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PRJNA207719: Tissue specific transcriptome profiling

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Results for rfx1a+rfx1b

Z-value: 1.02

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Transcription factors associated with rfx1a+rfx1b

Gene Symbol Gene ID Gene Info
ENSDARG00000005883 regulatory factor X, 1a (influences HLA class II expression)
ENSDARG00000075904 regulatory factor X, 1b (influences HLA class II expression)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rfx1adr11_v1_chr3_-_19200571_192006510.903.9e-02Click!
rfx1bdr11_v1_chr1_-_54100988_541009880.069.3e-01Click!

Activity profile of rfx1a+rfx1b motif

Sorted Z-values of rfx1a+rfx1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_47193564 1.43 ENSDART00000172453
limbic system-associated membrane protein
chr3_-_5664123 1.04 ENSDART00000145866
si:ch211-106h11.1
chr15_+_22267847 0.95 ENSDART00000110665
sperm autoantigenic protein 17
chr19_+_2275019 0.93 ENSDART00000136138
integrin, beta 8
chr25_+_34407740 0.91 ENSDART00000012677
si:dkey-37f18.2
chr6_+_13933464 0.90 ENSDART00000109144
protein tyrosine phosphatase, receptor type, Nb
chr20_+_31076488 0.71 ENSDART00000136255
ENSDART00000008840
otoferlin a
chr11_-_1291012 0.68 ENSDART00000158390
ATPase plasma membrane Ca2+ transporting 2
chr17_+_23937262 0.66 ENSDART00000113276
si:ch211-189k9.2
chr1_+_8662530 0.66 ENSDART00000054989
fascin actin-bundling protein 1b
chr22_+_438714 0.66 ENSDART00000136491
cadherin, EGF LAG seven-pass G-type receptor 2
chr8_+_7144066 0.62 ENSDART00000146306
solute carrier family 6 (neurotransmitter transporter), member 6a
chr13_-_36911118 0.60 ENSDART00000048739
tripartite motif containing 9
chr13_-_31470439 0.60 ENSDART00000076574
reticulon 1a
chr23_+_6272638 0.59 ENSDART00000190366
synaptotagmin IIa
chr24_-_205275 0.59 ENSDART00000108762
VOPP1, WBP1/VOPP1 family member
chr18_-_46763170 0.59 ENSDART00000171880
delta/notch-like EGF repeat containing
chr7_+_23515966 0.58 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr21_-_43606502 0.56 ENSDART00000151030
si:ch73-362m14.4
chr4_+_19534833 0.56 ENSDART00000140028
leucine rich repeat containing 4.1
chr19_+_21266008 0.55 ENSDART00000024639
teashirt zinc finger homeobox 1
chr2_+_59527149 0.55 ENSDART00000168568

chr21_+_43669943 0.55 ENSDART00000136025
trimethyllysine hydroxylase, epsilon
chr16_+_5202042 0.54 ENSDART00000145368
SOGA family member 3a
chr15_+_36115955 0.54 ENSDART00000032702
somatostatin 1, tandem duplicate 2
chr14_+_6954579 0.53 ENSDART00000060998
NME/NM23 family member 5
chr11_-_18799827 0.53 ENSDART00000185438
ENSDART00000189116
ENSDART00000180504
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr17_-_29119362 0.52 ENSDART00000104204
forkhead box G1a
chr13_+_33117528 0.52 ENSDART00000085719
si:ch211-10a23.2
chr16_-_16590780 0.51 ENSDART00000059841
si:ch211-257p13.3
chr1_+_604127 0.51 ENSDART00000133165
junctional adhesion molecule 2a
chr5_-_38384755 0.50 ENSDART00000188573
ENSDART00000051233
misshapen-like kinase 1
chr21_+_9576176 0.48 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mitogen-activated protein kinase 10
chr18_-_2727764 0.48 ENSDART00000160841
si:ch211-248g20.5
chr15_-_12113045 0.48 ENSDART00000159879
Down syndrome cell adhesion molecule like 1
chr17_+_27176243 0.47 ENSDART00000162527
si:ch211-160f23.7
chr10_+_2234283 0.47 ENSDART00000136363
contactin associated protein like 3
chr18_+_49411417 0.46 ENSDART00000028944
zmp:0000001073
chr14_-_9199968 0.45 ENSDART00000146113
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr18_+_29950233 0.45 ENSDART00000146431
ATM interactor
chr12_+_13405445 0.44 ENSDART00000089042
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr2_+_33796207 0.44 ENSDART00000124647
KISS1 receptor a
chr22_+_3223489 0.44 ENSDART00000082011
lens intrinsic membrane protein 2.2
chr16_+_11483811 0.43 ENSDART00000169012
ENSDART00000173042
glutamate receptor, ionotropic, kainate 5
chr11_-_18800299 0.43 ENSDART00000156276
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr17_-_22067451 0.43 ENSDART00000156872
tau tubulin kinase 1b
chr16_+_34493987 0.43 ENSDART00000138374
si:ch211-255i3.4
chr19_-_8604429 0.42 ENSDART00000151165
tripartite motif containing 46b
chr17_+_33767890 0.42 ENSDART00000193177
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr6_+_13787855 0.41 ENSDART00000182899
transmembrane protein 198b
chr22_-_11438627 0.41 ENSDART00000007649
MID1 interacting protein 1b
chr8_-_9570511 0.41 ENSDART00000044000
plexin A3
chr16_+_46111849 0.41 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr20_-_27857676 0.41 ENSDART00000192934
synapse differentiation inducing 1-like
chr9_+_6009077 0.41 ENSDART00000057484
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr2_-_12502495 0.41 ENSDART00000186781
dipeptidyl-peptidase 6b
chr19_+_2279051 0.40 ENSDART00000182103
integrin, beta 8
chr10_-_29744921 0.39 ENSDART00000088605
intraflagellar transport 46 homolog (Chlamydomonas)
chr8_+_25267903 0.39 ENSDART00000093090
adenosine monophosphate deaminase 2b
chr11_-_24428237 0.38 ENSDART00000189107
ENSDART00000103752
dishevelled segment polarity protein 1b
chr11_+_7528599 0.38 ENSDART00000171813
adhesion G protein-coupled receptor L2a
chr13_-_18691041 0.38 ENSDART00000057867
sideroflexin 3
chr1_+_37752171 0.38 ENSDART00000183247
ENSDART00000189756
ENSDART00000139448
si:ch211-15e22.3
chr16_+_41717313 0.38 ENSDART00000015170
ENSDART00000075937
metadherin b
chr4_-_9557186 0.37 ENSDART00000150569
SH3 and multiple ankyrin repeat domains 3b
chr20_+_49787584 0.37 ENSDART00000193458
ENSDART00000181511
ENSDART00000185850
ENSDART00000185613
ENSDART00000191671

chr14_-_52542928 0.37 ENSDART00000075749
protein phosphatase 2, regulatory subunit B, beta a
chr5_-_38384289 0.36 ENSDART00000135260
misshapen-like kinase 1
chr22_+_25049563 0.36 ENSDART00000078173
double zinc ribbon and ankyrin repeat domains 1
chr17_-_11329959 0.36 ENSDART00000015418
interferon regulatory factor 2 binding protein-like
chr2_-_1569250 0.35 ENSDART00000167202
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr6_-_7711349 0.35 ENSDART00000032494
tetratricopeptide repeat domain 26
chr20_+_36682051 0.35 ENSDART00000130513
nuclear receptor coactivator 1
chr18_+_5917625 0.35 ENSDART00000169100
golgi glycoprotein 1b
chr5_+_32260502 0.35 ENSDART00000149020
si:ch211-158m24.12
chr20_-_12642685 0.35 ENSDART00000173257
si:dkey-97l20.6
chr10_+_15255012 0.34 ENSDART00000023766
very low density lipoprotein receptor
chr13_+_28854438 0.33 ENSDART00000193407
ENSDART00000189554

chr10_+_15255198 0.33 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr16_-_9869056 0.32 ENSDART00000149312
neurocalcin delta a
chr1_-_45633955 0.31 ENSDART00000044057
septin 3
chr11_-_30352333 0.31 ENSDART00000030794
transmembrane protein 169a
chr5_+_61919217 0.30 ENSDART00000097340
radial spoke head 4 homolog A
chr8_+_29749017 0.29 ENSDART00000185144
mitogen-activated protein kinase 4
chr25_+_18436301 0.29 ENSDART00000056180
centrosomal protein 41
chr4_-_1801519 0.29 ENSDART00000188604
ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr13_-_36184476 0.29 ENSDART00000057185
mitogen-activated protein kinase kinase kinase 9
chr24_-_39772045 0.29 ENSDART00000087441
si:ch211-276f18.2
chr1_+_594584 0.29 ENSDART00000135944
junctional adhesion molecule 2a
chr15_-_1534232 0.29 ENSDART00000056763
ENSDART00000133943
intraflagellar transport 80 homolog (Chlamydomonas)
chr11_-_36341189 0.28 ENSDART00000159752
sortilin 1a
chr8_-_49345388 0.28 ENSDART00000053203
proteolipid protein 2
chr17_+_8988374 0.28 ENSDART00000109573
A kinase (PRKA) anchor protein 6
chr7_-_34505985 0.28 ENSDART00000173806
ENSDART00000024869
testis expressed 9
chr9_-_41401564 0.28 ENSDART00000059628
NGFI-A binding protein 1b (EGR1 binding protein 1)
chr1_+_53279861 0.28 ENSDART00000035713
ring finger protein 150a
chr6_-_18250857 0.28 ENSDART00000159486
APC11 anaphase promoting complex subunit 11 homolog (yeast)
chr14_+_24283915 0.27 ENSDART00000172868
kelch-like family member 3
chr2_+_55914699 0.27 ENSDART00000157905
ataxia, cerebellar, Cayman type b
chr21_-_35832548 0.27 ENSDART00000180840
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr2_-_7696287 0.27 ENSDART00000190769

chr4_-_9579299 0.27 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
SH3 and multiple ankyrin repeat domains 3b
chr4_-_23858900 0.26 ENSDART00000123199
USP6 N-terminal like
chr14_-_21219659 0.26 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr2_-_7696503 0.26 ENSDART00000169709

chr21_+_13387965 0.26 ENSDART00000134347
zgc:113162
chr19_+_17400283 0.26 ENSDART00000127353
nuclear receptor subfamily 1, group D, member 2b
chr11_-_28911172 0.25 ENSDART00000168493
immunoglobin superfamily, member 21a
chr9_+_9112159 0.25 ENSDART00000165932
salt-inducible kinase 1
chr9_+_40874194 0.25 ENSDART00000141548
3-hydroxyisobutyryl-CoA hydrolase
chr3_-_46410387 0.25 ENSDART00000156822
cell death-inducing p53 target 1
chr17_+_53250802 0.24 ENSDART00000143819
vasohibin 1
chr16_+_9726038 0.24 ENSDART00000192988
ENSDART00000020859
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr24_+_39186940 0.24 ENSDART00000155817
splA/ryanodine receptor domain and SOCS box containing 3b
chr8_-_50525360 0.23 ENSDART00000175648

chr23_-_12158685 0.23 ENSDART00000135035
family with sequence similarity 217, member B
chr21_+_22124736 0.23 ENSDART00000130179
ENSDART00000172573
cullin 5b
chr3_-_61593274 0.23 ENSDART00000154132
ENSDART00000055071
neuronal pentraxin 2a
chr7_+_27059330 0.23 ENSDART00000173919
pleckstrin homology domain containing, family A member 7b
chr1_-_49498116 0.23 ENSDART00000137357
zgc:175214
chr17_-_8173380 0.22 ENSDART00000148520
spectrin repeat containing, nuclear envelope 1b
chr1_+_47831619 0.21 ENSDART00000110335
ENSDART00000101066
cilia and flagella associated protein 58
chr15_+_31735931 0.21 ENSDART00000185681
ENSDART00000149137
relaxin/insulin-like family peptide receptor 2b
chr1_-_21538329 0.21 ENSDART00000182798
ENSDART00000193518
ENSDART00000183873
ENSDART00000183376
WD repeat domain 19
chr21_-_435466 0.21 ENSDART00000110297
Kruppel-like factor 4
chr24_+_38155830 0.21 ENSDART00000152019
si:ch211-234p6.5
chr3_-_12026741 0.21 ENSDART00000132238
cilia and flagella associated protein 70
chr10_-_7988396 0.20 ENSDART00000141445
ENSDART00000024282
EWS RNA-binding protein 1a
chr1_+_50538839 0.20 ENSDART00000020412
polycystic kidney disease 2
chr11_+_77526 0.20 ENSDART00000193521

chr23_+_21638258 0.20 ENSDART00000104188
immunoglobin superfamily, member 21b
chr17_-_14451718 0.20 ENSDART00000039438
jnk1/mapk8 associated membrane protein
chr1_-_21538673 0.20 ENSDART00000131257
WD repeat domain 19
chr11_+_24800156 0.20 ENSDART00000131976
adiponectin receptor 1a
chr20_-_31075972 0.20 ENSDART00000122927
si:ch211-198b3.4
chr16_+_13898399 0.20 ENSDART00000140946
si:ch211-149k23.9
chr25_-_20523927 0.19 ENSDART00000114448
si:ch211-269c21.2
chr23_+_44665230 0.19 ENSDART00000144958
calmodulin binding transcription activator 2
chr18_+_50890749 0.19 ENSDART00000174109
si:ch1073-450f2.1
chr6_+_515181 0.19 ENSDART00000171374
si:ch73-379f7.5
chr17_+_33296852 0.19 ENSDART00000154580
DnaJ (Hsp40) homolog, subfamily C, member 27
chr13_+_31205439 0.19 ENSDART00000132326
protein tyrosine phosphatase, non-receptor type 20
chr1_-_46718353 0.19 ENSDART00000074514
SPRY domain containing 7a
chr18_-_50579629 0.18 ENSDART00000188252
zgc:158464
chr13_-_4303641 0.18 ENSDART00000136262
protein phosphatase 2, regulatory subunit B', delta
chr20_-_4766645 0.18 ENSDART00000147071
ENSDART00000152398
adenylate kinase 7a
chr13_+_13805385 0.18 ENSDART00000166859
solute carrier family 4, sodium borate transporter, member 11
chr6_-_41138854 0.18 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
solute carrier family 6 member 22, tandem duplicate 1
chr17_+_33296436 0.17 ENSDART00000123114
DnaJ (Hsp40) homolog, subfamily C, member 27
chr15_-_43768776 0.17 ENSDART00000170398
glutamate receptor, metabotropic 5b
chr21_+_17005737 0.17 ENSDART00000101246
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr4_+_74002176 0.17 ENSDART00000163662
si:cabz01069013.3
chr6_-_58901552 0.17 ENSDART00000122003
methyl-CpG binding domain protein 6
chr17_-_12758171 0.16 ENSDART00000131564
breast cancer metastasis-suppressor 1-like a
chr23_+_10469955 0.16 ENSDART00000140557
tensin 2a
chr6_+_18418651 0.16 ENSDART00000171097
ENSDART00000167798
RAB11 family interacting protein 4 (class II) b
chr18_-_17531483 0.16 ENSDART00000061000
Bardet-Biedl syndrome 2
chr20_-_2361226 0.16 ENSDART00000172130
si:ch73-18b11.1
chr24_-_9960290 0.16 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr4_+_10616626 0.16 ENSDART00000067251
ENSDART00000143690
cadherin-like and PC-esterase domain containing 1
chr13_+_48482256 0.15 ENSDART00000053332
forkhead box N2
chr12_+_4971515 0.15 ENSDART00000161076
Rho GTPase activating protein 27
chr8_-_22838364 0.15 ENSDART00000187954
ENSDART00000185368
ENSDART00000188210
MAGI family member, X-linked a
chr18_-_31051847 0.15 ENSDART00000170982
growth arrest-specific 8
chr17_+_27545183 0.15 ENSDART00000129392
PARK2 co-regulated
chr18_+_30028637 0.15 ENSDART00000139750
si:ch211-220f16.1
chr25_+_3868438 0.15 ENSDART00000156438
transmembrane protein 138
chr18_-_44359726 0.15 ENSDART00000166935
PR domain containing 10
chr14_+_24277556 0.14 ENSDART00000122660
heterogeneous nuclear ribonucleoprotein A0a
chr20_+_4060839 0.14 ENSDART00000178565
tripartite motif containing 67
chr5_+_43807003 0.14 ENSDART00000097625
zgc:158640
chr10_+_37981471 0.14 ENSDART00000113112
ENSDART00000185102
WSC domain containing 1b
chr7_-_41881177 0.14 ENSDART00000174258
ENSDART00000018972
zgc:92818
chr3_+_24458899 0.14 ENSDART00000156655
chromobox homolog 6b
chr17_-_33716688 0.14 ENSDART00000043651
dynein, axonemal, light chain 1
chr23_+_37185247 0.14 ENSDART00000146269
von Willebrand factor A domain containing 5B1
chr19_+_27589201 0.14 ENSDART00000182060
si:dkeyp-46h3.1
chr8_-_14080534 0.13 ENSDART00000042867
death effector domain containing
chr21_+_3244146 0.13 ENSDART00000127740
CBP80/20-dependent translation initiation factor
chr10_-_36682509 0.13 ENSDART00000148093
ENSDART00000063365
DnaJ (Hsp40) homolog, subfamily B, member 13
chr24_+_744713 0.13 ENSDART00000067764
serine/threonine kinase 17a
chr12_+_28955766 0.13 ENSDART00000123417
ENSDART00000139347
zinc finger protein 668
chr25_+_5755314 0.12 ENSDART00000172088
ENSDART00000164208
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr10_+_15608326 0.12 ENSDART00000188770
zinc finger, AN1-type domain 5b
chr7_-_34192834 0.12 ENSDART00000125131
SMAD family member 6a
chr4_-_30362840 0.12 ENSDART00000165929
zinc finger protein 1083
chr8_-_19216180 0.11 ENSDART00000146162
si:ch73-222f22.2
chr6_-_46560207 0.11 ENSDART00000187607
potassium voltage-gated channel, Shab-related subfamily, member 1
chr2_-_36819624 0.11 ENSDART00000140844
SLIT and NTRK-like family, member 3b
chr10_-_74408 0.11 ENSDART00000100073
ENSDART00000141723
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
chr16_-_11779508 0.11 ENSDART00000136329
ENSDART00000060145
ENSDART00000141101
platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit
chr22_-_20720427 0.11 ENSDART00000105532
ornithine decarboxylase antizyme 1a
chr18_+_16133595 0.11 ENSDART00000080423
cathepsin D
chr10_+_2529037 0.10 ENSDART00000123467
zmp:0000001301
chr12_+_17620067 0.10 ENSDART00000073599
radial spoke head 10 homolog B
chr4_-_3145359 0.10 ENSDART00000112210
pleckstrin homology domain containing, family A member 5
chr3_+_60044780 0.10 ENSDART00000080437
zgc:113030
chr23_+_2760573 0.10 ENSDART00000129719
DNA topoisomerase I
chr10_-_17231917 0.10 ENSDART00000038577
RAB36, member RAS oncogene family
chr2_+_41526904 0.10 ENSDART00000127520
activin A receptor, type 1 like

Network of associatons between targets according to the STRING database.

First level regulatory network of rfx1a+rfx1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.2 0.5 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.1 0.6 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.3 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 1.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.5 GO:0043584 nose development(GO:0043584)
0.1 1.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.3 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.7 GO:0001964 startle response(GO:0001964)
0.1 0.4 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.7 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.4 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 1.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.4 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.2 GO:0035889 otolith tethering(GO:0035889)
0.0 0.1 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.3 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.5 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.3 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.3 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 1.4 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.1 GO:0070293 renal absorption(GO:0070293)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.3 GO:0001534 radial spoke(GO:0001534)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.2 GO:0010369 chromocenter(GO:0010369)
0.1 0.4 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.0 2.1 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0070724 BMP receptor complex(GO:0070724)
0.0 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.8 GO:0031514 motile cilium(GO:0031514)
0.0 0.7 GO:0030426 growth cone(GO:0030426)
0.0 0.6 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.9 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0099569 presynaptic cytoskeleton(GO:0099569)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.4 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.2 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK