Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation
Downloads

Results for hoxa13a+hoxa13b

Z-value: 1.20

Motif logo

Transcription factors associated with hoxa13a+hoxa13b

Gene Symbol Gene ID Gene Info
ENSDARG00000036254 homeobox A13b
ENSDARG00000100312 homeobox A13a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa13bdr11_v1_chr16_+_20895904_20895904-0.148.2e-01Click!
hoxa13adr11_v1_chr19_+_19729506_19729506-0.128.5e-01Click!

Activity profile of hoxa13a+hoxa13b motif

Sorted Z-values of hoxa13a+hoxa13b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_26612321 0.91 ENSDART00000134322
four and a half LIM domains 1b
chr11_-_30611814 0.64 ENSDART00000089803
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr2_-_24289641 0.60 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myosin heavy chain 7-like
chr24_-_39826865 0.59 ENSDART00000089232
solute carrier family 12 (potassium/chloride transporter), member 7b
chr11_-_18253111 0.49 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr5_+_21211135 0.48 ENSDART00000088492
bone morphogenetic protein 10
chr1_+_55140970 0.46 ENSDART00000039807
myoglobin
chr23_+_18722715 0.44 ENSDART00000137438
myosin, heavy chain 7B, cardiac muscle, beta b
chr10_+_17026870 0.43 ENSDART00000184529
ENSDART00000157480

chr23_+_18722915 0.42 ENSDART00000025057
myosin, heavy chain 7B, cardiac muscle, beta b
chr7_-_16562200 0.42 ENSDART00000169093
ENSDART00000173491
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr23_+_7379728 0.41 ENSDART00000012194
GATA binding protein 5
chr4_+_7391400 0.40 ENSDART00000169111
ENSDART00000186395
troponin I4a
chr22_+_15624371 0.37 ENSDART00000124868
lipoprotein lipase
chr16_-_45917322 0.37 ENSDART00000060822
antifreeze protein type IV
chr4_-_2380173 0.37 ENSDART00000177727
nucleosome assembly protein 1-like 1
chr12_-_20373058 0.36 ENSDART00000066382
aquaporin 8a, tandem duplicate 1
chr16_-_21785261 0.35 ENSDART00000078858
si:ch73-86n18.1
chr5_-_42272517 0.35 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
chr13_+_23132666 0.35 ENSDART00000164639
sorbin and SH3 domain containing 1
chr13_+_844150 0.34 ENSDART00000058260
glutathione S-transferase, alpha tandem duplicate 1
chr13_-_37619159 0.34 ENSDART00000186348
zgc:152791
chr4_+_7391110 0.34 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr21_-_25756119 0.33 ENSDART00000002341
claudin c
chr11_+_24314148 0.33 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr11_+_24313931 0.32 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr6_+_43450221 0.32 ENSDART00000075521
zgc:113054
chr23_+_42810055 0.32 ENSDART00000186647
myosin, light chain 9a, regulatory
chr15_+_14856307 0.32 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr6_-_15101477 0.30 ENSDART00000187713
ENSDART00000124132
four and a half LIM domains 2b
chr7_-_69025306 0.30 ENSDART00000180796

chr18_+_7151783 0.30 ENSDART00000134872
von Willebrand factor
chr14_-_21123551 0.29 ENSDART00000171679
ENSDART00000165882
si:dkey-74k8.4
chr2_+_52232630 0.28 ENSDART00000006216
phospholipid phosphatase 2a
chr23_+_17417539 0.28 ENSDART00000182605

chr14_+_36738069 0.28 ENSDART00000105590
tryptophan 2,3-dioxygenase a
chr6_+_13201358 0.27 ENSDART00000190290

chr13_+_37022601 0.27 ENSDART00000131800
ENSDART00000041300
estrogen receptor 2b
chr10_-_21545091 0.27 ENSDART00000029122
ENSDART00000132207
zgc:165539
chr17_+_53294228 0.26 ENSDART00000158172
si:ch1073-416d2.3
chr10_+_22775253 0.26 ENSDART00000190141
transmembrane protein 88 a
chr17_-_50022827 0.26 ENSDART00000161008
filamin A interacting protein 1a
chr12_+_27704015 0.25 ENSDART00000153256
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr15_-_21132480 0.25 ENSDART00000078734
ENSDART00000157481
alpha-2-macroglobulin-like
chr9_-_32300611 0.25 ENSDART00000127938
heat shock 60 protein 1
chr24_-_36723116 0.24 ENSDART00000088204
si:ch73-334d15.1
chr23_+_1078072 0.24 ENSDART00000159263
ENSDART00000053527
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2b
chr8_-_19280856 0.24 ENSDART00000100473
zgc:77486
chr20_+_25586099 0.24 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr19_+_20778011 0.24 ENSDART00000024208
nuclear transport factor 2, like
chr24_+_21640635 0.24 ENSDART00000105925
general transcription factor IIIA, b
chr21_-_2707768 0.24 ENSDART00000165384

chr9_-_32300783 0.23 ENSDART00000078596
heat shock 60 protein 1
chr24_+_1042594 0.23 ENSDART00000109117
si:dkey-192l18.9
chr8_+_30709685 0.23 ENSDART00000133989
ureidopropionase, beta
chr8_+_40477264 0.23 ENSDART00000085559
glucokinase (hexokinase 4)
chr10_-_1276046 0.22 ENSDART00000169779
PDZ and LIM domain 5b
chr1_-_33647138 0.22 ENSDART00000142111
ENSDART00000015547
claudin g
chr25_+_34641536 0.22 ENSDART00000167033

chr17_+_15788100 0.22 ENSDART00000027667
ras-related GTP binding D
chr7_+_48761646 0.22 ENSDART00000017467
aggrecan a
chr7_+_67429185 0.22 ENSDART00000162553
ENSDART00000178646
lysyl-tRNA synthetase
chr16_+_23921610 0.21 ENSDART00000143855
apolipoprotein A-IV b, tandem duplicate 3
chr10_-_22803740 0.21 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
procollagen C-endopeptidase enhancer a
chr16_-_33001153 0.20 ENSDART00000147941
malic enzyme 1, NADP(+)-dependent, cytosolic
chr2_+_16781015 0.20 ENSDART00000155147
ENSDART00000003845
transferrin-a
chr7_+_48761875 0.20 ENSDART00000003690
aggrecan a
chr5_+_1493767 0.20 ENSDART00000022132
HAUS augmin-like complex, subunit 4
chr16_+_16826504 0.20 ENSDART00000108691
potassium inwardly-rectifying channel, subfamily J, member 14
chr3_-_60316118 0.20 ENSDART00000171458
si:ch211-214b16.2
chr22_-_38819603 0.20 ENSDART00000104437
si:ch211-262h13.5
chr20_-_25533739 0.20 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr21_-_20840714 0.19 ENSDART00000144861
ENSDART00000139430
complement component 6
chr9_+_32301017 0.19 ENSDART00000127916
ENSDART00000183298
ENSDART00000143103
heat shock 10 protein 1
chr11_-_16394971 0.19 ENSDART00000180981
ENSDART00000179925
leucine-rich repeats and immunoglobulin-like domains 1
chr23_+_17865953 0.19 ENSDART00000014723
ENSDART00000140302
ENSDART00000144800
nascent polypeptide-associated complex alpha subunit
chr11_-_45185792 0.19 ENSDART00000171328
si:dkey-93h22.7
chr20_+_40150612 0.19 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
triadin
chr2_+_16780643 0.19 ENSDART00000125647
ENSDART00000108611
ENSDART00000181245
ENSDART00000163194
transferrin-a
chr16_-_17300030 0.19 ENSDART00000149267
Kell blood group, metallo-endopeptidase
chr21_-_27195256 0.19 ENSDART00000133152
ENSDART00000065401
zgc:110782
chr21_+_13301798 0.19 ENSDART00000140206
adenosine A2a receptor b
chr10_-_35410518 0.19 ENSDART00000048430
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr8_-_18899427 0.19 ENSDART00000079840
RAR-related orphan receptor C a
chr21_+_5531138 0.19 ENSDART00000163825
lymphocyte antigen 6 family member M6
chr3_+_1005059 0.18 ENSDART00000132460
zgc:172051
chr13_+_7442023 0.18 ENSDART00000080975
tumor necrosis factor, alpha-induced protein 2b
chr7_+_37372479 0.18 ENSDART00000173652
spalt-like transcription factor 1a
chr18_+_35861930 0.18 ENSDART00000185223
protein phosphatase 1, regulatory subunit 13 like
chr5_-_42883761 0.18 ENSDART00000167374

chr7_+_48555400 0.18 ENSDART00000174474
potassium voltage-gated channel, KQT-like subfamily, member 1
chr10_+_41199660 0.18 ENSDART00000125314
adrenoceptor beta 3b
chr1_-_9249943 0.17 ENSDART00000055011
zgc:136472
chr7_-_39537292 0.17 ENSDART00000173965
otogelin
chr13_-_35892243 0.17 ENSDART00000002750
ENSDART00000122810
ENSDART00000162399
transforming, acidic coiled-coil containing protein 3
chr5_-_42071505 0.17 ENSDART00000137224
ENSDART00000193721
chemokine (C-X-C motif) ligand 11, duplicate 7
centromere protein V
chr6_-_53426773 0.17 ENSDART00000162791
macrophage stimulating 1
chr15_+_17030941 0.17 ENSDART00000062069
perilipin 2
chr20_+_48116476 0.17 ENSDART00000043938
translocation associated membrane protein 2
chr7_+_33132074 0.17 ENSDART00000073554
zgc:153219
chr11_-_25418856 0.17 ENSDART00000013714
GATA binding protein 1a
chr6_-_33916756 0.17 ENSDART00000137447
ENSDART00000138488
nuclear autoantigenic sperm protein (histone-binding)
chr5_-_33281046 0.17 ENSDART00000051344
ENSDART00000138116
surfeit 6
chr20_+_51199666 0.17 ENSDART00000169321
heat shock protein 90, alpha (cytosolic), class B member 1
chr2_-_54639964 0.16 ENSDART00000100103
acyl-CoA synthetase short chain family member 2 like
chr15_-_34567370 0.16 ENSDART00000099793
sclerostin domain containing 1a
chr18_-_10713230 0.16 ENSDART00000183646
RNA binding motif protein 28
chr7_-_30367650 0.16 ENSDART00000075519
aldehyde dehydrogenase 1 family, member A2
chr19_-_42557416 0.16 ENSDART00000163217
ENSDART00000128278
ENSDART00000162304
ENSDART00000166556
si:dkey-267n13.1
chr20_-_30369598 0.16 ENSDART00000144549
allantoicase
chr13_+_24584401 0.16 ENSDART00000057599
fucose mutarotase
chr9_+_426392 0.16 ENSDART00000172515
basic leucine zipper and W2 domains 1b
chr16_+_50969248 0.16 ENSDART00000172068
si:dkeyp-97a10.2
chr17_-_50020672 0.16 ENSDART00000188942
filamin A interacting protein 1a
chr4_-_77331797 0.16 ENSDART00000162325
solute carrier organic anion transporter family, member 1F3
chr11_+_13223625 0.16 ENSDART00000161275
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr4_+_77981553 0.16 ENSDART00000174108
ENSDART00000122459
telomeric repeat binding factor a
chr17_-_2690083 0.16 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr3_+_46764278 0.15 ENSDART00000136051
ENSDART00000164930
protein kinase C substrate 80K-H
chr20_+_32501748 0.15 ENSDART00000152944
ENSDART00000021035
SEC63 homolog, protein translocation regulator
chr19_+_17385561 0.15 ENSDART00000141397
ENSDART00000143913
ENSDART00000133626
ribosomal protein L15
chr11_-_24016761 0.15 ENSDART00000153601
ENSDART00000067817
ENSDART00000170531
chitinase, acidic.3
chr10_+_35526528 0.15 ENSDART00000184110
pleckstrin homology-like domain, family B, member 2a
chr24_+_7782313 0.15 ENSDART00000111090
protein tyrosine phosphatase, receptor type, h
chr16_-_563235 0.15 ENSDART00000016303
iroquois homeobox 2a
chr25_+_9003230 0.15 ENSDART00000180330
ENSDART00000142917
recombination activating gene 1
chr1_-_58562129 0.15 ENSDART00000159070
solute carrier family 27 (fatty acid transporter), member 1b
chr7_+_34592526 0.15 ENSDART00000173959
formin homology 2 domain containing 1
chr22_+_10781894 0.15 ENSDART00000081183
ectodermal-neural cortex 3
chr13_-_36844945 0.15 ENSDART00000129562
ENSDART00000150899
ninein (GSK3B interacting protein)
chr21_-_26114886 0.15 ENSDART00000139320
NIPA-like domain containing 4
chr2_+_45548890 0.15 ENSDART00000113994
fibronectin type III domain containing 7a
chr15_+_45586471 0.15 ENSDART00000165699
claudin 15-like b
chr2_+_25315591 0.15 ENSDART00000161386
fibronectin type III domain containing 3Ba
chr17_+_7513673 0.14 ENSDART00000156674
kelch-like family member 10b, tandem duplicate 1
chr4_-_16836006 0.14 ENSDART00000010777
lactate dehydrogenase Ba
chr16_-_560574 0.14 ENSDART00000148452
iroquois homeobox 2a
chr21_-_17290941 0.14 ENSDART00000147993
growth factor independent 1B transcription repressor
chr10_+_14963898 0.14 ENSDART00000187363
ENSDART00000175732
si:dkey-88l16.3
chr18_+_46151505 0.14 ENSDART00000015034
ENSDART00000141287
biliverdin reductase B
chr20_+_52546186 0.14 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr25_+_5035343 0.14 ENSDART00000011751
parvin, beta
chr2_+_21048661 0.14 ENSDART00000156876
ras responsive element binding protein 1b
chr24_-_23671383 0.14 ENSDART00000144193
hepatocyte nuclear factor 4, gamma
chr14_+_36886950 0.14 ENSDART00000183719
si:ch211-132p1.3
chr9_+_41080029 0.14 ENSDART00000141179
ENSDART00000019289
zgc:136439
chr1_-_35924495 0.14 ENSDART00000184424
SMAD family member 1
chr5_-_68244564 0.14 ENSDART00000169350

chr2_+_10147029 0.14 ENSDART00000139064
ENSDART00000053426
ENSDART00000153678
profilin 2 like
chr7_-_23777445 0.14 ENSDART00000173527
si:ch211-200p22.4
chr25_+_13620555 0.14 ENSDART00000163642
si:ch211-172l8.4
chr12_+_27231607 0.14 ENSDART00000066270
transmembrane protein 106A
chr20_-_25522911 0.14 ENSDART00000063058
cytochrome P450, family 2, subfamily N, polypeptide 13
chr25_-_24046870 0.14 ENSDART00000047569
insulin-like growth factor 2b
chr19_-_24555623 0.14 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr8_+_40476811 0.14 ENSDART00000129772
glucokinase (hexokinase 4)
chr21_+_20396858 0.14 ENSDART00000003299
ENSDART00000146615
zgc:103482
chr25_-_15040369 0.13 ENSDART00000159342
ENSDART00000166490
paired box 6a
chr2_-_30182353 0.13 ENSDART00000019149
ribosomal protein L7
chr2_+_49457626 0.13 ENSDART00000129967
SH3-domain GRB2-like 1a
chr11_+_25539698 0.13 ENSDART00000035602
CXXC finger protein 1b
chr9_-_38036984 0.13 ENSDART00000134574
3-hydroxyacyl-CoA dehydratase 2
chr5_-_23200880 0.13 ENSDART00000051531
IQ motif containing D
chr6_-_52348562 0.13 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eukaryotic translation initiation factor 6
chr5_-_34993242 0.13 ENSDART00000134516
ENSDART00000051295
basic transcription factor 3
chr2_-_50225411 0.13 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr4_+_31293362 0.13 ENSDART00000169781
si:dkey-57l19.1
chr16_+_11992498 0.13 ENSDART00000143442
prolyl 3-hydroxylase 3
chr18_+_619619 0.13 ENSDART00000159846
protogenin homolog a (Gallus gallus)
chr25_+_336503 0.13 ENSDART00000160395

chr1_+_44395976 0.13 ENSDART00000159686
ENSDART00000189905
ENSDART00000025145
unc-93 homolog B1, TLR signaling regulator
chr24_+_21621654 0.13 ENSDART00000002595
ribosomal protein L21
chr22_+_6674992 0.13 ENSDART00000144054
si:ch211-209l18.2
chr16_-_7793457 0.13 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr6_+_52804267 0.13 ENSDART00000065681
matrilin 4
chr14_-_15171435 0.13 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
chr2_-_10877765 0.13 ENSDART00000100607
cell division cycle 7 homolog (S. cerevisiae)
chr6_-_12588044 0.13 ENSDART00000047896
solute carrier family 15 (oligopeptide transporter), member 1b
chr23_+_39963599 0.12 ENSDART00000166539
FYVE and coiled-coil domain containing 1a
chr1_+_51827046 0.12 ENSDART00000052992
DAN domain family, member 5
chr1_+_12177195 0.12 ENSDART00000146842
ENSDART00000142081
STRA6-like
chr14_+_26247319 0.12 ENSDART00000192793
coiled-coil domain containing 69
chr11_-_44484952 0.12 ENSDART00000166674
ENSDART00000188016
mitofusin 1b
chr11_-_25539323 0.12 ENSDART00000155785
si:dkey-245f22.3
chr9_+_22364997 0.12 ENSDART00000188054
ENSDART00000046116
crystallin, gamma S3
chr16_+_29509133 0.12 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr16_+_42464613 0.12 ENSDART00000162454
si:ch211-215k15.4
chr12_+_19199735 0.12 ENSDART00000066393
pdgfa associated protein 1a
chr7_+_38507006 0.12 ENSDART00000173830
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr23_+_37482727 0.12 ENSDART00000162737
agmatine ureohydrolase (agmatinase)
chr18_+_40462445 0.12 ENSDART00000087645
UDP glucuronosyltransferase 5 family, polypeptide C2
chr2_+_49457449 0.12 ENSDART00000185470
SH3-domain GRB2-like 1a
chr1_+_47486104 0.12 ENSDART00000114746
leucine rich repeat containing 58a
chr9_+_27348809 0.12 ENSDART00000147540
toll-like receptor 20, tandem duplicate 1
chr7_+_58751504 0.12 ENSDART00000024185
zgc:56231
chr4_-_73190246 0.12 ENSDART00000170842

chr18_+_6558146 0.12 ENSDART00000169401
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr6_-_46768040 0.12 ENSDART00000154071
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 2
chr1_-_26664840 0.12 ENSDART00000102500
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr13_+_30692669 0.12 ENSDART00000187818

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa13a+hoxa13b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 0.6 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.4 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.4 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.3 GO:0061317 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.1 0.4 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.4 GO:1990798 pancreas regeneration(GO:1990798)
0.1 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.3 GO:0071072 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.2 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 0.2 GO:0071635 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.2 GO:0000256 allantoin catabolic process(GO:0000256)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816)
0.0 0.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0034154 toll-like receptor 3 signaling pathway(GO:0034138) toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.2 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.7 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0030237 female sex determination(GO:0030237)
0.0 0.1 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0033512 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.2 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.1 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.0 0.1 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.0 GO:0003097 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.0 0.5 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.3 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.0 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.5 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0033151 V(D)J recombination(GO:0033151)
0.0 0.1 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.0 GO:0021563 glossopharyngeal nerve development(GO:0021563) adenohypophysis morphogenesis(GO:0048855)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.0 GO:1903961 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.0 0.1 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.0 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.0 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.0 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.0 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.1 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0006833 water transport(GO:0006833) fluid transport(GO:0042044)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.4 GO:0001878 response to yeast(GO:0001878)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.2 GO:0097519 DNA recombinase complex(GO:0097519)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.1 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.3 GO:1903924 estradiol binding(GO:1903924)
0.0 0.2 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0031704 apelin receptor binding(GO:0031704)
0.0 0.7 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.6 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.0 0.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.0 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.1 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions