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PRJNA207719: Tissue specific transcriptome profiling

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Results for gcm2

Z-value: 1.14

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Transcription factors associated with gcm2

Gene Symbol Gene ID Gene Info
ENSDARG00000045413 glial cells missing transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gcm2dr11_v1_chr24_-_8831866_8831912-0.424.8e-01Click!

Activity profile of gcm2 motif

Sorted Z-values of gcm2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_6158933 1.51 ENSDART00000021609
glutamate decarboxylase 2
chr10_+_7182168 1.28 ENSDART00000172766
pleckstrin and Sec7 domain containing 3, like
chr16_+_45571956 1.13 ENSDART00000143867
synaptic Ras GTPase activating protein 1b
chr5_-_23317477 1.09 ENSDART00000090171
neuroligin 3b
chr10_+_7182423 1.04 ENSDART00000186788
pleckstrin and Sec7 domain containing 3, like
chr3_-_30061985 1.01 ENSDART00000189583
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr2_-_42871286 1.01 ENSDART00000087823
adenylate cyclase 8 (brain)
chr18_-_21218851 0.92 ENSDART00000060160
calbindin 2a
chr19_-_8604429 0.90 ENSDART00000151165
tripartite motif containing 46b
chr1_-_20911297 0.89 ENSDART00000078271
carboxypeptidase E
chr14_-_14746767 0.86 ENSDART00000183755
ENSDART00000190938
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
chr6_-_13308813 0.84 ENSDART00000065372
potassium inwardly-rectifying channel, subfamily J, member 3b
chr16_+_5678071 0.82 ENSDART00000011166
ENSDART00000134198
ENSDART00000131575
zgc:158689
chr3_-_6768905 0.81 ENSDART00000193638
ENSDART00000123809
ENSDART00000189440
ENSDART00000188335
microtubule associated serine/threonine kinase 1b
chr20_-_32110882 0.81 ENSDART00000030324
glutamate receptor, metabotropic 1a
chr12_+_29054907 0.80 ENSDART00000152936
gamma-aminobutyric acid (GABA) A receptor, zeta
chr12_+_29055143 0.77 ENSDART00000076322
gamma-aminobutyric acid (GABA) A receptor, zeta
chr17_+_8183393 0.75 ENSDART00000155957
tubby like protein 4b
chr13_-_44285793 0.71 ENSDART00000167383

chr3_+_46724528 0.69 ENSDART00000181358
phosphodiesterase 4A, cAMP-specific
chr5_-_34185115 0.67 ENSDART00000192771
fibrinogen C domain containing 1
chr4_+_19534833 0.67 ENSDART00000140028
leucine rich repeat containing 4.1
chr10_+_45071603 0.67 ENSDART00000186505
ENSDART00000157573
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr1_-_53756851 0.66 ENSDART00000122445
v-akt murine thymoma viral oncogene homolog 3b
chr4_-_20081621 0.60 ENSDART00000024647
DENN/MADD domain containing 6B
chr20_+_48100261 0.60 ENSDART00000158604
XK related 5a
chr16_+_25407021 0.59 ENSDART00000187489
ENSDART00000086333
jumonji, AT rich interactive domain 2a
chr14_+_7140997 0.59 ENSDART00000170994
ENSDART00000129898
cathepsin F
chr3_+_39759130 0.56 ENSDART00000185202
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr10_-_25852517 0.55 ENSDART00000191551
transient receptor potential cation channel, subfamily C, member 4a
chr5_-_21065094 0.54 ENSDART00000143785
si:dkey-13n15.2
chr6_-_46403475 0.54 ENSDART00000154148
calcium/calmodulin-dependent protein kinase Ia
chr23_+_40109353 0.52 ENSDART00000149249
growth hormone releasing hormone receptor, like
chr12_+_35011899 0.51 ENSDART00000153007
ENSDART00000153020
QKI, KH domain containing, RNA binding 2
chr21_+_25068215 0.50 ENSDART00000167523
ENSDART00000189259
DIX domain containing 1b
chr16_-_32671782 0.49 ENSDART00000123980
PNN-interacting serine/arginine-rich protein
chr21_-_1799265 0.49 ENSDART00000066623
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr18_+_43183749 0.49 ENSDART00000151166
nectin cell adhesion molecule 1b
chr17_+_23554932 0.48 ENSDART00000135814
pantothenate kinase 1a
chr14_-_27289042 0.48 ENSDART00000159727
protocadherin 11
chr17_-_35881841 0.47 ENSDART00000110040
SRY (sex determining region Y)-box 11a
chr18_-_215698 0.47 ENSDART00000147430
threonyl-tRNA synthetase-like 2
chr13_+_2448251 0.46 ENSDART00000188361
ARFGEF family member 3
chr3_-_32299892 0.46 ENSDART00000181472
si:dkey-16p21.7
chr1_+_45323400 0.45 ENSDART00000148906
ENSDART00000132366
epithelial membrane protein 1
chr6_-_55354004 0.45 ENSDART00000165911
PDX1 C-terminal inhibiting factor 1
chr20_+_17739923 0.45 ENSDART00000024627
cadherin 2, type 1, N-cadherin (neuronal)
chr8_+_23521974 0.44 ENSDART00000188130
ENSDART00000129378
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr23_+_27652906 0.43 ENSDART00000077931
wingless-type MMTV integration site family, member 1
chr10_+_4095917 0.42 ENSDART00000114533
meningioma 1a
chr4_-_760560 0.42 ENSDART00000103601
ATP/GTP binding protein-like 5
chr14_-_33177935 0.42 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr17_+_53250802 0.42 ENSDART00000143819
vasohibin 1
chr21_+_1380099 0.42 ENSDART00000184516
transcription factor 4
chr20_+_28434196 0.41 ENSDART00000034245
D4, zinc and double PHD fingers, family 3
chr6_+_42819337 0.39 ENSDART00000046498
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr23_-_36823932 0.39 ENSDART00000142305
homeodomain interacting protein kinase 1a
chr9_-_33608427 0.38 ENSDART00000100849
calcium/calmodulin-dependent serine protein kinase a
chr17_-_43665366 0.37 ENSDART00000127945
early growth response 2a
chr3_-_9722603 0.37 ENSDART00000168234
CREB binding protein b
chr22_-_20342260 0.36 ENSDART00000161610
ENSDART00000165667
transcription factor 3b
chr2_-_32505091 0.36 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr16_+_17763848 0.36 ENSDART00000149408
ENSDART00000148878
thioesterase superfamily member 4
chr5_-_25572151 0.35 ENSDART00000144995
si:dkey-229d2.4
chr21_+_349091 0.35 ENSDART00000183693
zinc finger protein 462
chr25_-_28443607 0.35 ENSDART00000157243
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr17_+_37310663 0.35 ENSDART00000157122
ELM2 and Myb/SANT-like domain containing 1b
chr10_+_37145007 0.34 ENSDART00000131777
CUE domain containing 1a
chr6_+_41096058 0.33 ENSDART00000028373
FK506 binding protein 5
chr4_+_7888047 0.33 ENSDART00000104676
calcium/calmodulin-dependent protein kinase 1Da
chr22_+_5176693 0.33 ENSDART00000160927
ceramide synthase 1
chr2_+_8717155 0.32 ENSDART00000018114
ENSDART00000137872
ENSDART00000133037
ubiquitin specific peptidase 33
chr11_-_41130239 0.32 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr14_+_44860335 0.32 ENSDART00000091620
ENSDART00000173043
ENSDART00000091625
ATPase phospholipid transporting 8A1
chr4_+_11384891 0.32 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
piccolo presynaptic cytomatrix protein a
chr20_+_54333774 0.31 ENSDART00000144633
CLOCK-interacting pacemaker b
chr14_-_2217285 0.31 ENSDART00000157949
ENSDART00000166150
ENSDART00000054891
ENSDART00000183268
protocadherin 2 alpha b2
protocadherin 2 alpha b2
chr14_-_15699528 0.31 ENSDART00000161123
neuralized E3 ubiquitin protein ligase 1B
chr14_+_2243 0.31 ENSDART00000191193
cytokine like 1
chr3_-_26171668 0.31 ENSDART00000113890
rabaptin, RAB GTPase binding effector protein 2
chr16_-_32671998 0.30 ENSDART00000161395
PNN-interacting serine/arginine-rich protein
chr21_+_21791799 0.30 ENSDART00000151759
sialidase 3 (membrane sialidase), tandem duplicate 1
chr22_+_26703026 0.29 ENSDART00000158756
CREB binding protein a
chr22_+_5176255 0.28 ENSDART00000092647
ceramide synthase 1
chr19_+_56351 0.28 ENSDART00000168334
collagen, type XIV, alpha 1b
chr13_+_31479814 0.27 ENSDART00000148112
leucine rich repeat containing 9
chr16_+_4133519 0.27 ENSDART00000174521
ENSDART00000175718
metal-regulatory transcription factor 1
chr19_-_47452874 0.27 ENSDART00000025931
transcription factor AP-2 epsilon
chr9_+_36356740 0.27 ENSDART00000139033
low density lipoprotein receptor-related protein 1Bb
chr10_-_5053589 0.27 ENSDART00000193579
transmembrane protein 150C
chr7_-_71829649 0.27 ENSDART00000160449
calcium channel, voltage-dependent, beta 2a
chr11_-_41132296 0.27 ENSDART00000162944
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr14_+_21820034 0.27 ENSDART00000122739
C-terminal binding protein 1
chr16_-_21903083 0.26 ENSDART00000165849
SET domain, bifurcated 1b
chr1_+_44941031 0.25 ENSDART00000141145
si:dkey-9i23.16
chr15_-_14469704 0.25 ENSDART00000185077
numb homolog (Drosophila)-like
chr1_+_2112726 0.24 ENSDART00000131714
ENSDART00000138396
muscleblind-like splicing regulator 2
chr23_+_5565261 0.24 ENSDART00000059307
ENSDART00000169904
sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
chr21_+_17301790 0.24 ENSDART00000145057
TSC complex subunit 1b
chr1_+_26445615 0.24 ENSDART00000180810
GTPase activating protein (SH3 domain) binding protein 2
chr14_-_1963369 0.24 ENSDART00000125521
protocadherin 2 gamma 5
chr5_+_70262153 0.23 ENSDART00000185309
zinc finger protein 618
chr7_-_4036875 0.23 ENSDART00000165021
NDRG family member 2
chr4_+_50261086 0.23 ENSDART00000140833
si:dkey-16p6.1
chr9_-_3400727 0.22 ENSDART00000183979
ENSDART00000111386
distal-less homeobox 2a
chr23_+_4646194 0.21 ENSDART00000092344

chr5_+_18925367 0.21 ENSDART00000051621
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial
chr17_+_43629008 0.20 ENSDART00000184185
ENSDART00000181681
zinc finger protein 365
chr6_+_15762647 0.20 ENSDART00000127133
ENSDART00000128939
IQ motif containing with AAA domain 1
chr17_-_35278763 0.19 ENSDART00000063437
ADAM metallopeptidase domain 17a
chr2_-_9971609 0.19 ENSDART00000137924
ENSDART00000048655
ENSDART00000131613
zgc:55943
chr21_+_27278120 0.19 ENSDART00000193882
si:dkey-175m17.7
chr12_-_7824291 0.19 ENSDART00000148673
ENSDART00000149453
ankyrin 3b
chr16_+_27564270 0.19 ENSDART00000140460
transmembrane protein 67
chr11_+_23760470 0.18 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
neurofascin homolog (chicken) a
chr20_+_43648369 0.18 ENSDART00000187930
ENSDART00000017269
poly (ADP-ribose) polymerase 1
chr8_-_28655338 0.18 ENSDART00000017440
melanocortin 3 receptor
chr10_-_302827 0.18 ENSDART00000157582
EMSY BRCA2-interacting transcriptional repressor
chr1_+_34295925 0.18 ENSDART00000075584
potassium channel tetramerisation domain containing 12.2
chr13_+_43650632 0.17 ENSDART00000141024
zinc finger, FYVE domain containing 21
chr12_-_33357655 0.17 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr19_+_7627070 0.16 ENSDART00000151078
ENSDART00000131324
pygopus homolog 2 (Drosophila)
chr20_+_26947800 0.16 ENSDART00000062066
si:dkey-177p2.6
chr8_-_1267247 0.15 ENSDART00000150064
cell division cycle 14B
chr17_+_13099476 0.15 ENSDART00000012670
pinin, desmosome associated protein
chr15_-_28618502 0.14 ENSDART00000086902
solute carrier family 6 (neurotransmitter transporter), member 4a
chr6_+_21536131 0.14 ENSDART00000113911
ENSDART00000188472
MICAL-like 1a
chr16_+_12267672 0.14 ENSDART00000060037
zgc:92606
chr1_+_26444986 0.13 ENSDART00000046376
GTPase activating protein (SH3 domain) binding protein 2
chr23_-_30960506 0.13 ENSDART00000142661
oxysterol binding protein-like 2a
chr11_-_2277081 0.13 ENSDART00000109026
zinc finger protein 740a
chr1_-_20928772 0.13 ENSDART00000078277
methylsterol monooxygenase 1
chr14_-_24101897 0.13 ENSDART00000143695
cytoplasmic polyadenylation element binding protein 4a
chr12_+_49125510 0.13 ENSDART00000185804

chr10_+_8534750 0.13 ENSDART00000183960
TBC1 domain family, member 10Ab
chr1_-_26293203 0.12 ENSDART00000180140
CXXC finger 4
chr15_-_20939579 0.12 ENSDART00000152371
ubiquitin specific peptidase 2a
chr22_+_26703518 0.11 ENSDART00000187997
ENSDART00000166775
CREB binding protein a
chr4_+_19127973 0.11 ENSDART00000136611
si:dkey-21o22.2
chr13_+_15004398 0.11 ENSDART00000057810
empty spiracles homeobox 1
chr8_+_10350122 0.11 ENSDART00000186650
ENSDART00000098009
TBC1 domain family, member 22B
chr6_+_39499623 0.10 ENSDART00000036057
si:ch211-173n18.3
chr6_+_42818963 0.10 ENSDART00000184833
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr23_-_22523303 0.10 ENSDART00000079019
splA/ryanodine receptor domain and SOCS box containing 1
chr4_-_73411863 0.10 ENSDART00000171434
zgc:162958
chr17_+_25563979 0.09 ENSDART00000045615
ENSDART00000183162
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr24_+_21346796 0.09 ENSDART00000126519
shisa family member 2b
chr4_+_50260361 0.08 ENSDART00000166894
si:dkey-16p6.1
chr1_-_57172294 0.08 ENSDART00000063774
Rac family small GTPase 1, like
chr24_-_21258945 0.07 ENSDART00000111025
BOC cell adhesion associated, oncogene regulated
chr1_-_51157660 0.07 ENSDART00000137172
jagged 1a
chr2_-_9696283 0.07 ENSDART00000165712
selenoprotein T, 1a
chr16_-_52646789 0.07 ENSDART00000035761
ubiquitin protein ligase E3 component n-recognin 5
chr8_+_50150834 0.07 ENSDART00000056074
ectonucleoside triphosphate diphosphohydrolase 4
chr19_+_4024443 0.07 ENSDART00000159215
ENSDART00000172204
MYST/Esa1-associated factor 6
chr5_-_61588998 0.06 ENSDART00000050912
peroxisomal biogenesis factor 12
chr24_+_25069609 0.06 ENSDART00000115165
APC membrane recruitment protein 2
chr17_-_35361322 0.06 ENSDART00000019617
radical S-adenosyl methionine domain containing 2
chr15_+_29123031 0.05 ENSDART00000133988
ENSDART00000060030
zgc:101731
chr25_-_21156678 0.05 ENSDART00000156257
WNK lysine deficient protein kinase 1a
chr20_-_54435287 0.05 ENSDART00000148632
YY1 transcription factor b
chr1_-_51157454 0.04 ENSDART00000047851
jagged 1a
chr1_-_13989643 0.04 ENSDART00000191046
E74-like factor 2b (ets domain transcription factor)
chr9_+_51882534 0.03 ENSDART00000165493

chr13_-_43108693 0.03 ENSDART00000164439
si:ch211-106f21.1
chr6_+_46406565 0.03 ENSDART00000168440
ENSDART00000131203
ENSDART00000138567
ENSDART00000132845
polybromo 1, like
chr25_-_21894317 0.03 ENSDART00000089642
F-box protein 31
chr21_+_20386865 0.03 ENSDART00000144366
si:dkey-30k6.5
chr3_-_45298487 0.02 ENSDART00000102245
3-phosphoinositide dependent protein kinase 1a
chr17_-_25563847 0.02 ENSDART00000040032
reticulon 4 interacting protein 1
chr6_+_23010242 0.02 ENSDART00000113116
polymerase (DNA directed), gamma 2, accessory subunit
chr21_-_43398457 0.02 ENSDART00000166530
cyclin I family, member 2
chr14_-_413273 0.02 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr19_-_81851 0.01 ENSDART00000172319
heterogeneous nuclear ribonucleoprotein R
chr7_-_7692723 0.01 ENSDART00000183352
aminoadipate aminotransferase
chr1_+_54043563 0.01 ENSDART00000149760
TRIO and F-actin binding protein a
chr21_-_3452683 0.01 ENSDART00000009740
SMAD family member 7
chr1_-_54425791 0.01 ENSDART00000039911
polycystic kidney disease 1a
chr20_+_30725778 0.01 ENSDART00000062532
NHS-like 1b
chr24_+_18299175 0.00 ENSDART00000140994
thiamin pyrophosphokinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of gcm2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.9 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.2 0.5 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 0.4 GO:0021577 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.1 0.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.1 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.4 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 1.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.3 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 2.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.6 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.5 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0051610 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.0 0.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.2 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 1.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0046048 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.0 0.6 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.3 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0002931 response to ischemia(GO:0002931)
0.0 0.7 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.9 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.5 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.4 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 2.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 1.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.8 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.2 GO:0030882 lipid antigen binding(GO:0030882)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters