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PRJNA207719: Tissue specific transcriptome profiling

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Results for gata1a+gata2b

Z-value: 0.31

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Transcription factors associated with gata1a+gata2b

Gene Symbol Gene ID Gene Info
ENSDARG00000009094 GATA binding protein 2b
ENSDARG00000013477 GATA binding protein 1a
ENSDARG00000117116 GATA binding protein 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gata2bdr11_v1_chr6_+_40794015_407940150.108.7e-01Click!
gata1adr11_v1_chr11_-_25418856_25418856-0.009.9e-01Click!

Activity profile of gata1a+gata2b motif

Sorted Z-values of gata1a+gata2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_24287403 0.35 ENSDART00000111169
cell adhesion molecule 1a
chr22_+_15507218 0.34 ENSDART00000125450
glypican 1a
chr6_-_49159207 0.26 ENSDART00000041942
tetraspanin 2a
chr7_-_72067475 0.22 ENSDART00000017763

chr19_-_32710922 0.21 ENSDART00000004034
hippocalcin
chr4_-_1360495 0.18 ENSDART00000164623
pleiotrophin
chr22_+_635813 0.16 ENSDART00000179067

chr12_-_5505205 0.15 ENSDART00000092319
ABI family, member 3b
chr18_+_3169579 0.13 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
p21 protein (Cdc42/Rac)-activated kinase 1
chr15_-_16704417 0.10 ENSDART00000155163
calneuron 1
chr21_+_43561650 0.07 ENSDART00000085071
G protein-coupled receptor 185 a
chr19_+_12444943 0.06 ENSDART00000135706
low density lipoprotein receptor class A domain containing 4a
chr17_+_5768608 0.06 ENSDART00000157039
retinitis pigmentosa 1-like 1a
chr10_-_31175744 0.05 ENSDART00000191728
pbx/knotted 1 homeobox 2
chr10_+_42589391 0.01 ENSDART00000067689
ENSDART00000075259
fibroblast growth factor receptor 1b
chr22_+_21398508 0.01 ENSDART00000089408
ENSDART00000186091
Src homology 2 domain containing transforming protein D, b
chr16_-_35532937 0.01 ENSDART00000193209
CTP synthase 1b
chr5_+_18047111 0.00 ENSDART00000132164
histone cell cycle regulator a

Network of associatons between targets according to the STRING database.

First level regulatory network of gata1a+gata2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway