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PRJNA207719: Tissue specific transcriptome profiling

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Results for nfil3-4+si:dkey-172o19.2

Z-value: 1.31

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Transcription factors associated with nfil3-4+si:dkey-172o19.2

Gene Symbol Gene ID Gene Info
ENSDARG00000071398 si_dkey-172o19.2
ENSDARG00000092346 nuclear factor, interleukin 3 regulated, member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:dkey-172o19.2dr11_v1_chr22_+_20546612_205466120.533.6e-01Click!
nfil3-4dr11_v1_chr22_+_20560041_205600410.316.1e-01Click!

Activity profile of nfil3-4+si:dkey-172o19.2 motif

Sorted Z-values of nfil3-4+si:dkey-172o19.2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_12725513 1.01 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr19_+_7735157 0.98 ENSDART00000186717
tuftelin 1b
chr11_+_43419809 0.79 ENSDART00000172982
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr25_-_13188678 0.79 ENSDART00000125754
si:ch211-147m6.1
chr14_+_3507326 0.75 ENSDART00000159326
glutathione S-transferase pi 1
chr22_+_11775269 0.68 ENSDART00000140272
keratin 96
chr8_-_21103041 0.67 ENSDART00000171771
ENSDART00000131322
ENSDART00000137838
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr7_+_31871830 0.67 ENSDART00000139899
myosin binding protein C, cardiac
chr10_+_20256454 0.67 ENSDART00000111097
transcriptional and immune response regulator
chr9_-_45602978 0.62 ENSDART00000139019
ENSDART00000085763
anterior gradient 1
chr10_+_22771176 0.60 ENSDART00000192046
transmembrane protein 88 a
chr5_+_43782267 0.59 ENSDART00000130355
nitric oxide synthase 2a, inducible
chr19_-_31372896 0.59 ENSDART00000046609
scinderin
chr6_+_53288018 0.58 ENSDART00000170319
cysteinyl leukotriene receptor 3
chr8_-_21103522 0.57 ENSDART00000100283
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr16_+_23487051 0.57 ENSDART00000145496
ictacalcin 2
chr5_-_2112030 0.56 ENSDART00000091932
glucuronidase, beta
chr5_+_29831235 0.56 ENSDART00000109660
F11 receptor, tandem duplicate 1
chr17_+_26965351 0.56 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr20_-_25533739 0.56 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr16_+_40954481 0.55 ENSDART00000058587
glycogen synthase kinase binding protein
chr4_-_12914163 0.55 ENSDART00000140002
ENSDART00000145917
ENSDART00000141355
ENSDART00000067135
methionine sulfoxide reductase B3
chr6_+_8129543 0.55 ENSDART00000011724
Kruppel-like factor 1 (erythroid)
chr8_-_8346023 0.54 ENSDART00000164731
ENSDART00000188259
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr7_-_12968689 0.54 ENSDART00000173115
ENSDART00000013690
ribosomal protein, large P2, like
chr2_-_55779927 0.53 ENSDART00000168579

chr20_-_26551210 0.52 ENSDART00000077715
si:dkey-25e12.3
chr14_+_48862987 0.50 ENSDART00000167810
zgc:154054
chr12_+_5708400 0.50 ENSDART00000017191
distal-less homeobox 3b
chr13_+_33688474 0.49 ENSDART00000161465

chr21_+_25221940 0.49 ENSDART00000108972
syncollin, tandem duplicate 1
chr22_+_980290 0.49 ENSDART00000065377
differentially expressed in FDCP 6b homolog (mouse)
chr16_+_23398369 0.48 ENSDART00000037694
S100 calcium binding protein A10b
chr7_-_24364536 0.48 ENSDART00000064789
thioredoxin
chr16_+_23397785 0.48 ENSDART00000148961
S100 calcium binding protein A10b
chr15_-_5016039 0.47 ENSDART00000156458
defensin, beta-like 3
chr23_+_11285662 0.47 ENSDART00000111028
cell adhesion molecule L1-like a
chr13_-_36034582 0.47 ENSDART00000133565
si:dkey-157l19.2
chr6_+_42475730 0.47 ENSDART00000150226
macrophage stimulating 1 receptor a
chr1_+_14253118 0.47 ENSDART00000161996
chemokine (C-X-C motif) ligand 8a
chr17_-_2039511 0.46 ENSDART00000160223
serine peptidase inhibitor, Kunitz type 1 a
chr17_-_20236228 0.46 ENSDART00000136490
ENSDART00000029380
BCL2 interacting protein 4
chr5_+_22974019 0.45 ENSDART00000147157
ENSDART00000020434
bromodomain and WD repeat domain containing 3
chr9_+_38292947 0.45 ENSDART00000146663
transcription factor CP2-like 1
chr3_-_34022076 0.45 ENSDART00000150907
ENSDART00000151092
immunoglobulin heavy variable 1-4
immunoglobulin heavy variable 1-4
chr4_+_5537101 0.45 ENSDART00000008692
si:dkey-14d8.7
chr22_+_5478353 0.44 ENSDART00000160596
tubulin polymerization promoting protein
chr14_-_12071447 0.44 ENSDART00000166116
thymosin beta 1
chr18_+_16943911 0.44 ENSDART00000157609
si:dkey-8l13.5
chr7_+_56577522 0.44 ENSDART00000149130
ENSDART00000149624
haptoglobin
chr5_+_15202495 0.44 ENSDART00000144915
T-box 1
chr25_+_34014523 0.44 ENSDART00000182856
annexin A2a
chr22_-_15593824 0.43 ENSDART00000123125
tropomyosin 4a
chr10_+_36650222 0.43 ENSDART00000126963
uncoupling protein 3
chr6_-_26895750 0.43 ENSDART00000011863
high density lipoprotein binding protein a
chr4_+_5531583 0.43 ENSDART00000137500
ENSDART00000042080
si:dkey-14d8.6
chr17_-_52091999 0.43 ENSDART00000019766
transforming growth factor, beta 3
chr7_+_21787507 0.43 ENSDART00000100936
transmembrane protein 88 b
chr1_+_24355515 0.42 ENSDART00000051763
ribosomal protein S3A
chr22_-_817479 0.42 ENSDART00000123487
zgc:153675
chr7_-_51773166 0.42 ENSDART00000054591
bone morphogenetic protein 15
chr24_+_38671054 0.42 ENSDART00000154214
si:ch73-70c5.1
chr7_+_12950507 0.42 ENSDART00000067629
ENSDART00000158004
serum amyloid A
chr16_+_23984755 0.42 ENSDART00000145328
apolipoprotein C-II
chr7_+_39706004 0.42 ENSDART00000161856
chemokine (C-C motif) ligand 36, duplicate 1
chr8_-_36475328 0.42 ENSDART00000048448
si:busm1-266f07.2
chr2_-_39017838 0.42 ENSDART00000048838
retinol binding protein 2b, cellular
chr24_+_16983269 0.42 ENSDART00000139176
ENSDART00000023833
eukaryotic translation initiation factor 2, subunit 3 gamma
chr3_+_49043917 0.42 ENSDART00000158212
zgc:92161
chr16_+_29492749 0.41 ENSDART00000179680
cathepsin K
chr9_-_48736388 0.41 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr7_+_30392613 0.41 ENSDART00000075508
lipase, hepatic a
chr14_+_4151379 0.41 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr16_-_14587332 0.41 ENSDART00000012479
DNA replication and sister chromatid cohesion 1
chr4_+_39766931 0.41 ENSDART00000138663
si:dkeyp-85d8.1
chr21_+_1647990 0.41 ENSDART00000148540
ferrochelatase
chr25_+_13191391 0.40 ENSDART00000109937
si:ch211-147m6.2
chr6_+_50451337 0.40 ENSDART00000155051
myelocytomatosis oncogene homolog
chr9_+_41224100 0.40 ENSDART00000141792
signal transducer and activator of transcription 1b
chr7_-_60831082 0.40 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr14_-_7786260 0.40 ENSDART00000128218
transmembrane protein 173
chr7_-_3429874 0.40 ENSDART00000132330
si:ch211-285c6.1
chr5_+_45677781 0.40 ENSDART00000163120
ENSDART00000126537
group-specific component (vitamin D binding protein)
chr16_-_26140768 0.39 ENSDART00000143960
CD79a molecule, immunoglobulin-associated alpha
chr14_+_1170968 0.39 ENSDART00000125203
ENSDART00000193575
HOP homeobox
chr3_-_32956808 0.39 ENSDART00000183902
caspase 6, apoptosis-related cysteine peptidase, like 1
chr10_+_38417512 0.39 ENSDART00000112457
SAM domain, SH3 domain and nuclear localisation signals 1b
chr14_-_970853 0.39 ENSDART00000130801
acyl-CoA synthetase long chain family member 1b
chr19_-_15192638 0.39 ENSDART00000048151
phosphatase and actin regulator 4a
chr4_-_26107841 0.39 ENSDART00000172012
si:ch211-244b2.4
chr25_+_13191615 0.39 ENSDART00000168849
si:ch211-147m6.2
chr12_-_20373058 0.39 ENSDART00000066382
aquaporin 8a, tandem duplicate 1
chr3_+_29641181 0.39 ENSDART00000151517
eukaryotic translation initiation factor 3, subunit D
chr2_-_41861040 0.39 ENSDART00000045763
kelch-like ECH-associated protein 1a
chr19_-_15177324 0.38 ENSDART00000169883
phosphatase and actin regulator 4a
chr4_+_391297 0.38 ENSDART00000030215
ribosomal protein L18a
chr20_+_25586099 0.38 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr15_-_41689981 0.38 ENSDART00000059327
splA/ryanodine receptor domain and SOCS box containing 4b
chr21_+_25625026 0.38 ENSDART00000134678
ovo-like zinc finger 1b
chr10_+_26667475 0.37 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
chr14_+_15620640 0.37 ENSDART00000188867
si:dkey-203a12.9
chr4_+_76608793 0.37 ENSDART00000141114
membrane-spanning 4-domains, subfamily A, member 17A.8
chr10_-_15053507 0.37 ENSDART00000157446
ENSDART00000170441
si:ch211-95j8.5
chr12_+_34258139 0.37 ENSDART00000153127
suppressor of cytokine signaling 3b
chr1_+_51475094 0.37 ENSDART00000146352
Meis homeobox 1 a
chr7_+_15736230 0.37 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr1_+_55137943 0.37 ENSDART00000138070
ENSDART00000150510
ENSDART00000133472
ENSDART00000136378
myoglobin
chr13_-_25774183 0.37 ENSDART00000046981
PDZ and LIM domain 1 (elfin)
chr20_+_2039518 0.37 ENSDART00000043157

chr19_+_4990496 0.37 ENSDART00000151050
ENSDART00000017535
zgc:91968
chr21_-_17290941 0.37 ENSDART00000147993
growth factor independent 1B transcription repressor
chr17_+_25833947 0.36 ENSDART00000044328
ENSDART00000154604
acyl-CoA synthetase short chain family member 1
chr3_+_30921246 0.36 ENSDART00000076850
claudin i
chr16_-_51299061 0.36 ENSDART00000148677
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr6_-_60020385 0.36 ENSDART00000169990
ENSDART00000167740
ENSDART00000098247
WW domain binding protein 4
chr4_+_73651452 0.36 ENSDART00000174164
zinc finger protein 989
chr10_-_22095505 0.36 ENSDART00000140210
plac8 onzin related protein 10
chr5_-_65037525 0.36 ENSDART00000158856
annexin A1b
chr18_+_50650713 0.36 ENSDART00000159095
si:dkey-151j17.4
chr5_-_65037371 0.36 ENSDART00000170560
annexin A1b
chr5_+_25585869 0.36 ENSDART00000138060
si:dkey-229d2.7
chr16_-_29387215 0.36 ENSDART00000148787
S100 calcium binding protein A1
chr25_-_29415369 0.36 ENSDART00000110774
ENSDART00000019183
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr5_+_13870340 0.35 ENSDART00000160690
hexokinase 2
chr12_-_9132682 0.35 ENSDART00000066471
ADAM metallopeptidase domain 8b
chr18_-_5598958 0.35 ENSDART00000161538
cytochrome P450, family 1, subfamily A
chr25_-_16600811 0.35 ENSDART00000011397
carboxypeptidase A2 (pancreatic)
chr6_+_36381709 0.35 ENSDART00000004727
Rh family, C glycoprotein, like 1
chr18_+_8346920 0.35 ENSDART00000083421
carnitine palmitoyltransferase 1B (muscle)
chr5_+_57658898 0.35 ENSDART00000074268
ENSDART00000124568
zgc:153929
chr15_-_41689684 0.34 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr4_-_20181964 0.34 ENSDART00000022539
fibrinogen-like 2a
chr17_-_6198823 0.34 ENSDART00000028407
ENSDART00000193636
protein tyrosine kinase 2 beta, a
chr4_-_26108053 0.34 ENSDART00000066951
si:ch211-244b2.4
chr13_-_31008275 0.34 ENSDART00000139394
WDFY family member 4
chr14_+_11430796 0.34 ENSDART00000165275
si:ch211-153b23.3
chr6_+_6270686 0.34 ENSDART00000129530
ENSDART00000156859
ribosomal protein S27a
chr2_+_7192966 0.34 ENSDART00000142735
si:ch211-13f8.1
chr13_-_20540790 0.34 ENSDART00000131467
si:ch1073-126c3.2
chr5_-_55560937 0.34 ENSDART00000148436
guanine nucleotide binding protein (G protein), alpha 14
chr17_+_24615091 0.34 ENSDART00000064739
ribosomal protein L13a
chr12_-_25294769 0.34 ENSDART00000153306
hydroxycarboxylic acid receptor 1-4
chr14_+_21699414 0.34 ENSDART00000169942
syntaxin 3A
chr6_-_10752937 0.34 ENSDART00000135093
Obg-like ATPase 1
chr10_-_21941443 0.33 ENSDART00000174954

chr12_-_10365875 0.33 ENSDART00000142386
ENSDART00000007335
NDC80 kinetochore complex component
chr3_-_15734358 0.33 ENSDART00000137325
major vault protein
chr3_+_29640996 0.33 ENSDART00000011052
eukaryotic translation initiation factor 3, subunit D
chr2_+_24762567 0.33 ENSDART00000078866
interferon, gamma-inducible protein 30
chr21_-_22715297 0.33 ENSDART00000065548
complement component 1, q subcomponent, B chain
chr25_+_34845469 0.33 ENSDART00000145416
transmembrane protein 231
chr22_-_24297510 0.33 ENSDART00000163297
si:ch211-117l17.6
chr14_-_38929885 0.32 ENSDART00000148737
Bruton agammaglobulinemia tyrosine kinase
chr18_-_16922905 0.32 ENSDART00000187165
WEE1 G2 checkpoint kinase
chr22_-_10110959 0.32 ENSDART00000031005
ENSDART00000147580
glutaminase 2b (liver, mitochondrial)
chr25_+_3104959 0.32 ENSDART00000167130
RAB3A interacting protein (rabin3)-like 1
chr3_-_32071468 0.32 ENSDART00000121979

chr20_-_33675676 0.32 ENSDART00000147168
rho-associated, coiled-coil containing protein kinase 2b
chr18_+_7553950 0.32 ENSDART00000193420
ENSDART00000062143
zgc:77650
chr11_-_10659195 0.32 ENSDART00000115255
MCF.2 cell line derived transforming sequence-like 2
chr9_+_13682133 0.32 ENSDART00000175639
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr19_+_14113886 0.32 ENSDART00000169343
keratinocyte differentiation factor 1b
chr5_-_30615901 0.32 ENSDART00000147769
si:ch211-117m20.5
chr24_-_4765740 0.32 ENSDART00000121576
carboxypeptidase B1 (tissue)
chr2_+_10134345 0.32 ENSDART00000100725
alpha-2-HS-glycoprotein 2
chr9_-_44953349 0.32 ENSDART00000135156
villin 1
chr8_+_52442622 0.32 ENSDART00000012758
zgc:77112
chr24_-_2843107 0.32 ENSDART00000165290
cytochrome b5 type A (microsomal)
chr25_+_35020529 0.31 ENSDART00000158016
filamin C, gamma a (actin binding protein 280)
chr5_+_2815021 0.31 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr14_+_10505464 0.31 ENSDART00000091224
P2Y receptor family member 10
chr25_+_35051656 0.31 ENSDART00000133379
histone cluster 2, H3c
chr1_-_59139848 0.31 ENSDART00000191863
si:ch1073-110a20.2
chr8_+_999421 0.31 ENSDART00000149528
fatty acid binding protein 1b, tandem duplicate 1
chr13_+_18533005 0.31 ENSDART00000136024
finTRIM family, member 14-like
chr16_+_23984179 0.31 ENSDART00000175879
apolipoprotein C-II
chr20_-_38746889 0.31 ENSDART00000140275
tripartite motif containing 54
chr17_+_27456804 0.31 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr6_-_27891961 0.31 ENSDART00000155116
im:7152348
chr24_-_26854032 0.31 ENSDART00000087991
fibronectin type III domain containing 3Bb
chr24_-_26328721 0.31 ENSDART00000125468
apolipoprotein Db
chr10_-_41352502 0.31 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr7_+_48761646 0.31 ENSDART00000017467
aggrecan a
chr24_+_26329018 0.31 ENSDART00000145752
myoneurin
chr5_-_68244564 0.31 ENSDART00000169350

chr17_+_53418445 0.30 ENSDART00000097631
solute carrier family 9 member A1b
chr3_+_1211242 0.30 ENSDART00000171287
ENSDART00000165769
polymerase (DNA-directed), delta interacting protein 3
chr16_-_19568388 0.30 ENSDART00000141616
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr19_-_40175800 0.30 ENSDART00000102904
immune-related, lectin-like receptor 4
chr6_-_15641686 0.30 ENSDART00000135583
melanophilin a
chr7_+_56577906 0.30 ENSDART00000184023
haptoglobin
chr5_+_37091626 0.30 ENSDART00000161054
transgelin 2
chr13_+_46941930 0.30 ENSDART00000056962
F-box protein 5
chr16_+_16826504 0.30 ENSDART00000108691
potassium inwardly-rectifying channel, subfamily J, member 14
chr20_-_33556983 0.30 ENSDART00000168798
rho-associated, coiled-coil containing protein kinase 2b, like
chr7_+_73670137 0.29 ENSDART00000050357
bloodthirsty-related gene family, member 12
chr23_+_19814371 0.29 ENSDART00000182897
emerin (Emery-Dreifuss muscular dystrophy)
chr4_-_17812131 0.29 ENSDART00000025731
Spi-C transcription factor (Spi-1/PU.1 related)
chr11_-_40147032 0.29 ENSDART00000052918
si:dkey-264d12.4
chr7_+_38380135 0.29 ENSDART00000174005
rhophilin, Rho GTPase binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of nfil3-4+si:dkey-172o19.2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 0.6 GO:0055026 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.2 1.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.5 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 0.5 GO:0002631 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.6 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 0.4 GO:0003156 regulation of organ formation(GO:0003156)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 0.4 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.7 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.0 GO:2000108 positive regulation of leukocyte apoptotic process(GO:2000108)
0.1 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.7 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 0.3 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.1 0.4 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.6 GO:0031284 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.6 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 0.4 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.3 GO:0006565 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.1 0.9 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.4 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.6 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 0.2 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.3 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.3 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.4 GO:0051883 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.1 0.3 GO:0051503 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.3 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.2 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.2 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 0.3 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.2 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.2 GO:0034397 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.2 GO:0097435 fibril organization(GO:0097435)
0.1 0.2 GO:0060467 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.1 0.5 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.2 GO:0003418 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.2 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.0 0.2 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.8 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 0.4 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.0 0.4 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0009110 vitamin biosynthetic process(GO:0009110) fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.2 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0099625 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.4 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)
0.0 1.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0070285 pigment cell development(GO:0070285)
0.0 0.1 GO:2000793 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.2 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.2 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.0 0.8 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.5 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.2 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.0 0.2 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.3 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 1.5 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.4 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 1.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:0009749 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.1 GO:0032812 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.2 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.0 0.6 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.3 GO:0010885 regulation of cholesterol storage(GO:0010885)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.5 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.4 GO:0016203 muscle attachment(GO:0016203)
0.0 0.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0042493 response to drug(GO:0042493)
0.0 1.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 0.3 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.6 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.3 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cyclic nucleotide metabolic process(GO:0030801) positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of cyclase activity(GO:0031281) positive regulation of adenylate cyclase activity(GO:0045762) positive regulation of lyase activity(GO:0051349) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.0 0.2 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.4 GO:0030168 platelet activation(GO:0030168)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.6 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790) regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.0 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.3 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.3 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.1 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.1 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.0 0.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0008210 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.0 0.0 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.5 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.5 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0030730 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 0.1 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.2 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.1 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.1 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.1 GO:0021885 forebrain cell migration(GO:0021885)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0043255 regulation of polysaccharide metabolic process(GO:0032881) regulation of polysaccharide biosynthetic process(GO:0032885) regulation of carbohydrate biosynthetic process(GO:0043255)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.5 GO:0007596 blood coagulation(GO:0007596)
0.0 0.3 GO:0007568 aging(GO:0007568)
0.0 0.2 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.1 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0051180 vitamin transport(GO:0051180)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.6 GO:0032433 filopodium tip(GO:0032433)
0.1 0.4 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 1.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.5 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.2 GO:0098536 deuterosome(GO:0098536)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.1 0.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.2 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.1 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.5 GO:0000796 condensin complex(GO:0000796)
0.1 0.4 GO:0016234 inclusion body(GO:0016234)
0.1 0.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.2 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.6 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.7 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:1990077 primosome complex(GO:1990077)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.2 GO:0030428 cell septum(GO:0030428)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0097268 cytoophidium(GO:0097268)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0005880 nuclear microtubule(GO:0005880)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 1.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.9 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0034518 RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.2 0.7 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.2 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 0.4 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.1 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 0.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.2 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.1 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.3 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.2 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.1 0.3 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.2 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.2 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.6 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 1.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.4 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.4 GO:0070330 aromatase activity(GO:0070330)
0.1 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.2 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.3 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.2 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.0 0.3 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 1.0 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.3 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.5 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.3 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.3 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 0.2 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0004100 chitin synthase activity(GO:0004100)
0.0 1.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 1.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 0.3 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.4 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 3.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 1.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.3 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling