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PRJNA207719: Tissue specific transcriptome profiling
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Results for pax1a+pax1b_pax9
Z-value: 1.14
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Transcription factors associated with pax1a+pax1b_pax9
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
pax1a
|
ENSDARG00000008203 | paired box 1a |
|
pax1b
|
ENSDARG00000073814 | paired box 1b |
|
pax9
|
ENSDARG00000053829 | paired box 9 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pax1b | dr11_v1_chr20_-_48701593_48701593 | -0.74 | 1.6e-01 | Click! |
| pax1a | dr11_v1_chr17_+_42274240_42274240 | -0.53 | 3.6e-01 | Click! |
| pax9 | dr11_v1_chr17_-_38291065_38291065 | -0.53 | 3.6e-01 | Click! |
Activity profile of pax1a+pax1b_pax9 motif
Sorted Z-values of pax1a+pax1b_pax9 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_44282796 | 3.71 |
ENSDART00000163040
ENSDART00000166923 ENSDART00000056372 ENSDART00000109251 ENSDART00000132682 |
mpz
|
myelin protein zero |
| chr2_-_44283554 | 3.60 |
ENSDART00000184684
|
mpz
|
myelin protein zero |
| chr21_+_13861589 | 2.77 |
ENSDART00000015629
ENSDART00000171306 |
stxbp1a
|
syntaxin binding protein 1a |
| chr12_-_18483348 | 1.32 |
ENSDART00000152757
|
tex2l
|
testis expressed 2, like |
| chr25_+_6306885 | 0.92 |
ENSDART00000142705
ENSDART00000067510 |
crabp1a
|
cellular retinoic acid binding protein 1a |
| chr15_+_41836104 | 0.82 |
ENSDART00000137434
|
pxylp1
|
2-phosphoxylose phosphatase 1 |
| chr24_+_41690545 | 0.81 |
ENSDART00000160069
|
lama1
|
laminin, alpha 1 |
| chr9_+_34334156 | 0.56 |
ENSDART00000144272
|
pou2f1b
|
POU class 2 homeobox 1b |
| chr8_+_48966165 | 0.56 |
ENSDART00000165425
|
aak1a
|
AP2 associated kinase 1a |
| chr1_+_39553040 | 0.54 |
ENSDART00000137676
|
tenm3
|
teneurin transmembrane protein 3 |
| chr5_-_29643381 | 0.52 |
ENSDART00000034849
|
grin1b
|
glutamate receptor, ionotropic, N-methyl D-aspartate 1b |
| chr20_+_29587995 | 0.47 |
ENSDART00000153339
|
adam17b
|
ADAM metallopeptidase domain 17b |
| chr5_-_201600 | 0.43 |
ENSDART00000158495
|
CABZ01088906.1
|
|
| chr12_-_7854216 | 0.42 |
ENSDART00000149594
|
ank3b
|
ankyrin 3b |
| chr4_-_8902406 | 0.39 |
ENSDART00000192962
|
mpped1
|
metallophosphoesterase domain containing 1 |
| chr20_+_12702923 | 0.38 |
ENSDART00000163499
|
zgc:153383
|
zgc:153383 |
| chr1_-_51261420 | 0.38 |
ENSDART00000168685
|
kif16ba
|
kinesin family member 16Ba |
| chr3_-_50277959 | 0.32 |
ENSDART00000082773
ENSDART00000139524 |
arl16
|
ADP-ribosylation factor-like 16 |
| chr1_-_46343999 | 0.29 |
ENSDART00000145117
ENSDART00000193233 |
atp11a
|
ATPase phospholipid transporting 11A |
| chr9_-_13871935 | 0.28 |
ENSDART00000146597
|
raph1a
|
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a |
| chr16_+_20738740 | 0.27 |
ENSDART00000079343
|
jazf1b
|
JAZF zinc finger 1b |
| chr10_-_39154778 | 0.26 |
ENSDART00000186811
|
slc37a4b
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4b |
| chr2_+_394166 | 0.21 |
ENSDART00000155733
|
mylk4a
|
myosin light chain kinase family, member 4a |
| chr11_+_24804556 | 0.21 |
ENSDART00000082761
ENSDART00000186283 |
adipor1a
|
adiponectin receptor 1a |
| chr17_+_956821 | 0.21 |
ENSDART00000082101
|
ppp2r5ca
|
protein phosphatase 2, regulatory subunit B', gamma a |
| chr5_+_52844681 | 0.20 |
ENSDART00000162459
ENSDART00000184914 |
scarb2a
|
scavenger receptor class B, member 2a |
| chr6_-_41079209 | 0.20 |
ENSDART00000151592
|
rab44
|
RAB44, member RAS oncogene family |
| chr17_+_996509 | 0.19 |
ENSDART00000158830
|
cyp1c2
|
cytochrome P450, family 1, subfamily C, polypeptide 2 |
| chr24_+_3478871 | 0.16 |
ENSDART00000111491
ENSDART00000134598 ENSDART00000142407 |
wdr37
|
WD repeat domain 37 |
| chr9_+_38074082 | 0.16 |
ENSDART00000017833
|
cacnb4a
|
calcium channel, voltage-dependent, beta 4a subunit |
| chr13_-_24379271 | 0.15 |
ENSDART00000046360
|
rhoua
|
ras homolog family member Ua |
| chr11_+_37278457 | 0.12 |
ENSDART00000188946
|
creld1a
|
cysteine-rich with EGF-like domains 1a |
| chr20_-_31075972 | 0.12 |
ENSDART00000122927
|
si:ch211-198b3.4
|
si:ch211-198b3.4 |
| chr11_-_4023940 | 0.10 |
ENSDART00000058728
ENSDART00000171245 |
nek4
|
NIMA-related kinase 4 |
| chr23_+_9522781 | 0.10 |
ENSDART00000136486
|
osbpl2b
|
oxysterol binding protein-like 2b |
| chr3_+_47322494 | 0.06 |
ENSDART00000102202
|
ppap2d
|
phosphatidic acid phosphatase type 2D |
| chr10_-_39154594 | 0.05 |
ENSDART00000148825
|
slc37a4b
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4b |
| chr6_-_31224563 | 0.03 |
ENSDART00000104616
|
lepr
|
leptin receptor |
Network of associatons between targets according to the STRING database.
First level regulatory network of pax1a+pax1b_pax9
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.9 | GO:0016103 | diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653) |
| 0.2 | 0.8 | GO:0042762 | regulation of sulfur metabolic process(GO:0042762) |
| 0.1 | 0.5 | GO:1903385 | dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385) |
| 0.1 | 0.8 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.1 | 3.0 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.5 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.5 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.0 | 0.2 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.0 | 0.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 0.1 | GO:0032488 | Cdc42 protein signal transduction(GO:0032488) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 7.3 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.5 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 3.0 | GO:0030141 | secretory granule(GO:0030141) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 2.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 0.2 | GO:0050649 | testosterone 6-beta-hydroxylase activity(GO:0050649) |
| 0.0 | 0.5 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.0 | 0.5 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.2 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.0 | 0.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.2 | GO:0072542 | phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |