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PRJNA207719: Tissue specific transcriptome profiling

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Results for pou2f2a

Z-value: 1.07

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Transcription factors associated with pou2f2a

Gene Symbol Gene ID Gene Info
ENSDARG00000019658 POU class 2 homeobox 2a
ENSDARG00000036816 POU class 2 homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f2adr11_v1_chr16_+_10918252_10918252-0.523.7e-01Click!

Activity profile of pou2f2a motif

Sorted Z-values of pou2f2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_2669405 1.75 ENSDART00000110202
chemokine (C-C motif) ligand 27b
chr5_-_63302944 0.90 ENSDART00000047110
gelsolin b
chr19_-_340641 0.87 ENSDART00000183848
golgi phosphoprotein 3-like
chr17_+_26965351 0.85 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr19_-_40198478 0.82 ENSDART00000191736
granulin 2
chr1_-_59169815 0.78 ENSDART00000100163
wu:fk65c09
chr16_-_24550029 0.75 ENSDART00000108590
si:ch211-79k12.1
chr16_+_17714664 0.75 ENSDART00000149042
si:dkey-87o1.2
chr17_-_25382367 0.72 ENSDART00000162306
ENSDART00000165282
LCK proto-oncogene, Src family tyrosine kinase
chr22_+_980290 0.66 ENSDART00000065377
differentially expressed in FDCP 6b homolog (mouse)
chr17_-_2039511 0.66 ENSDART00000160223
serine peptidase inhibitor, Kunitz type 1 a
chr16_+_17715243 0.65 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
chr8_+_20393250 0.65 ENSDART00000015038
zeta chain of T cell receptor associated protein kinase 70
chr23_+_7692042 0.62 ENSDART00000018512
protein O-fucosyltransferase 1
chr5_+_58550291 0.61 ENSDART00000184983
ENSDART00000044803
POU class 2 homeobox 3
chr23_+_23232136 0.61 ENSDART00000126479
ENSDART00000187764
pleckstrin homology domain containing, family N member 1
chr5_+_26212621 0.58 ENSDART00000134432
occludin b
chr14_-_15171435 0.58 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
chr5_+_15202495 0.56 ENSDART00000144915
T-box 1
chr4_-_4612116 0.56 ENSDART00000130601
Danio rerio apoptosis facilitator Bcl-2-like protein 14 (LOC101885512), mRNA.
chr5_-_42272517 0.55 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
chr7_-_57637779 0.52 ENSDART00000028017
MAD2 mitotic arrest deficient-like 1 (yeast)
chr19_+_19988869 0.51 ENSDART00000151024
oxysterol binding protein-like 3a
chr23_-_31372639 0.51 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
high mobility group nucleosomal binding domain 3
chr14_-_38929885 0.50 ENSDART00000148737
Bruton agammaglobulinemia tyrosine kinase
chr7_-_21924372 0.50 ENSDART00000113652
si:dkey-85k7.10
chr5_+_15203421 0.50 ENSDART00000040826
T-box 1
chr24_-_31904924 0.49 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr7_+_15736230 0.48 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr1_-_55118745 0.47 ENSDART00000133915
SERTA domain containing 2a
chr14_-_8080416 0.47 ENSDART00000045109
zgc:92242
chr24_-_23758003 0.47 ENSDART00000178085
Danio rerio minichromosome maintenance domain containing 2 (mcmdc2), mRNA.
chr14_+_36889893 0.47 ENSDART00000124159
si:ch211-132p1.3
chr9_-_34396264 0.46 ENSDART00000045754
growth hormone regulated TBC protein 1b
chr14_+_35428152 0.46 ENSDART00000172597
synaptotagmin-like 4
chr7_+_66565572 0.46 ENSDART00000180250
transmembrane protein 176l.3b
chr25_+_22320738 0.45 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr21_-_17290941 0.45 ENSDART00000147993
growth factor independent 1B transcription repressor
chr14_-_46198373 0.43 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr3_-_27646070 0.42 ENSDART00000122031
ENSDART00000151027
si:ch211-157c3.4
chr3_+_49021079 0.42 ENSDART00000162012
zgc:163083
chr18_-_42830563 0.42 ENSDART00000191488
tetratricopeptide repeat domain 36
chr24_-_32452355 0.42 ENSDART00000146511
coiled-coil domain containing 129
chr18_+_30567945 0.42 ENSDART00000078894
interferon regulatory factor 8
chr6_+_56147812 0.41 ENSDART00000150219
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr4_+_2230701 0.41 ENSDART00000080439
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr23_-_1017605 0.41 ENSDART00000138290
cadherin 26, tandem duplicate 1
chr7_-_8315179 0.39 ENSDART00000184049
coagulation factor XIII, A1 polypeptide b
chr3_-_32337653 0.39 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr5_-_34993242 0.39 ENSDART00000134516
ENSDART00000051295
basic transcription factor 3
chr11_-_11575070 0.39 ENSDART00000142208
zgc:110712
chr23_-_1017428 0.39 ENSDART00000110588
ENSDART00000183158
cadherin 26, tandem duplicate 1
chr14_-_4145594 0.39 ENSDART00000077348
caspase 3, apoptosis-related cysteine peptidase b
chr5_-_33287691 0.38 ENSDART00000004238
ribosomal protein L7a
chr18_-_3520358 0.38 ENSDART00000181412
calpain 5a
chr19_+_7864767 0.38 ENSDART00000137540
ENSDART00000151642
si:dkeyp-85e10.3
chr9_+_33423170 0.38 ENSDART00000141542
si:dkey-216e24.9
chr3_-_3209432 0.38 ENSDART00000140635
si:ch211-229i14.2
chr16_+_20895904 0.37 ENSDART00000052662
homeobox A13b
chr4_-_9780931 0.37 ENSDART00000134280
ENSDART00000150664
ENSDART00000150304
ENSDART00000080744
SVOP-like
chr17_-_24916889 0.37 ENSDART00000156157
si:ch211-195o20.7
chr14_-_40821411 0.36 ENSDART00000166621
E74-like ETS transcription factor 1
chr3_+_29476085 0.35 ENSDART00000184495
ENSDART00000181058
family with sequence similarity 83, member Fa
chr9_-_56272465 0.34 ENSDART00000039235
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_6553460 0.34 ENSDART00000172903
si:ch1073-220m6.1
chr21_-_34926619 0.34 ENSDART00000065337
ENSDART00000192740
kinesin family member 20A
chr7_+_4795707 0.33 ENSDART00000142704
si:dkey-28d5.4
chr17_-_26867725 0.33 ENSDART00000153590
si:dkey-221l4.10
chr7_-_3649414 0.33 ENSDART00000064279
si:ch211-282j17.2
chr21_+_31253048 0.32 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
argininosuccinate lyase
chr5_+_54400971 0.32 ENSDART00000169695
B-box and SPRY domain containing
chr24_+_39990695 0.31 ENSDART00000040281

chr5_+_26204561 0.30 ENSDART00000137178
MARVEL domain containing 2b
chr13_-_25305179 0.30 ENSDART00000110064
plasminogen activator, urokinase a
chr9_+_54178475 0.30 ENSDART00000104475
thymosin, beta 4 x
chr23_-_32092443 0.30 ENSDART00000133688
LETM1 domain containing 1
chr12_-_4176329 0.29 ENSDART00000092746
si:dkey-32n7.7
chr1_-_51720633 0.29 ENSDART00000045894
ribonuclease H2, subunit A
chr25_-_36248053 0.29 ENSDART00000134928
nuclear factor of activated T cells 3b
chr5_-_23749348 0.29 ENSDART00000140766
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2
chr20_-_25626693 0.29 ENSDART00000132247
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr3_-_34060153 0.29 ENSDART00000151610
immunoglobulin heavy variable 1-1
chr2_-_6482240 0.29 ENSDART00000132623
regulator of G protein signaling 13
chr19_+_19775757 0.28 ENSDART00000164677
homeobox A3a
chr12_-_2940070 0.28 ENSDART00000112182
family with sequence similarity 20, member A
chr8_+_7315625 0.28 ENSDART00000135655
ENSDART00000181048
selenoprotein H
chr17_-_26868169 0.28 ENSDART00000157204
si:dkey-221l4.10
chr4_+_11464255 0.28 ENSDART00000008584
GDP dissociation inhibitor 2
chr7_+_4931366 0.28 ENSDART00000172384
ENSDART00000138168
ENSDART00000114543
si:dkey-83f18.3
chr1_+_26667872 0.28 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemogen
chr17_+_6563307 0.27 ENSDART00000156454
adhesion G protein-coupled receptor F3a
chr7_+_4987530 0.27 ENSDART00000132983
ENSDART00000137067
si:dkey-81n2.1
chr7_+_3442834 0.27 ENSDART00000138247
si:ch211-285c6.2
chr20_+_25626479 0.27 ENSDART00000143883
phosphoribosyl pyrophosphate amidotransferase
chr10_+_10351685 0.27 ENSDART00000109432
cerebral endothelial cell adhesion molecule
chr7_-_32020858 0.27 ENSDART00000023568
kinesin family member 18A
chr7_+_36041509 0.27 ENSDART00000162850
iroquois homeobox 3a
chr18_+_13248956 0.26 ENSDART00000080709
phospholipase C, gamma 2
chr6_+_28428329 0.26 ENSDART00000188056
LIM domain containing preferred translocation partner in lipoma
chr17_-_27382826 0.26 ENSDART00000186657
ENSDART00000155986
ENSDART00000191060
ENSDART00000077608
si:ch1073-358c10.1
chr7_+_4922104 0.26 ENSDART00000135154
si:dkey-28d5.11
chr13_-_40411908 0.26 ENSDART00000057094
ENSDART00000150091
NK2 homeobox 3
chr7_+_4624926 0.25 ENSDART00000137387
si:dkey-83f18.6
chr10_-_1276046 0.25 ENSDART00000169779
PDZ and LIM domain 5b
chr13_-_30996072 0.25 ENSDART00000181661
WDFY family member 4
chr14_+_46020571 0.25 ENSDART00000157617
ENSDART00000083928
C1q and TNF related 2
chr5_+_9259971 0.25 ENSDART00000163060
sushi domain containing 1
chr7_+_5007310 0.25 ENSDART00000146083
si:ch211-272h9.3
chr16_-_25608453 0.25 ENSDART00000140140
zgc:110410
chr16_+_19637384 0.25 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr15_-_4580763 0.24 ENSDART00000008170
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr16_+_52999778 0.24 ENSDART00000011506
naked cuticle homolog 2a
chr3_+_37112693 0.24 ENSDART00000055228
ENSDART00000144278
ENSDART00000138079
PSMC3 interacting protein
chr3_-_34113838 0.24 ENSDART00000151216
immunoglobulin heavy variable 4-2
chr14_-_32965169 0.24 ENSDART00000114973
caudal type homeobox 4
chr16_-_2870522 0.24 ENSDART00000148543
CUB domain containing protein 1a
chr2_+_10280645 0.24 ENSDART00000063996
growth arrest and DNA-damage-inducible, alpha, a
chr6_+_43450221 0.24 ENSDART00000075521
zgc:113054
chr14_+_35383267 0.24 ENSDART00000143818
clathrin interactor 1a
chr11_+_18612421 0.24 ENSDART00000110621
nuclear receptor coactivator 3
chr1_-_25177086 0.23 ENSDART00000144711
ENSDART00000177225
transmembrane protein 154
chr25_+_5288665 0.23 ENSDART00000169540

chr1_-_55166511 0.23 ENSDART00000150430
ENSDART00000035725
proliferation associated nuclear element
chr1_-_56208151 0.22 ENSDART00000183325
si:dkey-76b14.2
chr18_-_7481036 0.22 ENSDART00000101292
si:dkey-238c7.16
chr16_-_43065164 0.22 ENSDART00000149431
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Aa
chr6_+_19950107 0.22 ENSDART00000181632
phosphoinositide-3-kinase, regulatory subunit 5
chr1_-_51038885 0.22 ENSDART00000035150
spastin
chr7_+_44593756 0.22 ENSDART00000125365
si:ch211-189a15.5
chr3_+_28581397 0.22 ENSDART00000150893
septin 12
chr7_-_3792765 0.21 ENSDART00000060333
si:dkey-28d5.12
chr9_+_21820101 0.21 ENSDART00000145431
thioredoxin domain containing 9
chr7_-_3826639 0.21 ENSDART00000060330
si:dkey-88n24.10
chr12_+_37401331 0.21 ENSDART00000125040
si:ch211-152f22.4
chr8_-_19279784 0.21 ENSDART00000185892
zgc:77486
chr7_-_3792972 0.21 ENSDART00000146304
si:dkey-28d5.12
chr8_+_20994433 0.20 ENSDART00000141736
si:dkeyp-82a1.8
chr25_-_16057539 0.20 ENSDART00000090388
cytochrome b5 reductase 2
chr12_+_4900981 0.20 ENSDART00000171507
CD79b molecule, immunoglobulin-associated beta
chr3_+_41558682 0.20 ENSDART00000157023
caspase recruitment domain family, member 11
chr3_-_34054081 0.20 ENSDART00000151590
immunoglobulin heavy variable 1-2
chr7_-_3723144 0.20 ENSDART00000138945
si:ch211-282j17.8
chr21_-_11646878 0.20 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
calpastatin
chr7_+_4682458 0.20 ENSDART00000139271
si:ch211-225k7.2
chr8_+_30747940 0.19 ENSDART00000098975
purinergic receptor P2X, ligand-gated ion channel, 4b
chr1_+_58137020 0.19 ENSDART00000180887
si:ch211-15j1.4
chr20_+_18994059 0.19 ENSDART00000152380
L-threonine dehydrogenase
chr15_-_25556074 0.19 ENSDART00000124677
matrix metallopeptidase 20a (enamelysin)
chr8_+_28629741 0.19 ENSDART00000163915
si:dkey-109a10.2
chr4_+_9592486 0.19 ENSDART00000080829
heat shock protein 14
chr9_-_40073255 0.19 ENSDART00000189139
si:zfos-1425h8.1
chr25_+_8407892 0.19 ENSDART00000153536
mucin 5.2
chr7_-_3630019 0.18 ENSDART00000138164
ENSDART00000064277
si:dkey-192d15.3
chr7_+_4911590 0.18 ENSDART00000038628
si:dkey-28d5.11
chr6_+_6779114 0.18 ENSDART00000163493
ENSDART00000143359
Sec23 homolog B, COPII coat complex component
chr7_-_3850090 0.18 ENSDART00000113403
ENSDART00000137683
ENSDART00000049926
si:dkey-28d5.12
si:dkey-88n24.7
chr13_+_45582391 0.18 ENSDART00000058093
low density lipoprotein receptor adaptor protein 1b
chr2_-_51259371 0.18 ENSDART00000158049
ENSDART00000164916
ENSDART00000157792
si:ch211-215e19.6
chr13_-_2112450 0.18 ENSDART00000189343
family with sequence similarity 83, member B
chr8_+_50190742 0.18 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr7_+_4219234 0.18 ENSDART00000187891
ENSDART00000173246
ENSDART00000172808
si:ch211-63p21.4
chr8_+_36570508 0.18 ENSDART00000145868
polymerase (DNA directed), delta 2, regulatory subunit
chr7_-_3884424 0.17 ENSDART00000145641
si:dkey-88n24.3
chr7_-_3836896 0.17 ENSDART00000136227
si:dkey-88n24.8
chr10_+_4987766 0.17 ENSDART00000121959
si:ch73-234b20.5
chr11_+_18612166 0.17 ENSDART00000162694
nuclear receptor coactivator 3
chr7_-_29533127 0.17 ENSDART00000057289
annexin A2b
chr18_+_30998472 0.17 ENSDART00000154993
ENSDART00000099333
CD151 antigen, like
chr19_-_41518922 0.17 ENSDART00000164483
ENSDART00000062080
chromatin accessibility complex 1
chr10_+_8690936 0.17 ENSDART00000144218
si:dkey-27b3.4
chr15_-_16012963 0.16 ENSDART00000144138
HNF1 homeobox Ba
chr20_-_25542183 0.16 ENSDART00000024350
cytochrome P450, family 2, subfamily AD, polypeptide 2
chr23_-_20126257 0.16 ENSDART00000005021
transketolase b
chr20_+_18993452 0.16 ENSDART00000025509
L-threonine dehydrogenase
chr23_+_11347313 0.16 ENSDART00000135406
cell adhesion molecule L1-like a
chr8_+_36570791 0.16 ENSDART00000145566
ENSDART00000180527
polymerase (DNA directed), delta 2, regulatory subunit
chr25_-_18739924 0.16 ENSDART00000156328
si:dkeyp-93a5.2
chr7_+_4865367 0.16 ENSDART00000139120
si:dkey-28d5.8
chr23_+_12455295 0.16 ENSDART00000143752
ENSDART00000135785
si:ch211-153a8.4
chr10_+_42169982 0.16 ENSDART00000190905

chr1_-_45320126 0.16 ENSDART00000133572
si:ch73-90k17.1
chr7_-_3849926 0.16 ENSDART00000143064
si:dkey-88n24.7
chr7_+_4854690 0.15 ENSDART00000131645
si:dkey-28d5.7
chr7_+_4694762 0.15 ENSDART00000132862
si:ch211-225k7.3
chr7_+_4592676 0.15 ENSDART00000141073
si:dkey-83f18.15
chr24_-_8730913 0.15 ENSDART00000187228
ENSDART00000082349
ENSDART00000186660
transcription factor AP-2 alpha
chr7_-_3762896 0.15 ENSDART00000136711
ENSDART00000137140
si:ch211-282j17.11
chr19_+_14573998 0.15 ENSDART00000022076
family with sequence similarity 46, member Bb
chr7_-_3836635 0.15 ENSDART00000104350
si:dkey-88n24.8
chr2_+_7851493 0.15 ENSDART00000176910
si:ch211-38m6.6
chr9_-_9980704 0.15 ENSDART00000130243
ENSDART00000193475
UDP glucuronosyltransferase 1 family a, b
chr17_+_15297398 0.14 ENSDART00000156574
si:ch211-270g19.5
chr7_+_4572727 0.14 ENSDART00000137830
si:dkey-83f18.7
chr5_-_57686487 0.14 ENSDART00000074264
cytokine receptor family member B12
chr5_+_25585869 0.14 ENSDART00000138060
si:dkey-229d2.7
chr10_+_16756546 0.14 ENSDART00000168624

chr6_+_52212927 0.14 ENSDART00000143458
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr3_-_34032019 0.14 ENSDART00000151779
immunoglobulin heavy variable 13-2
chr2_-_51303937 0.14 ENSDART00000164111
si:ch211-215e19.8
chr13_+_24396666 0.14 ENSDART00000139197
ENSDART00000101200
zgc:153169

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0003156 regulation of organ formation(GO:0003156)
0.2 1.0 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 0.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.4 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.6 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.7 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.5 GO:0071333 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.1 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0007440 pancreatic D cell differentiation(GO:0003311) foregut morphogenesis(GO:0007440)
0.0 0.4 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.6 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.6 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.3 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.4 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 0.2 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.4 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:0021767 mammillary body development(GO:0021767)
0.0 0.9 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0070254 mucus secretion(GO:0070254)
0.0 0.2 GO:0048566 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572) embryonic digestive tract development(GO:0048566)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.5 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:0044806 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0060061 developmental induction(GO:0031128) Spemann organizer formation(GO:0060061)
0.0 0.2 GO:0045682 regulation of epidermis development(GO:0045682)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0033198 response to ATP(GO:0033198)
0.0 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.3 GO:0003181 atrioventricular valve morphogenesis(GO:0003181) atrioventricular canal development(GO:0036302)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0090594 inflammatory response to wounding(GO:0090594)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0042026 protein refolding(GO:0042026)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0071623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.1 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.0 0.1 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.1 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.2 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0032432 actin filament bundle(GO:0032432)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1901612 cardiolipin binding(GO:1901612)
0.2 0.5 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.4 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.3 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.4 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.0 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.0 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade