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PRJNA207719: Tissue specific transcriptome profiling

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Results for lhx8a+lhx8b

Z-value: 0.69

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Transcription factors associated with lhx8a+lhx8b

Gene Symbol Gene ID Gene Info
ENSDARG00000002330 LIM homeobox 8a
ENSDARG00000042145 LIM homeobox 8b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx8bdr11_v1_chr8_-_17926814_179268140.167.9e-01Click!
lhx8adr11_v1_chr2_+_11206317_11206317-0.069.2e-01Click!

Activity profile of lhx8a+lhx8b motif

Sorted Z-values of lhx8a+lhx8b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_7546259 0.53 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr5_+_32247310 0.47 ENSDART00000182649
myosin, heavy chain a
chr10_-_43568239 0.44 ENSDART00000131731
ENSDART00000097433
ENSDART00000131309
myocyte enhancer factor 2ca
chr15_-_23645810 0.40 ENSDART00000168845
creatine kinase, muscle b
chr8_-_53198154 0.38 ENSDART00000083416
gamma-aminobutyric acid (GABA) A receptor, delta
chr17_-_6730247 0.37 ENSDART00000031091
visinin-like 1b
chr19_-_31042570 0.36 ENSDART00000144337
ENSDART00000136213
ENSDART00000133101
ENSDART00000190949
basic leucine zipper and W2 domains 2
chr8_+_3820134 0.36 ENSDART00000122454
citron rho-interacting serine/threonine kinase b
chr24_+_792429 0.35 ENSDART00000082523
inositol(myo)-1(or 4)-monophosphatase 2
chr14_+_17197132 0.33 ENSDART00000054598
reticulon 4 receptor-like 2b
chr12_-_4756478 0.33 ENSDART00000152181
microtubule-associated protein tau a
chr18_+_924949 0.31 ENSDART00000170888
ENSDART00000193163
pyruvate kinase M1/2a
chr9_-_41277347 0.31 ENSDART00000181213
glutaminase b
chr3_-_15264698 0.30 ENSDART00000111948
ENSDART00000142594
seizure related 6 homolog (mouse)-like 2
chr16_+_45739193 0.29 ENSDART00000184852
ENSDART00000156851
ENSDART00000154704
progestin and adipoQ receptor family member VI
chr21_+_13861589 0.28 ENSDART00000015629
ENSDART00000171306
syntaxin binding protein 1a
chr7_+_41887429 0.27 ENSDART00000115090
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr24_+_38306010 0.27 ENSDART00000143184
myosin binding protein C, fast type b
chr6_+_40661703 0.26 ENSDART00000142492
enolase 1b, (alpha)
chr23_-_29668286 0.24 ENSDART00000129248
calsyntenin 1
chr4_+_11479705 0.23 ENSDART00000019458
ENSDART00000150587
ENSDART00000139370
ENSDART00000135826
ankyrin repeat and SOCS box containing 13a, tandem duplicate 1
chr6_-_32093830 0.23 ENSDART00000017695
forkhead box D3
chr10_+_21804772 0.23 ENSDART00000162194
protocadherin 1 gamma 31
chr20_-_39273987 0.22 ENSDART00000127173
clusterin
chr2_-_34555945 0.22 ENSDART00000056671
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr4_-_17785120 0.22 ENSDART00000024775
myosin binding protein C, slow type
chr15_+_25683069 0.21 ENSDART00000148190
hypermethylated in cancer 1
chr5_+_27137473 0.21 ENSDART00000181833
unc-5 netrin receptor Db
chr6_+_12865137 0.21 ENSDART00000090065
family with sequence similarity 117, member Ba
chr16_-_25535430 0.20 ENSDART00000077420
dystrobrevin binding protein 1a
chr14_+_19258702 0.20 ENSDART00000187087
ENSDART00000005738
SLIT and NTRK-like family, member 2
chr22_-_15562933 0.20 ENSDART00000141528
ankyrin repeat and MYND domain containing 1
chr17_+_33496067 0.20 ENSDART00000184724
parathyroid hormone 2
chr9_+_6079528 0.20 ENSDART00000142167
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr21_-_26918901 0.20 ENSDART00000100685
leucine rich repeat and fibronectin type III domain containing 4a
chr2_-_14387335 0.19 ENSDART00000189332
ENSDART00000164786
ENSDART00000188572
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr10_-_7974155 0.19 ENSDART00000147368
ENSDART00000075524
oxysterol binding protein 2
chr15_+_11427620 0.19 ENSDART00000168688
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr18_-_898870 0.19 ENSDART00000151777
ENSDART00000062654
poly (ADP-ribose) polymerase family, member 6a
chr11_-_43200994 0.19 ENSDART00000164700
spectrin, beta, non-erythrocytic 1
chr18_+_17583479 0.18 ENSDART00000186977
ENSDART00000010998
solute carrier family 12 (sodium/chloride transporter), member 3
chr2_+_20332044 0.18 ENSDART00000112131
phospholipid phosphatase related 4a
chr6_+_11249706 0.18 ENSDART00000186547
ENSDART00000193287
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr9_-_18568927 0.18 ENSDART00000084668
ecto-NOX disulfide-thiol exchanger 1
chr20_-_39273505 0.18 ENSDART00000153114
clusterin
chr5_+_57320113 0.18 ENSDART00000036331
ATPase H+ transporting V1 subunit G1
chr3_-_28428198 0.17 ENSDART00000151546
RNA binding fox-1 homolog 1
chr16_-_35329803 0.17 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
protein tyrosine phosphatase, receptor type, U, b
chr18_+_31410652 0.17 ENSDART00000098504
differentially expressed in FDCP 8 homolog (mouse)
chr21_-_25601648 0.17 ENSDART00000042578
EGF containing fibulin extracellular matrix protein 2b
chr2_-_34483597 0.16 ENSDART00000133224
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr21_-_36972127 0.16 ENSDART00000100310
drebrin 1
chr11_+_30981777 0.16 ENSDART00000148949
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr3_+_16724614 0.16 ENSDART00000182135
glycogen synthase 1 (muscle)
chr9_-_21918963 0.15 ENSDART00000090782
LIM domain 7a
chr5_-_22882210 0.15 ENSDART00000182232
si:ch211-26b3.4
chr3_-_32169754 0.15 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr4_-_23963838 0.15 ENSDART00000133433
ENSDART00000132615
ENSDART00000135942
ENSDART00000139439
cugbp, Elav-like family member 2
chr23_+_23182037 0.15 ENSDART00000137353
kelch-like family member 17
chr1_+_10019653 0.14 ENSDART00000190227
tripartite motif containing 2b
chr7_+_26224211 0.14 ENSDART00000173999
VGF nerve growth factor inducible
chr24_+_39137001 0.14 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
TBC1 domain family, member 24
chr2_+_20331445 0.14 ENSDART00000186880
phospholipid phosphatase related 4a
chr6_+_11250033 0.14 ENSDART00000065411
ENSDART00000132677
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr9_+_49712868 0.14 ENSDART00000192969
ENSDART00000183310
cysteine and serine rich nuclear protein 3
chr2_-_32384683 0.14 ENSDART00000182942
ENSDART00000141757
upstream binding transcription factor, like
chr20_+_18551657 0.14 ENSDART00000147001
si:dkeyp-72h1.1
chr8_+_7737062 0.13 ENSDART00000166712
FYVE, RhoGEF and PH domain containing 1
chr2_-_48826707 0.13 ENSDART00000134711
supervillin b
chr18_-_2707218 0.13 ENSDART00000175226
si:ch211-248g20.5
chr20_+_16170848 0.13 ENSDART00000182115
zyg-11 homolog (C. elegans)
chr8_+_31008287 0.13 ENSDART00000129882
ENSDART00000180694
prostaglandin E synthase 2-like
chr4_+_14727018 0.12 ENSDART00000124189
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr15_-_45246911 0.12 ENSDART00000189557
ENSDART00000185291

chr23_-_21797517 0.12 ENSDART00000110041
leucine rich repeat containing 38a
chr9_+_25775816 0.12 ENSDART00000127834
ENSDART00000189994
zinc finger E-box binding homeobox 2a
chr12_+_42574148 0.12 ENSDART00000157855
early B cell factor 3a
chr9_+_25776971 0.11 ENSDART00000146011
zinc finger E-box binding homeobox 2a
chr5_-_46505691 0.11 ENSDART00000111589
ENSDART00000122966
ENSDART00000166907
hyaluronan and proteoglycan link protein 1a
chr10_+_21656654 0.11 ENSDART00000160464
protocadherin 1 gamma 2
chr7_-_31441420 0.11 ENSDART00000075398
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr20_+_23173710 0.11 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr1_+_14073891 0.11 ENSDART00000021693
ankyrin 2a, neuronal
chr2_-_32551178 0.11 ENSDART00000145603
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr7_+_72469724 0.11 ENSDART00000187629
HECT domain E3 ubiquitin protein ligase 4
chr17_-_2386569 0.11 ENSDART00000121614
phospholipase C beta 2
chr14_-_33105434 0.11 ENSDART00000163795
discs, large homolog 3 (Drosophila)
chr10_+_42733210 0.10 ENSDART00000189832

chr14_-_25577094 0.10 ENSDART00000163669
complexin 2
chr1_-_21538673 0.10 ENSDART00000131257
WD repeat domain 19
chr18_+_7286788 0.10 ENSDART00000022998
si:ch73-86n2.1
chr8_+_6967108 0.10 ENSDART00000004588
acid-sensing (proton-gated) ion channel 1a
chr1_+_52929185 0.10 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr1_-_40086978 0.10 ENSDART00000136990
si:dkey-117m1.4
chr12_+_9551667 0.10 ENSDART00000048493
ENSDART00000166178
prolyl 4-hydroxylase, alpha polypeptide I a
chr20_-_22198982 0.10 ENSDART00000063578
steroid 5 alpha-reductase 3
chr4_+_14727212 0.10 ENSDART00000158094
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr9_+_42607138 0.09 ENSDART00000138133
ENSDART00000002027
GULP, engulfment adaptor PTB domain containing 1a
chr23_+_34321237 0.09 ENSDART00000173272
plexin A1a
chr18_+_26899316 0.09 ENSDART00000050230
tetraspanin 3a
chr17_-_8173380 0.09 ENSDART00000148520
spectrin repeat containing, nuclear envelope 1b
chr3_+_15773991 0.09 ENSDART00000089923
zinc finger protein 652
chr5_-_8614217 0.09 ENSDART00000164844
RPTOR independent companion of MTOR, complex 2 a
chr22_-_7129631 0.09 ENSDART00000171359
acid-sensing (proton-gated) ion channel 1b
chr16_-_35427060 0.09 ENSDART00000172294
CTP synthase 1b
chr19_+_46222428 0.09 ENSDART00000183984
vacuolar protein sorting 28 (yeast)
chr1_-_55873178 0.08 ENSDART00000019936
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
chr6_-_957830 0.08 ENSDART00000090019
ENSDART00000184286
zinc finger E-box binding homeobox 2b
chr11_+_36355348 0.08 ENSDART00000145427
synaptophysin-like 2a
chr14_-_23801389 0.08 ENSDART00000054264
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_+_11250316 0.08 ENSDART00000137122
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr24_+_39027481 0.08 ENSDART00000085565
calpain 15
chr12_+_18782821 0.08 ENSDART00000152918
megakaryoblastic leukemia (translocation) 1b
chr9_-_16877456 0.07 ENSDART00000161105
ENSDART00000160869
F-box and leucine-rich repeat protein 3a
chr4_+_15605844 0.07 ENSDART00000101619
ENSDART00000021384
exocyst complex component 4
chr9_+_42606681 0.07 ENSDART00000191186
GULP, engulfment adaptor PTB domain containing 1a
chr5_+_51909740 0.07 ENSDART00000162541
thrombospondin 4a
chr12_+_4869248 0.07 ENSDART00000170961
sodium channel, voltage-gated, type IV, alpha, a
chr8_-_23612462 0.07 ENSDART00000025024
solute carrier family 38, member 5b
chr3_-_17716322 0.07 ENSDART00000192664

chr18_+_9635178 0.07 ENSDART00000183486
piccolo presynaptic cytomatrix protein b
chr7_-_32629458 0.07 ENSDART00000001376
ADP-ribosylation factor-like 14 effector protein
chr8_+_10823069 0.07 ENSDART00000081341
mitogen-activated protein kinase 13
chr25_+_28893615 0.07 ENSDART00000156994
ENSDART00000075151
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr7_-_22941472 0.07 ENSDART00000190334
TNF superfamily member 10, like
chr12_-_24812403 0.07 ENSDART00000185517
forkhead box N2b
chr7_-_51727760 0.07 ENSDART00000174180
histone deacetylase 8
chr7_-_30280934 0.07 ENSDART00000126741
small EDRK-rich factor 2
chr21_+_27302752 0.07 ENSDART00000012855
SART1, U4/U6.U5 tri-snRNP-associated protein 1
chr5_+_36654817 0.07 ENSDART00000131339
calpain, small subunit 1 a
chr2_-_3403020 0.07 ENSDART00000092741
synaptosomal-associated protein, 47
chr21_+_21201346 0.07 ENSDART00000142961
RPTOR independent companion of MTOR, complex 2b
chr13_-_33667922 0.06 ENSDART00000141631
si:dkey-76k16.5
chr25_-_348784 0.06 ENSDART00000059514
prickle homolog 1a
chr18_+_30028637 0.06 ENSDART00000139750
si:ch211-220f16.1
chr15_-_25613114 0.06 ENSDART00000182431
ENSDART00000187405
TAO kinase 1a
chr18_-_158541 0.06 ENSDART00000188914
ENSDART00000191052
transient receptor potential cation channel, subfamily M, member 7
chr1_-_7673376 0.06 ENSDART00000013264
arginine and glutamate rich 1b
chr7_+_26326462 0.06 ENSDART00000173515
zonadhesin, like
chr21_-_10488379 0.06 ENSDART00000163878
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr19_+_19511394 0.06 ENSDART00000172410
JAZF zinc finger 1a
chr16_+_49088698 0.06 ENSDART00000182037
phospholipase C like 2
chr11_-_4175773 0.06 ENSDART00000042221
coiled-coil domain containing 3b
chr20_-_25436389 0.06 ENSDART00000153266
intersectin 2a
chr3_-_34180364 0.06 ENSDART00000151819
ENSDART00000003133
Yip1 domain family, member 2
chr17_-_33412868 0.06 ENSDART00000187521

chr13_+_23162447 0.06 ENSDART00000180209
sorbin and SH3 domain containing 1
chr19_-_40191358 0.06 ENSDART00000183919
granulin 1
chr19_-_6303099 0.06 ENSDART00000133371
POU class 2 homeobox 2a
chr22_+_38164486 0.06 ENSDART00000137521
transmembrane 4 L six family member 18
chr7_+_27253063 0.06 ENSDART00000191138
SRY (sex determining region Y)-box 6
chr8_-_2289264 0.06 ENSDART00000189397
plasminogen activator, tissue
chr3_-_45281350 0.05 ENSDART00000020168
potassium channel tetramerization domain containing 5a
chr15_+_36966369 0.05 ENSDART00000163622
kirre like nephrin family adhesion molecule 3, like
chr2_+_50062165 0.05 ENSDART00000097939
ENSDART00000138214
zinc finger, CCHC domain containing 2
chr9_-_7640692 0.05 ENSDART00000135616
DnaJ (Hsp40) homolog, subfamily B, member 2
chr24_-_21819010 0.05 ENSDART00000091096

chr22_-_29586608 0.05 ENSDART00000059869
adrenoceptor alpha 2A
chr19_-_43004356 0.05 ENSDART00000098101
zinc finger, CCHC domain containing 17
chr20_-_47953524 0.05 ENSDART00000167986
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr3_+_25166805 0.05 ENSDART00000077493
zgc:162544
chr7_-_18416741 0.05 ENSDART00000097882
somatostatin receptor 1b
chr11_+_24620742 0.05 ENSDART00000182471
ENSDART00000048365
synaptotagmin VIb
chr13_+_10970614 0.05 ENSDART00000058147
dynein, cytoplasmic 2, light intermediate chain 1
chr13_+_29771463 0.05 ENSDART00000134424
ENSDART00000138332
ENSDART00000134330
ENSDART00000160944
ENSDART00000076992
ENSDART00000160921
paired box 2a
chr9_+_13230214 0.05 ENSDART00000017932
ENSDART00000179850
calcium responsive transcription factor
chr24_+_19578935 0.05 ENSDART00000137175
sulfatase 1
chr3_-_32603191 0.05 ENSDART00000150997
si:ch73-248e21.7
chr20_-_51727860 0.05 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr5_+_51026563 0.04 ENSDART00000050988
glucosaminyl (N-acetyl) transferase 4, core 2, a
chr4_+_9536860 0.04 ENSDART00000130083
LSM8 homolog, U6 small nuclear RNA associated
chr25_-_28768489 0.04 ENSDART00000088315
WASH complex subunit 4
chr6_-_57938043 0.04 ENSDART00000171073
TOX high mobility group box family member 2
chr2_+_30513887 0.04 ENSDART00000137048
membrane-associated ring finger (C3HC4) 6
chr18_-_21105968 0.04 ENSDART00000100791
si:dkey-12e7.1
chr10_-_42131408 0.04 ENSDART00000076693
STAM binding protein a
chr9_-_4606463 0.04 ENSDART00000179110
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr24_-_32025637 0.04 ENSDART00000180448
ENSDART00000159034
Ras suppressor protein 1
chr5_+_33339762 0.04 ENSDART00000026085
prostaglandin E synthase
chr20_+_28434196 0.04 ENSDART00000034245
D4, zinc and double PHD fingers, family 3
chr16_-_30869732 0.04 ENSDART00000042716
ENSDART00000190168
protein tyrosine kinase 2ab
chr19_+_4139065 0.04 ENSDART00000172524
si:dkey-218f9.10
chr21_-_17016788 0.04 ENSDART00000186703

chr16_-_36979592 0.04 ENSDART00000168443
small nuclear ribonucleoprotein 48 (U11/U12)
chr1_-_23268569 0.04 ENSDART00000143948
replication factor C (activator 1) 1
chr11_-_14789918 0.04 ENSDART00000179670
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr18_-_46957840 0.04 ENSDART00000182754
GRAM domain containing 1Bb
chr23_-_43393589 0.04 ENSDART00000183592
zgc:174862
chr11_+_44236183 0.04 ENSDART00000193470
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr10_+_20364009 0.03 ENSDART00000186139
ENSDART00000080395
golgin A7
chr1_+_30100257 0.03 ENSDART00000134311
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_+_55095314 0.03 ENSDART00000132727
aftiphilin a
chr9_-_16853462 0.03 ENSDART00000160273

chr8_+_26254903 0.03 ENSDART00000113763
solute carrier family 26, member 6
chr20_-_10120442 0.03 ENSDART00000144970
Meis homeobox 2b
chr15_-_24960730 0.03 ENSDART00000109990
ENSDART00000186706
abhydrolase domain containing 15a
chr7_-_64770456 0.03 ENSDART00000192618
zinc finger, DHHC-type containing 21
chr18_-_26811959 0.03 ENSDART00000086250
zinc finger protein 592
chr6_+_2195625 0.03 ENSDART00000155659
activin A receptor type 1Bb
chr4_-_42171503 0.03 ENSDART00000163798
zinc finger protein 1148

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx8a+lhx8b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0036076 ligamentous ossification(GO:0036076)
0.1 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.2 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0097066 response to thyroid hormone(GO:0097066)
0.0 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.3 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.2 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.0 0.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.4 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0071387 cellular response to cortisol stimulus(GO:0071387) response to dexamethasone(GO:0071548)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.2 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.0 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.1 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.2 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.1 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0097268 cytoophidium(GO:0097268)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.0 GO:0072380 TRC complex(GO:0072380)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions