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PRJNA207719: Tissue specific transcriptome profiling

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Results for myca+mych

Z-value: 0.81

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Transcription factors associated with myca+mych

Gene Symbol Gene ID Gene Info
ENSDARG00000045695 MYC proto-oncogene, bHLH transcription factor a
ENSDARG00000077473 myelocytomatosis oncogene homolog

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycadr11_v1_chr24_+_10414028_10414028-0.847.4e-02Click!
mychdr11_v1_chr6_+_50451337_504513370.612.7e-01Click!

Activity profile of myca+mych motif

Sorted Z-values of myca+mych motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_31555696 0.70 ENSDART00000053539
transcription factor 21
chr18_+_5490668 0.64 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr19_+_42983613 0.59 ENSDART00000033724
fatty acid binding protein 3, muscle and heart
chr6_-_39764995 0.58 ENSDART00000085277
phosphofructokinase, muscle b
chr14_+_22076596 0.51 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr6_-_21189295 0.48 ENSDART00000137136
obscurin-like 1a
chr18_-_11729 0.48 ENSDART00000159781
WAS protein homolog associated with actin, golgi membranes and microtubules
chr22_+_6293563 0.45 ENSDART00000063416
ribonuclease like 2
chr2_-_42375275 0.44 ENSDART00000026339
GTP binding protein 4
chr19_-_24555935 0.43 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr14_+_23518110 0.42 ENSDART00000112930
si:ch211-221f10.2
chr8_+_44783424 0.41 ENSDART00000025875
si:ch1073-459j12.1
chr21_-_20765338 0.41 ENSDART00000135940
growth hormone receptor b
chr7_+_54605640 0.40 ENSDART00000168474
fibroblast growth factor 3
chr9_+_56422517 0.40 ENSDART00000168620
G protein-coupled receptor 39
chr18_+_8917766 0.39 ENSDART00000145226
si:ch211-233h19.2
chr7_-_73752955 0.39 ENSDART00000171254
ENSDART00000009888
calsequestrin 1b
chr12_+_30586599 0.38 ENSDART00000124920
ENSDART00000126984
nebulin-related anchoring protein
chr22_-_5323482 0.37 ENSDART00000145785
sphingosine-1-phosphate receptor 4
chr19_-_34117056 0.37 ENSDART00000158677
si:dkey-184p18.2
chr19_-_24555623 0.37 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr9_+_56422311 0.37 ENSDART00000171958
G protein-coupled receptor 39
chr15_+_6661343 0.36 ENSDART00000160136
NOP53 ribosome biogenesis factor
chr5_-_3927692 0.35 ENSDART00000146840
ENSDART00000058346
complement component 1, q subcomponent binding protein
chr5_-_69314495 0.34 ENSDART00000182335
smoothelin b
chr22_+_5120033 0.34 ENSDART00000169200
muscle-specific beta 1 integrin binding protein
chr19_+_43119698 0.32 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eukaryotic translation elongation factor 1 alpha 1, like 1
chr5_+_3927989 0.32 ENSDART00000030125
zinc finger, HIT-type containing 3
chr12_-_33359052 0.32 ENSDART00000135943
solute carrier family 16 (monocarboxylate transporter), member 3
chr21_+_11969603 0.32 ENSDART00000142247
ENSDART00000140652
motilin-like
chr12_-_33359654 0.32 ENSDART00000001907
solute carrier family 16 (monocarboxylate transporter), member 3
chr13_-_12021566 0.32 ENSDART00000125430
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr11_-_37995501 0.31 ENSDART00000192096
solute carrier family 41 (magnesium transporter), member 1
chr16_-_38629208 0.31 ENSDART00000126705
eukaryotic translation initiation factor 3, subunit E, a
chr22_-_607812 0.31 ENSDART00000145983
cyclin-dependent kinase inhibitor 1A
chr20_+_46660339 0.30 ENSDART00000016530
adenylate cyclase 3b
chr16_-_42186093 0.30 ENSDART00000076030
fibrillarin
chr17_+_8212477 0.30 ENSDART00000064665
solute carrier family 18, subfamily B, member 1
chr9_-_12888082 0.30 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
chr22_+_5118361 0.29 ENSDART00000168371
ENSDART00000170222
ENSDART00000158846
muscle-specific beta 1 integrin binding protein
chr7_+_67467702 0.29 ENSDART00000168460
ENSDART00000170322
ribosomal protein L13
chr10_-_39130839 0.29 ENSDART00000061274
ENSDART00000148648
ribosomal protein S25
chr12_-_9132682 0.29 ENSDART00000066471
ADAM metallopeptidase domain 8b
chr16_+_25245857 0.29 ENSDART00000155220
kelch-like family member 38b
chr20_+_25445826 0.28 ENSDART00000012581
phosphoribosylformylglycinamidine synthase
chr23_+_32499916 0.28 ENSDART00000134811
si:dkey-261h17.1
chr11_-_44194132 0.28 ENSDART00000182954
ENSDART00000111271

chr18_-_11595567 0.28 ENSDART00000098565
calcium release activated channel regulator 2A
chr7_+_20031202 0.28 ENSDART00000052904
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr21_+_6114709 0.27 ENSDART00000065858
folylpolyglutamate synthase
chr19_-_46957968 0.27 ENSDART00000043713
angiopoietin 1
chr5_-_8765428 0.27 ENSDART00000167793
MYB binding protein (P160) 1a
chr12_-_33357655 0.27 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr8_+_26059677 0.26 ENSDART00000009178
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr18_+_14277003 0.26 ENSDART00000006628
zgc:173742
chr3_-_37148594 0.26 ENSDART00000140855
MLX, MAX dimerization protein
chr20_-_33705044 0.25 ENSDART00000166573
rho-associated, coiled-coil containing protein kinase 2b
chr21_+_26071874 0.24 ENSDART00000003001
ENSDART00000146573
ribosomal protein L23a
chr13_-_31370184 0.24 ENSDART00000034829
ribosomal RNA processing 12 homolog
chr20_+_37294112 0.24 ENSDART00000076293
ENSDART00000140450
connexin 23
chr21_+_21796663 0.23 ENSDART00000003518
sialidase 3 (membrane sialidase), tandem duplicate 2
chr20_-_52882881 0.23 ENSDART00000111078
wu:fi04e12
chr10_+_22034477 0.23 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
nucleophosmin 1a
chr14_+_16151636 0.23 ENSDART00000159352
polymerase (RNA) I polypeptide A
chr6_-_41536323 0.23 ENSDART00000113157
HemK methyltransferase family member 1
chr7_-_23745984 0.22 ENSDART00000048050
zgc:92429
chr9_+_12887491 0.22 ENSDART00000102386
si:ch211-167j6.4
chr14_+_16151368 0.22 ENSDART00000160973
polymerase (RNA) I polypeptide A
chr7_+_20344032 0.22 ENSDART00000144948
ENSDART00000138786
plac8 onzin related protein 1
chr16_+_40954481 0.21 ENSDART00000058587
glycogen synthase kinase binding protein
chr20_-_33704753 0.21 ENSDART00000157427
rho-associated, coiled-coil containing protein kinase 2b
chr21_-_30082414 0.21 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr7_+_6652967 0.21 ENSDART00000102681
purine nucleoside phosphorylase 5a
chr4_-_2945306 0.21 ENSDART00000128934
ENSDART00000019518
AE binding protein 2
chr5_-_32338866 0.21 ENSDART00000017956
ENSDART00000047670
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr7_-_30779575 0.20 ENSDART00000004782
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr25_-_36248053 0.20 ENSDART00000134928
nuclear factor of activated T cells 3b
chr13_-_3516473 0.19 ENSDART00000146240
parkin RBR E3 ubiquitin protein ligase
chr21_-_22122312 0.18 ENSDART00000101726
solute carrier family 35, member F2
chr8_+_15277874 0.18 ENSDART00000146965
deoxynucleotidyltransferase, terminal, interacting protein 2
chr6_-_54078623 0.18 ENSDART00000154076
hyaluronoglucosaminidase 1
chr6_-_52348562 0.18 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eukaryotic translation initiation factor 6
chr2_-_6182098 0.17 ENSDART00000156167
si:ch73-182a11.2
chr12_+_27117609 0.17 ENSDART00000076154
homeobox B8b
chr11_+_3959495 0.17 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr19_+_20201254 0.17 ENSDART00000010140
insulin-like growth factor 2 mRNA binding protein 3
chr17_-_45370200 0.17 ENSDART00000186208
zinc finger protein 106a
chr24_-_42090635 0.17 ENSDART00000166413
signal sequence receptor, alpha
chr16_-_8520474 0.17 ENSDART00000137365
growth factor receptor-bound protein 10b
chr23_+_38159715 0.17 ENSDART00000137969
zgc:112994
chr23_+_43870886 0.17 ENSDART00000102658
ENSDART00000149088
nuclear transcription factor, X-box binding-like 1
chr20_-_53996193 0.17 ENSDART00000004756
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr20_+_54666222 0.17 ENSDART00000166592

chr20_-_54259780 0.16 ENSDART00000172631
FK506 binding protein 3
chr5_-_33280699 0.16 ENSDART00000183838
kynurenine aminotransferase 1
chr11_-_16975190 0.16 ENSDART00000122222
succinate-CoA ligase, GDP-forming, beta subunit
chr12_-_30359031 0.16 ENSDART00000192628
tudor domain containing 1
chr6_-_52796212 0.16 ENSDART00000154133
recombination signal binding protein for immunoglobulin kappa J region-like
chr3_-_18805225 0.16 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr7_+_20030888 0.16 ENSDART00000192808
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr1_-_19648227 0.16 ENSDART00000054574
polymerase (RNA) I polypeptide E
chr2_+_9946121 0.16 ENSDART00000100696
TSEN15 tRNA splicing endonuclease subunit
chr11_+_6010177 0.16 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
GTP binding protein 3, mitochondrial
chr11_+_6009984 0.15 ENSDART00000185680
GTP binding protein 3, mitochondrial
chr6_-_39080630 0.15 ENSDART00000021520
ENSDART00000128308
eukaryotic translation initiation factor 4Bb
chr13_-_9061944 0.15 ENSDART00000164186
ENSDART00000102051
si:dkey-112g5.12
chr20_+_54079341 0.15 ENSDART00000060444
ribosomal protein S29
chr23_-_38160024 0.15 ENSDART00000087112
prefoldin subunit 4
chr4_-_25271455 0.15 ENSDART00000066936
transmembrane protein 110, like
chr7_-_58843193 0.15 ENSDART00000167231
mitochondrial ribosomal protein L15
chr3_+_1150348 0.15 ENSDART00000148524
nucleolar protein 12
chr17_-_49407091 0.15 ENSDART00000021950
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr4_+_2620751 0.15 ENSDART00000013924
G protein-coupled receptor 22a
chr15_-_17099560 0.15 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr22_-_26834043 0.14 ENSDART00000087202
si:dkey-44g23.5
chr16_+_16968682 0.14 ENSDART00000111074
si:ch211-120k19.1
chr5_-_30978381 0.14 ENSDART00000127787
spinster homolog 3 (Drosophila)
chr8_-_19904124 0.14 ENSDART00000129193
TraB domain containing 2B
chr20_-_40725142 0.14 ENSDART00000181279
connexin 32.2
chr16_-_54455573 0.14 ENSDART00000075275
pyruvate kinase L/R
chr17_+_24109012 0.14 ENSDART00000156251
EH domain binding protein 1
chr4_-_14192254 0.14 ENSDART00000143804
pseudouridylate synthase 7-like
chr9_+_42270043 0.13 ENSDART00000137435
si:dkey-10c21.1
chr24_+_32668675 0.13 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
chr17_-_27382826 0.13 ENSDART00000186657
ENSDART00000155986
ENSDART00000191060
ENSDART00000077608
si:ch1073-358c10.1
chr7_-_2116512 0.13 ENSDART00000098148
si:cabz01007802.1
chr7_+_17973269 0.13 ENSDART00000079969
potassium channel, subfamily K, member 7
chr7_-_50410524 0.13 ENSDART00000083346
huntingtin interacting protein K
chr13_-_25408387 0.13 ENSDART00000002741
inositol 1,4,5-trisphosphate receptor interacting protein
chr19_+_20201593 0.13 ENSDART00000163026
insulin-like growth factor 2 mRNA binding protein 3
chr17_+_36627099 0.12 ENSDART00000154104
interphotoreceptor matrix proteoglycan 1b
chr6_+_3717613 0.12 ENSDART00000184330
Sjogren syndrome antigen B (autoantigen La)
chr1_-_55750208 0.12 ENSDART00000142244
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr13_-_35892051 0.12 ENSDART00000145884
transforming, acidic coiled-coil containing protein 3
chr16_+_16969060 0.12 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
ribosomal protein L18
chr6_-_18531349 0.12 ENSDART00000160693
ENSDART00000169780
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr25_+_3231812 0.12 ENSDART00000163647
methionyl aminopeptidase 2b
chr12_-_20350629 0.12 ENSDART00000066384
hemoglobin beta embryonic-2
chr10_+_428269 0.12 ENSDART00000140715
zinc finger, DHHC-type containing 8a
chr24_+_23791758 0.12 ENSDART00000066655
ENSDART00000146580
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr14_+_94946 0.12 ENSDART00000165766
ENSDART00000163778
minichromosome maintenance complex component 7
chr10_+_35002786 0.11 ENSDART00000099552
exosome component 8
chr18_-_5850683 0.11 ENSDART00000082087
NIP7, nucleolar pre-rRNA processing protein
chr1_-_40015782 0.11 ENSDART00000157425
ENSDART00000159238
cyclin-dependent kinase 2 associated protein 2
chr20_+_25626479 0.11 ENSDART00000143883
phosphoribosyl pyrophosphate amidotransferase
chr19_-_35229336 0.11 ENSDART00000054274
microtubule-actin crosslinking factor 1a
chr20_-_26531850 0.11 ENSDART00000183317
ENSDART00000131994
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr10_+_29849977 0.11 ENSDART00000180242
heat shock protein 8
chr1_+_29664336 0.11 ENSDART00000088290
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b
chr7_+_1550966 0.11 ENSDART00000177863
ENSDART00000126840
SPT16 homolog, facilitates chromatin remodeling subunit
chr1_+_45925365 0.11 ENSDART00000144245
eukaryotic translation initiation factor 5B
chr21_-_35853245 0.11 ENSDART00000172245
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr16_-_10223741 0.11 ENSDART00000188099
si:rp71-15i12.1
chr1_-_54972170 0.11 ENSDART00000150548
ENSDART00000038330
KH-type splicing regulatory protein
chr3_+_28939759 0.10 ENSDART00000141904
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr10_+_29850330 0.10 ENSDART00000168898
heat shock protein 8
chr14_-_5407118 0.10 ENSDART00000168074
polycomb group ring finger 1
chr14_-_12822 0.10 ENSDART00000180650
ENSDART00000188819
muscle segment homeobox 1a
chr8_-_52859301 0.10 ENSDART00000162004
nuclear receptor subfamily 5, group A, member 1a
chr24_+_16905188 0.10 ENSDART00000066760
chaperonin containing TCP1, subunit 5 (epsilon)
chr12_+_13091842 0.10 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr22_-_36690742 0.10 ENSDART00000017188
ENSDART00000124698
nucleolin
chr11_+_25485774 0.10 ENSDART00000026249
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr17_-_29771639 0.10 ENSDART00000086201
Usher syndrome 2A (autosomal recessive, mild)
chr13_+_25761279 0.10 ENSDART00000177818
ENSDART00000002863
neurogenin 3
chr9_+_38158570 0.10 ENSDART00000059549
ENSDART00000133060
nucleolar protein interacting with the FHA domain of MKI67
chr14_+_94603 0.10 ENSDART00000162480
minichromosome maintenance complex component 7
chr5_-_55914268 0.10 ENSDART00000014049
WD repeat domain 36
chr13_-_4223955 0.10 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr2_-_48171112 0.10 ENSDART00000156258
phosphofructokinase, platelet b
chr2_-_17393971 0.09 ENSDART00000100201
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr15_-_43978141 0.09 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr1_+_44390470 0.09 ENSDART00000100321
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr20_+_38257766 0.09 ENSDART00000147485
ENSDART00000149160
chemokine (C-C motif) ligand 38, duplicate 6
chr21_-_41147818 0.09 ENSDART00000167339
ENSDART00000192730
muscle segment homeobox 2b
chr14_+_5385855 0.09 ENSDART00000031508
ladybird homeobox 2
chr3_+_58379450 0.09 ENSDART00000155759
short chain dehydrogenase/reductase family 42E, member 2
chr2_-_24369087 0.09 ENSDART00000081237
plasmalemma vesicle associated protein a
chr24_-_38192003 0.09 ENSDART00000109975
C-reactive protein 7
chr14_+_14836468 0.09 ENSDART00000166728
si:dkey-102m7.3
chr5_-_16475374 0.09 ENSDART00000134274
ENSDART00000136004
piwi-like RNA-mediated gene silencing 2
chr5_-_54195084 0.09 ENSDART00000171811
G protein-coupled receptor kinase 1 b
chr22_-_5099824 0.09 ENSDART00000122341
ENSDART00000161345
zinc finger RNA binding protein 2
chr23_+_36122058 0.08 ENSDART00000184448
homeobox C3a
chr21_-_30408775 0.08 ENSDART00000101037
NHP2 ribonucleoprotein homolog (yeast)
chr6_-_39653972 0.08 ENSDART00000155859
La ribonucleoprotein domain family, member 4Ab
chr13_+_30572172 0.08 ENSDART00000010052
ENSDART00000144417
peptidylprolyl isomerase Fa
chr21_+_38638979 0.08 ENSDART00000143373
RNA binding motif protein, X-linked 2
chr24_+_34069675 0.08 ENSDART00000143995
si:ch211-190p8.2
chr24_-_16904803 0.08 ENSDART00000165972
ENSDART00000149974
ENSDART00000149706
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr3_-_41791178 0.08 ENSDART00000049687
galectin-related inter-fiber protein
chr13_-_35907768 0.08 ENSDART00000147522
MYCL proto-oncogene, bHLH transcription factor a
chr13_+_48359573 0.08 ENSDART00000161959
ENSDART00000165311
mutS homolog 6 (E. coli)
chr15_-_1484795 0.08 ENSDART00000129356
si:dkeyp-97b10.3
chr9_-_30259295 0.08 ENSDART00000139106
si:dkey-100n23.5
chr2_+_30547018 0.08 ENSDART00000193747
ankyrin repeat domain 33Bb
chr9_+_41821613 0.08 ENSDART00000097295
collagen type XVIII alpha 1 chain a
chr24_+_36317544 0.08 ENSDART00000048640
ENSDART00000156096
pseudouridylate synthase 3
chr13_+_30912385 0.08 ENSDART00000182642
dorsal root ganglia homeobox
chr1_+_45925150 0.08 ENSDART00000074689
eukaryotic translation initiation factor 5B

Network of associatons between targets according to the STRING database.

First level regulatory network of myca+mych

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030521 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.4 GO:0021985 neurohypophysis development(GO:0021985)
0.1 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.4 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.7 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.2 GO:1902626 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.7 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0045428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0 0.1 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.3 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.0 0.2 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0046385 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) 2'-deoxyribonucleotide biosynthetic process(GO:0009265) deoxyribose phosphate biosynthetic process(GO:0046385)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.6 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.2 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.0 0.2 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0061333 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.0 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.0 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.1 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.3 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.1 0.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.2 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.2 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.4 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 0.7 GO:0070888 E-box binding(GO:0070888)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.7 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.1 0.5 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.2 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.2 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.2 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.0 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.3 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.1 GO:0032138 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.0 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling