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PRJNA207719: Tissue specific transcriptome profiling

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Results for emx2+emx3

Z-value: 0.99

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Transcription factors associated with emx2+emx3

Gene Symbol Gene ID Gene Info
ENSDARG00000020417 empty spiracles homeobox 3
ENSDARG00000039701 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
emx2dr11_v1_chr13_+_19322686_19322686-0.903.9e-02Click!
emx3dr11_v1_chr14_-_26377044_26377044-0.751.5e-01Click!

Activity profile of emx2+emx3 motif

Sorted Z-values of emx2+emx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_2815021 0.91 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr5_+_35458190 0.90 ENSDART00000051313
fructose-1,6-bisphosphatase 1b
chr4_+_25654686 0.78 ENSDART00000100714
acyl-CoA thioesterase 16
chr2_+_41926707 0.71 ENSDART00000023208
zgc:110183
chr20_-_40755614 0.61 ENSDART00000061247
connexin 32.3
chr6_+_49926115 0.60 ENSDART00000018523
adenosylhomocysteinase
chr20_+_54309148 0.55 ENSDART00000099360
zona pellucida glycoprotein 2, tandem duplicate 1
chr25_+_22320738 0.54 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr1_-_18811517 0.54 ENSDART00000142026
si:dkey-167i21.2
chr8_-_23780334 0.54 ENSDART00000145179
ENSDART00000145894
zgc:195245
chr20_+_54299419 0.53 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
chr5_-_42083363 0.52 ENSDART00000162596
chemokine (C-X-C motif) ligand 11, duplicate 5
chr20_-_43663494 0.50 ENSDART00000144564

chr8_-_2616326 0.50 ENSDART00000027214
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr15_+_36457888 0.49 ENSDART00000155100
si:dkey-262k9.2
chr4_+_7817996 0.47 ENSDART00000166809
si:ch1073-67j19.1
chr22_-_17729778 0.46 ENSDART00000192132
si:ch73-63e15.2
chr5_-_42082730 0.44 ENSDART00000135625
chemokine (C-X-C motif) ligand 11, duplicate 5
chr19_-_10330778 0.44 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
coiled-coil domain containing 106b
chr20_+_54304800 0.44 ENSDART00000121661
zona pellucida glycoprotein 2, tandem duplicate 6
chr3_-_59297532 0.44 ENSDART00000187991

chr11_-_6452444 0.43 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
La ribonucleoprotein domain family, member 6b
chr23_-_44965582 0.42 ENSDART00000163367
transferrin receptor 2
chr5_+_35458346 0.42 ENSDART00000141239
ER lipid raft associated 2
chr12_+_20587179 0.41 ENSDART00000170127
arylsulfatase G
chr16_-_50897887 0.39 ENSDART00000156985
si:ch73-90p23.1
chr19_-_20403845 0.39 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
deleted in azoospermia-like
chr23_+_32101202 0.37 ENSDART00000000992
zgc:56699
chr23_+_26026383 0.37 ENSDART00000141553
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr23_+_41679586 0.37 ENSDART00000067662

chr3_+_3681116 0.35 ENSDART00000109618
ADP-ribosyltransferase 4 (Dombrock blood group)
chr2_+_19522082 0.35 ENSDART00000146098
Pim proto-oncogene, serine/threonine kinase, related 49
chr10_-_44560165 0.34 ENSDART00000181217
ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr21_+_18997511 0.34 ENSDART00000145591
ribosomal protein L17
chr6_+_612594 0.34 ENSDART00000150903
kynureninase
chr15_-_14625373 0.34 ENSDART00000171841
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr9_+_38314466 0.33 ENSDART00000048753
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr14_+_29941445 0.33 ENSDART00000181761
family with sequence similarity 149 member A
chr13_-_31622195 0.33 ENSDART00000057432
SIX homeobox 1a
chr10_+_21867307 0.33 ENSDART00000126629
cerebellin 17
chr15_-_40157331 0.32 ENSDART00000187958
si:ch211-281l24.3
chr18_+_5490668 0.32 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr16_-_38118003 0.32 ENSDART00000058667
si:dkey-23o4.6
chr6_+_25257728 0.32 ENSDART00000162581
kynurenine aminotransferase 3
chr7_+_24573721 0.31 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr7_+_4694924 0.31 ENSDART00000144873
si:ch211-225k7.3
chr22_-_31060579 0.31 ENSDART00000182376
cullin-associated and neddylation-dissociated 2 (putative)
chr3_+_54553931 0.30 ENSDART00000029387
peter pan homolog (Drosophila)
chr1_-_513762 0.30 ENSDART00000148162
ENSDART00000144606
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr2_-_17392799 0.30 ENSDART00000136470
ENSDART00000141188
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr15_+_34934568 0.30 ENSDART00000165210
zgc:66024
chr15_-_40157513 0.29 ENSDART00000184014
si:ch211-281l24.3
chr23_+_21405201 0.29 ENSDART00000144409
intermediate filament family orphan 2a
chr21_+_43702016 0.29 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr25_+_14092871 0.29 ENSDART00000067239
guanylate cyclase activator 1g
chr10_+_24468922 0.29 ENSDART00000008248
ENSDART00000183510
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_-_20403507 0.29 ENSDART00000052603
ENSDART00000137590
deleted in azoospermia-like
chr7_+_59020972 0.29 ENSDART00000157873
3-hydroxyacyl-CoA dehydratase 1
chr6_+_39905021 0.28 ENSDART00000064904
endonuclease, polyU-specific
chr12_-_25294769 0.28 ENSDART00000153306
hydroxycarboxylic acid receptor 1-4
chr7_+_4694762 0.28 ENSDART00000132862
si:ch211-225k7.3
chr7_+_4474880 0.27 ENSDART00000143528
si:dkey-83f18.14
chr2_+_19633493 0.27 ENSDART00000147989
Pim proto-oncogene, serine/threonine kinase, related 54
chr5_+_44944778 0.26 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
doublesex and mab-3 related transcription factor 1
chr25_+_31276842 0.26 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr11_+_40812590 0.26 ENSDART00000186690
ERBB receptor feedback inhibitor 1a
chr25_+_31277415 0.26 ENSDART00000036275
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr15_+_17728180 0.26 ENSDART00000081105
si:ch211-213d14.1
chr17_+_8799661 0.26 ENSDART00000105326
tonsoku-like, DNA repair protein
chr9_-_390874 0.26 ENSDART00000165324
si:dkey-11f4.7
chr15_-_40157165 0.25 ENSDART00000192991
si:ch211-281l24.3
chr23_-_19686791 0.25 ENSDART00000161973
zgc:193598
chr19_+_43780970 0.25 ENSDART00000063870
ribosomal protein L11
chr18_-_48547564 0.25 ENSDART00000138607
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr22_+_19366866 0.25 ENSDART00000137301
si:dkey-21e2.12
chr9_-_5318873 0.25 ENSDART00000129308
activin A receptor type 1C
chr20_-_33556983 0.25 ENSDART00000168798
rho-associated, coiled-coil containing protein kinase 2b, like
chr5_+_6954162 0.24 ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr16_-_31622777 0.24 ENSDART00000137311
ENSDART00000002930
PHD finger protein 20 like 1
chr2_+_30182431 0.24 ENSDART00000004903
retinol dehydrogenase 10b
chr11_+_11200550 0.24 ENSDART00000181339
ENSDART00000187116
myomesin 2a
chr24_+_42004640 0.24 ENSDART00000171380
DNA topoisomerase I mitochondrial
chr2_+_14992879 0.24 ENSDART00000137546
Pim proto-oncogene, serine/threonine kinase, related 55
chr1_-_9195629 0.24 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr7_-_66868543 0.24 ENSDART00000149680
adenosine monophosphate deaminase 3a
chr10_+_34010494 0.24 ENSDART00000186836
ENSDART00000114703
klotho
chr3_+_23029484 0.24 ENSDART00000187900
N-acetylglutamate synthase
chr1_-_5455498 0.23 ENSDART00000040368
ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr18_-_977075 0.23 ENSDART00000032392
dihydrodiol dehydrogenase (dimeric), like
chr2_+_19578446 0.23 ENSDART00000164758
Pim proto-oncogene, serine/threonine kinase, related 50
chr5_-_25733745 0.23 ENSDART00000051566
zgc:101016
chr20_-_5291012 0.23 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr25_+_3358701 0.23 ENSDART00000104877
coiled-coil-helix-coiled-coil-helix domain containing 3b
chr2_+_37227011 0.23 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr2_+_20406399 0.23 ENSDART00000006817
ENSDART00000137848
palmdelphin a
chr20_+_25586099 0.23 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr3_+_32118670 0.23 ENSDART00000055287
ENSDART00000111688
zgc:109934
chr9_-_22147567 0.22 ENSDART00000110941
crystallin, gamma M2d14
chr18_-_6766354 0.22 ENSDART00000132611
adrenomedullin 2b
chr11_-_10456553 0.22 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
epithelial cell transforming 2
chr10_-_34916208 0.22 ENSDART00000187371
cyclin A1
chr13_+_646700 0.22 ENSDART00000006892
tumor protein p53 binding protein, 2a
chr22_-_30770751 0.22 ENSDART00000172115

chr10_-_17550239 0.22 ENSDART00000057513
spindle and kinetochore associated complex subunit 1
chr19_-_20403318 0.22 ENSDART00000136826
deleted in azoospermia-like
chr22_-_22337382 0.22 ENSDART00000144684
si:ch211-129c21.1
chr12_-_29305533 0.22 ENSDART00000189410
SH2 domain containing 4Bb
chr11_-_10456387 0.22 ENSDART00000011087
ENSDART00000081827
epithelial cell transforming 2
chr19_-_2822372 0.21 ENSDART00000109130
ENSDART00000122385
RecQ helicase-like 4
chr25_+_13157165 0.21 ENSDART00000155653
si:dkeyp-50b9.1
chr19_-_47323267 0.21 ENSDART00000190077

chr6_+_6828167 0.21 ENSDART00000181284
si:ch211-85n16.4
chr15_-_46779934 0.21 ENSDART00000085136
chloride channel 2c
chr25_-_12937727 0.21 ENSDART00000172643
chemokine (C-C motif) ligand 39, duplicate 6
chr9_+_29548195 0.21 ENSDART00000176057
ring finger protein 17
chr21_-_1644414 0.21 ENSDART00000105736
ENSDART00000124904
zgc:152948
chr17_-_7496341 0.21 ENSDART00000186907
si:ch211-278p9.3
chr10_-_35257458 0.20 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr4_+_28997595 0.20 ENSDART00000133357
si:dkey-13e3.1
chr12_+_9250107 0.20 ENSDART00000152249
Pim proto-oncogene, serine/threonine kinase, related 46
chr7_+_4922104 0.20 ENSDART00000135154
si:dkey-28d5.11
chr1_+_44127292 0.20 ENSDART00000160542
calcium binding protein 2a
chr8_+_53080515 0.20 ENSDART00000143009
WD repeat domain 46
chr13_+_24756486 0.20 ENSDART00000137074
collagen, type XVII, alpha 1b
chr3_+_23029934 0.20 ENSDART00000110343
N-acetylglutamate synthase
chr24_+_19415124 0.19 ENSDART00000186931
sulfatase 1
chr2_+_19578079 0.19 ENSDART00000144413
Pim proto-oncogene, serine/threonine kinase, related 50
chr20_-_9658405 0.19 ENSDART00000023809
nidogen 2b (osteonidogen)
chr25_-_21816269 0.19 ENSDART00000152014
zgc:158222
chr1_-_9629705 0.19 ENSDART00000166601
ENSDART00000164079
UDP glucuronosyltransferase 5 family, polypeptide B5
chr9_+_48761455 0.19 ENSDART00000139631
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr1_+_40158146 0.19 ENSDART00000145694
si:ch211-113e8.9
chr8_-_53044300 0.18 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr2_-_19520690 0.18 ENSDART00000133559
Pim proto-oncogene, serine/threonine kinase, related 52
chr2_-_17393216 0.18 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr5_-_24238733 0.18 ENSDART00000138170
phospholipid scramblase 3a
chr14_+_29941266 0.18 ENSDART00000112757
family with sequence similarity 149 member A
chr12_+_45238292 0.18 ENSDART00000057983
mitochondrial ribosomal protein L38
chr3_-_42981739 0.18 ENSDART00000167844
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr17_-_7473890 0.18 ENSDART00000192910
si:ch211-278p9.2
chr23_-_23179417 0.18 ENSDART00000122945
ENSDART00000091662
NOC2-like nucleolar associated transcriptional repressor
chr13_+_7442023 0.18 ENSDART00000080975
tumor necrosis factor, alpha-induced protein 2b
chr4_+_28998230 0.18 ENSDART00000183828
si:dkey-13e3.1
chr12_-_17712393 0.18 ENSDART00000143534
ENSDART00000010144
parvalbumin 2
chr4_-_72513569 0.18 ENSDART00000174130

chr18_+_33521609 0.18 ENSDART00000147592
vomeronasal 2 receptor, h7
chr7_-_2285499 0.18 ENSDART00000182211
si:dkey-187j14.6
chr16_+_32736588 0.17 ENSDART00000075191
ENSDART00000168358
zgc:172323
chr13_+_6219551 0.17 ENSDART00000025910
adipocyte plasma membrane associated protein
chr12_+_30653047 0.17 ENSDART00000148562
thrombospondin 2b
chr25_-_13188678 0.17 ENSDART00000125754
si:ch211-147m6.1
chr9_+_28598577 0.17 ENSDART00000142623
ENSDART00000135947
si:ch73-7i4.1
chr22_+_17261801 0.17 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr17_+_389218 0.17 ENSDART00000162898
si:rp71-62i8.1
chr20_+_98179 0.17 ENSDART00000022725
si:ch1073-155h21.1
chr20_-_38801981 0.17 ENSDART00000125333
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr18_+_15616167 0.17 ENSDART00000080454
solute carrier family 17 (vesicular glutamate transporter), member 8
chr12_+_34896956 0.17 ENSDART00000055415
peripherin 2a (retinal degeneration, slow)
chr24_+_39105051 0.17 ENSDART00000115297
MSS51 mitochondrial translational activator
chr13_+_40686133 0.17 ENSDART00000146112
Hermansky-Pudlak syndrome 1
chr7_+_4648398 0.17 ENSDART00000148099
si:dkey-83f18.3
chr3_+_23731109 0.16 ENSDART00000131410
homeobox B3a
chr9_-_22355391 0.16 ENSDART00000009115
crystallin, gamma M3
chr10_+_31248036 0.16 ENSDART00000193574
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr23_-_1660708 0.16 ENSDART00000175138

chr7_-_2285314 0.16 ENSDART00000153614
si:dkey-187j14.6
chr13_-_15082024 0.16 ENSDART00000157482
sideroflexin 5a
chr11_+_30091155 0.16 ENSDART00000158691
si:ch211-161f7.2
chr2_-_17235891 0.16 ENSDART00000144251
artemin b
chr6_-_39649504 0.16 ENSDART00000179960
ENSDART00000190951
La ribonucleoprotein domain family, member 4Ab
chr22_+_5532003 0.16 ENSDART00000106174
si:ch73-256j6.2
chr11_-_34166960 0.16 ENSDART00000181571
ATPase 13A3
chr21_+_10739846 0.16 ENSDART00000084011
complexin 4a
chr7_+_9008372 0.16 ENSDART00000144897

chr20_+_42881104 0.16 ENSDART00000131338
Pim proto-oncogene, serine/threonine kinase, related 110
chr2_-_19576640 0.16 ENSDART00000141021
Pim proto-oncogene, serine/threonine kinase, related 51
chr18_-_40708537 0.16 ENSDART00000077577
si:ch211-132b12.8
chr2_+_9990491 0.16 ENSDART00000011906
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr23_-_19140781 0.16 ENSDART00000143580
si:ch73-381f5.2
chr16_+_32152612 0.16 ENSDART00000008880
G protein-coupled receptor, class C, group 6, member A
chr11_-_38533505 0.16 ENSDART00000113894
solute carrier family 45, member 3
chr24_+_26329018 0.16 ENSDART00000145752
myoneurin
chr11_+_31324335 0.15 ENSDART00000088093
signal-induced proliferation-associated 1 like 2
chr22_+_31207799 0.15 ENSDART00000133267
glutamate receptor interacting protein 2b
chr7_+_4682458 0.15 ENSDART00000139271
si:ch211-225k7.2
chr21_-_44081540 0.15 ENSDART00000130833

chr18_-_5527050 0.15 ENSDART00000145400
ENSDART00000132498
ENSDART00000146209
zgc:153317
chr18_-_25279323 0.15 ENSDART00000191547
perilipin 1
chr5_+_72194444 0.15 ENSDART00000165436
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr7_+_20512419 0.15 ENSDART00000173907
si:dkey-19b23.14
chr11_-_6877973 0.15 ENSDART00000160271
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr6_-_52788213 0.15 ENSDART00000179880
recombination signal binding protein for immunoglobulin kappa J region-like
chr11_+_42474694 0.15 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
chr15_-_2493771 0.15 ENSDART00000184906
sialidase 4
chr23_+_32039386 0.15 ENSDART00000133801
myosin light chain kinase 2
chr23_+_4709607 0.15 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr2_-_31833347 0.14 ENSDART00000109460
nucleolar protein 7
chr17_+_12285285 0.14 ENSDART00000154336
Pim proto-oncogene, serine/threonine kinase, related 174
chr13_+_733027 0.14 ENSDART00000149547
neurexin 1b
chr14_-_26482096 0.14 ENSDART00000187280
SMAD family member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of emx2+emx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005985 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.2 0.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.9 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.3 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.5 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.4 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.3 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.1 0.3 GO:0030238 male sex determination(GO:0030238)
0.1 0.2 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.1 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.2 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.1 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100)
0.0 0.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.2 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.4 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.3 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.4 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 1.1 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.4 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.1 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.3 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.1 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0007568 aging(GO:0007568)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 0.1 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.1 GO:0072584 optomotor response(GO:0071632) caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.5 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.0 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.3 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.3 0.9 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.5 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 0.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.9 GO:0008494 translation activator activity(GO:0008494)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 0.3 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.2 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.0 0.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.0 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.1 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP