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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Foxf2

Z-value: 0.51

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Transcription factors associated with Foxf2

Gene Symbol Gene ID Gene Info

Activity profile of Foxf2 motif

Sorted Z-values of Foxf2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_71849293 0.57 ENSRNOT00000003799
LIM homeobox 1
chr7_+_28654733 0.49 ENSRNOT00000006174
pro-melanin-concentrating hormone
chr7_+_120580743 0.40 ENSRNOT00000017181
MAF bZIP transcription factor F
chr10_-_90307658 0.39 ENSRNOT00000092102
solute carrier family 4 member 1
chr16_-_20807070 0.37 ENSRNOT00000072536
cartilage oligomeric matrix protein
chr1_-_215536980 0.27 ENSRNOT00000027344
interferon induced transmembrane protein 10
chr4_+_152630469 0.20 ENSRNOT00000013721
ninjurin 2
chr10_+_103395511 0.20 ENSRNOT00000004256
G protein-coupled receptor, class C, group 5, member C
chr7_-_107775712 0.18 ENSRNOT00000010811
ENSRNOT00000093459
N-myc downstream regulated 1
chr8_+_94686938 0.17 ENSRNOT00000013285
ripply transcriptional repressor 2
chr10_+_56662242 0.17 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr3_+_149624712 0.15 ENSRNOT00000018581
BPI fold containing family A, member 1
chr1_-_156327352 0.14 ENSRNOT00000074282
coiled-coil domain-containing protein 89-like
chr1_-_20417637 0.14 ENSRNOT00000036049
similar to High mobility group protein 2 (HMG-2)
chr4_+_57855416 0.13 ENSRNOT00000029608
carboxypeptidase A2
chr1_+_154606490 0.13 ENSRNOT00000024095
coiled-coil domain containing 89
chr4_-_176528110 0.11 ENSRNOT00000049569
solute carrier organic anion transporter family, member 1A2
chr8_+_99568958 0.10 ENSRNOT00000073400
phospholipid scramblase family, member 5
chr2_-_123972356 0.10 ENSRNOT00000023348
interleukin 21
chr6_-_44363915 0.09 ENSRNOT00000085925
inhibitor of DNA binding 2, HLH protein
chr1_+_274049533 0.08 ENSRNOT00000076779
ENSRNOT00000042822
MAX interactor 1, dimerization protein
chr18_+_68408890 0.08 ENSRNOT00000039702
coiled-coil domain containing 68
chr20_+_46429222 0.08 ENSRNOT00000076818
forkhead box O3
chr2_-_3124543 0.08 ENSRNOT00000036547
family with sequence similarity 81, member B
chr1_-_214455039 0.07 ENSRNOT00000071028
RNA polymerase II subunit L
chr3_-_60023913 0.07 ENSRNOT00000064662
corepressor interacting with RBPJ, 1
chr3_-_168018410 0.06 ENSRNOT00000087579
breast carcinoma amplified sequence 1
chr13_-_80862963 0.06 ENSRNOT00000004864
flavin containing monooxygenase 3
chr10_+_72909550 0.06 ENSRNOT00000004540
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr4_+_71512695 0.06 ENSRNOT00000037220
taste receptor, type 2, member 139
chr14_+_42714315 0.05 ENSRNOT00000084095
ENSRNOT00000091449
paired-like homeobox 2b
chr5_+_164923302 0.05 ENSRNOT00000042285
60S ribosomal protein L35a
chr6_-_77421286 0.05 ENSRNOT00000011453
NK2 homeobox 1
chr2_+_157316266 0.04 ENSRNOT00000015387
TCDD-inducible poly(ADP-ribose) polymerase
chr2_+_200603426 0.04 ENSRNOT00000072189
zinc finger protein 697-like
chr20_+_29655226 0.04 ENSRNOT00000089059
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2
chr20_-_11721838 0.04 ENSRNOT00000001636
ubiquitin-conjugating enzyme E2G 2
chr2_-_100249811 0.04 ENSRNOT00000086760
hepatocyte nuclear factor 4, gamma
chr4_-_183426439 0.04 ENSRNOT00000083310
family with sequence similarity 60, member A
chr6_-_137084739 0.03 ENSRNOT00000060943
transmembrane protein 179
chr1_-_101773508 0.03 ENSRNOT00000067430
sulfotransferase family 2B member 1
chr1_-_102970950 0.03 ENSRNOT00000018194
tumor susceptibility 101
chr6_+_137243185 0.03 ENSRNOT00000030879
zinc finger and BTB domain containing 42
chr5_+_64282351 0.03 ENSRNOT00000011273
Myb/SANT DNA binding domain containing 3
chr4_+_153921115 0.03 ENSRNOT00000018821
solute carrier family 6 member 12
chr16_-_19583386 0.03 ENSRNOT00000090131
zinc finger protein 617
chr13_-_97838228 0.03 ENSRNOT00000003618
transcription factor B2, mitochondrial
chr15_-_28313841 0.03 ENSRNOT00000085897
NDRG family member 2
chr14_-_8432195 0.03 ENSRNOT00000089800
Rho GTPase activating protein 24
chr1_-_206282575 0.03 ENSRNOT00000024974
ADAM metallopeptidase domain 12
chr3_-_101474890 0.02 ENSRNOT00000091869
gamma-butyrobetaine hydroxylase 1
chr4_+_14071507 0.02 ENSRNOT00000066224
ENSRNOT00000075962
CD36 molecule
similar to fatty acid translocase/CD36
chr1_+_264741911 0.02 ENSRNOT00000019956
semaphorin 4G
chr10_-_56849255 0.02 ENSRNOT00000025491
similar to RIKEN cDNA 1110020A23
chr3_-_72219246 0.02 ENSRNOT00000009903
smoothelin-like 1
chr1_-_90978907 0.02 ENSRNOT00000072819
CAP-GLY domain containing linker protein 3
chr14_-_3351553 0.02 ENSRNOT00000061556
BTB (POZ) domain containing 8
chr17_-_15478343 0.02 ENSRNOT00000078029
osteomodulin
chr12_-_13998172 0.02 ENSRNOT00000001476
WD repeat domain, phosphoinositide interacting 2
chrX_+_83926513 0.02 ENSRNOT00000035274
similar to RIKEN cDNA 2010106E10
chr1_-_99135977 0.02 ENSRNOT00000056515
vomeronasal 2 receptor, 38
chr8_-_78233430 0.02 ENSRNOT00000083220
cingulin-like 1
chr17_-_45746753 0.02 ENSRNOT00000077475
similar to brain Zn-finger protein
chr8_+_5522739 0.02 ENSRNOT00000011507
matrix metallopeptidase 13
chr3_-_160038078 0.01 ENSRNOT00000013445
serine incorporator 3
chr5_-_173484986 0.01 ENSRNOT00000064207
ENSRNOT00000055319
tubulin tyrosine ligase like 10
chr6_+_91595823 0.01 ENSRNOT00000006223
kelch domain containing 2
chr18_+_13386133 0.01 ENSRNOT00000020661
additional sex combs like 3, transcriptional regulator
chr13_+_53351717 0.01 ENSRNOT00000012038
kinesin family member 14
chr5_-_101006375 0.01 ENSRNOT00000014008
cerberus 1, DAN family BMP antagonist
chr7_-_57816621 0.01 ENSRNOT00000090748

chr7_+_93975451 0.01 ENSRNOT00000011379
collectin subfamily member 10
chr7_+_74047814 0.01 ENSRNOT00000014879
odd-skipped related transciption factor 2
chr1_-_100845392 0.01 ENSRNOT00000027436
TBC1 domain family, member 17
chr14_+_37116492 0.00 ENSRNOT00000002921
sarcoglycan, beta
chr15_+_32894938 0.00 ENSRNOT00000012837
abhydrolase domain containing 4
chr1_+_100845563 0.00 ENSRNOT00000027478
AKT1 substrate 1
chr10_-_56850085 0.00 ENSRNOT00000025767
ribonuclease K
chr2_-_182035032 0.00 ENSRNOT00000009813
fibrinogen beta chain
chr3_-_173944396 0.00 ENSRNOT00000079019
synaptonemal complex protein 2
chr3_+_126335863 0.00 ENSRNOT00000028904
bone morphogenetic protein 2
chr5_+_124300477 0.00 ENSRNOT00000010100
complement C8 beta chain

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxf2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0060066 metanephric part of ureteric bud development(GO:0035502) oviduct development(GO:0060066)
0.1 0.5 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.4 GO:0010037 response to carbon dioxide(GO:0010037)
0.1 0.2 GO:0050828 regulation of liquid surface tension(GO:0050828)
0.0 0.1 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.1 GO:0048880 medulla oblongata development(GO:0021550) sensory system development(GO:0048880)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.4 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.0 GO:0050294 steroid sulfotransferase activity(GO:0050294)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts