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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxg1a+foxg1c+foxg1d

Z-value: 0.81

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Transcription factors associated with foxg1a+foxg1c+foxg1d

Gene Symbol Gene ID Gene Info
foxg1c
ENSDARG00000068380 forkhead box G1c
foxg1d
ENSDARG00000070053 forkhead box G1d
foxg1a
ENSDARG00000070769 forkhead box G1a
foxg1c
ENSDARG00000114414 forkhead box G1c

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxg1adr11_v1_chr17_-_29119362_291193620.913.1e-02Click!
foxg1ddr11_v1_chr13_+_255067_255067-0.632.5e-01Click!
foxg1cdr11_v1_chr18_-_40901707_40901707-0.415.0e-01Click!

Activity profile of foxg1a+foxg1c+foxg1d motif

Sorted Z-values of foxg1a+foxg1c+foxg1d motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_18104235 1.12 ENSDART00000145342
cbln1
cerebellin 1 precursor
chr18_-_38087875 1.03 ENSDART00000111301
luzp2
leucine zipper protein 2
chr3_-_15264698 0.93 ENSDART00000111948
ENSDART00000142594
sez6l2
seizure related 6 homolog (mouse)-like 2
chr11_+_13058613 0.91 ENSDART00000161532
zfyve9b
zinc finger, FYVE domain containing 9b
chr14_-_2361692 0.88 ENSDART00000167696
PCDHGC3 (1 of many)
si:ch73-233f7.4
chr18_-_38088099 0.87 ENSDART00000146120
luzp2
leucine zipper protein 2
chr24_+_11106402 0.78 ENSDART00000146697
prlh2
prolactin releasing hormone 2
chr15_-_19250543 0.76 ENSDART00000092705
ENSDART00000138895
igsf9ba
immunoglobulin superfamily, member 9Ba
chr17_-_15657029 0.66 ENSDART00000153925
fut9a
fucosyltransferase 9a
chr22_-_38543630 0.57 ENSDART00000172029
si:ch211-126j24.1
si:ch211-126j24.1
chr6_+_36942966 0.56 ENSDART00000028895
negr1
neuronal growth regulator 1
chr21_+_43669943 0.54 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr25_-_35664817 0.52 ENSDART00000148718
lrrk2
leucine-rich repeat kinase 2
chr24_+_29382109 0.50 ENSDART00000184620
ENSDART00000188414
ENSDART00000186132
ENSDART00000191489
ntng1a
netrin g1a
chr11_-_42554290 0.49 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr3_+_23248542 0.48 ENSDART00000185765
ENSDART00000192332
ppp1r9ba
protein phosphatase 1, regulatory subunit 9Ba
chr16_-_18702249 0.48 ENSDART00000191595
fhod3b
formin homology 2 domain containing 3b
chr3_+_23248704 0.47 ENSDART00000156032
ppp1r9ba
protein phosphatase 1, regulatory subunit 9Ba
chr4_+_3287819 0.46 ENSDART00000168633
CABZ01085700.1

chr4_+_14343706 0.43 ENSDART00000142845
prl2
prolactin 2
chr24_+_29381946 0.42 ENSDART00000189551
ntng1a
netrin g1a
chr23_+_5977965 0.41 ENSDART00000115403
ENSDART00000183147
NAV1 (1 of many)
neuron navigator 1
chr25_-_26673570 0.40 ENSDART00000154917
ciartb
circadian associated repressor of transcription b
chr4_-_8902406 0.40 ENSDART00000192962
mpped1
metallophosphoesterase domain containing 1
chr12_+_39685485 0.39 ENSDART00000163403
LO017650.1

chr5_-_21044693 0.39 ENSDART00000140298
si:dkey-13n15.2
si:dkey-13n15.2
chr20_+_38032143 0.38 ENSDART00000032161
galnt14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_-_20952187 0.37 ENSDART00000074327
igfbp2a
insulin-like growth factor binding protein 2a
chr24_+_19591893 0.35 ENSDART00000152026
slco5a1a
solute carrier organic anion transporter family member 5A1a
chr9_+_38163876 0.34 ENSDART00000137955
clasp1a
cytoplasmic linker associated protein 1a
chr12_-_17897134 0.33 ENSDART00000066407
nptx2b
neuronal pentraxin IIb
chr4_+_3980247 0.32 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr19_-_30904590 0.31 ENSDART00000137633
si:ch211-194e15.5
si:ch211-194e15.5
chr3_+_41726360 0.31 ENSDART00000154401
chst12a
carbohydrate (chondroitin 4) sulfotransferase 12a
chr14_-_30452218 0.26 ENSDART00000011480
zdhhc2
zinc finger, DHHC-type containing 2
chr17_-_31719071 0.25 ENSDART00000136199
dtd2
D-tyrosyl-tRNA deacylase 2
chr17_-_4252221 0.25 ENSDART00000152020
gdf3
growth differentiation factor 3
chr18_+_16246806 0.25 ENSDART00000142584
alx1
ALX homeobox 1
chr2_-_7246848 0.25 ENSDART00000146434
zgc:153115
zgc:153115
chr7_-_8881514 0.24 ENSDART00000081620
vax2
ventral anterior homeobox 2
chr5_+_22791686 0.22 ENSDART00000014806
npas2
neuronal PAS domain protein 2
chr4_+_1283068 0.22 ENSDART00000167233
chrm2a
cholinergic receptor, muscarinic 2a
chr15_-_30815826 0.22 ENSDART00000156160
ENSDART00000145918
msi2b
musashi RNA-binding protein 2b
chr1_-_50710468 0.21 ENSDART00000080389
fam13a
family with sequence similarity 13, member A
chr2_-_7246338 0.21 ENSDART00000186735
zgc:153115
zgc:153115
chr19_-_19025998 0.19 ENSDART00000186156
ENSDART00000163359
ENSDART00000167951
dync1li1
dynein, cytoplasmic 1, light intermediate chain 1
chr18_-_44935174 0.18 ENSDART00000081025
pex16
peroxisomal biogenesis factor 16
chr7_+_47243564 0.17 ENSDART00000098942
ENSDART00000162237
znf507
zinc finger protein 507
chr16_-_13613475 0.16 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr15_-_16155729 0.14 ENSDART00000192212
si:ch211-259g3.4
si:ch211-259g3.4
chr19_-_82504 0.13 ENSDART00000027864
ENSDART00000160560
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr20_+_34320635 0.12 ENSDART00000153207
ivns1abpa
influenza virus NS1A binding protein a
chr14_+_2095394 0.11 ENSDART00000186847
CT573264.2

chr7_+_9189547 0.09 ENSDART00000169783
pcsk6
proprotein convertase subtilisin/kexin type 6
chr9_+_2002701 0.09 ENSDART00000082329
evx2
even-skipped homeobox 2
chr18_-_34170918 0.07 ENSDART00000015079
slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr23_-_15090782 0.06 ENSDART00000133624
si:ch211-218g4.2
si:ch211-218g4.2
chr3_+_28860283 0.05 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr5_-_38122126 0.04 ENSDART00000141791
ENSDART00000170528
si:ch211-284e13.6
si:ch211-284e13.6
chr18_+_20482369 0.04 ENSDART00000100668
kbtbd4
kelch repeat and BTB (POZ) domain containing 4
chr18_-_34171280 0.02 ENSDART00000122321
slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr3_+_35406998 0.02 ENSDART00000102994
rbbp6
retinoblastoma binding protein 6
chr1_-_46875493 0.01 ENSDART00000115081
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr20_-_14665002 0.00 ENSDART00000152816
scrn2
secernin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of foxg1a+foxg1c+foxg1d

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.2 GO:0003161 cardiac conduction system development(GO:0003161) negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.3 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.7 GO:0036065 fucosylation(GO:0036065)
0.0 0.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.4 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.9 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.3 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.9 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA