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PRJNA207719: Tissue specific transcriptome profiling

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Results for hoxc12a+hoxc12b

Z-value: 1.13

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Transcription factors associated with hoxc12a+hoxc12b

Gene Symbol Gene ID Gene Info
ENSDARG00000070352 homeobox C12a
ENSDARG00000103133 homeobox C12b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc12bdr11_v1_chr11_+_2172335_21723350.922.9e-02Click!
hoxc12adr11_v1_chr23_+_36063599_36063599-0.523.7e-01Click!

Activity profile of hoxc12a+hoxc12b motif

Sorted Z-values of hoxc12a+hoxc12b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_35691889 1.21 ENSDART00000074685
glycine receptor, beta b
chr21_-_19018455 1.04 ENSDART00000080256
neurofilament, medium polypeptide a
chr23_-_4855122 0.98 ENSDART00000133701
solute carrier family 6 (neurotransmitter transporter), member 1a
chr24_-_40009446 0.97 ENSDART00000087422
amine oxidase, copper containing 1
chr21_+_13861589 0.94 ENSDART00000015629
ENSDART00000171306
syntaxin binding protein 1a
chr25_-_11057753 0.94 ENSDART00000186551
synaptic vesicle glycoprotein 2Bb
chr8_-_14049404 0.94 ENSDART00000093117
ATPase plasma membrane Ca2+ transporting 3a
chr21_-_4032650 0.94 ENSDART00000151648
netrin g2b
chr1_-_8101495 0.81 ENSDART00000161938
si:dkeyp-9d4.3
chr1_+_36437585 0.79 ENSDART00000189182
POU class 4 homeobox 2
chr20_-_47422469 0.72 ENSDART00000021341
kinesin family member 3Ca
chr23_-_12015139 0.70 ENSDART00000110627
ENSDART00000193988
ENSDART00000184528
si:dkey-178k16.1
chr24_-_38374744 0.69 ENSDART00000007208
leucine rich repeat containing 4Bb
chr19_-_10243148 0.69 ENSDART00000148073
shisa family member 7
chr10_+_21776911 0.68 ENSDART00000163077
ENSDART00000186093
protocadherin 1 gamma 22
chr25_+_21176937 0.68 ENSDART00000163751
ENSDART00000188930
ENSDART00000187155
ELKS/RAB6-interacting/CAST family member 1a
chr3_-_27868183 0.68 ENSDART00000185812
4-aminobutyrate aminotransferase
chr4_+_20318127 0.67 ENSDART00000028856
ENSDART00000132909
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr1_-_26782573 0.66 ENSDART00000090611
SH3 domain containing GRB2 like 2a, endophilin A1
chr8_-_19649617 0.64 ENSDART00000189033
family with sequence similarity 78, member B b
chr6_+_49412754 0.63 ENSDART00000027398
potassium voltage-gated channel, shaker-related subfamily, member 2a
chr15_-_19250543 0.61 ENSDART00000092705
ENSDART00000138895
immunoglobulin superfamily, member 9Ba
chr24_-_6898302 0.58 ENSDART00000158646
dipeptidyl-peptidase 6a
chr25_-_7999756 0.57 ENSDART00000159908
calcium/calmodulin-dependent protein kinase 1Db
chr21_+_20715020 0.57 ENSDART00000015224
growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1
chr23_-_12014931 0.55 ENSDART00000134652
si:dkey-178k16.1
chr7_-_43840418 0.55 ENSDART00000174592
cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_+_36611128 0.54 ENSDART00000097684
neuro-oncological ventral antigen 1
chr7_-_23996133 0.54 ENSDART00000173761
si:dkey-183c6.8
chr23_-_28025943 0.53 ENSDART00000181146
Sp5 transcription factor-like
chr4_-_13156971 0.53 ENSDART00000182164
glutamate receptor interacting protein 1
chr10_-_31805923 0.53 ENSDART00000077785
vacuolar protein sorting 26 homolog B, like
chr7_+_20966434 0.53 ENSDART00000185570
ephrin-B3b
chr9_+_22634073 0.52 ENSDART00000181822
ets variant 5a
chr13_-_24447332 0.51 ENSDART00000043004
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr17_-_23727978 0.49 ENSDART00000079600
multiple inositol-polyphosphate phosphatase 1a
chr10_+_15967643 0.49 ENSDART00000136709
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr7_+_27898091 0.49 ENSDART00000186451
ENSDART00000173510
tubby bipartite transcription factor
chr11_+_42730639 0.47 ENSDART00000165297
zgc:194981
chr6_-_53334259 0.46 ENSDART00000172465
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr18_-_2433011 0.45 ENSDART00000181922
ENSDART00000193276

chr20_-_44576949 0.45 ENSDART00000148639
UBX domain protein 2A
chr5_-_31856681 0.44 ENSDART00000187817
protein kinase N3
chr1_-_22834824 0.44 ENSDART00000043556
LIM domain binding 2b
chr25_+_7670683 0.44 ENSDART00000040275
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr15_-_39820491 0.44 ENSDART00000097134
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_+_21660447 0.43 ENSDART00000164519
protocadherin 1 gamma 3
chr5_-_21065094 0.42 ENSDART00000143785
si:dkey-13n15.2
chr14_-_48348973 0.42 ENSDART00000185822

chr5_-_51819027 0.42 ENSDART00000164267
homer scaffolding protein 1b
chr18_+_31280984 0.41 ENSDART00000170285
ENSDART00000150608
ENSDART00000159720
differentially expressed in FDCP 8 homolog (mouse)
chr14_+_32022272 0.41 ENSDART00000105760
zic family member 6
chr23_-_39849155 0.39 ENSDART00000115330
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr15_+_44093286 0.38 ENSDART00000114352
zgc:112998
chr12_-_48552716 0.38 ENSDART00000063438
Danio rerio testis expressed 47 (tex47), mRNA.
chr11_+_43751263 0.38 ENSDART00000163843
zgc:153431
chr7_-_32833153 0.38 ENSDART00000099871
ENSDART00000099872
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr6_-_53281518 0.37 ENSDART00000157621
RNA binding motif protein 5
chr16_+_5184402 0.36 ENSDART00000156685
SOGA family member 3a
chr2_-_39759059 0.36 ENSDART00000007333
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr15_-_14552101 0.35 ENSDART00000171169
numb homolog (Drosophila)-like
chr22_-_31517300 0.34 ENSDART00000164799
solute carrier family 6 (neurotransmitter transporter), member 6b
chr25_-_18002937 0.34 ENSDART00000149696
centrosomal protein 290
chr1_-_7894255 0.33 ENSDART00000167126
ENSDART00000145460
Ras association and DIL domains
chr20_+_48803248 0.33 ENSDART00000164006
NK2 homeobox 4b
chr3_+_24190207 0.33 ENSDART00000034762
proline rich 15-like a
chr6_+_2174082 0.32 ENSDART00000073936
activin A receptor type 1Bb
chr7_+_59739164 0.32 ENSDART00000110412
G protein-coupled receptor 78b
chr14_-_31060082 0.32 ENSDART00000111601
ENSDART00000161113
muscleblind-like splicing regulator 3
chr6_-_28943056 0.31 ENSDART00000065138
TBC1 domain family, member 23
chr23_-_19434199 0.31 ENSDART00000132543
kelch domain containing 8B
chr4_-_23082985 0.31 ENSDART00000133644
membrane associated guanylate kinase, WW and PDZ domain containing 2a
chr15_-_6863150 0.30 ENSDART00000153815
myeloid ecotropic viral integration site 3
chr10_+_3049636 0.30 ENSDART00000081794
ENSDART00000183167
ENSDART00000191634
ENSDART00000183514
Ras protein-specific guanine nucleotide-releasing factor 2a
chr21_-_4539899 0.30 ENSDART00000112460
dolichol kinase
chr2_-_18830722 0.30 ENSDART00000165330
ENSDART00000165698
pre-B-cell leukemia homeobox 1a
chrM_+_3803 0.28 ENSDART00000093596
NADH dehydrogenase 1, mitochondrial
chr4_-_6567355 0.27 ENSDART00000134820
ENSDART00000142087
forkhead box P2
chr9_-_10145795 0.27 ENSDART00000004745
ENSDART00000143295
histamine N-methyltransferase
chr9_-_38399432 0.27 ENSDART00000148268
zinc finger protein 142
chr14_+_45883687 0.27 ENSDART00000114790
fibronectin leucine rich transmembrane protein 1b
chr13_-_9875538 0.26 ENSDART00000041609
transmembrane 9 superfamily member 3
chr5_-_31857345 0.25 ENSDART00000112546
protein kinase N3
chr13_+_39182099 0.25 ENSDART00000131434
family with sequence similarity 135, member A
chr16_-_6205790 0.25 ENSDART00000038495
catenin (cadherin-associated protein), beta 1
chr6_-_14038804 0.25 ENSDART00000184606
ENSDART00000184609
ets variant 5b
chr1_-_22803147 0.24 ENSDART00000086867
transmembrane anterior posterior transformation 1b
chr15_+_5132439 0.24 ENSDART00000010350
phosphoglucomutase 2-like 1
chr17_+_49500820 0.23 ENSDART00000170306
apoptosis resistant E3 ubiquitin protein ligase 1
chr6_-_28222592 0.23 ENSDART00000131126
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr23_+_23658474 0.23 ENSDART00000162838
agrin
chr5_-_32489796 0.23 ENSDART00000168870
G protein-coupled receptor 107
chr6_-_13709591 0.22 ENSDART00000151771
chondroitin polymerizing factor b
chr6_+_49551614 0.21 ENSDART00000022581
RAB22A, member RAS oncogene family
chr16_+_38659475 0.21 ENSDART00000023238
ER membrane protein complex subunit 2
chr8_+_26293673 0.21 ENSDART00000144977
monoglyceride lipase
chr17_+_23255365 0.21 ENSDART00000180277

chr11_-_26832685 0.21 ENSDART00000153519
IQ motif and Sec7 domain 1b
chr15_-_20412286 0.21 ENSDART00000008589
calcineurin-like EF-hand protein 2
chr24_+_21540842 0.21 ENSDART00000091529
WAS protein family, member 3b
chr5_+_17624463 0.20 ENSDART00000183869
ENSDART00000081064
fibrosin-like 1
chr14_-_36863432 0.19 ENSDART00000158052
ring finger protein 130
chr3_+_36284986 0.19 ENSDART00000059533
WD repeat domain, phosphoinositide interacting 1
chr10_-_15910974 0.19 ENSDART00000148169
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr25_-_18002498 0.19 ENSDART00000158688
centrosomal protein 290
chr15_-_23942861 0.19 ENSDART00000002824
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr24_-_26715174 0.18 ENSDART00000079726
phospholipase D1b
chr11_-_37717709 0.18 ENSDART00000177280
YOD1 deubiquitinase
chr2_-_22966076 0.18 ENSDART00000143412
ENSDART00000146014
ENSDART00000183443
ENSDART00000191056
ENSDART00000183539
Sin3A-associated protein b
chr7_+_29167744 0.18 ENSDART00000076345
solute carrier family 38, member 8b
chr20_-_23656516 0.17 ENSDART00000149735
carbonyl reductase 4
chr20_-_23657304 0.17 ENSDART00000016913
carbonyl reductase 4
chr15_-_28262632 0.17 ENSDART00000134601
ENSDART00000175022
pre-mRNA processing factor 8
chr10_+_31222433 0.17 ENSDART00000185080
transmembrane protein 218
chr20_+_38837238 0.16 ENSDART00000061334
intraflagellar transport 172
chr4_-_38259998 0.16 ENSDART00000172389
zinc finger protein 1093
chr19_+_26718074 0.16 ENSDART00000134455
zgc:100906
chr2_+_54696042 0.15 ENSDART00000074270
ankyrin repeat domain 12
chr15_+_29116063 0.15 ENSDART00000016112
ENSDART00000153609
ENSDART00000155630
calpain, small subunit 1 b
chr18_-_21685055 0.15 ENSDART00000019861
membrane-bound transcription factor peptidase, site 1
chr6_+_40775800 0.14 ENSDART00000085090
si:ch211-157b11.8
chr24_-_31223232 0.14 ENSDART00000164155
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr13_-_18119696 0.14 ENSDART00000148125
WASH complex subunit 2C
chr2_-_37134169 0.14 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
ELAV like RNA binding protein 1a
chr7_+_30240791 0.13 ENSDART00000109243
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr6_-_54816567 0.13 ENSDART00000150079
troponin I type 1b (skeletal, slow)
chr16_-_31452416 0.13 ENSDART00000140880
ENSDART00000008297
ENSDART00000147373
casein kinase 2, alpha 1 polypeptide
chr19_+_26640096 0.12 ENSDART00000067793
integrator complex subunit 3
chr17_-_32865788 0.12 ENSDART00000077476
prospero homeobox 1a
chr22_+_17286841 0.12 ENSDART00000133176
si:dkey-171o17.8
chr6_+_13207139 0.12 ENSDART00000185601
ENSDART00000182182
INO80 complex subunit Db
chr2_+_30103285 0.12 ENSDART00000019417
DnaJ (Hsp40) homolog, subfamily B, member 6a
chr2_-_55797318 0.12 ENSDART00000158147
calreticulin 3b
chr6_-_34838397 0.11 ENSDART00000060169
ENSDART00000169605
mesoderm induction early response 1a, transcriptional regulator
chr14_-_26425416 0.11 ENSDART00000088690
lectin, mannose-binding 2
chr11_+_6881001 0.11 ENSDART00000170331
kelch-like family member 26
chr11_-_18557929 0.11 ENSDART00000110882
ENSDART00000181381
ENSDART00000189312
death inducer-obliterator 1
chr5_-_69499486 0.10 ENSDART00000023983
ENSDART00000180293
phosphoserine aminotransferase 1
chr1_+_36612660 0.10 ENSDART00000190784
endothelin receptor type Aa
chr16_+_5898878 0.09 ENSDART00000180930
unc-51 like kinase 4
chr3_-_40254634 0.09 ENSDART00000154562
DNA topoisomerase III alpha
chr14_-_32866351 0.09 ENSDART00000166133
ENSDART00000172545
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr13_+_3880882 0.09 ENSDART00000169595
translocase of inner mitochondrial membrane 23 homolog b (yeast)
chr2_+_23039041 0.09 ENSDART00000056921
casein kinase 1, gamma 2a
chr4_-_30712588 0.08 ENSDART00000142393
si:dkey-16p19.5
chr5_-_54395488 0.08 ENSDART00000160781
zinc finger, MYND-type containing 19
chr22_+_30137374 0.08 ENSDART00000187808
adducin 3 (gamma) a
chr9_+_44034790 0.08 ENSDART00000166110
ENSDART00000176954
integrin alpha 4
chr12_-_17199381 0.08 ENSDART00000193292
lipase, gastric
chr2_+_8261109 0.07 ENSDART00000024677
deleted in autism 1a
chr6_+_27992886 0.07 ENSDART00000160354
angiomotin like 2a
chr4_-_28958601 0.07 ENSDART00000111294
zgc:174315
chr2_+_31330358 0.07 ENSDART00000178066
clusterin-like 1 (retinal)
chr2_+_55199721 0.06 ENSDART00000016143
zmp:0000000521
chr4_-_13995766 0.06 ENSDART00000147955
prickle homolog 1b
chr13_-_36050303 0.06 ENSDART00000134955
ENSDART00000139087
legumain
chr4_-_73520581 0.06 ENSDART00000171513
si:ch73-266f23.1
chr12_+_46696867 0.06 ENSDART00000152928
ENSDART00000153445
ENSDART00000123357
ENSDART00000152880
ENSDART00000123834
ENSDART00000174765
ENSDART00000189923
exocyst complex component 7
chr6_-_9236309 0.06 ENSDART00000160397
ENSDART00000164603
IQ motif containing B1
chr2_-_50966124 0.06 ENSDART00000170470
growth hormone releasing hormone receptor a
chr8_+_52442785 0.05 ENSDART00000189958
zgc:77112
chr6_+_3730843 0.05 ENSDART00000019630

chr13_-_3351708 0.05 ENSDART00000042875
si:ch73-193i2.2
chr10_+_26612321 0.04 ENSDART00000134322
four and a half LIM domains 1b
chr7_-_30624435 0.04 ENSDART00000173828
ring finger protein 111
chr3_-_18737126 0.04 ENSDART00000055767
E4F transcription factor 1
chr5_+_32490238 0.04 ENSDART00000191839
NADPH dependent diflavin oxidoreductase 1
chr12_-_11560794 0.03 ENSDART00000149098
ENSDART00000169975
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b
chr3_-_48612078 0.03 ENSDART00000169923
nudE neurodevelopment protein 1-like 1b
chr16_-_47426482 0.03 ENSDART00000148631
ENSDART00000149723
septin 7b
chr13_+_8892784 0.03 ENSDART00000075054
ENSDART00000143705
thyroid adenoma associated
chr18_+_18000887 0.02 ENSDART00000147797
si:ch211-212o1.2
chr8_-_65189 0.02 ENSDART00000168412
hydroxysteroid (17-beta) dehydrogenase 4
chr4_-_18434924 0.02 ENSDART00000190271
suppressor of cytokine signaling 2
chr14_+_2487672 0.02 ENSDART00000170629
ENSDART00000123063
fibroblast growth factor 18a
chr20_-_19530751 0.02 ENSDART00000148574
eukaryotic translation initiation factor 2B, subunit 4 delta
chr12_-_10038870 0.01 ENSDART00000152250
nerve growth factor receptor b
chr19_+_30884960 0.01 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
tyrosyl-tRNA synthetase
chr15_-_2754056 0.01 ENSDART00000129380
protein phosphatase 5, catalytic subunit
chr21_+_4540127 0.01 ENSDART00000043431
nucleoporin 188
chr13_-_25196758 0.01 ENSDART00000184722
adenosine kinase a
chr20_+_34671386 0.01 ENSDART00000152836
ENSDART00000138226
elongator acetyltransferase complex subunit 3
chr22_+_2403068 0.01 ENSDART00000132925
ENSDART00000132569
zgc:112977
chr5_-_24542726 0.01 ENSDART00000182975
tRNA methyltransferase 2 homolog A
chr25_-_37121335 0.01 ENSDART00000017805
nuclear factor of activated T cells 5a
chr19_+_5315987 0.01 ENSDART00000145749
si:dkeyp-113d7.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc12a+hoxc12b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.7 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.7 GO:0014896 muscle hypertrophy(GO:0014896)
0.1 0.4 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.3 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.1 1.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.2 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.7 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 0.3 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.1 0.6 GO:0030431 sleep(GO:0030431)
0.1 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.5 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.5 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.5 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.9 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.5 GO:0021654 rhombomere boundary formation(GO:0021654)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.3 GO:0030878 thyroid gland development(GO:0030878)
0.0 1.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 2.3 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.1 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0005883 neurofilament(GO:0005883)
0.1 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.9 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0030141 secretory granule(GO:0030141)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.5 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 0.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.1 1.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.2 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.8 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.0 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)