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PRJNA207719: Tissue specific transcriptome profiling

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Results for fosb+fosl2+si:ch211-153j24.3

Z-value: 1.29

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Transcription factors associated with fosb+fosl2+si:ch211-153j24.3

Gene Symbol Gene ID Gene Info
ENSDARG00000040623 fos-like antigen 2
ENSDARG00000055751 FBJ murine osteosarcoma viral oncogene homolog B
ENSDARG00000068428 si_ch211-153j24.3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:ch211-153j24.3dr11_v1_chr20_+_46544052_46544052-0.976.7e-03Click!
fosbdr11_v1_chr18_+_36770166_36770166-0.894.2e-02Click!
fosl2dr11_v1_chr17_+_41302660_41302660-0.761.4e-01Click!

Activity profile of fosb+fosl2+si:ch211-153j24.3 motif

Sorted Z-values of fosb+fosl2+si:ch211-153j24.3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_18253111 1.01 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr25_-_13408760 0.96 ENSDART00000154445
GINS complex subunit 3
chr19_+_48359259 0.91 ENSDART00000167353
shugoshin 1
chr25_-_22187397 0.82 ENSDART00000123211
ENSDART00000139110
plakophilin 3a
chr12_+_25945560 0.80 ENSDART00000109799
multimerin 2b
chr13_+_24280380 0.75 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr21_-_2415808 0.72 ENSDART00000171179
si:ch211-241b2.5
chr6_-_35439406 0.70 ENSDART00000073784
regulator of G protein signaling 5a
chr16_-_22930925 0.67 ENSDART00000133819
si:dkey-246i14.3
chr25_+_13191391 0.67 ENSDART00000109937
si:ch211-147m6.2
chr16_+_23403602 0.64 ENSDART00000159848
S100 calcium binding protein W
chr6_+_51713076 0.63 ENSDART00000146281
RIPOR family member 3
chr17_-_53359028 0.57 ENSDART00000185218

chr19_+_15441022 0.57 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr13_-_37122217 0.57 ENSDART00000133242
spectrin repeat containing, nuclear envelope 2b
chr19_+_4061699 0.56 ENSDART00000158309
ENSDART00000166512
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr15_+_963292 0.56 ENSDART00000156586
arachidonate 5-lipoxygenase b, tandem duplicate 2
chr14_-_11456724 0.54 ENSDART00000110424
si:ch211-153b23.4
chr18_-_5595546 0.53 ENSDART00000191825
cytochrome P450, family 1, subfamily A
chr5_+_24089334 0.52 ENSDART00000183748
tumor protein p53
chr23_+_4324625 0.52 ENSDART00000146302
ENSDART00000136792
ENSDART00000135027
ENSDART00000179819
serum/glucocorticoid regulated kinase 2a
chr5_+_9037650 0.51 ENSDART00000158226
si:ch211-155m12.1
chr5_-_25582721 0.51 ENSDART00000123986
annexin A1a
chr22_-_15593824 0.51 ENSDART00000123125
tropomyosin 4a
chr7_-_32981559 0.49 ENSDART00000175614
plakophilin 3b
chr4_+_77971104 0.49 ENSDART00000188609
zgc:113921
chr4_+_77735212 0.47 ENSDART00000160716
si:dkey-238k10.1
chr13_-_15982707 0.46 ENSDART00000186911
ENSDART00000181072
IKAROS family zinc finger 1 (Ikaros)
chr25_+_13191615 0.46 ENSDART00000168849
si:ch211-147m6.2
chr7_-_44963154 0.45 ENSDART00000073735
Ras-related associated with diabetes
chr20_+_26880668 0.44 ENSDART00000077769
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr15_-_38129845 0.43 ENSDART00000057095
si:dkey-24p1.1
chr21_+_5636008 0.42 ENSDART00000158385
shroom family member 3
chr10_-_44560165 0.42 ENSDART00000181217
ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr18_-_45617146 0.42 ENSDART00000146543
wilms tumor 1b
chr18_+_50650512 0.42 ENSDART00000161022
si:dkey-151j17.4
chr1_+_14253118 0.42 ENSDART00000161996
chemokine (C-X-C motif) ligand 8a
chr3_-_34069637 0.41 ENSDART00000151588
immunoglobulin heavy variable 9-1
chr24_+_38522254 0.41 ENSDART00000156189
si:ch1073-66l23.1
chr6_-_24143923 0.41 ENSDART00000157948
si:ch73-389b16.1
chr7_+_15736230 0.40 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr1_+_59073436 0.40 ENSDART00000161642
si:zfos-2330d3.3
chr13_-_33134611 0.40 ENSDART00000026280
pleckstrin 2
chr8_+_6576940 0.40 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr4_-_13518381 0.39 ENSDART00000067153
interferon, gamma 1-1
chr5_-_29531948 0.39 ENSDART00000098360
arrestin domain containing 1a
chr7_+_33172066 0.39 ENSDART00000174013
si:ch211-194p6.12
chr11_+_13629528 0.39 ENSDART00000186509
si:ch211-1a19.3
chr24_+_30215475 0.38 ENSDART00000164717
si:ch73-358j7.2
chr3_-_48259289 0.38 ENSDART00000160717
zinc finger protein 750
chr21_+_11778823 0.38 ENSDART00000031786
glutaredoxin (thioltransferase)
chr17_+_21452258 0.38 ENSDART00000157098
phospholipase A2, group IVF, tandem duplicate 1
chr7_-_8417315 0.37 ENSDART00000173046
jacalin 1
chr11_+_13630107 0.37 ENSDART00000172220
si:ch211-1a19.3
chr3_-_34100700 0.37 ENSDART00000151628
immunoglobulin heavy variable 6-1
chr19_-_7420867 0.37 ENSDART00000081741
RAB25, member RAS oncogene family a
chr14_-_1538600 0.37 ENSDART00000180925

chr20_-_26532167 0.37 ENSDART00000061914
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr16_-_51288178 0.36 ENSDART00000079864
zgc:173729
chr8_+_44358443 0.36 ENSDART00000189130
ENSDART00000189212

chr13_+_18533005 0.36 ENSDART00000136024
finTRIM family, member 14-like
chr14_-_34605607 0.36 ENSDART00000191608
actin filament associated protein 1-like 1a
chr1_+_57787642 0.36 ENSDART00000127091
si:dkey-1c7.2
chr2_-_41861040 0.35 ENSDART00000045763
kelch-like ECH-associated protein 1a
chr2_+_31671545 0.35 ENSDART00000145446
atypical chemokine receptor 4a
chr4_+_77933084 0.35 ENSDART00000148728
protein kinase C and casein kinase substrate in neurons 2
chr25_-_22191733 0.35 ENSDART00000067478
plakophilin 3a
chr22_-_17489040 0.35 ENSDART00000141286
si:ch211-197g15.6
chr10_+_28428222 0.34 ENSDART00000135003
si:ch211-222e20.4
chr4_+_16715267 0.34 ENSDART00000143849
plakophilin 2
chr13_-_51846224 0.34 ENSDART00000184663

chr22_+_19218733 0.33 ENSDART00000183212
ENSDART00000133595
si:dkey-21e2.7
chr20_-_26531850 0.33 ENSDART00000183317
ENSDART00000131994
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr8_+_28695914 0.33 ENSDART00000033386
osteoclast stimulatory transmembrane protein
chr1_-_52498146 0.33 ENSDART00000122217
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr22_-_10110959 0.33 ENSDART00000031005
ENSDART00000147580
glutaminase 2b (liver, mitochondrial)
chr3_+_32118670 0.33 ENSDART00000055287
ENSDART00000111688
zgc:109934
chr23_+_19213472 0.33 ENSDART00000185985
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b
chr16_-_21785261 0.32 ENSDART00000078858
si:ch73-86n18.1
chr2_-_3437862 0.32 ENSDART00000053012
cytochrome P450, family 8, subfamily B, polypeptide 1
chr11_-_24681292 0.32 ENSDART00000089601
olfactomedin-like 3b
chr6_-_442163 0.32 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
GRB2-related adaptor protein 2b
chr15_+_1137337 0.31 ENSDART00000191508
purinergic receptor P2Y13
chr21_-_21020708 0.30 ENSDART00000064032
eukaryotic translation initiation factor 4E binding protein 1
chr4_+_77948970 0.30 ENSDART00000149636
protein kinase C and casein kinase substrate in neurons 2
chr15_-_4568154 0.30 ENSDART00000155254
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr3_+_1179601 0.30 ENSDART00000173378
TRIO and F-actin binding protein b
chr25_+_23336310 0.30 ENSDART00000156457
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 2
chr22_-_26595027 0.29 ENSDART00000184162

chr22_+_19247255 0.29 ENSDART00000144053
si:dkey-21e2.10
chr19_+_15440841 0.29 ENSDART00000182329
lin-28 homolog A (C. elegans)
chr25_+_13205878 0.29 ENSDART00000162319
ENSDART00000162283
si:ch211-147m6.2
chr22_+_16497670 0.29 ENSDART00000014330
immediate early response 5
chr19_+_2670130 0.29 ENSDART00000152152
si:ch73-24k9.2
chr9_+_11293830 0.29 ENSDART00000144440
wingless-type MMTV integration site family, member 6b
chr19_+_348729 0.28 ENSDART00000114284
MCL1, BCL2 family apoptosis regulator a
chr23_+_16807785 0.28 ENSDART00000146992
zgc:114081
chr4_-_77216726 0.28 ENSDART00000099943
proteasome subunit beta 10
chr24_+_264839 0.27 ENSDART00000066872
chemokine (C-C motif) receptor 12b, tandem duplicate 2
chr1_-_52497834 0.27 ENSDART00000136469
ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr20_+_7084154 0.27 ENSDART00000136448
finTRIM family, member 85
chr7_-_8490886 0.27 ENSDART00000159012
jacalin 6
chr22_-_5006801 0.27 ENSDART00000106166
retinal homeobox gene 1
chr22_+_19266995 0.27 ENSDART00000133995
ENSDART00000144963
si:dkey-21e2.12
chr22_+_8979955 0.27 ENSDART00000144005
si:ch211-213a13.1
chr12_-_22355430 0.27 ENSDART00000153296
ENSDART00000056919
ENSDART00000159036
N-ethylmaleimide-sensitive factor b
chr23_-_30045661 0.27 ENSDART00000122239
ENSDART00000103480
coiled-coil domain containing 187
chr5_-_1047504 0.27 ENSDART00000159346
methyl-CpG binding domain protein 2
chr7_-_8438657 0.26 ENSDART00000173054
si:dkeyp-32g11.8
chr24_-_23998897 0.26 ENSDART00000130053
zmp:0000000991
chr2_-_985417 0.26 ENSDART00000140540
si:ch211-241e1.3
chr2_-_49997055 0.26 ENSDART00000140294
si:ch211-106n13.3
chr7_+_14005111 0.26 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr8_+_8671229 0.26 ENSDART00000131963
ubiquitin specific peptidase 11
chr8_-_18010735 0.26 ENSDART00000125014
acyl-CoA thioesterase 11b
chr7_+_17443567 0.26 ENSDART00000060383
novel immune-type receptor 2b
chr18_+_30421528 0.26 ENSDART00000140908
Gse1 coiled-coil protein
chr25_-_29072162 0.26 ENSDART00000169269
AT rich interactive domain 3B (BRIGHT-like)
chr24_+_260902 0.26 ENSDART00000151992
chemokine (C-C motif) receptor 12b, tandem duplicate 1
chr6_+_56147812 0.25 ENSDART00000150219
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr6_+_612594 0.25 ENSDART00000150903
kynureninase
chr4_-_53047883 0.25 ENSDART00000157496
si:dkey-201g16.5
chr14_-_34605804 0.25 ENSDART00000144547
actin filament associated protein 1-like 1a
chr4_-_76488581 0.25 ENSDART00000174291
finTRIM family, member 51
chr11_-_27821 0.25 ENSDART00000158769
ENSDART00000172970
ENSDART00000173118
ENSDART00000168674
ENSDART00000163545
ENSDART00000173411
ENSDART00000172132
sp1 transcription factor
chr2_+_17524278 0.25 ENSDART00000165633
Pim proto-oncogene, serine/threonine kinase, related 196
chr3_+_16976095 0.25 ENSDART00000112450
caveolae associated protein 1a
chr6_+_39108858 0.25 ENSDART00000154232
ENSDART00000192092
protease, serine, 60.3
chr11_-_23501467 0.25 ENSDART00000169066
pleckstrin homology domain containing, family A member 6
chr1_-_40914752 0.24 ENSDART00000113087
H6 family homeobox 1
chr9_-_9992697 0.24 ENSDART00000123415
UDP glucuronosyltransferase 1 family a, b
chr14_+_21699414 0.24 ENSDART00000169942
syntaxin 3A
chr7_-_8504355 0.24 ENSDART00000173067
hypothetical protein LOC564660
chr23_+_1730663 0.24 ENSDART00000149545
transglutaminase 1, K polypeptide
chr23_+_25856541 0.24 ENSDART00000145426
ENSDART00000028236
hepatocyte nuclear factor 4, alpha
chr3_-_8765165 0.24 ENSDART00000191131

chr2_+_30379650 0.24 ENSDART00000129542
cysteine-rich secretory protein LCCL domain containing 1b
chr19_+_37118547 0.24 ENSDART00000103163
connexin 30.9
chr3_-_32859335 0.24 ENSDART00000158916
si:dkey-16l2.20
chr23_+_5524247 0.24 ENSDART00000189679
ENSDART00000083622
TEA domain family member 3 a
chr14_+_29941445 0.23 ENSDART00000181761
family with sequence similarity 149 member A
chr4_-_11132617 0.23 ENSDART00000150250
si:dkey-21h14.9
chr4_-_41582875 0.23 ENSDART00000182308
ENSDART00000172173
ENSDART00000163135
si:dkeyp-44d3.5
chr3_-_584950 0.23 ENSDART00000164752
diverse immunoglobulin domain-containing protein 1.1
chr3_-_34082283 0.23 ENSDART00000151264
immunoglobulin heavy variable 4-3
chr8_-_20291922 0.23 ENSDART00000148304
myosin IF
chr11_+_37638873 0.23 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
SH2 domain containing 5
chr3_+_29476085 0.23 ENSDART00000184495
ENSDART00000181058
family with sequence similarity 83, member Fa
chr1_+_55452892 0.22 ENSDART00000122508

chr25_+_3549401 0.22 ENSDART00000166312
coiled-coil domain containing 77
chr21_+_45316330 0.22 ENSDART00000056474
ENSDART00000149314
ENSDART00000149272
ENSDART00000149156
ENSDART00000099497
transcription factor 7
chr9_+_20483846 0.22 ENSDART00000192067
ENSDART00000145111
poly (ADP-ribose) polymerase family, member 4
chr3_-_43954343 0.22 ENSDART00000157580
ubiquitin family domain containing 1
chr24_-_38121920 0.22 ENSDART00000137056
si:ch211-234p6.9
chr2_+_29995590 0.22 ENSDART00000151906
RNA binding motif protein 33b
chr23_-_4933508 0.22 ENSDART00000137578
ENSDART00000141196
nerve growth factor a (beta polypeptide)
chr1_+_41588170 0.22 ENSDART00000139175
si:dkey-56e3.2
chr4_+_54618332 0.22 ENSDART00000171824
si:ch211-227e10.2
chr20_-_25626198 0.21 ENSDART00000126716
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr17_-_28707898 0.21 ENSDART00000135752
ENSDART00000061853
adaptor-related protein complex 4, sigma 1 subunit
chr8_-_38105053 0.21 ENSDART00000131546
adhesion G protein-coupled receptor A2
chr9_-_21838045 0.21 ENSDART00000147471
aconitate decarboxylase 1
chr11_+_43401592 0.21 ENSDART00000112468
vasoactive intestinal peptide b
chr16_+_41517188 0.21 ENSDART00000049976
si:dkey-11p23.7
chr10_+_4987766 0.21 ENSDART00000121959
si:ch73-234b20.5
chr6_+_29791164 0.21 ENSDART00000017424
prothymosin, alpha a
chr4_+_25181572 0.21 ENSDART00000078529
ENSDART00000136643
Kin17 DNA and RNA binding protein
chr17_-_26868169 0.21 ENSDART00000157204
si:dkey-221l4.10
chr25_+_36292465 0.21 ENSDART00000152649
brambleberry
chr17_-_15600455 0.20 ENSDART00000110272
ENSDART00000156911
si:ch211-266g18.9
chr5_+_15819651 0.20 ENSDART00000081230
ENSDART00000186969
ENSDART00000134206
heat shock protein b8
chr18_+_40993196 0.20 ENSDART00000115111
si:dkey-283j8.1
chr22_-_22337382 0.20 ENSDART00000144684
si:ch211-129c21.1
chr22_+_9862466 0.20 ENSDART00000146864
si:dkey-253d23.3
chr11_+_10975012 0.20 ENSDART00000192872
integrin, beta 6
chr5_+_1933131 0.20 ENSDART00000061693
si:ch73-55i23.1
chr25_+_29474583 0.20 ENSDART00000191189
interleukin 17 receptor E-like
chr23_-_1017605 0.20 ENSDART00000138290
cadherin 26, tandem duplicate 1
chr2_+_38731696 0.20 ENSDART00000181733

chr2_+_13710439 0.19 ENSDART00000155712
EBNA1 binding protein 2
chr14_+_33882973 0.19 ENSDART00000019396
chloride intracellular channel 2
chr24_-_6078222 0.19 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr3_-_34816893 0.19 ENSDART00000084448
ENSDART00000154696
proteasome 26S subunit, non-ATPase 11a
chr25_+_8955530 0.19 ENSDART00000156444
si:ch211-256a21.4
chr16_-_28878080 0.19 ENSDART00000149501
si:dkey-239n17.4
chr11_+_24251141 0.19 ENSDART00000182684
purine nucleoside phosphorylase 4a
chr11_-_12198765 0.19 ENSDART00000104203
ENSDART00000128364
ENSDART00000166887
ENSDART00000041533
kertain 95
chr23_-_33738945 0.19 ENSDART00000136386
si:ch211-210c8.7
chr14_-_33613794 0.19 ENSDART00000010022
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr23_-_1017428 0.18 ENSDART00000110588
ENSDART00000183158
cadherin 26, tandem duplicate 1
chr19_-_27550768 0.18 ENSDART00000142313
si:dkeyp-46h3.8
chr19_-_20403318 0.18 ENSDART00000136826
deleted in azoospermia-like
chr4_-_19742300 0.18 ENSDART00000066964
ENSDART00000100952
hepatocyte growth factor a
chr7_-_5125799 0.17 ENSDART00000173390
leukotriene B4 receptor 2a
chr10_+_9092815 0.17 ENSDART00000064966
sorting nexin 18b
chr7_-_25697285 0.17 ENSDART00000082620
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr7_-_8602864 0.17 ENSDART00000173291
jacalin 2
chr3_-_21094437 0.17 ENSDART00000153739
ENSDART00000109790
nemo-like kinase, type 1
chr3_-_38918697 0.17 ENSDART00000145630
si:dkey-106c17.2
chr5_-_9760173 0.17 ENSDART00000172523
discoidin domain receptor family, member 2, like

Network of associatons between targets according to the STRING database.

First level regulatory network of fosb+fosl2+si:ch211-153j24.3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.2 1.0 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 0.5 GO:0010525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.4 GO:0002676 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 1.0 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.3 GO:0043388 cytidine to uridine editing(GO:0016554) positive regulation of DNA binding(GO:0043388)
0.1 0.5 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0045723 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.3 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.2 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.1 0.3 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.7 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.7 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.2 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 0.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.3 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.2 GO:0043084 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.6 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.7 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.5 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778) monocyte activation(GO:0042117)
0.0 0.3 GO:2001270 regulation of execution phase of apoptosis(GO:1900117) negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.0 0.2 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.2 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0070254 mucus secretion(GO:0070254)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.2 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.0 0.3 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.1 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.0 0.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.4 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.5 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 1.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.8 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0098773 trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.0 0.1 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.1 GO:0030325 adrenal gland development(GO:0030325)
0.0 1.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0000811 GINS complex(GO:0000811)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.7 GO:0030057 desmosome(GO:0030057)
0.1 0.2 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.4 GO:0016234 inclusion body(GO:0016234)
0.0 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.1 0.4 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.7 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.5 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.6 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 0.4 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.2 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.3 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease