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PRJNA207719: Tissue specific transcriptome profiling

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Results for klf7a+klf7b

Z-value: 0.41

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Transcription factors associated with klf7a+klf7b

Gene Symbol Gene ID Gene Info
klf7b
ENSDARG00000043821 Kruppel-like factor 7b
klf7a
ENSDARG00000073857 Kruppel-like factor 7a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf7adr11_v1_chr1_-_6494384_64943840.326.0e-01Click!
klf7bdr11_v1_chr9_-_28399071_283990710.128.5e-01Click!

Activity profile of klf7a+klf7b motif

Sorted Z-values of klf7a+klf7b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_39739627 0.13 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
si:ch211-170d8.5
chr23_-_12015139 0.13 ENSDART00000110627
ENSDART00000193988
ENSDART00000184528
si:dkey-178k16.1
si:dkey-178k16.1
chr23_-_12014931 0.12 ENSDART00000134652
si:dkey-178k16.1
si:dkey-178k16.1
chr2_-_14390627 0.11 ENSDART00000172367
sgip1b
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr19_+_43669122 0.10 ENSDART00000139151
si:ch211-193k19.1
si:ch211-193k19.1
chr16_+_33163858 0.10 ENSDART00000101943
rragca
Ras-related GTP binding Ca
chr12_-_20350629 0.09 ENSDART00000066384
hbbe2
hemoglobin beta embryonic-2
chr8_-_45759137 0.09 ENSDART00000123878
ppiaa
peptidylprolyl isomerase Aa (cyclophilin A)
chr10_+_42462577 0.09 ENSDART00000133463
npy8ar
neuropeptide Y receptor Y8a
chr2_+_54844755 0.08 ENSDART00000170428
rnf126
ring finger protein 126
chr15_-_12229874 0.08 ENSDART00000165159
dscaml1
Down syndrome cell adhesion molecule like 1
chr17_+_12138715 0.08 ENSDART00000112888
SCCPDH (1 of many)
zgc:174379
chr8_+_23034718 0.07 ENSDART00000184512
ythdf1
YTH N(6)-methyladenosine RNA binding protein 1
chr10_-_41157135 0.07 ENSDART00000134851
aak1b
AP2 associated kinase 1b
chr17_-_49339677 0.07 ENSDART00000047857
orc3
origin recognition complex, subunit 3
chr16_+_53519048 0.07 ENSDART00000124691
smpd5
sphingomyelin phosphodiesterase 5
chr19_+_19511394 0.06 ENSDART00000172410
jazf1a
JAZF zinc finger 1a
chr15_+_17441734 0.06 ENSDART00000153729
snx19b
sorting nexin 19b
chr11_-_16115804 0.06 ENSDART00000143436
ENSDART00000157928
rpf1
ribosome production factor 1 homolog
chr25_+_21098990 0.06 ENSDART00000017488
rad52
RAD52 homolog, DNA repair protein
chr1_+_39990547 0.05 ENSDART00000112150
sod3b
superoxide dismutase 3, extracellular b
chr5_+_32791245 0.05 ENSDART00000077189
ier5l
immediate early response 5-like
chr25_+_21098675 0.05 ENSDART00000079012
rad52
RAD52 homolog, DNA repair protein
chr1_+_16574312 0.05 ENSDART00000187067
mtus1b
microtubule associated tumor suppressor 1b
chr5_+_26795465 0.05 ENSDART00000053001
tcn2
transcobalamin II
chr21_+_8427059 0.05 ENSDART00000143151
dennd1a
DENN/MADD domain containing 1A
chr10_+_76864 0.05 ENSDART00000036375
vps26c
Down syndrome critical region 3
chr6_-_10034145 0.05 ENSDART00000185999
nudt15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr3_-_28872756 0.04 ENSDART00000138840
eef2kmt
eukaryotic elongation factor 2 lysine methyltransferase
chr7_-_30087048 0.04 ENSDART00000112743
nmbb
neuromedin Bb
chr6_+_30668098 0.04 ENSDART00000112294
ttc22
tetratricopeptide repeat domain 22
chr7_+_24081167 0.04 ENSDART00000141749
acin1b
apoptotic chromatin condensation inducer 1b
chr8_+_44475793 0.04 ENSDART00000190118
si:ch73-211l2.3
si:ch73-211l2.3
chr8_+_54013199 0.03 ENSDART00000158497
CABZ01079663.1

chr19_+_23982466 0.03 ENSDART00000080673
syt11a
synaptotagmin XIa
chr15_+_5132439 0.03 ENSDART00000010350
pgm2l1
phosphoglucomutase 2-like 1
chr8_+_53423408 0.03 ENSDART00000164792
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr22_+_980290 0.02 ENSDART00000065377
def6b
differentially expressed in FDCP 6b homolog (mouse)
chr24_-_21487609 0.02 ENSDART00000191325
atp8a2
ATPase phospholipid transporting 8A2
chr16_-_31686602 0.02 ENSDART00000170357
c1s
complement component 1, s subcomponent
chr11_-_2594045 0.02 ENSDART00000114079
nab2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr17_-_37795865 0.02 ENSDART00000025853
zfp36l1a
zinc finger protein 36, C3H type-like 1a
chr5_-_26795438 0.01 ENSDART00000146124
si:ch211-102c2.7
si:ch211-102c2.7
chr20_+_20731633 0.01 ENSDART00000191952
ENSDART00000165224
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr25_-_16056292 0.01 ENSDART00000186071
cyb5r2
cytochrome b5 reductase 2
chr13_-_17464362 0.00 ENSDART00000145499
lrmda
leucine rich melanocyte differentiation associated
chr18_+_3243292 0.00 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr25_-_36827491 0.00 ENSDART00000170941
CU929365.1

chr22_+_17784414 0.00 ENSDART00000188189
ENSDART00000145260
tm6sf2
transmembrane 6 superfamily member 2
chr8_-_22288258 0.00 ENSDART00000140978
ENSDART00000100046
si:ch211-147a11.3
si:ch211-147a11.3

Network of associatons between targets according to the STRING database.

First level regulatory network of klf7a+klf7b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions