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PRJNA207719: Tissue specific transcriptome profiling

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Results for nfe2l1b+nfe2l2b

Z-value: 0.92

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Transcription factors associated with nfe2l1b+nfe2l2b

Gene Symbol Gene ID Gene Info
ENSDARG00000076533 nuclear factor, erythroid 2-like 1b
ENSDARG00000089697 nuclear factor, erythroid 2-like 2b
ENSDARG00000114820 nuclear factor, erythroid 2-like 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfe2l1bdr11_v1_chr12_+_28854410_28854410-0.903.6e-02Click!
nfe2l2bdr11_v1_chr6_-_10902916_10902916-0.049.5e-01Click!

Activity profile of nfe2l1b+nfe2l2b motif

Sorted Z-values of nfe2l1b+nfe2l2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_59104145 0.74 ENSDART00000132495
ENSDART00000152457
si:zfos-2330d3.1
si:zfos-2330d3.7
chr12_+_20336070 0.72 ENSDART00000066385
zgc:163057
chr1_+_26411496 0.71 ENSDART00000112263
Rho guanine nucleotide exchange factor (GEF) 38
chr22_+_19220459 0.71 ENSDART00000163070
si:dkey-21e2.7
chr7_+_38750871 0.65 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
coagulation factor II (thrombin)
chr24_-_38192003 0.57 ENSDART00000109975
C-reactive protein 7
chr7_+_2455344 0.55 ENSDART00000172942
si:dkey-125e8.4
chr1_-_33645967 0.55 ENSDART00000192758
claudin g
chr22_-_17677947 0.54 ENSDART00000139911
tight junction protein 3
chr5_+_57924611 0.53 ENSDART00000050949
B-cell translocation gene 4
chr6_+_13201358 0.52 ENSDART00000190290

chr13_-_4223955 0.51 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr3_+_5083407 0.51 ENSDART00000146883
si:ch73-338o16.4
chr14_+_21107032 0.50 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldolase b, fructose-bisphosphate
chr22_+_38229321 0.49 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
chr9_+_23770666 0.49 ENSDART00000182493
si:ch211-219a4.3
chr5_-_63509581 0.49 ENSDART00000097325
complement component 5
chr3_-_32541033 0.48 ENSDART00000151476
ENSDART00000055324
reticulocalbin 3, EF-hand calcium binding domain
chr2_+_11031360 0.48 ENSDART00000180020
ENSDART00000145093
acyl-CoA thioesterase 11a
chr20_+_26538137 0.46 ENSDART00000045397
syntaxin 11b, tandem duplicate 1
chr10_+_28428222 0.45 ENSDART00000135003
si:ch211-222e20.4
chr24_-_27452488 0.45 ENSDART00000136433
chemokine (C-C motif) ligand 34b, duplicate 8
chr8_+_554531 0.45 ENSDART00000193623

chr6_+_584632 0.45 ENSDART00000151150
zgc:92360
chr2_+_1486822 0.44 ENSDART00000132500
complement component 8, alpha polypeptide
chr20_-_25518488 0.43 ENSDART00000186993
cytochrome P450, family 2, subfamily N, polypeptide 13
chr23_+_44049509 0.43 ENSDART00000102003
TXK tyrosine kinase
chr6_-_55297274 0.43 ENSDART00000184283
ubiquitin-conjugating enzyme E2C
chr14_-_1280907 0.42 ENSDART00000186150

chr21_-_42876565 0.42 ENSDART00000126480
zmp:0000001268
chr8_+_42718135 0.42 ENSDART00000158900
zgc:194007
chr14_-_970853 0.41 ENSDART00000130801
acyl-CoA synthetase long chain family member 1b
chr1_-_45157243 0.40 ENSDART00000131882
mucin, multiple PTS and SEA group, member 1
chr7_+_22767678 0.40 ENSDART00000137203
plac8 onzin related protein 6
chr8_+_32402441 0.40 ENSDART00000191451
epithelial mitogen homolog (mouse)
chr16_+_21426524 0.40 ENSDART00000182869
gasdermin Eb
chr21_-_22435957 0.39 ENSDART00000137959
interleukin 7 receptor
chr11_+_37216668 0.38 ENSDART00000173076
zgc:112265
chr24_-_10006158 0.38 ENSDART00000106244
zgc:171750
chr16_-_36905789 0.38 ENSDART00000102212
tyrosyl-DNA phosphodiesterase 2a
chr25_-_16554757 0.38 ENSDART00000154480
si:ch211-266k8.6
chr19_-_10330778 0.38 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
coiled-coil domain containing 106b
chr5_+_29794058 0.37 ENSDART00000045410
Thy-1 cell surface antigen
chr14_-_14659023 0.37 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
NAD(P) dependent steroid dehydrogenase-like
chr15_+_9117330 0.37 ENSDART00000156306
prostaglandin I2 receptor
chr17_-_6198823 0.37 ENSDART00000028407
ENSDART00000193636
protein tyrosine kinase 2 beta, a
chr18_+_7553950 0.36 ENSDART00000193420
ENSDART00000062143
zgc:77650
chr7_+_34786591 0.36 ENSDART00000173700
si:dkey-148a17.5
chr16_-_51288178 0.36 ENSDART00000079864
zgc:173729
chr8_-_2506327 0.36 ENSDART00000101125
ENSDART00000125124
ribosomal protein L6
chr7_+_25036188 0.36 ENSDART00000163957
ENSDART00000169749
sb:cb1058
chr7_-_5316901 0.36 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
chr12_+_4900981 0.35 ENSDART00000171507
CD79b molecule, immunoglobulin-associated beta
chr7_-_7398350 0.35 ENSDART00000012637
zgc:101810
chr9_+_23714406 0.34 ENSDART00000189445
glycophorin C (Gerbich blood group)
chr1_-_45320126 0.34 ENSDART00000133572
si:ch73-90k17.1
chr7_-_73815262 0.34 ENSDART00000185351
zgc:165555
chr8_+_13389115 0.33 ENSDART00000184428
ENSDART00000154266
ENSDART00000049469
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
chr2_+_37207461 0.33 ENSDART00000138952
ENSDART00000132856
ENSDART00000137272
ENSDART00000143468
apolipoprotein Da, duplicate 2
chr8_-_29677300 0.33 ENSDART00000032407
ENSDART00000143623
perforin 1.6
chr21_-_5881344 0.32 ENSDART00000009241
ribosomal protein L35
chr16_-_29714540 0.32 ENSDART00000067854
tumor necrosis factor, alpha-induced protein 8-like 2b
chr7_+_49695904 0.32 ENSDART00000183550
ENSDART00000126991
achaete-scute family bHLH transcription factor 1b
chr16_-_22192006 0.32 ENSDART00000163338
interleukin 6 receptor
chr3_-_16784280 0.32 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
chr22_-_5744491 0.32 ENSDART00000145014
BCDIN3 domain containing
chr2_-_38035235 0.32 ENSDART00000075904
cerebellin 5
chr8_-_10932206 0.31 ENSDART00000124313
nuclear receptor subfamily 1, group H, member 5
chr22_+_3156386 0.31 ENSDART00000161212
ribosomal protein L36
chr23_+_39695827 0.31 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr7_-_28658143 0.31 ENSDART00000173556
adhesion G protein-coupled receptor G1
chr3_-_27647845 0.31 ENSDART00000151625
si:ch211-157c3.4
chr25_+_469855 0.31 ENSDART00000104717
ribosomal L24 domain containing 1
chr6_-_46589726 0.31 ENSDART00000084334
prostaglandin I2 (prostacyclin) synthase
chr21_+_35289469 0.31 ENSDART00000155140
interleukin 12B, b
chr4_+_77948517 0.30 ENSDART00000149305
protein kinase C and casein kinase substrate in neurons 2
chr6_-_49526510 0.30 ENSDART00000128025
ribosomal protein S26, like
chr10_+_29852677 0.30 ENSDART00000141549
heat shock protein 8
chr1_-_59252973 0.30 ENSDART00000167061
si:ch1073-286c18.5
chr20_-_30370884 0.30 ENSDART00000062429
allantoicase
chr15_-_41714329 0.30 ENSDART00000154113

chr4_+_30785713 0.29 ENSDART00000165945
si:dkey-178j11.5
chr3_-_34107685 0.29 ENSDART00000151130
immunoglobulin heavy variable 4-3
chr6_+_392815 0.29 ENSDART00000163142
cytohesin 4b
chr17_+_24684778 0.29 ENSDART00000146309
ENSDART00000082237
zinc finger protein 593
chr3_+_3545825 0.29 ENSDART00000109060

chr17_-_45104750 0.29 ENSDART00000075520
aldehyde dehydrogenase 6 family, member A1
chr18_-_5209258 0.28 ENSDART00000183109

chr17_+_27456804 0.28 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr24_+_34806822 0.28 ENSDART00000148407
ENSDART00000188328
melanin-concentrating hormone receptor 2
chr18_-_43866001 0.28 ENSDART00000150218
trehalase (brush-border membrane glycoprotein)
chr16_+_30604387 0.28 ENSDART00000058785
family with sequence similarity 210, member Ab
chr1_-_53880639 0.28 ENSDART00000010543
LTV1 ribosome biogenesis factor
chr2_-_24069331 0.28 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
solute carrier family 12 (potassium/chloride transporter), member 7a
chr6_-_52675630 0.28 ENSDART00000083830
syndecan 4
chr7_+_33172066 0.28 ENSDART00000174013
si:ch211-194p6.12
chr15_-_44052927 0.28 ENSDART00000166209
wu:fb44b02
chr2_+_3881000 0.28 ENSDART00000081897
membrane protein, palmitoylated 7b (MAGUK p55 subfamily member 7)
chr1_+_57145072 0.27 ENSDART00000152776
si:ch73-94k4.4
chr7_+_49654588 0.27 ENSDART00000025451
ENSDART00000141934
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr7_+_9008372 0.27 ENSDART00000144897

chr4_+_39766931 0.27 ENSDART00000138663
si:dkeyp-85d8.1
chr3_-_55139127 0.27 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr15_+_5973909 0.27 ENSDART00000126886
ENSDART00000189618
immunoglobulin superfamily, member 5b
chr25_-_37322081 0.27 ENSDART00000128285
immunoglobulin light 4 variable 10
chr11_+_44622472 0.27 ENSDART00000159068
ENSDART00000166323
ENSDART00000187753
RNA binding motif protein 34
chr17_+_28103675 0.27 ENSDART00000188078
zgc:91908
chr4_+_306036 0.26 ENSDART00000103659
mesogenin 1
chr3_+_4225128 0.26 ENSDART00000154345
si:dkey-175d9.1
chr1_+_55662491 0.26 ENSDART00000152386
adhesion G protein-coupled receptor E8
chr25_+_29472361 0.26 ENSDART00000154857
interleukin 17 receptor E-like
chr25_+_31227747 0.26 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr8_-_32385989 0.26 ENSDART00000143716
ENSDART00000098850
lipase, endothelial
chr22_+_30543437 0.26 ENSDART00000137983
si:dkey-103k4.1
chr20_-_38746889 0.26 ENSDART00000140275
tripartite motif containing 54
chr7_+_4987530 0.26 ENSDART00000132983
ENSDART00000137067
si:dkey-81n2.1
chr13_+_16279890 0.25 ENSDART00000101775
ENSDART00000057948
annexin A11a
chr23_+_32039386 0.25 ENSDART00000133801
myosin light chain kinase 2
chr3_-_29508959 0.25 ENSDART00000055408
cytohesin 4a
chr21_+_1647990 0.25 ENSDART00000148540
ferrochelatase
chr20_+_35473288 0.25 ENSDART00000047195
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1
chr18_+_44673990 0.25 ENSDART00000018625
N-ethylmaleimide-sensitive factor attachment protein, alpha b
chr24_-_26485098 0.25 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eukaryotic translation initiation factor 5A
chr13_-_42560662 0.25 ENSDART00000124898

chr7_-_2292403 0.25 ENSDART00000075856
zgc:66473
chr25_-_35139520 0.24 ENSDART00000189008

chr23_+_4890693 0.24 ENSDART00000023537
troponin C type 1a (slow)
chr25_+_15939275 0.24 ENSDART00000126641
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr21_-_20840714 0.24 ENSDART00000144861
ENSDART00000139430
complement component 6
chr23_-_26536055 0.24 ENSDART00000182719
si:dkey-205h13.2
chr14_-_38843690 0.24 ENSDART00000183629
spindle apparatus coiled-coil protein 1
chr21_-_7035599 0.24 ENSDART00000139777
si:ch211-93g21.1
chr22_+_19277361 0.24 ENSDART00000190075
ENSDART00000141097
ENSDART00000136943
si:dkey-21e2.13
chr10_+_14982977 0.24 ENSDART00000140869
si:dkey-88l16.3
chr14_+_4151379 0.24 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr22_-_23006842 0.23 ENSDART00000105607
protein tyrosine phosphatase, receptor type, C
chr24_-_25098719 0.23 ENSDART00000193651
pleckstrin homology-like domain, family B, member 2b
chr20_-_43079478 0.23 ENSDART00000060982
sorting nexin 9b
chr3_-_8012847 0.23 ENSDART00000169673
si:ch211-175l6.1
chr20_-_3290791 0.23 ENSDART00000146870
si:ch1073-412h12.3
chr20_+_48754045 0.23 ENSDART00000062578
zgc:110348
chr15_-_36357889 0.23 ENSDART00000156377
si:dkey-23k10.5
chr25_+_753364 0.23 ENSDART00000183804
twinfilin actin binding protein 1
chr19_+_15441022 0.23 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr1_-_8963484 0.23 ENSDART00000188035
suppressor of cytokine signaling 1b
chr18_-_43866526 0.23 ENSDART00000111309
trehalase (brush-border membrane glycoprotein)
chr1_-_43933271 0.23 ENSDART00000121605
secretory calcium-binding phosphoprotein 6
chr23_-_4404105 0.22 ENSDART00000146941
si:ch73-142c19.1
chr12_+_48841419 0.22 ENSDART00000125331
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr8_-_554540 0.22 ENSDART00000163934
Danio rerio uncharacterized LOC100329294 (LOC100329294), mRNA.
chr3_+_22375596 0.22 ENSDART00000188243
ENSDART00000181506
Rho GTPase activating protein 27, like
chr9_-_29579908 0.22 ENSDART00000140876
centromere protein J
chr15_-_17099560 0.22 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr3_-_32603191 0.22 ENSDART00000150997
si:ch73-248e21.7
chr1_-_59141715 0.22 ENSDART00000164941
ENSDART00000138870
si:ch1073-110a20.1
chr5_+_33519943 0.22 ENSDART00000131316
membrane-spanning 4-domains, subfamily A, member 17C.1
chr22_+_8979955 0.22 ENSDART00000144005
si:ch211-213a13.1
chr9_+_426392 0.22 ENSDART00000172515
basic leucine zipper and W2 domains 1b
chr13_+_33688474 0.22 ENSDART00000161465

chr25_+_37443194 0.21 ENSDART00000163178
ENSDART00000190262
solute carrier family 10, member 3
chr10_+_23511816 0.21 ENSDART00000127255
zmp:0000000924
chr22_+_22010128 0.21 ENSDART00000172610
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 2
chr22_+_19289970 0.21 ENSDART00000137976
ENSDART00000132386
si:dkey-21e2.15
chr7_-_5029478 0.21 ENSDART00000193819
leukotriene B4 receptor
chr3_-_40162843 0.21 ENSDART00000129664
ENSDART00000025285
developmentally regulated GTP binding protein 2
chr15_-_1745408 0.21 ENSDART00000182311
syntaxin 1A (brain)
chr24_+_12945803 0.21 ENSDART00000005105
proteasome activator subunit 1
chr25_+_36347126 0.21 ENSDART00000152449
si:ch211-113a14.22
chr4_-_11403811 0.20 ENSDART00000067272
ENSDART00000140018
Pim proto-oncogene, serine/threonine kinase, related 173
chr15_+_36105581 0.20 ENSDART00000184099
collagen, type IV, alpha 3
chr3_-_14695033 0.20 ENSDART00000133850
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr11_+_6009984 0.20 ENSDART00000185680
GTP binding protein 3, mitochondrial
chr15_-_4037626 0.20 ENSDART00000160905
purinergic receptor P2Y14
chr10_+_39248911 0.20 ENSDART00000170079
ENSDART00000167974
FAD-dependent oxidoreductase domain containing 1
chr3_-_34078179 0.20 ENSDART00000191687
immunoglobulin heavy variable 6-2
chr12_-_4593610 0.20 ENSDART00000110104
interferon regulatory factor 3
chr5_+_63288599 0.20 ENSDART00000140065
si:ch73-37h15.2
chr22_-_968484 0.20 ENSDART00000105895
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr12_-_3962372 0.20 ENSDART00000016791
eukaryotic translation initiation factor 3, subunit C
chr25_-_28926330 0.20 ENSDART00000155173
electron transfer flavoprotein beta subunit lysine methyltransferase
chr20_+_25581627 0.20 ENSDART00000030229
cytochrome P450, family 2, subfamily P, polypeptide 9
chr16_-_55259199 0.20 ENSDART00000161130
IQ motif containing GTPase activating protein 3
chr22_-_15577060 0.20 ENSDART00000176291
hematopoietic SH2 domain containing
chr4_-_9592402 0.19 ENSDART00000114060
cerebral dopamine neurotrophic factor
chr23_+_32044410 0.19 ENSDART00000048628
myosin light chain kinase 2
chr7_+_2245815 0.19 ENSDART00000114434
si:ch211-285c6.4
chr10_-_1961576 0.19 ENSDART00000042441
teratocarcinoma-derived growth factor 1
chr5_-_67471375 0.19 ENSDART00000147009
si:dkey-251i10.2
chr3_-_39171968 0.19 ENSDART00000154494
si:dkeyp-57f11.2
chr3_+_30501135 0.19 ENSDART00000165869
si:dkey-13n23.3
chr8_+_25615781 0.19 ENSDART00000062385
solute carrier family 38, member 5a
chr4_+_37952218 0.19 ENSDART00000186865
si:dkeyp-82b4.2
chr8_-_20243389 0.19 ENSDART00000184904
alkaline ceramidase 1
chr8_+_32406885 0.19 ENSDART00000167600
epithelial mitogen homolog (mouse)
chr4_+_5249494 0.19 ENSDART00000150391
si:ch211-214j24.14
chr18_-_7539469 0.19 ENSDART00000101296
si:dkey-30c15.2
chr25_-_13050959 0.19 ENSDART00000169041
chemokine (C-C motif) ligand 35, duplicate 1
chr23_-_270847 0.19 ENSDART00000191867
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr6_-_9922266 0.18 ENSDART00000151549
Pim proto-oncogene, serine/threonine kinase, related 73
chr4_-_30174588 0.18 ENSDART00000135420
ENSDART00000004188
si:dkey-265e15.5

Network of associatons between targets according to the STRING database.

First level regulatory network of nfe2l1b+nfe2l2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2 0.5 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.8 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.3 GO:0000256 allantoin catabolic process(GO:0000256)
0.1 0.2 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.1 0.3 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.1 0.4 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.2 GO:1905133 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.3 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.1 0.2 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 0.3 GO:0030101 natural killer cell activation(GO:0030101)
0.1 0.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.5 GO:0030104 water homeostasis(GO:0030104)
0.1 0.4 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1 0.3 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.3 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 1.0 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.3 GO:0006210 thymine catabolic process(GO:0006210) valine catabolic process(GO:0006574) thymine metabolic process(GO:0019859)
0.0 0.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.2 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 1.0 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.2 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.0 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0061511 centriole elongation(GO:0061511)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.3 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.4 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.2 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.2 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.8 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.7 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0035909 establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.1 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.6 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 1.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.0 GO:0042662 ventricular compact myocardium morphogenesis(GO:0003223) negative regulation of mesodermal cell fate specification(GO:0042662)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910) positive regulation of B cell activation(GO:0050871)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.3 GO:0007568 aging(GO:0007568)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.3 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0030428 cell septum(GO:0030428)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.4 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.0 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.3 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.1 0.2 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.8 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.4 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.7 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.7 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0070697 activin receptor binding(GO:0070697)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.0 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.0 2.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.5 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.1 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL