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PRJNA207719: Tissue specific transcriptome profiling

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Results for mafaa

Z-value: 0.74

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Transcription factors associated with mafaa

Gene Symbol Gene ID Gene Info
mafaa
ENSDARG00000044155 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafaadr11_v1_chr6_-_32703317_32703317-0.731.6e-01Click!

Activity profile of mafaa motif

Sorted Z-values of mafaa motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_39313027 1.24 ENSDART00000012644
krt4
keratin 4
chr13_+_4671698 1.08 ENSDART00000164617
ENSDART00000128494
ENSDART00000165776
pla2g12b
phospholipase A2, group XIIB
chr4_-_8030583 1.08 ENSDART00000113628
si:ch211-240l19.8
si:ch211-240l19.8
chr10_+_19596214 0.89 ENSDART00000183110
CABZ01059626.1

chr2_-_22688651 0.82 ENSDART00000013863
agxtb
alanine-glyoxylate aminotransferase b
chr19_-_5332784 0.72 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr7_+_27603211 0.69 ENSDART00000148782
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr8_-_50482781 0.64 ENSDART00000056361
ido1
indoleamine 2,3-dioxygenase 1
chr24_+_6353394 0.58 ENSDART00000165118
CR352329.1

chr1_+_59090743 0.50 ENSDART00000100199
mfap4
microfibril associated protein 4
chr1_+_59090972 0.49 ENSDART00000171497
mfap4
microfibril associated protein 4
chr20_-_23440955 0.46 ENSDART00000153386
slc10a4
solute carrier family 10, member 4
chr3_-_1388936 0.42 ENSDART00000171278
ddx47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr1_+_59090583 0.41 ENSDART00000150658
mfap4
microfibril associated protein 4
chr19_-_48010490 0.39 ENSDART00000159938
FBXL19
zgc:158376
chr4_-_58448785 0.38 ENSDART00000172359
si:ch211-212k5.3
si:ch211-212k5.3
chr6_-_33913184 0.37 ENSDART00000146373
nasp
nuclear autoantigenic sperm protein (histone-binding)
chr4_-_8040436 0.36 ENSDART00000113033
si:ch211-240l19.6
si:ch211-240l19.6
chr3_-_10677890 0.35 ENSDART00000155382
ENSDART00000171319
si:ch1073-144j5.2
si:ch1073-144j5.2
chr24_-_6029314 0.34 ENSDART00000136155
ftr60
finTRIM family, member 60
chr21_-_1642739 0.31 ENSDART00000151118
zgc:152948
zgc:152948
chr5_-_33230794 0.30 ENSDART00000144273
kank1b
KN motif and ankyrin repeat domains 1b
chr16_-_46567344 0.30 ENSDART00000127721
si:dkey-152b24.7
si:dkey-152b24.7
chr4_-_72468168 0.29 ENSDART00000182995
ENSDART00000174067
CR788316.1

chr7_+_6969909 0.28 ENSDART00000189886
actn3b
actinin alpha 3b
chr13_-_28272299 0.28 ENSDART00000006393
tlx1
T cell leukemia homeobox 1
chr25_+_31264155 0.28 ENSDART00000012256
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr24_+_37709191 0.27 ENSDART00000066558
decr2
2,4-dienoyl CoA reductase 2, peroxisomal
chr1_+_52392511 0.27 ENSDART00000144025
si:ch211-217k17.8
si:ch211-217k17.8
chr3_-_34055745 0.27 ENSDART00000151652
ighv2-2
immunoglobulin heavy variable 2-2
chr8_+_52479026 0.26 ENSDART00000162885
FO704661.1
Danio rerio gamma-glutamyl hydrolase (LOC553228), mRNA.
chr11_+_25276748 0.26 ENSDART00000126211
cyldb
cylindromatosis (turban tumor syndrome), b
chr19_-_3777217 0.25 ENSDART00000160510
si:dkey-206d17.15
si:dkey-206d17.15
chr5_-_23795688 0.25 ENSDART00000099084
gbgt1l4
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr25_+_3217419 0.23 ENSDART00000104859
rccd1
RCC1 domain containing 1
chr25_-_27842654 0.23 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr6_+_42475730 0.23 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr13_-_50463938 0.22 ENSDART00000083857
ccnj
cyclin J
chr21_+_18885258 0.22 ENSDART00000169078
si:dkey-65l23.2
si:dkey-65l23.2
chr4_+_56422336 0.22 ENSDART00000159185
si:dkey-65l23.2
si:dkey-65l23.2
chr8_+_43078044 0.22 ENSDART00000147872
si:dkey-65l23.2
si:dkey-65l23.2
chr23_+_3538463 0.20 ENSDART00000172758
si:dkey-9l20.3
si:dkey-9l20.3
chr16_+_4658250 0.19 ENSDART00000006212
LIN28A
si:ch1073-284b18.2
chr3_+_26322596 0.19 ENSDART00000172700
si:ch211-156b7.5
si:ch211-156b7.5
chr16_+_42465518 0.19 ENSDART00000058699
si:ch211-215k15.4
si:ch211-215k15.4
chr3_-_62417677 0.18 ENSDART00000101888
sstr2b
somatostatin receptor 2b
chr23_+_12916062 0.18 ENSDART00000144268
si:dkey-150i13.2
si:dkey-150i13.2
chr14_+_40641350 0.18 ENSDART00000074506
tnmd
tenomodulin
chr25_+_459901 0.17 ENSDART00000154895
prtgb
protogenin homolog b (Gallus gallus)
chr18_+_33591704 0.17 ENSDART00000185631
ENSDART00000057845
si:dkey-47k20.5
si:dkey-47k20.5
chr22_+_28328156 0.17 ENSDART00000166714
impg2b
interphotoreceptor matrix proteoglycan 2b
chr13_-_301309 0.16 ENSDART00000131747
chs1
chitin synthase 1
chr21_+_45841731 0.16 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr2_-_37465517 0.16 ENSDART00000139983
si:dkey-57k2.6
si:dkey-57k2.6
chr21_-_17037907 0.15 ENSDART00000101263
ube2g1b
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr23_+_42338325 0.15 ENSDART00000169660
cyp2aa7
cytochrome P450, family 2, subfamily AA, polypeptide 7
chr12_-_11649690 0.15 ENSDART00000149713
btbd16
BTB (POZ) domain containing 16
chr22_+_10606863 0.15 ENSDART00000147975
rad54l2
RAD54 like 2
chr3_+_8826905 0.15 ENSDART00000167474
ENSDART00000168088
si:dkeyp-30d6.2
si:dkeyp-30d6.2
chr8_-_3336273 0.14 ENSDART00000081160
zgc:173737
zgc:173737
chr4_-_50926767 0.14 ENSDART00000183430
si:ch211-208f21.3
si:ch211-208f21.3
chr11_+_6115621 0.13 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr8_-_2591654 0.13 ENSDART00000049109
seta
SET nuclear proto-oncogene a
chr9_-_1639884 0.13 ENSDART00000062850
ENSDART00000150947
agps
alkylglycerone phosphate synthase
chr13_+_6295173 0.13 ENSDART00000163855
angpt2a
angiopoietin 2a
chr23_+_42652877 0.12 ENSDART00000035654
cyp2ae1
cytochrome P450, family 2, subfamily AE, polypeptide 1
chr25_-_3217115 0.12 ENSDART00000032390
gtf2h1
general transcription factor IIH, polypeptide 1
chr12_+_30789611 0.11 ENSDART00000181501
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr17_-_42798332 0.11 ENSDART00000189885
prkd3
protein kinase D3
chr7_-_7493758 0.11 ENSDART00000036703
pfdn2
prefoldin subunit 2
chr6_-_25371196 0.11 ENSDART00000187291
PKN2 (1 of many)
zgc:153916
chr2_+_38161318 0.10 ENSDART00000044264
mmp14b
matrix metallopeptidase 14b (membrane-inserted)
chr1_-_26045007 0.10 ENSDART00000129259
gpank1
G patch domain and ankyrin repeats 1
chr8_+_50534948 0.10 ENSDART00000174435
PEBP4
phosphatidylethanolamine binding protein 4
chr22_+_19283978 0.10 ENSDART00000131487
ENSDART00000143589
si:dkey-21e2.14
si:dkey-21e2.14
chr10_-_57270 0.08 ENSDART00000058411
hlcs
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr4_-_14486822 0.07 ENSDART00000048821
plxnb2a
plexin b2a
chr20_-_22476255 0.07 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr2_-_37896965 0.06 ENSDART00000129852
hbl1
hexose-binding lectin 1
chr8_-_21071476 0.06 ENSDART00000184184
ENSDART00000100288
zgc:112962
zgc:112962
chr22_+_12477996 0.06 ENSDART00000177704
CR847870.3

chr15_-_17138640 0.06 ENSDART00000080777
mrpl28
mitochondrial ribosomal protein L28
chr22_-_27709692 0.05 ENSDART00000172458
CR547131.1

chr8_-_21071711 0.05 ENSDART00000111600
ENSDART00000135204
ENSDART00000131371
ENSDART00000146532
ENSDART00000137606
zgc:112962
zgc:112962
chr1_-_16676177 0.04 ENSDART00000159038
frg1
FSHD region gene 1
chr20_-_23946296 0.04 ENSDART00000143005
mdn1
midasin AAA ATPase 1
chr20_+_54323218 0.02 ENSDART00000191096
CABZ01077555.1

chr17_-_20202725 0.01 ENSDART00000133650
ecd
ecdysoneless homolog (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of mafaa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0006545 glycine biosynthetic process(GO:0006545)
0.1 0.7 GO:0070640 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 0.4 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 1.1 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) arachidonate transport(GO:1903963)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0030428 cell septum(GO:0030428)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.8 GO:0008483 transaminase activity(GO:0008483)
0.0 1.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.2 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)