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PRJNA207719: Tissue specific transcriptome profiling

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Results for tbx20

Z-value: 0.63

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Transcription factors associated with tbx20

Gene Symbol Gene ID Gene Info
tbx20
ENSDARG00000005150 T-box transcription factor 20

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbx20dr11_v1_chr16_-_42523744_42523744-0.158.1e-01Click!

Activity profile of tbx20 motif

Sorted Z-values of tbx20 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_32228538 1.04 ENSDART00000077471
myhc4
myosin heavy chain 4
chr9_+_23900703 0.77 ENSDART00000127859
trim63b
tripartite motif containing 63b
chr7_+_39389273 0.56 ENSDART00000191298
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr7_-_69853453 0.53 ENSDART00000049928
myoz2a
myozenin 2a
chr8_-_11112058 0.53 ENSDART00000042755
ampd1
adenosine monophosphate deaminase 1 (isoform M)
chr13_-_293250 0.50 ENSDART00000138581
chs1
chitin synthase 1
chr1_-_462165 0.49 ENSDART00000152799
si:ch73-244f7.3
si:ch73-244f7.3
chr12_+_48340133 0.30 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr2_-_51109476 0.25 ENSDART00000168286
si:ch73-52e5.1
si:ch73-52e5.1
chr24_+_13869092 0.24 ENSDART00000176492
eya1
EYA transcriptional coactivator and phosphatase 1
chr20_+_826459 0.23 ENSDART00000104740
nt5e
5'-nucleotidase, ecto (CD73)
chr11_+_45233348 0.19 ENSDART00000173150
tmc6b
transmembrane channel-like 6b
chr22_+_20710434 0.15 ENSDART00000135521
peak3
PEAK family member 3
chr7_+_40081630 0.14 ENSDART00000173559
zgc:112356
zgc:112356
chr25_+_18475032 0.14 ENSDART00000073564
tes
testis derived transcript (3 LIM domains)
chr15_-_47479119 0.14 ENSDART00000164957
inppl1a
inositol polyphosphate phosphatase-like 1a
chr7_-_40082053 0.12 ENSDART00000083719
ENSDART00000173687
shrprbck1r
sharpin and rbck1 related
chr21_+_30351256 0.12 ENSDART00000078341
foxi3a
forkhead box I3a
chr15_+_31515976 0.11 ENSDART00000156471
tex26
testis expressed 26
chr23_-_27479558 0.10 ENSDART00000013563
atf7a
activating transcription factor 7a
chr17_+_26965351 0.09 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr1_-_59360114 0.09 ENSDART00000160445
CABZ01052573.1

chr15_+_43799258 0.09 ENSDART00000122238
tyr
tyrosinase
chr7_+_756942 0.09 ENSDART00000152224
zgc:63470
zgc:63470
chr3_-_33417826 0.08 ENSDART00000084284
abi3a
ABI family, member 3a
chr8_+_36416285 0.08 ENSDART00000158400
si:busm1-194e12.8
si:busm1-194e12.8
chr10_+_11355841 0.07 ENSDART00000193067
ENSDART00000064215
cops4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr5_-_36549024 0.07 ENSDART00000097671
zgc:158432
zgc:158432
chr3_+_52475058 0.07 ENSDART00000035867
si:ch211-241f5.3
si:ch211-241f5.3
chr1_-_58913813 0.07 ENSDART00000056494
zgc:171687
zgc:171687
chr12_+_4920451 0.07 ENSDART00000171525
ENSDART00000159986
plekhm1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr11_-_12104917 0.06 ENSDART00000136108
mrpl45
mitochondrial ribosomal protein L45
chr15_-_41689684 0.06 ENSDART00000143447
spsb4b
splA/ryanodine receptor domain and SOCS box containing 4b
chr5_+_12515402 0.06 ENSDART00000103278
zgc:171242
zgc:171242
chr5_-_49012569 0.06 ENSDART00000184690
si:dkey-172m14.2
si:dkey-172m14.2
chr12_-_43664682 0.05 ENSDART00000159423
foxi1
forkhead box i1
chr15_+_33696559 0.05 ENSDART00000188248
ENSDART00000161951
hdac12
histone deacetylase 12
chr7_+_6879534 0.05 ENSDART00000157731
zgc:175248
zgc:175248
chr5_-_44843738 0.05 ENSDART00000003926
fbp1a
fructose-1,6-bisphosphatase 1a
chr2_-_57076687 0.04 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr25_-_7686201 0.04 ENSDART00000157267
ENSDART00000155094
si:ch211-286c4.6
si:ch211-286c4.6
chr7_-_5070794 0.04 ENSDART00000097877
ltb4r2a
leukotriene B4 receptor 2a
chr25_+_19170500 0.04 ENSDART00000182572
BX294110.2

chr4_-_50207986 0.04 ENSDART00000150388
si:ch211-197e7.3
si:ch211-197e7.3
chr15_-_31516558 0.04 ENSDART00000156427
ENSDART00000156072
ENSDART00000156047
hmgb1b
high mobility group box 1b
chr2_-_16216568 0.04 ENSDART00000173758
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr4_+_35138928 0.04 ENSDART00000167934
ENSDART00000192116
ENSDART00000183689
si:dkey-279j5.1
si:dkey-279j5.1
chr14_+_80685 0.03 ENSDART00000188443
stag3
stromal antigen 3
chr7_+_69449814 0.03 ENSDART00000109644
ctdnep1b
CTD nuclear envelope phosphatase 1b
chr4_+_59234719 0.03 ENSDART00000170724
ENSDART00000192143
ENSDART00000109914
znf1086
zinc finger protein 1086
chr3_-_8285123 0.03 ENSDART00000158699
ENSDART00000138588
trim35-9
tripartite motif containing 35-9
chr8_+_30747940 0.03 ENSDART00000098975
p2rx4b
purinergic receptor P2X, ligand-gated ion channel, 4b
chr22_-_35385810 0.03 ENSDART00000111824
HTR3C
5-hydroxytryptamine receptor 3C
chr11_-_44622478 0.03 ENSDART00000171837
tbce
tubulin folding cofactor E
chr11_-_44622240 0.03 ENSDART00000172258
ENSDART00000173340
tbce
tubulin folding cofactor E
chr7_+_48675347 0.03 ENSDART00000157917
ENSDART00000185580
trpm5
transient receptor potential cation channel, subfamily M, member 5
chr3_-_7940522 0.03 ENSDART00000159710
ENSDART00000167201
trim35-25
tripartite motif containing 35-25
chr3_-_5555500 0.03 ENSDART00000176133
ENSDART00000057464
trim35-31
tripartite motif containing 35-31
chr24_+_26742226 0.03 ENSDART00000079721
ghsrb
growth hormone secretagogue receptor b
chr25_+_37285737 0.02 ENSDART00000126879
tmed6
transmembrane p24 trafficking protein 6
chr11_+_44622472 0.02 ENSDART00000159068
ENSDART00000166323
ENSDART00000187753
rbm34
RNA binding motif protein 34
chr25_-_35107791 0.02 ENSDART00000192819
zgc:165555
zgc:165555
chr21_+_5494561 0.02 ENSDART00000169728
ly6m3
lymphocyte antigen 6 family member M3
chr15_+_44208464 0.02 ENSDART00000126868
CU929391.1

chr12_+_19362547 0.02 ENSDART00000180148
gspt1
G1 to S phase transition 1
chr3_-_5964557 0.02 ENSDART00000184738
BX284638.1

chr4_+_59320243 0.02 ENSDART00000150611
znf1084
zinc finger protein 1084
chr20_+_15600167 0.01 ENSDART00000171991
faslg
Fas ligand (TNF superfamily, member 6)
chr4_-_75812937 0.01 ENSDART00000125096
si:ch211-203c5.3
si:ch211-203c5.3
chr4_+_38103421 0.01 ENSDART00000164164
znf1016
zinc finger protein 1016
chr4_+_32156734 0.01 ENSDART00000163904
CR450785.1

chr20_-_116999 0.00 ENSDART00000149581
ypel5
yippee-like 5
chr14_+_20911310 0.00 ENSDART00000160318
lygl2
lysozyme g-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx20

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.5 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0006585 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.0 0.2 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.5 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.0 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.6 GO:0003009 skeletal muscle contraction(GO:0003009)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030428 cell septum(GO:0030428)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.6 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.5 GO:0004100 chitin synthase activity(GO:0004100)
0.1 0.5 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.0 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism