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PRJNA207719: Tissue specific transcriptome profiling

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Results for pou3f1

Z-value: 0.97

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Transcription factors associated with pou3f1

Gene Symbol Gene ID Gene Info
ENSDARG00000009823 POU class 3 homeobox 1
ENSDARG00000112302 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou3f1dr11_v1_chr16_+_33593116_335931160.951.2e-02Click!

Activity profile of pou3f1 motif

Sorted Z-values of pou3f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_30563115 1.39 ENSDART00000028566
si:ch211-200p22.4
chr22_+_20195280 1.29 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
chr23_+_28731379 0.99 ENSDART00000047378
cortistatin
chr18_-_36135799 0.97 ENSDART00000059344
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr23_+_44307996 0.97 ENSDART00000042430
discs, large homolog 4b (Drosophila)
chr19_-_28367413 0.90 ENSDART00000079092
si:dkey-261i16.5
chr19_-_30562648 0.90 ENSDART00000171006
hippocalcin like 4
chr3_-_5964557 0.86 ENSDART00000184738

chr21_-_27185915 0.86 ENSDART00000135052
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr9_-_18877597 0.85 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr23_+_36771593 0.85 ENSDART00000078240
membrane-associated ring finger (C3HC4) 9
chr16_-_12173399 0.84 ENSDART00000142574
calsyntenin 3
chr7_+_40228422 0.83 ENSDART00000052222
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr6_-_13187168 0.81 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr16_-_12173554 0.80 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr12_+_48480632 0.76 ENSDART00000158157
Rho GTPase activating protein 44
chr16_-_43971258 0.75 ENSDART00000141941
zinc finger protein, FOG family member 2a
chr7_-_38633867 0.73 ENSDART00000137424
C1q and TNF related 4
chr22_+_5106751 0.73 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr21_+_41743493 0.72 ENSDART00000192669
protein phosphatase 2, regulatory subunit B, beta b
chr10_+_22003750 0.72 ENSDART00000109420
Kv channel interacting protein 1 b
chr2_-_34555945 0.72 ENSDART00000056671
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr3_-_6519691 0.71 ENSDART00000165273
ENSDART00000179882
ENSDART00000172292
si:ch73-157i16.3
chr17_-_15528597 0.69 ENSDART00000150232
FYN proto-oncogene, Src family tyrosine kinase a
chr3_+_33345348 0.69 ENSDART00000059262
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr16_+_45746549 0.66 ENSDART00000190403
progestin and adipoQ receptor family member VI
chr23_+_28582865 0.63 ENSDART00000020296
L1 cell adhesion molecule, paralog a
chr13_+_33117528 0.63 ENSDART00000085719
si:ch211-10a23.2
chr6_-_13188667 0.62 ENSDART00000191654
ADAM metallopeptidase domain 23a
chr5_-_24000211 0.62 ENSDART00000188865
MAP7 domain containing 2a
chr5_-_16996482 0.60 ENSDART00000144501
polypeptide N-acetylgalactosaminyltransferase 9
chr6_+_4539953 0.60 ENSDART00000025031
POU class 4 homeobox 1
chr22_-_38516922 0.58 ENSDART00000151257
ENSDART00000151785
kinesin light chain 4
chr2_+_24203229 0.57 ENSDART00000138088
microtubule associated protein 4 like
chr16_+_43152727 0.56 ENSDART00000125590
ENSDART00000154493
ADAM metallopeptidase domain 22
chr4_-_8903240 0.55 ENSDART00000129983
metallophosphoesterase domain containing 1
chr8_+_28593707 0.55 ENSDART00000097213
transcription factor 15
chr18_-_12957451 0.54 ENSDART00000140403
SLIT-ROBO Rho GTPase activating protein 1a
chr22_-_7400471 0.54 ENSDART00000161215
si:dkey-57c15.1
chr16_+_39159752 0.53 ENSDART00000122081
syntabulin (syntaxin-interacting)
chr14_-_40389699 0.53 ENSDART00000181581
ENSDART00000173398
protocadherin 19
chr20_+_27298783 0.51 ENSDART00000013861
protein phosphatase 4, regulatory subunit 4
chr6_-_13308813 0.51 ENSDART00000065372
potassium inwardly-rectifying channel, subfamily J, member 3b
chr22_-_11954861 0.50 ENSDART00000131611
si:dkeyp-4h4.1
chr12_+_46960579 0.49 ENSDART00000149032
ornithine aminotransferase
chr2_+_2563192 0.48 ENSDART00000055713

chr20_-_39188476 0.47 ENSDART00000152858
regulator of calcineurin 2
chr10_+_33895315 0.46 ENSDART00000142881
furry homolog b (Drosophila)
chr22_+_14051894 0.46 ENSDART00000142548
aldehyde oxidase 6
chr4_+_31259 0.45 ENSDART00000166826
putative homeodomain transcription factor 2
chr5_+_30624183 0.45 ENSDART00000141444
ATP-binding cassette, sub-family G (WHITE), member 4a
chr1_+_46194333 0.45 ENSDART00000010894
SRY (sex determining region Y)-box 1b
chr7_-_24699985 0.45 ENSDART00000052802
calbindin 2b
chr22_+_413349 0.44 ENSDART00000082453
cadherin, EGF LAG seven-pass G-type receptor 2
chr8_-_15398760 0.44 ENSDART00000162011
ATP/GTP binding protein-like 4
chr20_+_18225329 0.44 ENSDART00000144172
potassium channel tetramerization domain containing 1
chr17_+_15882533 0.43 ENSDART00000164124
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr6_+_41096058 0.42 ENSDART00000028373
FK506 binding protein 5
chr25_-_25736958 0.41 ENSDART00000166308
calcium and integrin binding family member 2
chr13_+_28705143 0.40 ENSDART00000183338
LIM domain binding 1a
chr5_-_46896541 0.40 ENSDART00000133240
EGF-like repeats and discoidin I-like domains 3a
chr19_-_31707892 0.40 ENSDART00000088427
RHO family interacting cell polarization regulator 2
chr18_+_7286788 0.39 ENSDART00000022998
si:ch73-86n2.1
chr17_+_33719415 0.38 ENSDART00000132294
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr18_+_38749547 0.38 ENSDART00000143735
si:ch211-215d8.2
chr6_+_45692026 0.37 ENSDART00000164759
contactin 4
chr1_+_7679328 0.37 ENSDART00000163488
ENSDART00000190070
engrailed homeobox 1b
chr5_-_25406807 0.36 ENSDART00000089748
RAR-related orphan receptor B
chr9_-_31915423 0.35 ENSDART00000060051
fibroblast growth factor 14
chr19_+_2726819 0.34 ENSDART00000187122
ENSDART00000112414
Rap guanine nucleotide exchange factor (GEF) 5a
chr22_+_18786797 0.34 ENSDART00000141864
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr22_+_18389271 0.34 ENSDART00000088270
YjeF N-terminal domain containing 3
chr15_+_39096736 0.33 ENSDART00000129511
ENSDART00000014877
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr21_-_30254185 0.33 ENSDART00000101054
DnaJ (Hsp40) homolog, subfamily C, member 18
chr21_-_25573064 0.33 ENSDART00000134310

chr1_+_1599979 0.33 ENSDART00000097626
urotensin II-related peptide
chr7_+_61050329 0.31 ENSDART00000115355
NACHT and WD repeat domain containing 2
chr9_-_18735256 0.31 ENSDART00000143165
TSC22 domain family, member 1
chr17_-_37052622 0.31 ENSDART00000186408
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr13_-_33822550 0.31 ENSDART00000143703
fibronectin leucine rich transmembrane 3
chr19_-_19556778 0.30 ENSDART00000164060
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr20_-_45060241 0.30 ENSDART00000185227
kelch-like family member 29
chr4_+_20255160 0.30 ENSDART00000188658
leucine-rich repeats and transmembrane domains 2a
chr25_-_26673570 0.29 ENSDART00000154917
circadian associated repressor of transcription b
chr24_-_40009446 0.29 ENSDART00000087422
amine oxidase, copper containing 1
chr17_+_20500229 0.29 ENSDART00000088490
neuralized E3 ubiquitin protein ligase 1Ab
chr15_+_42933236 0.28 ENSDART00000167763
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr16_-_26435431 0.28 ENSDART00000187526
multiple EGF-like-domains 8
chr11_-_35575791 0.28 ENSDART00000031441
ENSDART00000188513
ENSDART00000183609
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr15_-_30815826 0.27 ENSDART00000156160
ENSDART00000145918
musashi RNA-binding protein 2b
chr1_+_31725154 0.27 ENSDART00000112333
ENSDART00000189801
cyclin and CBS domain divalent metal cation transport mediator 2b
chr21_+_5888641 0.27 ENSDART00000091331
proline dehydrogenase (oxidase) 1a
chr9_-_21507083 0.27 ENSDART00000137922
AF4/FMR2 family, member 3
chr13_+_29773153 0.27 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
paired box 2a
chr6_-_19381993 0.27 ENSDART00000164114
growth factor receptor-bound protein 2a
chr18_+_660578 0.27 ENSDART00000161203
si:dkey-205h23.2
chr13_+_42406883 0.27 ENSDART00000084354
cytoplasmic polyadenylation element binding protein 3
chr4_-_9579299 0.26 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
SH3 and multiple ankyrin repeat domains 3b
chr9_+_34331368 0.26 ENSDART00000147913
POU class 2 homeobox 1b
chr7_+_10701938 0.26 ENSDART00000158162
aryl-hydrocarbon receptor nuclear translocator 2
chr25_-_15045338 0.26 ENSDART00000161165
ENSDART00000165774
ENSDART00000172538
paired box 6a
chr24_+_41931585 0.25 ENSDART00000130310
erythrocyte membrane protein band 4.1-like 3a
chr14_+_23874062 0.24 ENSDART00000172149
SH3 domain containing ring finger 2
chr13_-_24877577 0.24 ENSDART00000182705
K(lysine) acetyltransferase 6B
chr19_+_41464870 0.24 ENSDART00000102778
distal-less homeobox 6a
chr5_-_26323137 0.24 ENSDART00000133823
ARVCF, delta catenin family member b
chr15_-_18361475 0.24 ENSDART00000155866
zinc finger and BTB domain containing 16b
chr7_+_31074636 0.24 ENSDART00000173805
tight junction protein 1a
chr9_-_25444091 0.24 ENSDART00000002428
activin A receptor type 2Aa
chr4_+_12292274 0.24 ENSDART00000061070
ENSDART00000150786
makorin, ring finger protein, 1
chr13_+_28618086 0.23 ENSDART00000087001
cyclin and CBS domain divalent metal cation transport mediator 2a
chr1_+_8984068 0.23 ENSDART00000122568
toll-like receptor 2
chr14_-_34700633 0.23 ENSDART00000150358
actin binding LIM protein family, member 3
chr7_+_13824150 0.23 ENSDART00000035067
abhydrolase domain containing 2a
chr22_-_10397600 0.23 ENSDART00000181964
ENSDART00000142886
nischarin
chr13_+_29778610 0.23 ENSDART00000132004
paired box 2a
chr23_+_2825940 0.23 ENSDART00000135781
phospholipase C, gamma 1
chr11_+_25634041 0.22 ENSDART00000033657
glutamate receptor, metabotropic 6b
chr5_+_9147497 0.22 ENSDART00000003273
ring finger and CHY zinc finger domain containing 1
chr10_-_5821584 0.22 ENSDART00000166388
interleukin 6 signal transducer
chr16_+_25074029 0.22 ENSDART00000155465
si:dkeyp-84f3.9
chr7_+_25920792 0.21 ENSDART00000026295
arrestin, beta 2b
chr8_-_43574935 0.21 ENSDART00000051139
nuclear receptor corepressor 2
chr9_-_30502010 0.21 ENSDART00000149483
si:dkey-229b18.3
chr1_-_20593778 0.21 ENSDART00000124770
UDP glycosyltransferase 8
chr11_-_41130239 0.20 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr3_+_26223376 0.20 ENSDART00000128284
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr20_+_20751425 0.20 ENSDART00000177048
protein phosphatase 1, regulatory subunit 13Bb
chr7_-_26497947 0.20 ENSDART00000058910
SRY (sex determining region Y)-box 19b
chr12_+_16087077 0.20 ENSDART00000141898
zinc finger protein 281b
chr21_-_32467099 0.19 ENSDART00000186354
zgc:123105
chr17_-_25831569 0.19 ENSDART00000148743
hedgehog acyltransferase
chr6_-_54111928 0.19 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr1_-_24918686 0.19 ENSDART00000148076
F-box and WD repeat domain containing 7
chr18_+_22606259 0.19 ENSDART00000128965
breast cancer anti-estrogen resistance 1
chr14_-_48939560 0.19 ENSDART00000021736
short coiled-coil protein b
chr2_-_39036604 0.18 ENSDART00000129963
retinol binding protein 1b, cellular
chr10_+_33744098 0.18 ENSDART00000147775
relaxin/insulin-like family peptide receptor 2a
chr9_+_12444494 0.18 ENSDART00000102430
transmembrane protein 41aa
chr10_+_44940693 0.18 ENSDART00000157515
cyclin and CBS domain divalent metal cation transport mediator 4a
chr22_-_32392252 0.18 ENSDART00000148681
ENSDART00000137945
poly(rC) binding protein 4
chr23_+_20518504 0.17 ENSDART00000114246
activity-dependent neuroprotector homeobox b
chr7_+_20965880 0.17 ENSDART00000062003
ephrin-B3b
chr17_-_30473374 0.17 ENSDART00000155021
si:ch211-175f11.5
chr1_+_54013457 0.17 ENSDART00000012104
ENSDART00000126339
deltaA
chr1_-_31350148 0.17 ENSDART00000085370
potassium voltage-gated channel, KQT-like subfamily, member 5b
chr19_-_32042105 0.17 ENSDART00000088358
zinc finger protein 704
chr12_+_28986308 0.17 ENSDART00000153178
si:rp71-1c10.8
chr25_+_25737386 0.17 ENSDART00000108476
leucine rich repeat containing 61
chr19_-_26770083 0.17 ENSDART00000193811
ENSDART00000174455
proline-rich coiled-coil 2A
chr7_-_46777876 0.17 ENSDART00000193954
teashirt zinc finger homeobox 3b
chr7_-_4036184 0.16 ENSDART00000019949
NDRG family member 2
chr17_-_4245311 0.16 ENSDART00000055379
growth differentiation factor 3
chr19_-_26769867 0.16 ENSDART00000043776
ENSDART00000159489
ENSDART00000138675
proline-rich coiled-coil 2A
chr2_-_56131312 0.16 ENSDART00000097755
JunD proto-oncogene, AP-1 transcription factor subunit
chr23_-_36934944 0.16 ENSDART00000109976
ENSDART00000162179
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a
chr10_-_27196093 0.16 ENSDART00000185282
autism susceptibility candidate 2a
chr4_-_16406737 0.15 ENSDART00000013085
decorin
chr1_-_17587552 0.15 ENSDART00000039917
acyl-CoA synthetase long chain family member 1a
chr25_+_27923846 0.15 ENSDART00000047007
solute carrier family 13 member 1
chr8_+_8238727 0.14 ENSDART00000144838
plexin B3
chr11_+_21586335 0.14 ENSDART00000091182
zgc:101564
chr16_-_21620947 0.14 ENSDART00000115011
ENSDART00000183125
ENSDART00000188856
ENSDART00000189460
discoidin domain receptor tyrosine kinase 1
chr14_+_37545639 0.14 ENSDART00000173192
protocadherin 1b
chr5_+_63785339 0.14 ENSDART00000050871
regulator of G protein signaling 3b
chr10_+_42521943 0.14 ENSDART00000010420
ENSDART00000075303
ARP1 actin related protein 1, centractin
chr3_+_30190419 0.14 ENSDART00000157320
AKT1 substrate 1 (proline-rich)
chr3_-_21118969 0.13 ENSDART00000129016
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr6_+_18418651 0.13 ENSDART00000171097
ENSDART00000167798
RAB11 family interacting protein 4 (class II) b
chr20_-_2361226 0.13 ENSDART00000172130
si:ch73-18b11.1
chr24_-_37484123 0.13 ENSDART00000111623
clusterin associated protein 1
chr2_-_7185460 0.13 ENSDART00000092078
ring finger and CCCH-type domains 1b
chr1_+_27825980 0.13 ENSDART00000160524
paraspeckle component 1
chr15_-_1622468 0.12 ENSDART00000149008
ENSDART00000034456
karyopherin alpha 4 (importin alpha 3)
chr19_-_6239248 0.12 ENSDART00000014127
POU class 2 homeobox 2a
chr6_+_23935045 0.12 ENSDART00000162993
growth arrest and DNA-damage-inducible, alpha, b
chr14_-_28001986 0.12 ENSDART00000054115
TSC22 domain family, member 3
chr1_+_32051581 0.12 ENSDART00000146602
steroid sulfatase (microsomal), isozyme S
chr2_-_37684641 0.11 ENSDART00000012191
hippocampus abundant transcript 1a
chr2_-_3616363 0.11 ENSDART00000144699
phosphotriesterase related
chr7_+_69470442 0.11 ENSDART00000189593
GABA(A) receptor-associated protein b
chr8_+_31777633 0.11 ENSDART00000142519
3-oxoacid CoA transferase 1a
chr17_+_26352372 0.11 ENSDART00000155177
glutamate receptor, ionotropic, delta 1a
chr23_-_893547 0.11 ENSDART00000136805
RNA binding motif protein 10
chr16_+_49089123 0.11 ENSDART00000187494
phospholipase C like 2
chr25_+_5604512 0.11 ENSDART00000042781
plexin b2b
chr4_+_12013043 0.10 ENSDART00000130692
cryptochrome circadian clock 1aa
chr17_-_4245902 0.10 ENSDART00000151851
growth differentiation factor 3
chr21_+_26390549 0.10 ENSDART00000185643
thymosin, beta
chr10_+_39304422 0.10 ENSDART00000019267
potassium inwardly-rectifying channel, subfamily J, member 1b
chr10_-_26225548 0.10 ENSDART00000132019
ENSDART00000079194
ADP-ribosylation factor interacting protein 2b
chr5_+_69733096 0.10 ENSDART00000169013
ADP-ribosylation factor-like 6 interacting protein 4
chr16_+_34046733 0.10 ENSDART00000058424
family with sequence similarity 46, member Ba
chr21_-_35853245 0.10 ENSDART00000172245
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr22_-_18491813 0.10 ENSDART00000105419
si:ch211-212d10.2
chr1_-_40411944 0.10 ENSDART00000144135
mastermind-like transcriptional coactivator 3
chr23_-_26725637 0.10 ENSDART00000157844
heparan sulfate proteoglycan 2
chr21_+_8427059 0.10 ENSDART00000143151
DENN/MADD domain containing 1A
chr7_+_60396957 0.09 ENSDART00000121545
breast cancer metastasis suppressor 1
chr2_-_24317240 0.09 ENSDART00000078975
tRNA selenocysteine 1 associated protein 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of pou3f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.2 1.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 1.0 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.1 0.5 GO:0060074 synapse maturation(GO:0060074)
0.1 0.4 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.4 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.1 0.2 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.9 GO:0042044 fluid transport(GO:0042044)
0.1 0.7 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.2 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 0.5 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.5 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.2 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.2 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.3 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.3 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.2 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.4 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.1 GO:0021742 abducens nucleus development(GO:0021742)
0.0 0.2 GO:0055016 hypochord development(GO:0055016)
0.0 0.4 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.5 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.3 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.6 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.3 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 1.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.1 2.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.2 GO:0030141 secretory granule(GO:0030141)
0.0 1.1 GO:0042383 sarcolemma(GO:0042383)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.7 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0008126 acetylesterase activity(GO:0008126)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity