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PRJNA207719: Tissue specific transcriptome profiling

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Results for phox2ba

Z-value: 0.43

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Transcription factors associated with phox2ba

Gene Symbol Gene ID Gene Info
phox2ba
ENSDARG00000075330 paired like homeobox 2Ba

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
phox2badr11_v1_chr1_-_19079957_190799570.345.8e-01Click!

Activity profile of phox2ba motif

Sorted Z-values of phox2ba motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_77551860 0.54 ENSDART00000188176
AL935186.6

chr2_-_53481912 0.49 ENSDART00000189610
hsd11b1lb
hydroxysteroid (11-beta) dehydrogenase 1-like b
chr24_-_27436319 0.43 ENSDART00000171489
si:dkey-25o1.7
si:dkey-25o1.7
chr9_-_54304684 0.43 ENSDART00000109512
il13
interleukin 13
chr4_-_4834347 0.28 ENSDART00000141803
coa6
cytochrome c oxidase assembly factor 6
chr3_+_6469754 0.25 ENSDART00000185809
NUP85 (1 of many)
nucleoporin 85
chr14_+_45702521 0.24 ENSDART00000112470
ccdc88b
coiled-coil domain containing 88B
chr4_-_4834617 0.23 ENSDART00000141539
coa6
cytochrome c oxidase assembly factor 6
chr15_+_5360407 0.21 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr13_-_12021566 0.19 ENSDART00000125430
pprc1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr1_+_58205904 0.19 ENSDART00000147324
si:dkey-222h21.12
si:dkey-222h21.12
chr13_-_42560662 0.19 ENSDART00000124898
CR792417.1

chr8_-_36370552 0.18 ENSDART00000097932
ENSDART00000148323
si:busm1-104n07.3
si:busm1-104n07.3
chr12_-_30043809 0.18 ENSDART00000150220
ENSDART00000075889
ENSDART00000148847
trub1
TruB pseudouridine (psi) synthase family member 1
chr17_+_45395846 0.18 ENSDART00000058793
nenf
neudesin neurotrophic factor
chr13_-_34862452 0.17 ENSDART00000134573
ENSDART00000047552
sptlc3
serine palmitoyltransferase, long chain base subunit 3
chr1_+_57774454 0.17 ENSDART00000152507
si:dkey-1c7.2
si:dkey-1c7.2
chr24_-_26484298 0.17 ENSDART00000140647
eif5a
eukaryotic translation initiation factor 5A
chr14_-_45702721 0.17 ENSDART00000165727
si:dkey-226n24.1
si:dkey-226n24.1
chr18_+_27000850 0.16 ENSDART00000188906
ENSDART00000086131
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr1_+_26677406 0.16 ENSDART00000183427
ENSDART00000180366
ENSDART00000181997
si:dkey-25o16.4
si:dkey-25o16.4
chr10_+_26646104 0.16 ENSDART00000187685
adgrg4b
adhesion G protein-coupled receptor G4b
chr18_+_27001115 0.16 ENSDART00000133547
pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr2_+_44512324 0.15 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
pask
PAS domain containing serine/threonine kinase
chr10_+_26645953 0.15 ENSDART00000131482
adgrg4b
adhesion G protein-coupled receptor G4b
chr1_+_33390286 0.14 ENSDART00000139004
dhrsx
dehydrogenase/reductase (SDR family) X-linked
chr19_+_4800068 0.14 ENSDART00000020686
st3gal1l
ST3 beta-galactoside alpha-2,3-sialyltransferase 1, like
chr22_-_15671525 0.14 ENSDART00000080286
si:ch1073-396h14.1
si:ch1073-396h14.1
chr1_+_26676758 0.13 ENSDART00000152299
si:dkey-25o16.4
si:dkey-25o16.4
chr9_-_21067971 0.13 ENSDART00000004333
tbx15
T-box 15
chr11_+_13223625 0.13 ENSDART00000161275
abcb11b
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr2_-_51223658 0.12 ENSDART00000171770
pigrl4.2
polymeric immunoglobulin receptor-like 4.2
chr7_+_8543317 0.12 ENSDART00000114998
jac8
jacalin 8
chr18_+_27598755 0.12 ENSDART00000193808
cd82b
CD82 molecule b
chr1_-_33380011 0.11 ENSDART00000141347
ENSDART00000136383
cd99
CD99 molecule
chr2_+_55982940 0.10 ENSDART00000097753
ENSDART00000097751
nmrk2
nicotinamide riboside kinase 2
chr5_-_44286987 0.10 ENSDART00000184112
si:ch73-337l15.2
si:ch73-337l15.2
chr19_-_32600138 0.10 ENSDART00000052101
zgc:91944
zgc:91944
chr4_+_76509294 0.10 ENSDART00000099899
ms4a17a.17
membrane-spanning 4-domains, subfamily A, member 17A.17
chr16_+_7662609 0.10 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
bves
blood vessel epicardial substance
chr6_-_16493516 0.09 ENSDART00000022499
psmb3
proteasome subunit beta 3
chr14_+_32839535 0.09 ENSDART00000168975
arr3b
arrestin 3b, retinal (X-arrestin)
chr8_-_38355268 0.09 ENSDART00000129597
sorbs3
sorbin and SH3 domain containing 3
chr6_+_11850359 0.08 ENSDART00000109552
ENSDART00000188139
ENSDART00000181499
ENSDART00000178269
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr22_+_2533514 0.08 ENSDART00000147967
si:ch73-92e7.4
si:ch73-92e7.4
chr21_+_27189490 0.08 ENSDART00000125349
bada
BCL2 associated agonist of cell death a
chr20_-_38801981 0.08 ENSDART00000125333
cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr24_+_19542323 0.08 ENSDART00000140379
ENSDART00000142830
sulf1
sulfatase 1
chr2_-_38282079 0.08 ENSDART00000145808
rnf212b
si:ch211-10e2.1
chr16_+_1471 0.08 ENSDART00000181972
CABZ01090785.1

chr8_+_7854130 0.08 ENSDART00000165575
cxxc1a
CXXC finger protein 1a
chr15_-_35960250 0.08 ENSDART00000186765
col4a4
collagen, type IV, alpha 4
chr23_+_30048849 0.07 ENSDART00000126027
uts2a
urotensin 2, alpha
chr17_+_30587333 0.07 ENSDART00000156500
nhsl1a
NHS-like 1a
chr11_-_23459779 0.07 ENSDART00000183935
ENSDART00000184125
ENSDART00000193284
plekha6
pleckstrin homology domain containing, family A member 6
chr14_+_18781082 0.07 ENSDART00000108793
si:ch211-111e20.1
si:ch211-111e20.1
chr1_+_10074343 0.07 ENSDART00000190194
si:ch73-132f6.5
si:ch73-132f6.5
chr6_+_16493755 0.07 ENSDART00000126318
si:ch73-193c12.2
si:ch73-193c12.2
chr13_+_47623916 0.06 ENSDART00000109266
mertka
c-mer proto-oncogene tyrosine kinase a
chr13_+_42858228 0.06 ENSDART00000179763
cdh23
cadherin-related 23
chr2_-_26590628 0.06 ENSDART00000025120
ndc1
NDC1 transmembrane nucleoporin
chr5_-_44286778 0.06 ENSDART00000146080
si:ch73-337l15.2
si:ch73-337l15.2
chr1_+_10074601 0.05 ENSDART00000168473
si:ch73-132f6.5
si:ch73-132f6.5
chr19_-_32600638 0.05 ENSDART00000143497
zgc:91944
zgc:91944
chr17_+_24821627 0.05 ENSDART00000112389
wdr43
WD repeat domain 43
chr5_-_38161033 0.05 ENSDART00000145907
gucy2d
guanylate cyclase 2D, retinal
chr21_+_18910502 0.04 ENSDART00000147567
smpd4
sphingomyelin phosphodiesterase 4
chr23_-_14830627 0.04 ENSDART00000134659
sla2
Src-like-adaptor 2
chr19_-_10373630 0.04 ENSDART00000131517
si:ch211-232m10.6
si:ch211-232m10.6
chr17_+_21919131 0.03 ENSDART00000048136
htra1a
HtrA serine peptidase 1a
chr5_-_44829719 0.03 ENSDART00000019104
fbp2
fructose-1,6-bisphosphatase 2
chr7_-_20796935 0.03 ENSDART00000162357
dnajc3b
DnaJ (Hsp40) homolog, subfamily C, member 3b
chr8_+_10862353 0.03 ENSDART00000140717
brpf3b
bromodomain and PHD finger containing, 3b
chr14_+_31493306 0.02 ENSDART00000138341
phf6
PHD finger protein 6
chr6_-_11800427 0.02 ENSDART00000126243
march7
membrane-associated ring finger (C3HC4) 7
chr21_+_40239192 0.02 ENSDART00000135857
or115-9
odorant receptor, family F, subfamily 115, member 9
chr2_-_9971609 0.01 ENSDART00000137924
ENSDART00000048655
ENSDART00000131613
zgc:55943
zgc:55943
chr23_+_37090889 0.01 ENSDART00000074406
ubxn10
UBX domain protein 10
chr6_-_9630081 0.01 ENSDART00000013066
ercc3
excision repair cross-complementation group 3
chr15_+_36310442 0.01 ENSDART00000154678
gmnc
geminin coiled-coil domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of phox2ba

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0 0.1 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.0 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.0 0.4 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane