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PRJNA207719: Tissue specific transcriptome profiling

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Results for hmx2_hmx3a

Z-value: 1.13

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Transcription factors associated with hmx2_hmx3a

Gene Symbol Gene ID Gene Info
ENSDARG00000070954 H6 family homeobox 2
ENSDARG00000115364 H6 family homeobox 2
ENSDARG00000070955 H6 family homeobox 3a
ENSDARG00000115051 H6 family homeobox 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hmx3adr11_v1_chr17_-_21793113_21793113-0.721.7e-01Click!
hmx2dr11_v1_chr17_-_21784152_21784152-0.089.0e-01Click!

Activity profile of hmx2_hmx3a motif

Sorted Z-values of hmx2_hmx3a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_38301080 1.63 ENSDART00000105672
myosin binding protein C, fast type b
chr5_-_25723079 1.13 ENSDART00000014013
guanine deaminase
chr17_+_50701748 0.54 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermitin family member 2
chr8_-_53166975 0.53 ENSDART00000114683
rabenosyn, RAB effector
chr11_+_36243774 0.41 ENSDART00000023323
zgc:172270
chr8_-_39739627 0.38 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
chr8_-_51293265 0.37 ENSDART00000127875
ENSDART00000181145
bone morphogenetic protein 1a
chr8_-_39739056 0.35 ENSDART00000147992
si:ch211-170d8.5
chr25_-_26018240 0.35 ENSDART00000150800
acyl-CoA synthetase bubblegum family member 1
chr16_-_13516745 0.34 ENSDART00000145410
si:dkeyp-69b9.3
chr1_-_53750522 0.32 ENSDART00000190755
v-akt murine thymoma viral oncogene homolog 3b
chr5_+_37032038 0.32 ENSDART00000045036
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr9_+_30720048 0.31 ENSDART00000146115
Kruppel-like factor 12b
chr25_-_10503043 0.31 ENSDART00000155404
cytochrome c oxidase subunit 8b
chr20_-_40755614 0.31 ENSDART00000061247
connexin 32.3
chr6_+_29410986 0.30 ENSDART00000065293
ubiquitin specific peptidase 13
chr24_-_14711597 0.30 ENSDART00000131830
junctophilin 1a
chr5_-_43959972 0.30 ENSDART00000180517
si:ch211-204c21.1
chr3_+_60721342 0.29 ENSDART00000157772
forkhead box J1a
chr24_-_9997948 0.29 ENSDART00000136274
si:ch211-146l10.7
chr5_+_65157576 0.28 ENSDART00000159599
cilia and flagella associated protein 157
chr21_+_40484088 0.28 ENSDART00000161919
coronin 6
chr18_+_36582815 0.27 ENSDART00000059311
sialic acid acetylesterase
chr25_+_3326885 0.27 ENSDART00000104866
lactate dehydrogenase Bb
chr3_-_26017592 0.27 ENSDART00000030890
heme oxygenase 1a
chr25_+_31267268 0.26 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr10_+_9372702 0.26 ENSDART00000021100
LIM homeobox 6
chr10_-_27046639 0.26 ENSDART00000041841
cornichon family AMPA receptor auxiliary protein 2
chr14_-_33044955 0.25 ENSDART00000170626
kinase insert domain receptor like
chr12_-_3756405 0.25 ENSDART00000150839
family with sequence similarity 57, member Bb
chr15_-_19677511 0.24 ENSDART00000043743
si:dkey-4p15.3
chr8_-_25120231 0.24 ENSDART00000147308
adhesion molecule with Ig-like domain 1
chr18_+_8346920 0.24 ENSDART00000083421
carnitine palmitoyltransferase 1B (muscle)
chr9_-_22821901 0.24 ENSDART00000101711
nebulin
chr8_+_49778756 0.24 ENSDART00000083790
neurotrophic tyrosine kinase, receptor, type 2a
chr2_+_22702488 0.23 ENSDART00000076647
kinesin family member 1Ab
chr23_-_26652273 0.23 ENSDART00000112124
ENSDART00000111029
heparan sulfate proteoglycan 2
chr6_-_23931442 0.23 ENSDART00000160547
SEC16 homolog B, endoplasmic reticulum export factor
chr22_-_24757785 0.23 ENSDART00000078225
vitellogenin 5
chr2_+_47623202 0.22 ENSDART00000154465
si:ch211-165b10.3
chr2_+_56657804 0.22 ENSDART00000113964
RNA polymerase II subunit E
chr18_-_15532016 0.22 ENSDART00000165279
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr18_+_13792490 0.21 ENSDART00000136754
cadherin 13, H-cadherin (heart)
chr8_-_19051906 0.21 ENSDART00000089024
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr10_-_36591511 0.21 ENSDART00000063347
solute carrier family 1 (glial high affinity glutamate transporter), member 3b
chr11_-_4235811 0.20 ENSDART00000121716
si:ch211-236d3.4
chr17_+_45737992 0.20 ENSDART00000135073
ENSDART00000143525
ENSDART00000158165
ENSDART00000184167
ENSDART00000109525
asparaginase homolog (S. cerevisiae)
chr16_-_5873866 0.20 ENSDART00000136936
trafficking protein, kinesin binding 1a
chr5_+_24287927 0.20 ENSDART00000143563
zinc finger, DHHC-type containing 23a
chr2_+_9821757 0.19 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr3_-_35800221 0.19 ENSDART00000031390
CASK interacting protein 1
chr23_-_27345425 0.19 ENSDART00000022042
ENSDART00000191870
sodium channel, voltage gated, type VIII, alpha subunit a
chr24_-_24959607 0.19 ENSDART00000146930
ENSDART00000184482
pyruvate dehydrogenase kinase, isozyme 3a
chr13_+_24280380 0.19 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr17_-_23727978 0.19 ENSDART00000079600
multiple inositol-polyphosphate phosphatase 1a
chr19_-_34873566 0.19 ENSDART00000016057
catenin (cadherin-associated protein), alpha-like 1
chr15_-_18361475 0.19 ENSDART00000155866
zinc finger and BTB domain containing 16b
chr25_-_7683316 0.18 ENSDART00000128820
si:ch211-286c4.6
chr5_+_44806374 0.18 ENSDART00000184237
cathepsin La
chr10_+_21780250 0.18 ENSDART00000183782
protocadherin 1 gamma 9
chr1_-_51465730 0.18 ENSDART00000074284
sprouty-related, EVH1 domain containing 2a
chr5_-_65662996 0.18 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr6_+_11250316 0.18 ENSDART00000137122
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr4_-_6806632 0.18 ENSDART00000139242
interferon-related developmental regulator 1
chr14_-_33454595 0.18 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr7_-_19420334 0.17 ENSDART00000173838
si:ch73-71d17.2
chr8_+_50534948 0.17 ENSDART00000174435
phosphatidylethanolamine binding protein 4
chr16_+_46995398 0.17 ENSDART00000177679
thrombospondin, type I, domain containing 7Ab
chr22_-_7129631 0.17 ENSDART00000171359
acid-sensing (proton-gated) ion channel 1b
chr19_-_5865766 0.17 ENSDART00000191007

chr3_-_40945710 0.17 ENSDART00000138719
ENSDART00000102416
cytochrome P450, family 3, subfamily C, polypeptide 4
chr7_-_26270014 0.16 ENSDART00000079347
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr13_+_15656042 0.16 ENSDART00000134240
MAP/microtubule affinity-regulating kinase 3a
chr20_-_40367493 0.16 ENSDART00000075096
sphingomyelin phosphodiesterase, acid-like 3A
chr11_+_30057762 0.16 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr7_+_3229828 0.16 ENSDART00000135367

chr21_+_9628854 0.16 ENSDART00000161753
ENSDART00000160711
mitogen-activated protein kinase 10
chr13_-_21688176 0.16 ENSDART00000063825
shadow of prion protein
chr3_+_17314997 0.16 ENSDART00000139763
signal transducer and activator of transcription 5a
chr15_-_30857350 0.16 ENSDART00000138988
A kinase (PRKA) anchor protein 1b
chr24_+_25692802 0.16 ENSDART00000190493
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr4_+_25607101 0.16 ENSDART00000133929
acyl-CoA thioesterase 14
chr4_-_10599062 0.16 ENSDART00000048003
tetraspanin 12
chr2_+_37140448 0.16 ENSDART00000045016
ENSDART00000142940
peroxisomal biogenesis factor 19
chr12_+_46605600 0.15 ENSDART00000123533
fatty acid desaturase 6
chr15_+_627619 0.15 ENSDART00000157207
si:ch211-210b2.1
chr6_-_14146979 0.15 ENSDART00000089564
calcium channel, voltage-dependent, beta 4b subunit
chr10_+_14963898 0.15 ENSDART00000187363
ENSDART00000175732
si:dkey-88l16.3
chr18_-_8313686 0.15 ENSDART00000182187
mitogen-activated protein kinase 8 interacting protein 2
chr21_+_44857293 0.15 ENSDART00000134365
ENSDART00000168217
ENSDART00000065083
follistatin-like 4
chr19_-_31522625 0.15 ENSDART00000158438
ENSDART00000035049
N-terminal EF-hand calcium binding protein 1
chr23_+_20803270 0.15 ENSDART00000097381
zgc:154075
chr14_+_15155684 0.14 ENSDART00000167966
zgc:158852
chr4_+_25607743 0.14 ENSDART00000028297
acyl-CoA thioesterase 14
chr16_+_28932038 0.14 ENSDART00000149480
natriuretic peptide receptor 1b
chr1_+_22002649 0.14 ENSDART00000141317
dynein, axonemal, heavy chain 6
chr16_-_45854882 0.14 ENSDART00000027013
ENSDART00000128068
neurotrophic tyrosine kinase, receptor, type 1
chr13_+_681628 0.14 ENSDART00000016604
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_-_4461104 0.14 ENSDART00000023090
ENSDART00000140770
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr23_+_21424747 0.14 ENSDART00000135440
ENSDART00000104214
taste receptor, type 1, member 1
chr9_-_22822084 0.14 ENSDART00000142020
nebulin
chr11_+_37178271 0.14 ENSDART00000161771
inter-alpha-trypsin inhibitor heavy chain 3b
chr14_+_29581710 0.14 ENSDART00000188820
ENSDART00000193874
si:dkey-34l15.2
chr16_-_2818170 0.14 ENSDART00000081918
acyl-CoA thioesterase 22
chr24_+_5912635 0.13 ENSDART00000153736
Pim proto-oncogene, serine/threonine kinase, related 63
chr17_+_15433518 0.13 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr5_+_19314574 0.13 ENSDART00000133247
RUN and SH3 domain containing 2
chr23_-_39784368 0.13 ENSDART00000110282
si:ch211-286f9.2
chr20_-_1174266 0.13 ENSDART00000023304
gamma-aminobutyric acid (GABA) A receptor, rho 2b
chr1_+_54908895 0.13 ENSDART00000145652
golgin A7 family, member Ba
chr5_+_31036911 0.13 ENSDART00000141463
ENSDART00000162121
zinc finger, ZZ-type with EF hand domain 1
chr17_+_15433671 0.13 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr9_+_24106469 0.13 ENSDART00000039295
leucine rich repeat (in FLII) interacting protein 1a
chr11_-_34628789 0.13 ENSDART00000192433
mitogen-activated protein kinase-activated protein kinase 3
chr21_-_23307653 0.13 ENSDART00000140284
ENSDART00000134103
zinc finger and BTB domain containing 16a
chr2_+_20332044 0.13 ENSDART00000112131
phospholipid phosphatase related 4a
chr17_-_1407593 0.13 ENSDART00000157622
ENSDART00000159458
zinc finger and BTB domain containing 42
chr25_+_13498188 0.13 ENSDART00000015710
SNF related kinase b
chr13_+_2894536 0.13 ENSDART00000183678

chr16_-_28268201 0.13 ENSDART00000121671
ENSDART00000141911
si:dkey-12j5.1
chr9_-_48397702 0.13 ENSDART00000147169
zgc:172182
chr25_+_3327071 0.13 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr9_-_14273652 0.12 ENSDART00000135458
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr9_-_390874 0.12 ENSDART00000165324
si:dkey-11f4.7
chr16_+_28881235 0.12 ENSDART00000146525
chromatin target of PRMT1b
chr12_+_1139690 0.12 ENSDART00000160442

chr18_+_41495841 0.12 ENSDART00000098671
si:ch211-203b8.6
chr1_-_25966068 0.12 ENSDART00000137869
ENSDART00000134192
synaptopodin 2b
chr2_-_47431205 0.12 ENSDART00000014350
ENSDART00000038828
paired box 3a
chr5_+_38913621 0.12 ENSDART00000137112
Fraser extracellular matrix complex subunit 1
chr4_-_16824231 0.12 ENSDART00000014007
glycogen synthase 2
chr18_-_7677208 0.12 ENSDART00000092456
SH3 and multiple ankyrin repeat domains 3a
chr13_+_30169681 0.12 ENSDART00000138326
phosphatase domain containing, paladin 1b
chr15_-_33172246 0.12 ENSDART00000158666
neurobeachin b
chr13_-_29421331 0.12 ENSDART00000150228
choline O-acetyltransferase a
chr11_-_1509773 0.12 ENSDART00000050762
phosphatase and actin regulator 3b
chr3_-_50177658 0.12 ENSDART00000135309
zgc:114118
chr10_+_33406819 0.12 ENSDART00000137089
ryanodine receptor 1a (skeletal)
chr3_-_40965328 0.12 ENSDART00000102393
cytochrome P450, family 3, subfamily c, polypeptide 2
chr23_+_10469955 0.12 ENSDART00000140557
tensin 2a
chr13_+_41917606 0.12 ENSDART00000114741
polymerase (RNA) I polypeptide B
chr2_+_24304854 0.12 ENSDART00000078972
fat storage-inducing transmembrane protein 1
chr12_+_34953038 0.11 ENSDART00000187022
ENSDART00000123988
ENSDART00000027034
QKI, KH domain containing, RNA binding 2
chr18_+_14564085 0.11 ENSDART00000009363
ENSDART00000141813
ENSDART00000136120
si:dkey-246g23.4
chr15_+_478524 0.11 ENSDART00000018062
si:ch1073-280e3.1
chr1_-_38709551 0.11 ENSDART00000128794
glycoprotein M6Ab
chr23_+_9353552 0.11 ENSDART00000163298

chr6_+_8315050 0.11 ENSDART00000189987
glutaryl-CoA dehydrogenase a
chr1_+_45085194 0.11 ENSDART00000193863
si:ch211-151p13.8
chr9_+_40939336 0.11 ENSDART00000100386
myostatin b
chr18_+_1145571 0.11 ENSDART00000135055
REC114 meiotic recombination protein
chr21_-_19314618 0.11 ENSDART00000188744
glycerol-3-phosphate acyltransferase 3
chr5_-_12407194 0.11 ENSDART00000125291
kinase suppressor of ras 2
chr11_-_41966854 0.11 ENSDART00000055709
hairy-related 2
chr3_+_54761569 0.11 ENSDART00000135913
ENSDART00000180983
si:ch211-74m13.1
chr8_+_42941555 0.11 ENSDART00000183206
solute carrier family 23 (ascorbic acid transporter), member 2
chr8_-_14375890 0.11 ENSDART00000090306
xenotropic and polytropic retrovirus receptor 1a
chr21_-_14803366 0.11 ENSDART00000190872
si:dkey-11o18.5
chr1_-_53407448 0.11 ENSDART00000160033
ENSDART00000172322
ELMO/CED-12 domain containing 2
chr3_-_40965596 0.11 ENSDART00000137188
cytochrome P450, family 3, subfamily c, polypeptide 2
chr23_+_26946744 0.11 ENSDART00000115141
calcium channel, voltage-dependent, beta 3b
chr11_-_23332592 0.11 ENSDART00000125024
golgi transport 1A
chr21_+_39197628 0.11 ENSDART00000113607
carboxypeptidase D, b
chr7_-_24005268 0.11 ENSDART00000173608
si:dkey-183c6.9
chr10_-_43392267 0.11 ENSDART00000142872
EGF-like repeats and discoidin I-like domains 3b
chr5_-_7834582 0.11 ENSDART00000162626
ENSDART00000157661
PDZ and LIM domain 5a
chr8_+_41035230 0.10 ENSDART00000141349
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr4_-_1720648 0.10 ENSDART00000103484
growth arrest-specific 2 like 3
chr24_+_5912898 0.10 ENSDART00000132686
Pim proto-oncogene, serine/threonine kinase, related 63
chr22_-_20289948 0.10 ENSDART00000132951
si:dkey-110c1.10
chr22_+_9027884 0.10 ENSDART00000171839
si:ch211-213a13.2
chr15_+_45563656 0.10 ENSDART00000157501
claudin 15-like b
chr24_-_6898302 0.10 ENSDART00000158646
dipeptidyl-peptidase 6a
chr4_+_4267451 0.10 ENSDART00000192069
anoctamin 2
chr24_-_16904803 0.10 ENSDART00000165972
ENSDART00000149974
ENSDART00000149706
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr20_-_8443425 0.10 ENSDART00000083908
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr24_-_5911973 0.10 ENSDART00000077933
ENSDART00000077922
Pim proto-oncogene, serine/threonine kinase, related 64
chr16_-_33816082 0.10 ENSDART00000181769
R-spondin 1
chr4_-_11751037 0.10 ENSDART00000102301
podocalyxin-like
chr24_-_16905018 0.10 ENSDART00000066759
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr1_-_19845378 0.10 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
glyoxylate reductase/hydroxypyruvate reductase b
chr12_+_24561832 0.10 ENSDART00000088159
neurexin 1a
chr20_+_34717403 0.10 ENSDART00000034252
prepronociceptin b
chr25_-_3469576 0.10 ENSDART00000186738
HMG-box transcription factor 1
chr3_+_22059066 0.10 ENSDART00000155739
KAT8 regulatory NSL complex subunit 1b
chr21_+_45502773 0.10 ENSDART00000160059
ENSDART00000165704
si:dkey-223p19.2
chr19_+_31532043 0.10 ENSDART00000136289
transmembrane protein 64
chr18_+_45573251 0.10 ENSDART00000191309
kinesin family member C3
chr15_-_21014270 0.10 ENSDART00000154019
si:ch211-212c13.10
chr8_+_38415374 0.10 ENSDART00000085395
NK6 homeobox 3
chr15_-_21155641 0.10 ENSDART00000061098
ENSDART00000046443
si:dkey-105h12.2
chr10_+_45089820 0.10 ENSDART00000175481
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr15_+_14856307 0.10 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr1_-_29758947 0.10 ENSDART00000049514
ENSDART00000183571
ENSDART00000140345
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr14_-_46213571 0.10 ENSDART00000056734
SET domain containing (lysine methyltransferase) 7
chr1_+_53321878 0.10 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr25_-_19433244 0.10 ENSDART00000154778
microtubule-associated protein 1Ab
chr7_+_13382852 0.09 ENSDART00000166318
diacylglycerol lipase, alpha
chr13_+_23176330 0.09 ENSDART00000168351
sorbin and SH3 domain containing 1
chr23_+_19675780 0.09 ENSDART00000124335
small integral membrane protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of hmx2_hmx3a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.3 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.1 0.2 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.3 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.4 GO:0032964 collagen biosynthetic process(GO:0032964)
0.1 0.2 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.2 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:1901862 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0 0.1 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.3 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.2 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0060958 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 0.2 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.1 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.1 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.0 0.1 GO:0051503 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.1 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.0 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
0.0 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.2 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.0 GO:0021985 neurohypophysis development(GO:0021985)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.2 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.0 0.1 GO:0016122 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.4 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.0 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.0 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.1 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.1 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0006570 tyrosine metabolic process(GO:0006570)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.2 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.2 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.3 GO:0008126 acetylesterase activity(GO:0008126)
0.0 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.2 GO:0004067 asparaginase activity(GO:0004067)
0.0 0.1 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0038046 enkephalin receptor activity(GO:0038046)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 1.1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.0 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:1901612 cardiolipin binding(GO:1901612)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle