Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation
Downloads

Results for foxo3a

Z-value: 0.57

Motif logo

Transcription factors associated with foxo3a

Gene Symbol Gene ID Gene Info
ENSDARG00000023058 forkhead box O3A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxo3adr11_v1_chr17_+_6793001_67930010.385.3e-01Click!

Activity profile of foxo3a motif

Sorted Z-values of foxo3a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_36378494 0.62 ENSDART00000058503
glycoprotein M6Aa
chr19_+_2275019 0.50 ENSDART00000136138
integrin, beta 8
chr12_-_13886952 0.39 ENSDART00000110503
ADAM metallopeptidase domain 11
chr15_+_8043751 0.39 ENSDART00000193701
cell adhesion molecule 2b
chr5_+_36611128 0.38 ENSDART00000097684
neuro-oncological ventral antigen 1
chr11_-_44409856 0.33 ENSDART00000162886
interleukin 1 receptor accessory protein-like 1b
chr19_-_28367413 0.32 ENSDART00000079092
si:dkey-261i16.5
chr3_-_28258462 0.32 ENSDART00000191573
RNA binding fox-1 homolog 1
chr13_+_1100197 0.32 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr8_-_25011157 0.32 ENSDART00000078795
adenosylhomocysteinase-like 1
chr15_+_16897554 0.31 ENSDART00000154679
yippee-like 2b
chr6_+_48618512 0.31 ENSDART00000111190
si:dkey-238f9.1
chr3_+_54168007 0.30 ENSDART00000109894
olfactomedin 2a
chr20_+_30445971 0.30 ENSDART00000153150
myelin transcription factor 1-like, a
chr16_-_22251414 0.30 ENSDART00000158500
ENSDART00000179998
ATPase phospholipid transporting 8B2
chr3_-_51912019 0.30 ENSDART00000149914
apoptosis-associated tyrosine kinase a
chr4_-_4256300 0.30 ENSDART00000103319
ENSDART00000150279
CD9 molecule b
chr19_+_10396042 0.29 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr13_+_24834199 0.29 ENSDART00000101274
zgc:153981
chr1_-_8917902 0.29 ENSDART00000137900
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr1_-_9277986 0.28 ENSDART00000146065
ENSDART00000114876
ENSDART00000132812
ubinuclein 1
chr18_+_1703984 0.28 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr11_+_18873619 0.27 ENSDART00000176141
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr6_-_52156427 0.27 ENSDART00000082821
regulating synaptic membrane exocytosis 4
chr25_-_11088839 0.26 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr20_-_39273987 0.25 ENSDART00000127173
clusterin
chr5_-_28679135 0.24 ENSDART00000193585
tenascin C
chr14_-_34044369 0.24 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr8_+_10823069 0.23 ENSDART00000081341
mitogen-activated protein kinase 13
chr15_+_23657051 0.23 ENSDART00000078336
kinesin light chain 3
chr18_-_26675699 0.23 ENSDART00000113280
si:ch211-69m14.1
chr21_+_32338897 0.22 ENSDART00000110137
si:ch211-247j9.1
chr22_-_7129631 0.21 ENSDART00000171359
acid-sensing (proton-gated) ion channel 1b
chr6_-_12172424 0.20 ENSDART00000109344
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr18_+_15271993 0.20 ENSDART00000099777
si:dkey-103i16.6
chr9_+_17971935 0.19 ENSDART00000149736
A kinase (PRKA) anchor protein 11
chr7_+_47287307 0.19 ENSDART00000114669
dpy-19 like C-mannosyltransferase 3
chr12_+_12112384 0.19 ENSDART00000152431
glutamate receptor, ionotropic, delta 1b
chr8_+_26432677 0.19 ENSDART00000078369
ENSDART00000131925
zgc:136971
chr6_-_12270226 0.18 ENSDART00000180473
plakophilin 4
chr15_-_31498123 0.18 ENSDART00000153665
si:dkey-1m11.6
chr4_-_14926637 0.17 ENSDART00000110199
PR domain containing 4
chr8_+_40081403 0.17 ENSDART00000138036
leucine rich repeat containing 75Ba
chr13_+_28854438 0.17 ENSDART00000193407
ENSDART00000189554

chr14_-_25599002 0.16 ENSDART00000040955
solute carrier family 25, member 48
chr23_-_12158685 0.16 ENSDART00000135035
family with sequence similarity 217, member B
chr1_-_6494384 0.16 ENSDART00000109356
Kruppel-like factor 7a
chr4_+_5741733 0.16 ENSDART00000110243
POU class 3 homeobox 2a
chr9_+_29603649 0.16 ENSDART00000140477
mcf.2 cell line derived transforming sequence-like b
chr7_+_38278860 0.15 ENSDART00000016265
low density lipoprotein receptor-related protein 3
chr9_-_3400727 0.15 ENSDART00000183979
ENSDART00000111386
distal-less homeobox 2a
chr6_-_18698456 0.15 ENSDART00000166587
rhomboid, veinlet-like 3 (Drosophila)
chr3_+_19207176 0.15 ENSDART00000087803
relaxin 3a
chr10_-_20669635 0.15 ENSDART00000131361
Kv channel interacting protein 3b, calsenilin
chr1_+_16127825 0.14 ENSDART00000122503
tumor suppressor candidate 3
chr20_-_39273505 0.14 ENSDART00000153114
clusterin
chr11_+_6819050 0.14 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr22_+_30335936 0.14 ENSDART00000059923
max interactor 1, dimerization protein
chr15_-_25527580 0.13 ENSDART00000167005
ENSDART00000157498
hypoxia-inducible factor 1, alpha subunit, like
chr5_-_38384289 0.13 ENSDART00000135260
misshapen-like kinase 1
chr6_+_9398074 0.13 ENSDART00000151772
kalirin RhoGEF kinase b
chr24_+_17007407 0.13 ENSDART00000110652
zinc finger protein, X-linked
chr1_+_45839927 0.13 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
mitogen-activated protein kinase kinase 7
chr21_-_42202792 0.12 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr2_+_9061885 0.12 ENSDART00000028906
phosphatidylinositol glycan anchor biosynthesis, class K
chr20_+_40457599 0.12 ENSDART00000017553
serine incorporator 1
chr21_+_32339158 0.12 ENSDART00000161723
si:ch211-247j9.1
chr24_-_6678640 0.12 ENSDART00000042478
enkurin, TRPC channel interacting protein
chr1_+_45969240 0.11 ENSDART00000042086
Rho guanine nucleotide exchange factor (GEF) 7b
chr21_-_32301109 0.11 ENSDART00000139890
CDC-like kinase 4b
chr12_-_22509069 0.10 ENSDART00000179755
ENSDART00000109707
neuralized E3 ubiquitin protein ligase 4
chr14_-_48939560 0.10 ENSDART00000021736
short coiled-coil protein b
chr13_+_12761707 0.10 ENSDART00000015127
zgc:100846
chr14_-_30960470 0.10 ENSDART00000129989
si:ch211-191o15.6
chr25_+_13662606 0.09 ENSDART00000008989
coiled-coil domain containing 113
chr25_+_3035384 0.09 ENSDART00000184219
ENSDART00000149360
mannose phosphate isomerase
chr9_-_10532591 0.09 ENSDART00000175269
thrombospondin, type I, domain containing 7Ba
chr9_-_16876474 0.09 ENSDART00000185450
F-box and leucine-rich repeat protein 3a
chr23_-_33680265 0.09 ENSDART00000138416
transcription factor CP2
chr8_+_7778770 0.09 ENSDART00000171325
transcription factor binding to IGHM enhancer 3a
chr16_+_25011994 0.08 ENSDART00000157312
zinc finger protein 1035
chr16_-_32671782 0.08 ENSDART00000123980
PNN-interacting serine/arginine-rich protein
chr1_-_28749604 0.08 ENSDART00000148522
zgc:172295
chr3_-_7656059 0.08 ENSDART00000170917
JunB proto-oncogene, AP-1 transcription factor subunit b
chr3_+_24458899 0.08 ENSDART00000156655
chromobox homolog 6b
chr2_+_44615153 0.08 ENSDART00000156523
YEATS domain containing 2
chr10_+_2529037 0.07 ENSDART00000123467
zmp:0000001301
chr16_-_36748374 0.07 ENSDART00000133310
phosphoinositide-3-kinase, regulatory subunit 4
chr20_+_19562383 0.07 ENSDART00000103798
NME/NM23 nucleoside diphosphate kinase 6
chr9_-_16877456 0.07 ENSDART00000161105
ENSDART00000160869
F-box and leucine-rich repeat protein 3a
chr1_+_8984068 0.07 ENSDART00000122568
toll-like receptor 2
chr2_-_25553607 0.07 ENSDART00000150075
ENSDART00000078695
growth hormone secretagogue receptor a
chr3_+_53116172 0.07 ENSDART00000115117
bromodomain containing 4
chr11_-_18323059 0.07 ENSDART00000182590
Scm like with four mbt domains 1
chr4_-_6809323 0.06 ENSDART00000099467
interferon-related developmental regulator 1
chr10_-_8197049 0.06 ENSDART00000129467
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr5_+_53009083 0.06 ENSDART00000157836
histidine triad nucleotide binding protein 2
chr7_+_24023653 0.06 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr24_-_18659147 0.05 ENSDART00000166039
zgc:66014
chr16_-_12496632 0.05 ENSDART00000019941
solute carrier family 2 (facilitated glucose transporter), member 3b
chr1_+_41886830 0.05 ENSDART00000185887
ENSDART00000084735
si:dkey-37g12.1
chr10_+_42589707 0.05 ENSDART00000075269
fibroblast growth factor receptor 1b
chr23_+_22785375 0.04 ENSDART00000142085
arginine-glutamic acid dipeptide (RE) repeats a
chr12_+_27213733 0.04 ENSDART00000133048
neighbor of brca1 gene 1a
chr21_-_11820379 0.04 ENSDART00000126640
si:dkey-6b12.5
chr16_-_32671998 0.04 ENSDART00000161395
PNN-interacting serine/arginine-rich protein
chr6_-_40922971 0.04 ENSDART00000155363
SFI1 centrin binding protein
chr16_-_49646625 0.04 ENSDART00000101629
EF-hand domain family, member B
chr3_-_26191960 0.04 ENSDART00000113843
yippee-like 3
chr3_+_55031685 0.04 ENSDART00000132587
N-methylpurine DNA glycosylase
chr6_-_54111928 0.03 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr4_-_14926106 0.03 ENSDART00000147629
PR domain containing 4
chr10_-_15879569 0.03 ENSDART00000136789
tight junction protein 2a (zona occludens 2)
chr11_+_2710530 0.03 ENSDART00000132768
ENSDART00000030921
ENSDART00000040147
mitogen-activated protein kinase 14b
chr17_+_44756247 0.03 ENSDART00000153773
CLOCK-interacting pacemaker a
chr3_+_27786601 0.03 ENSDART00000086994
N-acetyltransferase 15 (GCN5-related, putative)
chr23_-_24226533 0.03 ENSDART00000109134
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr5_-_18046053 0.03 ENSDART00000144898
ring finger protein 215
chr18_-_40913294 0.03 ENSDART00000059196
ENSDART00000098878
polymerase (RNA) II (DNA directed) polypeptide I
chr16_+_49647402 0.03 ENSDART00000015694
ENSDART00000132547
RAB5A, member RAS oncogene family, b
chr2_+_23790748 0.02 ENSDART00000041877
cysteine-serine-rich nuclear protein 1a
chr8_+_53204027 0.02 ENSDART00000135353
cilia and flagella associated protein 74
chr9_+_13229585 0.02 ENSDART00000154879
ENSDART00000141705
calcium responsive transcription factor
chr3_-_45308394 0.02 ENSDART00000155324
3-phosphoinositide dependent protein kinase 1a
chr9_+_13230214 0.02 ENSDART00000017932
ENSDART00000179850
calcium responsive transcription factor
chr13_+_45980163 0.02 ENSDART00000074547
ENSDART00000005195
BSD domain containing 1
chr15_+_20543770 0.02 ENSDART00000092357
small G protein signaling modulator 2
chr14_-_33177935 0.02 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr18_-_12052132 0.02 ENSDART00000074361
zgc:110789
chr13_+_29926094 0.02 ENSDART00000057528
CUE domain containing 2
chr19_-_10324182 0.02 ENSDART00000151352
ENSDART00000151162
ENSDART00000023571
U2 small nuclear RNA auxiliary factor 2b
chr2_-_47957673 0.02 ENSDART00000056305
frizzled class receptor 8b
chr17_-_50220228 0.02 ENSDART00000058707
Jun dimerization protein 2a
chr5_+_24063046 0.01 ENSDART00000051548
ENSDART00000133355
ENSDART00000142268
G protein pathway suppressor 2
chr25_+_17920361 0.01 ENSDART00000185644
BLOC-1 related complex subunit 5
chr3_-_20063671 0.01 ENSDART00000056614
ENSDART00000126915
upstream binding transcription factor, RNA polymerase I
chr13_+_5978809 0.01 ENSDART00000102563
ENSDART00000121598
PHD finger protein 10
chr19_+_1878500 0.01 ENSDART00000113392
gamma-glutamylcyclotransferase a
chr25_-_18249751 0.01 ENSDART00000153950
si:dkey-106n21.1
chr15_+_23784842 0.01 ENSDART00000192889
ENSDART00000138375
intraflagellar transport 20 homolog (Chlamydomonas)
chr10_+_42589391 0.01 ENSDART00000067689
ENSDART00000075259
fibroblast growth factor receptor 1b
chr5_-_69212184 0.01 ENSDART00000053963
methionine adenosyltransferase II, alpha b
chr9_+_50600355 0.01 ENSDART00000187567
fidgetin
chr9_-_13355071 0.01 ENSDART00000084055
frizzled class receptor 7a
chr16_-_44900306 0.01 ENSDART00000058380
RNA binding motif protein 42
chr15_+_19990068 0.01 ENSDART00000154033
ENSDART00000054428
zgc:112083
chr7_+_72279584 0.01 ENSDART00000172021
toll interacting protein
chr22_+_37631234 0.01 ENSDART00000007346
proteasome 26S subunit, non-ATPase 1
chr20_-_35470891 0.01 ENSDART00000152993
ENSDART00000016090
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_-_14966384 0.00 ENSDART00000105064
thioredoxin domain containing 16
chr7_+_33372680 0.00 ENSDART00000193436
ENSDART00000099988
glucuronic acid epimerase b
chr6_-_54126463 0.00 ENSDART00000161059
tumor suppressor candidate 2a
chr17_+_24718272 0.00 ENSDART00000007271
mitochondrial fission regulator 1-like
chr4_-_14207471 0.00 ENSDART00000015134
twinfilin actin-binding protein 1b
chr24_-_2312868 0.00 ENSDART00000140125
ENSDART00000138432
cullin 2
chr25_+_19149241 0.00 ENSDART00000184982
ENSDART00000067324
milk fat globule-EGF factor 8 protein b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo3a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.2 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.2 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0001964 startle response(GO:0001964)
0.0 0.5 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.0 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0036268 swimming(GO:0036268)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME KINESINS Genes involved in Kinesins