846
ENSDART00000102384
sestrin 2
chr20_+_13141408 0.22 ENSDART00000034098
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr25_+_13205878 0.22 ENSDART00000162319
ENSDART00000162283
si:ch211-147m6.2
chr22_-_17652112 0.22 ENSDART00000189205
histocompatibility (minor) HA-1 b
chr19_+_48176745 0.21 ENSDART00000164963
PR domain containing 1b, with ZNF domain
chr16_+_29514473 0.21 ENSDART00000034102
cathepsin S, ortholog 2, tandem duplicate 2
chr1_+_532766 0.21 ENSDART00000179731
ENSDART00000060944
mitochondrial ribosomal protein L39
chr19_+_43341424 0.21 ENSDART00000134815
sestrin 2
chr20_-_13625588 0.21 ENSDART00000078893
synaptotagmin-like 3
chr22_-_17652914 0.21 ENSDART00000138483
si:ch73-243b8.4
chr7_+_29509255 0.21 ENSDART00000076172
si:dkey-182o15.5
chr5_-_26834511 0.20 ENSDART00000136713
ENSDART00000192932
ENSDART00000113246
si:ch211-102c2.4
chr24_+_39990695 0.20 ENSDART00000040281

chr4_-_58964138 0.20 ENSDART00000150259
si:ch211-64i20.3
chr4_-_22310956 0.20 ENSDART00000162585
hematopoietic cell-specific Lyn substrate 1
chr1_-_8020589 0.20 ENSDART00000143881
si:dkeyp-9d4.2
chr3_+_49576662 0.19 ENSDART00000162275

chr13_+_31070181 0.19 ENSDART00000110560
ENSDART00000146088
si:ch211-223a10.1
chr14_-_11529311 0.19 ENSDART00000127208
si:ch211-153b23.7
chr9_+_2499627 0.19 ENSDART00000160782
WAS/WASL interacting protein family, member 1a
chr13_-_21672131 0.18 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr4_-_4261673 0.18 ENSDART00000150694
CD9 molecule b
chr20_+_34770197 0.18 ENSDART00000018304
minichromosome maintenance complex component 3
chr1_-_59252973 0.18 ENSDART00000167061
si:ch1073-286c18.5
chr19_+_4038589 0.18 ENSDART00000169271
bloodthirsty-related gene family, member 23
chr11_+_8129536 0.18 ENSDART00000158112
ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr15_-_28677725 0.18 ENSDART00000060255
bleomycin hydrolase
chr7_+_22981909 0.18 ENSDART00000122449
cyclin B3
chr5_+_32141790 0.17 ENSDART00000041504
tescalcin b
chr7_+_26545502 0.17 ENSDART00000140528
tyrosine kinase, non-receptor, 1
chr1_-_11104805 0.17 ENSDART00000147648
kinetochore scaffold 1
chr15_+_15415623 0.16 ENSDART00000127436
zgc:92630
chr21_+_6114305 0.16 ENSDART00000141607
folylpolyglutamate synthase
chr4_+_7822773 0.16 ENSDART00000171391
si:ch1073-67j19.2
chr4_-_992063 0.16 ENSDART00000181630
ENSDART00000183898
ENSDART00000160902
N-acetylgalactosaminidase, alpha
chr21_+_35296246 0.16 ENSDART00000076750
interleukin 12B, b
chr24_-_6038025 0.15 ENSDART00000077819
ENSDART00000139216
finTRIM family, member 61
chr8_-_36399884 0.15 ENSDART00000108538
si:zfos-2070c2.3
chr2_-_59205393 0.15 ENSDART00000056417
ENSDART00000182452
ENSDART00000141876
finTRIM family, member 30
chr1_-_59407322 0.15 ENSDART00000161661
si:ch211-188p14.5
chr16_-_15387459 0.15 ENSDART00000053754
hyaluronan synthase 2
chr4_-_5795309 0.15 ENSDART00000039987
phosphoglucomutase 3
chr1_-_21881818 0.15 ENSDART00000047728
maternal embryonic leucine zipper kinase
chr2_-_59303338 0.15 ENSDART00000100987
ENSDART00000140840
finTRIM family, member 35
chr8_-_42594380 0.15 ENSDART00000140126
ENSDART00000135238
ENSDART00000192764
docking protein 2
chr9_+_3153717 0.15 ENSDART00000191958
si:zfos-979f1.2
chr3_-_10706846 0.14 ENSDART00000157260
si:ch73-1f23.1
chr22_-_24967348 0.14 ENSDART00000153490
ENSDART00000084871
family with sequence similarity 20, member C like
chr14_-_897874 0.14 ENSDART00000167395
regulator of G protein signaling 14a
chr10_-_1523253 0.14 ENSDART00000179510
ENSDART00000176548
ENSDART00000180368
ENSDART00000185270
WD repeat domain 70
chr7_+_22981441 0.14 ENSDART00000182887
cyclin B3
chr5_+_24245682 0.14 ENSDART00000049003
ATPase H+ transporting V1 subunit Aa
chr13_-_34858500 0.13 ENSDART00000184843
serine palmitoyltransferase, long chain base subunit 3
chr20_-_18382708 0.13 ENSDART00000170864
ENSDART00000166762
ENSDART00000191333
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr13_-_35908275 0.13 ENSDART00000013961
MYCL proto-oncogene, bHLH transcription factor a
chr4_-_7869731 0.13 ENSDART00000067339
minichromosome maintenance 10 replication initiation factor
chr9_+_48108174 0.13 ENSDART00000077260
chemokine (C-X-C motif) receptor 2
chr15_+_3808996 0.13 ENSDART00000110227
ring finger protein 14
chr8_+_22438398 0.13 ENSDART00000135145
zgc:153759
chr23_+_19790962 0.13 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr7_+_19762595 0.13 ENSDART00000130347
si:dkey-9k7.3
chr11_-_21303946 0.12 ENSDART00000185786
si:dkey-85p17.3
chr9_+_3153466 0.12 ENSDART00000135619
si:zfos-979f1.2
chr8_-_7093507 0.12 ENSDART00000045669
si:dkey-222n6.2
chr22_-_30973791 0.12 ENSDART00000104728
ssu-2 homolog, tandem duplicate 2
chr13_-_35907768 0.12 ENSDART00000147522
MYCL proto-oncogene, bHLH transcription factor a
chr3_+_43826018 0.12 ENSDART00000166197
ENSDART00000165145
lipopolysaccharide-induced TNF factor
chr24_-_13349464 0.12 ENSDART00000134482
ENSDART00000139212
telomeric repeat binding factor (NIMA-interacting) 1
chr10_-_41450367 0.12 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr8_+_25342896 0.12 ENSDART00000129032

chr14_+_41318412 0.12 ENSDART00000064614
XK, Kell blood group complex subunit-related, X-linked
chr13_+_1089942 0.12 ENSDART00000054322
cannabinoid receptor interacting protein 1b
chr22_+_2598998 0.12 ENSDART00000176665

chr23_-_19103855 0.12 ENSDART00000016901
par-6 partitioning defective 6 homolog beta (C. elegans)
chr23_+_32101361 0.12 ENSDART00000138849
zgc:56699
chr14_+_6287871 0.12 ENSDART00000105344
TBC1 domain family, member 2
chr2_+_36646451 0.12 ENSDART00000039174
kelch-like family member 6
chr1_+_33558555 0.12 ENSDART00000018472
charged multivesicular body protein 2Bb
chr14_+_41318604 0.11 ENSDART00000167042
XK, Kell blood group complex subunit-related, X-linked
chr4_+_70414733 0.11 ENSDART00000162778
si:dkey-190j3.3
chr1_-_24349759 0.11 ENSDART00000142740
ENSDART00000177989
LPS-responsive vesicle trafficking, beach and anchor containing
chr21_+_14511685 0.11 ENSDART00000102099

chr21_-_45073764 0.11 ENSDART00000181390
ENSDART00000063714
Rap guanine nucleotide exchange factor (GEF) 6
chr24_-_38113208 0.11 ENSDART00000079003
c-reactive protein, pentraxin-related
chr8_+_20157798 0.11 ENSDART00000124809
acyl-CoA synthetase bubblegum family member 2
chr9_+_34952203 0.11 ENSDART00000121828
ENSDART00000142347
transcription factor Dp-1, a
chr5_-_23464970 0.11 ENSDART00000141028
si:dkeyp-20g2.1
chr14_+_20911310 0.11 ENSDART00000160318
lysozyme g-like 2
chr9_+_3282369 0.11 ENSDART00000044128
histone acetyltransferase 1
chr5_+_42136359 0.11 ENSDART00000083731
transient receptor potential cation channel, subfamily V, member 1
chr3_-_36210344 0.11 ENSDART00000025326
casein kinase 1, delta a
chr23_+_32101202 0.11 ENSDART00000000992
zgc:56699
chr15_-_2734560 0.11 ENSDART00000153853
protein phosphatase 5, catalytic subunit
chr3_+_19245804 0.11 ENSDART00000134514
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr21_-_40173821 0.11 ENSDART00000180667
solute carrier organic anion transporter family, member 2B1
chr22_+_16022211 0.10 ENSDART00000062618
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr7_-_24204665 0.10 ENSDART00000167141
guanosine monophosphate reductase 2
chr19_-_3741602 0.10 ENSDART00000170301
bloodthirsty-related gene family, member 22
chr12_-_33558879 0.10 ENSDART00000161167
mbt domain containing 1
chr16_-_17300030 0.10 ENSDART00000149267
Kell blood group, metallo-endopeptidase
chr12_-_33558727 0.10 ENSDART00000086087
mbt domain containing 1
chr10_+_42169982 0.10 ENSDART00000190905

chr5_+_40835601 0.10 ENSDART00000147767
si:dkey-3h3.3
chr1_+_12301913 0.10 ENSDART00000165733
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr23_-_4705110 0.10 ENSDART00000144536
ENSDART00000129050
ENSDART00000136399
CCHC-type zinc finger, nucleic acid binding protein a
chr3_+_57997980 0.10 ENSDART00000168477
ENSDART00000193840
pyrroline-5-carboxylate reductase 1a
chr4_+_35590588 0.10 ENSDART00000183582
si:dkeyp-4c4.2
chr5_-_29534748 0.10 ENSDART00000159587

chr4_-_12723585 0.10 ENSDART00000185639
microsomal glutathione S-transferase 1.2
chr2_-_59265521 0.10 ENSDART00000146341
ENSDART00000097799
finTRIM family, member 33
chr17_+_44441042 0.09 ENSDART00000142123
adaptor-related protein complex 5, mu 1 subunit
chr1_-_34450784 0.09 ENSDART00000140515
LIM domain 7b
chr2_-_59376399 0.09 ENSDART00000137134
finTRIM family, member 38
chr11_+_13423776 0.09 ENSDART00000102553
homer scaffolding protein 3b
chr21_+_21244046 0.09 ENSDART00000058306
ENSDART00000189665
ENSDART00000131890
leukemia inhibitory factor receptor alpha b
chr10_-_105100 0.09 ENSDART00000145716
tetratricopeptide repeat domain 3
chr4_+_37936839 0.09 ENSDART00000164505
si:dkeyp-82b4.2
chr15_+_14854666 0.09 ENSDART00000163066
diablo, IAP-binding mitochondrial protein a
chr21_+_6197223 0.09 ENSDART00000147716
si:dkey-93m18.3
chr5_+_37406358 0.09 ENSDART00000162811
kelch-like family member 13
chr2_-_59327299 0.09 ENSDART00000133734
finTRIM family, member 36
chr1_+_11659861 0.08 ENSDART00000054787

chr7_+_73295890 0.08 ENSDART00000174331
ENSDART00000174250

chr24_-_13349802 0.08 ENSDART00000164729
telomeric repeat binding factor (NIMA-interacting) 1
chr16_-_40426837 0.08 ENSDART00000193690
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr19_+_47476908 0.08 ENSDART00000157886
zgc:114119
chr25_-_34632050 0.08 ENSDART00000170671
multiple EGF-like-domains 8
chr25_+_34749812 0.08 ENSDART00000185712
WW domain containing E3 ubiquitin protein ligase 2
chr15_-_35100858 0.08 ENSDART00000099677
biogenesis of lysosomal organelles complex-1, subunit 3
chr17_-_44440832 0.08 ENSDART00000148786
exocyst complex component 5
chr16_+_43368572 0.08 ENSDART00000032778
ENSDART00000193897
ring finger protein 144B
chr11_+_36665359 0.08 ENSDART00000166144
si:ch211-11c3.9
chr3_+_52737565 0.08 ENSDART00000108639
GEM interacting protein
chr2_-_24068848 0.08 ENSDART00000145526
solute carrier family 12 (potassium/chloride transporter), member 7a
chr25_+_5015019 0.07 ENSDART00000127600
histone deacetylase 10
chr8_-_13029297 0.07 ENSDART00000144305
DENN/MADD domain containing 2Da
chr13_+_10023256 0.07 ENSDART00000110035
S1 RNA binding domain 1
chr24_+_20916751 0.07 ENSDART00000043193
cystatin 14a, tandem duplicate 1
chr7_-_19915414 0.07 ENSDART00000144180
zgc:110591
chr2_+_36721357 0.07 ENSDART00000019063
programmed cell death 10b
chr1_+_57774454 0.07 ENSDART00000152507
si:dkey-1c7.2
chr1_+_58400409 0.07 ENSDART00000111526
si:ch73-59p9.2

Network of associatons between targets according to the STRING database.

First level regulatory network of elf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.1 0.4 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.3 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.1 0.4 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.1 0.2 GO:0045226 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.0 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.3 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.2 GO:0072422 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0035046 pronuclear migration(GO:0035046)
0.0 0.2 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:2000403 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.4 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.7 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.0 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.5 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 0.2 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0051916 C-X-C chemokine receptor activity(GO:0016494) granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0009384 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage