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PRJNA207719: Tissue specific transcriptome profiling

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Results for spi1a+spi1b

Z-value: 4.41

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Transcription factors associated with spi1a+spi1b

Gene Symbol Gene ID Gene Info
ENSDARG00000000767 Spi-1 proto-oncogene b
ENSDARG00000067797 Spi-1 proto-oncogene a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
spi1bdr11_v1_chr7_-_32659048_326590480.781.2e-01Click!
spi1adr11_v1_chr25_+_35553542_355535420.583.0e-01Click!

Activity profile of spi1a+spi1b motif

Sorted Z-values of spi1a+spi1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_10177442 4.26 ENSDART00000144280
ENSDART00000129044
keratin 5
chr3_+_40809011 3.23 ENSDART00000033713
actin related protein 2/3 complex, subunit 1B
chr20_+_38285671 2.73 ENSDART00000061432
chemokine (C-C motif) ligand 38, duplicate 4
chr15_-_29598679 2.58 ENSDART00000155153
si:ch211-207n23.2
chr3_-_30941362 2.53 ENSDART00000076830
coronin, actin binding protein, 1A
chr6_-_49063085 2.41 ENSDART00000156124
si:ch211-105j21.9
chr15_+_20239141 2.39 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr23_+_44599012 2.30 ENSDART00000125198
profilin 1
chr5_+_43783360 2.29 ENSDART00000019431
nitric oxide synthase 2a, inducible
chr10_+_2669405 2.19 ENSDART00000110202
chemokine (C-C motif) ligand 27b
chr7_-_34265481 2.18 ENSDART00000173596
si:ch211-98n17.5
chr6_-_8489810 2.15 ENSDART00000124643
RAS protein activator like 3
chr22_-_13350240 2.11 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
chr3_-_32859335 2.05 ENSDART00000158916
si:dkey-16l2.20
chr7_-_49892991 2.02 ENSDART00000126240
CD44 molecule (Indian blood group) a
chr9_-_56272465 1.99 ENSDART00000039235
lymphocyte cytosolic protein 1 (L-plastin)
chr15_-_29598444 1.98 ENSDART00000154847
si:ch211-207n23.2
chr5_-_25582721 1.97 ENSDART00000123986
annexin A1a
chr16_+_29492749 1.93 ENSDART00000179680
cathepsin K
chr24_-_31904924 1.91 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr16_-_31756859 1.91 ENSDART00000149170
ENSDART00000126617
ENSDART00000182722
protein tyrosine phosphatase, non-receptor type 6
chr19_-_40198478 1.90 ENSDART00000191736
granulin 2
chr22_+_5478353 1.90 ENSDART00000160596
tubulin polymerization promoting protein
chr21_+_25765734 1.89 ENSDART00000021664
claudin b
chr20_+_46040666 1.88 ENSDART00000060744
si:dkey-7c18.24
chr7_-_5316901 1.86 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
chr20_+_38276690 1.85 ENSDART00000061437
chemokine (C-C motif) ligand 38, duplicate 6
chr5_+_37087583 1.85 ENSDART00000049900
transgelin 2
chr10_+_38417512 1.84 ENSDART00000112457
SAM domain, SH3 domain and nuclear localisation signals 1b
chr3_+_29942338 1.81 ENSDART00000158220
interferon-induced protein 35
chr15_+_46356879 1.79 ENSDART00000154388
wu:fb18f06
chr24_-_31306724 1.77 ENSDART00000165399
acid phosphatase 5b, tartrate resistant
chr3_+_18579806 1.77 ENSDART00000180967
ENSDART00000089765
Rho GTPase activating protein 17b
chr16_-_41990421 1.76 ENSDART00000055921
PYD and CARD domain containing
chr16_+_17715243 1.74 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
chr4_-_22310956 1.72 ENSDART00000162585
hematopoietic cell-specific Lyn substrate 1
chr7_+_20563305 1.69 ENSDART00000169661
si:dkey-19b23.10
chr7_+_19482084 1.69 ENSDART00000173873
si:ch211-212k18.7
chr2_+_24762567 1.68 ENSDART00000078866
interferon, gamma-inducible protein 30
chr17_-_6202816 1.66 ENSDART00000151908
protein tyrosine kinase 2 beta, a
chr19_-_15192638 1.64 ENSDART00000048151
phosphatase and actin regulator 4a
chr8_-_54077740 1.64 ENSDART00000027000
rhodopsin
chr6_-_10788065 1.63 ENSDART00000190968
WAS/WASL interacting protein family, member 1b
chr11_-_21404044 1.63 ENSDART00000080116
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr9_-_443451 1.62 ENSDART00000165642
si:dkey-11f4.14
chr9_+_41224100 1.62 ENSDART00000141792
signal transducer and activator of transcription 1b
chr3_+_29510818 1.61 ENSDART00000055407
ENSDART00000193743
ENSDART00000123619
Rac family small GTPase 2
chr11_+_44135351 1.60 ENSDART00000182914

chr15_+_12435975 1.60 ENSDART00000168011
transmembrane protease, serine 4a
chr16_+_48753664 1.58 ENSDART00000155148
si:ch73-31d8.2
chr21_+_28747236 1.57 ENSDART00000137874
zgc:100829
chr9_+_21165017 1.55 ENSDART00000145933
ENSDART00000142985
si:rp71-68n21.9
chr20_-_19864131 1.54 ENSDART00000057819
protein tyrosine kinase 2 beta, b
chr14_+_29769336 1.53 ENSDART00000105898
si:dkey-34l15.1
chr7_+_15736230 1.50 ENSDART00000109942
multiple C2 domains, transmembrane 2b
chr3_+_36275633 1.50 ENSDART00000185027
ENSDART00000149532
ENSDART00000102883
ENSDART00000148444
zgc:86896
chr23_+_26142807 1.48 ENSDART00000158878
protein tyrosine phosphatase, non-receptor type 22
chr8_-_4586696 1.46 ENSDART00000143511
ENSDART00000134324
glycoprotein Ib (platelet), beta polypeptide
chr10_-_22127942 1.45 ENSDART00000133374
plac8 onzin related protein 2
chr12_-_28983584 1.45 ENSDART00000112374
zgc:171713
chr15_+_12436220 1.45 ENSDART00000169894
transmembrane protease, serine 4a
chr10_-_20650302 1.44 ENSDART00000142028
ENSDART00000064662
Ras association (RalGDS/AF-6) domain family member 2b
chr11_-_22303678 1.44 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr10_-_41980797 1.44 ENSDART00000076575
ras homolog family member F
chr8_-_28349859 1.42 ENSDART00000062671
tubulin, alpha 8 like
chr22_+_5687615 1.42 ENSDART00000133241
ENSDART00000019854
ENSDART00000138102
deoxyribonuclease 1 like 4, tandem duplicate 2
chr7_-_35066457 1.41 ENSDART00000058067
zgc:112160
chr23_+_26142613 1.41 ENSDART00000165046
protein tyrosine phosphatase, non-receptor type 22
chr13_+_8840772 1.41 ENSDART00000059321
epithelial cell adhesion molecule
chr21_+_28747069 1.41 ENSDART00000014058
zgc:100829
chr25_+_34014523 1.41 ENSDART00000182856
annexin A2a
chr7_+_34794829 1.41 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
epithelial splicing regulatory protein 2
chr7_+_49695904 1.38 ENSDART00000183550
ENSDART00000126991
achaete-scute family bHLH transcription factor 1b
chr7_-_26603743 1.36 ENSDART00000099003
phospholipid scramblase 3b
chr5_-_42272517 1.36 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
chr8_-_19975087 1.36 ENSDART00000182220
leupaxin
chr8_+_32406885 1.34 ENSDART00000167600
epithelial mitogen homolog (mouse)
chr23_+_31815423 1.33 ENSDART00000075730
ENSDART00000075726
v-myb avian myeloblastosis viral oncogene homolog
chr10_-_15128771 1.32 ENSDART00000101261
secreted phosphoprotein 1
chr4_-_77561679 1.31 ENSDART00000180809

chr3_+_40809892 1.28 ENSDART00000190803
actin related protein 2/3 complex, subunit 1B
chr9_+_23772516 1.25 ENSDART00000183126
si:ch211-219a4.3
chr4_-_55728559 1.24 ENSDART00000186201

chr2_-_6548838 1.24 ENSDART00000052419
regulator of G protein signaling 18
chr3_+_52737565 1.23 ENSDART00000108639
GEM interacting protein
chr14_+_23709543 1.23 ENSDART00000136909
glucosamine-6-phosphate deaminase 1
chr12_+_22576404 1.23 ENSDART00000172053
capping protein (actin filament), gelsolin-like b
chr19_+_10603405 1.23 ENSDART00000151135
si:dkey-211g8.8
chr17_-_2039511 1.23 ENSDART00000160223
serine peptidase inhibitor, Kunitz type 1 a
chr16_-_36099492 1.22 ENSDART00000180905

chr5_-_26879302 1.22 ENSDART00000098571
ENSDART00000139086
zgc:64051
chr9_-_25993849 1.22 ENSDART00000144840
Rho GTPase activating protein 15
chr19_-_18626515 1.22 ENSDART00000160624
ribosomal protein S18
chr4_-_22311610 1.22 ENSDART00000137814
hematopoietic cell-specific Lyn substrate 1
chr12_+_38878830 1.21 ENSDART00000156926
si:ch211-39f2.3
chr13_-_15994419 1.20 ENSDART00000079724
ENSDART00000042377
ENSDART00000046079
ENSDART00000050481
ENSDART00000016430
IKAROS family zinc finger 1 (Ikaros)
chr10_+_13209580 1.20 ENSDART00000000887
ENSDART00000136932
Ras association (RalGDS/AF-6) domain family 6
chr3_-_53508580 1.20 ENSDART00000073978
zgc:171711
chr11_+_141504 1.19 ENSDART00000086166
zgc:172352
chr21_-_22689805 1.19 ENSDART00000157560
ENSDART00000110792
grass carp reovirus (GCRV)-induced gene 2e
chr19_-_325584 1.18 ENSDART00000134266
glycerol-3-phosphate dehydrogenase 1c
chr7_-_7810348 1.18 ENSDART00000171984
chemokine (C-X-C motif) ligand 19
chr14_-_11529311 1.18 ENSDART00000127208
si:ch211-153b23.7
chr14_-_33348221 1.18 ENSDART00000187749
ribosomal protein L39
chr25_+_13205878 1.17 ENSDART00000162319
ENSDART00000162283
si:ch211-147m6.2
chr22_-_1079773 1.17 ENSDART00000136668
si:ch1073-15f12.3
chr18_-_26894732 1.17 ENSDART00000147735
ENSDART00000188938

si:dkey-24l11.2
chr3_+_24641489 1.17 ENSDART00000055590
ENSDART00000186635
zgc:113411
chr9_+_24088062 1.17 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr14_+_35428152 1.16 ENSDART00000172597
synaptotagmin-like 4
chr6_+_28141135 1.15 ENSDART00000113405
ENSDART00000179795
inositol polyphosphate-5-phosphatase D
chr9_+_30387930 1.15 ENSDART00000112827
si:dkey-18p12.4
chr7_+_49664174 1.14 ENSDART00000137059
ENSDART00000131210
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr4_+_77661056 1.14 ENSDART00000152953
si:dkey-61p9.7
chr25_+_18475032 1.14 ENSDART00000073564
testis derived transcript (3 LIM domains)
chr17_+_6217704 1.14 ENSDART00000129100

chr10_+_26667475 1.13 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
chr19_-_34927201 1.13 ENSDART00000076518
Src-like-adaptor 1
chr15_-_2652640 1.13 ENSDART00000146094
claudin f
chr25_-_16589461 1.12 ENSDART00000064204
carboxypeptidase A4
chr10_-_7785930 1.12 ENSDART00000043961
ENSDART00000111058
myeloid-specific peroxidase
chr15_-_4528326 1.12 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr16_+_29492937 1.12 ENSDART00000011497
cathepsin K
chr10_-_24648228 1.11 ENSDART00000081834
ENSDART00000132830
stomatin (EPB72)-like 3b
chr19_+_40350468 1.11 ENSDART00000087444
HEPACAM family member 2
chr5_+_9360394 1.11 ENSDART00000124642

chr22_+_3914318 1.11 ENSDART00000188774
ENSDART00000082034
Danio rerio major histocompatibility complex class I ULA (mhc1ula), mRNA.
chr10_+_28428222 1.11 ENSDART00000135003
si:ch211-222e20.4
chr7_+_19600262 1.10 ENSDART00000007310
zgc:171731
chr16_+_31542645 1.10 ENSDART00000163724
Src like adaptor
chr14_-_33585809 1.10 ENSDART00000023540
SAM and SH3 domain containing 3
chr8_+_19356072 1.10 ENSDART00000063272
macrophage expressed 1, tandem duplicate 2
chr19_+_43297546 1.09 ENSDART00000168002
lysosomal protein transmembrane 5
chr9_+_2499627 1.09 ENSDART00000160782
WAS/WASL interacting protein family, member 1a
chr2_-_36933472 1.09 ENSDART00000170405

chr21_+_15723069 1.08 ENSDART00000149126
ENSDART00000130628
purinergic receptor P2X, ligand-gated ion channel, 4a
chr13_+_27328098 1.08 ENSDART00000037585
Mab-21 domain containing 1
chr13_-_45523026 1.08 ENSDART00000020663
Rh blood group, D antigen
chr3_-_26978793 1.08 ENSDART00000155396
nucleotide binding protein 1 (MinD homolog, E. coli)
chr9_+_14010823 1.08 ENSDART00000143837
si:ch211-67e16.3
chr1_-_56213723 1.07 ENSDART00000142505
ENSDART00000137237
si:dkey-76b14.2
chr21_+_30937690 1.07 ENSDART00000022562
ras homolog family member Gb
chr16_+_38201840 1.07 ENSDART00000044971
myosin IE, b
chr10_+_44956660 1.07 ENSDART00000169225
ENSDART00000189298
interleukin 1, beta
chr15_-_3963649 1.06 ENSDART00000172146
ENSDART00000171738
G protein-coupled receptor 171
chr9_-_33877476 1.06 ENSDART00000150035
ENSDART00000088441
ENSDART00000183210
si:ch73-147f11.1
chr2_-_44777592 1.06 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr22_-_17652112 1.05 ENSDART00000189205
histocompatibility (minor) HA-1 b
chr7_+_29115890 1.05 ENSDART00000052345
tnfrsf1a-associated via death domain
chr1_-_45157243 1.05 ENSDART00000131882
mucin, multiple PTS and SEA group, member 1
chr21_-_25295087 1.05 ENSDART00000087910
ENSDART00000147860
suppression of tumorigenicity 14 (colon carcinoma) b
chr7_+_26029672 1.05 ENSDART00000101126
arachidonate 12-lipoxygenase
chr25_+_5068442 1.04 ENSDART00000097522
parvin, gamma
chr8_+_20880848 1.04 ENSDART00000134488
ENSDART00000138605
ENSDART00000192234
si:ch73-196i15.3
chr25_-_3228025 1.04 ENSDART00000165924
calcium and integrin binding 1 (calmyrin)
chr7_-_38658411 1.04 ENSDART00000109463
ENSDART00000017155
nephrosin
chr9_-_54304684 1.03 ENSDART00000109512
interleukin 13
chr8_-_36469117 1.03 ENSDART00000111240
major histocompatibility complex class II DAB gene
chr19_+_7120380 1.02 ENSDART00000000698
proteasome subunit beta 9a
chr23_+_44049509 1.02 ENSDART00000102003
TXK tyrosine kinase
chr25_-_16600811 1.02 ENSDART00000011397
carboxypeptidase A2 (pancreatic)
chr17_-_48705993 1.02 ENSDART00000030934
potassium channel, subfamily K, member 5a
chr22_-_15577060 1.01 ENSDART00000176291
hematopoietic SH2 domain containing
chr21_-_41025340 1.00 ENSDART00000148231
PLAC8-like 1
chr19_+_43716607 1.00 ENSDART00000133199
CAP, adenylate cyclase-associated protein 1 (yeast)
chr14_+_21222287 1.00 ENSDART00000159905
si:ch211-175m2.4
chr12_-_30558694 1.00 ENSDART00000153417
si:ch211-28p3.3
chr20_-_51307815 0.99 ENSDART00000098833
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr19_-_15192840 0.99 ENSDART00000151337
phosphatase and actin regulator 4a
chr1_+_40308077 0.99 ENSDART00000138992
von Willebrand factor A domain containing 10, tandem duplicate 2
chr19_-_12404590 0.99 ENSDART00000103703
finTRIM family, member 56
chr6_+_112579 0.99 ENSDART00000034505
adaptor-related protein complex 1, mu 2 subunit
chr21_+_27448856 0.98 ENSDART00000100784
complement factor b-like
chr5_+_42280372 0.98 ENSDART00000142855
T-box 6, like
chr18_+_22109379 0.98 ENSDART00000147230
zgc:158868
chr15_+_34963316 0.98 ENSDART00000153840
si:ch73-95l15.5
chr19_+_43715911 0.98 ENSDART00000006344
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_54180516 0.97 ENSDART00000149945
ribosomal protein S10
chr21_+_30306369 0.97 ENSDART00000145050
ENSDART00000059420
lymphocyte cytosolic protein 2a
chr3_+_30980852 0.97 ENSDART00000028529
perforin 1.1
chr22_+_18530395 0.97 ENSDART00000105415
ENSDART00000183958
si:ch211-212d10.1
chr10_+_4987766 0.97 ENSDART00000121959
si:ch73-234b20.5
chr6_-_425378 0.96 ENSDART00000192190
family with sequence similarity 83, member Fb
chr7_-_26601307 0.96 ENSDART00000188934
phospholipid scramblase 3b
chr4_+_7677318 0.96 ENSDART00000149218
ELK3, ETS-domain protein
chr15_-_18209672 0.96 ENSDART00000141508
ENSDART00000136280
bloodthirsty-related gene family, member 16
chr13_+_28785814 0.95 ENSDART00000039028
NSE4 homolog A, SMC5-SMC6 complex component
chr17_-_5860222 0.95 ENSDART00000058894
si:ch73-340m8.2
chr20_+_26683933 0.95 ENSDART00000139852
ENSDART00000077751
forkhead box Q1b
chr24_-_6078222 0.95 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_+_57787642 0.94 ENSDART00000127091
si:dkey-1c7.2
chr18_+_20567542 0.94 ENSDART00000182585
BH3 interacting domain death agonist
chr16_+_35401543 0.93 ENSDART00000171608
RAB42, member RAS oncogene family
chr2_-_41964402 0.93 ENSDART00000131278
si:dkey-97a13.6
chr11_+_1602916 0.92 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
chr11_+_26375979 0.92 ENSDART00000087652
ENSDART00000171748
ENSDART00000103513
ENSDART00000165931
ENSDART00000170043
copine I
RNA binding motif protein 12
chr13_-_32898962 0.91 ENSDART00000163757
rho-associated, coiled-coil containing protein kinase 2a
chr24_+_12945803 0.90 ENSDART00000005105
proteasome activator subunit 1
chr15_-_29573267 0.90 ENSDART00000099947
SAM domain, SH3 domain and nuclear localisation signals 1a
chr11_+_8129536 0.90 ENSDART00000158112
ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a

Network of associatons between targets according to the STRING database.

First level regulatory network of spi1a+spi1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.5 1.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4 1.7 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.4 1.3 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.4 0.8 GO:0042113 B cell activation(GO:0042113)
0.4 1.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.4 2.3 GO:0030828 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.4 1.1 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138)
0.4 2.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 2.3 GO:1902623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.3 2.0 GO:0033029 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 1.6 GO:2000391 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.3 1.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3 1.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.3 0.9 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) mediolateral intercalation(GO:0060031)
0.3 6.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.3 1.2 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.3 1.7 GO:0070254 mucus secretion(GO:0070254)
0.3 1.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.3 1.3 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.3 1.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 0.8 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.3 1.0 GO:0042267 natural killer cell mediated immunity(GO:0002228) regulation of natural killer cell mediated immunity(GO:0002715) positive regulation of natural killer cell mediated immunity(GO:0002717) natural killer cell mediated cytotoxicity(GO:0042267) regulation of natural killer cell mediated cytotoxicity(GO:0042269) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.3 0.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 1.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 5.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 2.5 GO:0045453 bone resorption(GO:0045453)
0.2 1.3 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.2 0.6 GO:0002369 T cell cytokine production(GO:0002369)
0.2 1.9 GO:0009188 ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.2 0.8 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 0.8 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 1.7 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 0.9 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.2 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.2 0.9 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 0.5 GO:0043525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2 1.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.2 0.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 2.2 GO:0007172 signal complex assembly(GO:0007172)
0.2 0.5 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.2 0.5 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.2 2.0 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 1.3 GO:0036372 opsin transport(GO:0036372)
0.2 0.7 GO:0045123 cellular extravasation(GO:0045123)
0.2 7.0 GO:0002548 monocyte chemotaxis(GO:0002548)
0.2 2.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 2.0 GO:0030810 positive regulation of cyclic nucleotide metabolic process(GO:0030801) positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of cyclase activity(GO:0031281) positive regulation of lyase activity(GO:0051349) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.2 0.7 GO:0002639 regulation of immunoglobulin production(GO:0002637) positive regulation of immunoglobulin production(GO:0002639)
0.2 0.5 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.2 0.8 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.2 1.1 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.2 1.5 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.2 0.5 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.2 0.3 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.2 2.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 0.6 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 0.5 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.4 GO:0034341 response to interferon-gamma(GO:0034341) cellular response to interferon-gamma(GO:0071346)
0.1 1.0 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.9 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.8 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:1901052 sarcosine metabolic process(GO:1901052)
0.1 1.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.5 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.5 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.6 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 1.4 GO:0090279 regulation of calcium ion import(GO:0090279)
0.1 2.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 1.2 GO:0051125 regulation of actin nucleation(GO:0051125)
0.1 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 1.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 2.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.7 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 3.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.1 0.4 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.9 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.2 GO:0045730 respiratory burst(GO:0045730)
0.1 0.7 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.5 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 1.5 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 0.3 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.1 0.5 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.1 0.7 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.3 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 2.0 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.9 GO:0030104 water homeostasis(GO:0030104)
0.1 0.4 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.4 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.1 2.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.0 GO:0046348 amino sugar catabolic process(GO:0046348)
0.1 2.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.4 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 0.5 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 0.3 GO:0045940 thyroid hormone generation(GO:0006590) positive regulation of steroid biosynthetic process(GO:0010893) positive regulation of steroid metabolic process(GO:0045940)
0.1 0.5 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 1.1 GO:0033198 response to ATP(GO:0033198)
0.1 0.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.5 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 1.0 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 2.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 1.1 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.1 0.3 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 2.2 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.1 1.1 GO:0019835 cytolysis(GO:0019835)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.2 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 1.0 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 1.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.1 0.5 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 1.2 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.1 1.0 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.1 GO:0006953 acute-phase response(GO:0006953)
0.1 0.6 GO:1900026 regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.2 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.7 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.6 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.4 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.8 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.2 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0060307 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.9 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 0.5 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 1.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 4.8 GO:0030048 actin filament-based movement(GO:0030048)
0.1 1.4 GO:0032506 cytokinetic process(GO:0032506)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.8 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.4 GO:0060420 regulation of heart growth(GO:0060420)
0.1 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.1 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 1.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.4 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.1 0.2 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.1 0.2 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.1 0.5 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 0.3 GO:0045299 otolith mineralization(GO:0045299)
0.1 0.3 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.2 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.1 0.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.4 GO:0060147 regulation of posttranscriptional gene silencing(GO:0060147) regulation of gene silencing by miRNA(GO:0060964) regulation of gene silencing by RNA(GO:0060966)
0.1 0.2 GO:0015867 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.1 2.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.5 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.9 GO:0016203 muscle attachment(GO:0016203)
0.1 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.4 GO:0070586 cell-cell adhesion involved in gastrulation(GO:0070586)
0.1 2.4 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 1.4 GO:0051923 sulfation(GO:0051923)
0.1 0.6 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.2 GO:0051154 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.1 0.6 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 1.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.8 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.2 GO:0090594 inflammatory response to wounding(GO:0090594)
0.0 1.0 GO:0010952 positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.0 0.8 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 1.0 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 4.9 GO:0031101 fin regeneration(GO:0031101)
0.0 1.6 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 1.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.2 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.6 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 1.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0033628 plasminogen activation(GO:0031639) regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 0.8 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 2.0 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.6 GO:0003313 heart rudiment development(GO:0003313)
0.0 0.2 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.0 0.6 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.4 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.6 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.4 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0019320 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) hexose catabolic process(GO:0019320) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.6 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.7 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.8 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.5 GO:0009408 response to heat(GO:0009408)
0.0 1.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0000256 allantoin catabolic process(GO:0000256)
0.0 0.6 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:1902746 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.6 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.4 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.6 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 17.5 GO:0006955 immune response(GO:0006955)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.8 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.5 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 1.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.0 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.5 GO:0050930 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.5 GO:0042574 retinal metabolic process(GO:0042574)
0.0 3.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.7 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043122) negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.5 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.0 0.4 GO:0035108 limb morphogenesis(GO:0035108)
0.0 0.5 GO:0061055 myotome development(GO:0061055)
0.0 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.4 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.6 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.8 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.0 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 2.0 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 11.4 GO:0006412 translation(GO:0006412)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.7 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.3 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.7 GO:0039021 pronephric glomerulus development(GO:0039021)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.5 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.2 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 1.0 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.1 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 1.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.3 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.3 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.2 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.3 GO:0034508 centromere complex assembly(GO:0034508)
0.0 1.7 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.1 GO:0002696 positive regulation of leukocyte activation(GO:0002696)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.0 GO:1903513 retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.0 0.1 GO:0034627 tryptophan catabolic process to kynurenine(GO:0019441) 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.0 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 2.3 GO:0032956 regulation of actin cytoskeleton organization(GO:0032956)
0.0 0.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0030730 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 0.5 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.3 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0043363 nucleate erythrocyte differentiation(GO:0043363) nucleate erythrocyte development(GO:0048823)
0.0 0.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.6 GO:1903052 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052) positive regulation of cellular protein catabolic process(GO:1903364)
0.0 0.1 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 1.2 GO:0001503 ossification(GO:0001503)
0.0 0.4 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.6 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0061702 inflammasome complex(GO:0061702)
0.4 2.1 GO:0097433 dense body(GO:0097433)
0.4 4.7 GO:0045095 keratin filament(GO:0045095)
0.4 1.3 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.4 6.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 1.1 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.3 1.4 GO:0019815 B cell receptor complex(GO:0019815)
0.3 2.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 0.9 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 8.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 1.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 2.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.3 GO:0000796 condensin complex(GO:0000796)
0.2 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.5 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.2 0.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.4 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.1 7.6 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.7 GO:0042611 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0097255 R2TP complex(GO:0097255)
0.1 1.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.3 GO:0015935 small ribosomal subunit(GO:0015935)
0.1 0.7 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 0.5 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.8 GO:0032021 NELF complex(GO:0032021)
0.1 0.3 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0097361 CIA complex(GO:0097361)
0.1 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 4.4 GO:0005902 microvillus(GO:0005902)
0.1 8.9 GO:0005884 actin filament(GO:0005884)
0.1 0.8 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 1.6 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.8 GO:0036038 MKS complex(GO:0036038)
0.1 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 2.1 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 3.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.8 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.9 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 5.6 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 2.9 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 11.1 GO:0005764 lysosome(GO:0005764)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.5 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
0.0 1.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0030055 cell-substrate junction(GO:0030055)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.2 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 3.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.7 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 2.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.0 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.9 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.8 GO:0005840 ribosome(GO:0005840)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 4.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 1.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 12.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0070822 Sin3-type complex(GO:0070822)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.6 2.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 1.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.4 2.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.4 1.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.4 1.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.4 2.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.4 1.1 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.3 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.3 2.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 1.0 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.3 2.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 1.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 1.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 0.8 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.2 1.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.7 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.2 0.6 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 1.4 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.2 2.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 0.8 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 0.6 GO:0045545 syndecan binding(GO:0045545)
0.2 0.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 1.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.5 GO:0047690 aspartyltransferase activity(GO:0047690)
0.2 1.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 1.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 0.8 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.2 0.5 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.2 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 10.2 GO:0008009 chemokine activity(GO:0008009)
0.2 2.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 3.1 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 1.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 0.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 1.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.7 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 1.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 2.1 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.6 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.6 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.9 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.8 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 18.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.1 GO:0030547 receptor inhibitor activity(GO:0030547)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 1.0 GO:0004568 chitinase activity(GO:0004568)
0.1 1.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.1 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.1 1.0 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.3 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.3 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 6.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 0.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 1.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.9 GO:0051117 ATPase binding(GO:0051117)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 1.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.3 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 0.2 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 1.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 19.9 GO:0051015 actin filament binding(GO:0051015)
0.1 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.4 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 2.4 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 5.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 8.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.4 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 1.5 GO:0019956 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.6 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 4.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.6 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 1.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 1.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.9 GO:0099604 ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 3.0 GO:0005125 cytokine activity(GO:0005125)
0.0 0.8 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 3.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 3.3 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.4 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862) protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.1 GO:0015168 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.0 0.0 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.9 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.5 GO:0050661 NADP binding(GO:0050661)
0.0 4.2 GO:0003779 actin binding(GO:0003779)
0.0 0.0 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0008235 metalloexopeptidase activity(GO:0008235) metalloaminopeptidase activity(GO:0070006)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.3 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0045125 sphingosine-1-phosphate receptor activity(GO:0038036) bioactive lipid receptor activity(GO:0045125)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 1.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 4.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 1.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.3 PID EPO PATHWAY EPO signaling pathway
0.1 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 5.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 0.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 3.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 3.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 5.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 3.1 PID AURORA B PATHWAY Aurora B signaling
0.1 0.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.1 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.6 PID AP1 PATHWAY AP-1 transcription factor network
0.1 0.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.2 PID E2F PATHWAY E2F transcription factor network
0.0 1.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.4 1.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 2.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 1.6 REACTOME OPSINS Genes involved in Opsins
0.3 3.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 2.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 0.7 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.2 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 10.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 1.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 1.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 1.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.9 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 7.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.6 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 1.3 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 4.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.5 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 3.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 2.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 5.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 2.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.7 REACTOME TRANSLATION Genes involved in Translation
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA