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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxa1

Z-value: 0.40

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Transcription factors associated with Hoxa1

Gene Symbol Gene ID Gene Info
ENSRNOG00000005628 homeo box A1

Activity profile of Hoxa1 motif

Sorted Z-values of Hoxa1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_96131880 0.32 ENSRNOT00000004578
calcium voltage-gated channel auxiliary subunit gamma 5
chr5_-_155381732 0.17 ENSRNOT00000033670
zinc finger and BTB domain containing 40
chr7_+_70753101 0.16 ENSRNOT00000090001
R3H domain containing 2
chr1_-_260992291 0.16 ENSRNOT00000035415
ENSRNOT00000034758
slit guidance ligand 1
chr12_+_13810180 0.15 ENSRNOT00000084865
ENSRNOT00000038203
trinucleotide repeat containing 18
chr3_+_154863072 0.15 ENSRNOT00000055200
small nucleolar RNA host gene 11
chr16_+_46731403 0.13 ENSRNOT00000017624
teneurin transmembrane protein 3
chr1_-_267245636 0.13 ENSRNOT00000082799
SH3 and PX domains 2A
chr8_+_127171537 0.12 ENSRNOT00000078625
ENSRNOT00000051290
ENSRNOT00000087753
golgin A4
chr15_+_51756978 0.12 ENSRNOT00000024067
early growth response 3
chr3_-_133122691 0.11 ENSRNOT00000083637
taspase 1
chr9_-_52238564 0.11 ENSRNOT00000005073
collagen type V alpha 2 chain
chr13_+_46169963 0.11 ENSRNOT00000005212
thrombospondin type 1 domain containing 7B
chr9_+_118849302 0.11 ENSRNOT00000087592
DLG associated protein 1
chr3_-_158328881 0.09 ENSRNOT00000044466
protein tyrosine phosphatase, receptor type, T
chr7_+_124680294 0.09 ENSRNOT00000014720
metallophosphoesterase domain containing 1
chr13_+_50974872 0.09 ENSRNOT00000080768
chitinase 1
chr19_-_50220455 0.08 ENSRNOT00000079760
short chain dehydrogenase/reductase family 42E, member 1
chr9_-_88256115 0.07 ENSRNOT00000076472
collagen type IV alpha 4 chain
chr15_+_41448064 0.07 ENSRNOT00000019551
sacsin molecular chaperone
chr17_-_66397653 0.07 ENSRNOT00000024098
actinin alpha 2
chr16_-_62241361 0.07 ENSRNOT00000090036
glutathione-disulfide reductase
chr10_+_42614713 0.06 ENSRNOT00000081136
ENSRNOT00000073148
glutamate ionotropic receptor AMPA type subunit 1
chrX_+_82143789 0.06 ENSRNOT00000003724
POU class 3 homeobox 4
chr8_+_82257849 0.06 ENSRNOT00000011963
ENSRNOT00000075708
G protein subunit beta 5
chr4_-_155275161 0.06 ENSRNOT00000032690
ribosomal modification protein rimK-like family member B
chr7_+_123482255 0.06 ENSRNOT00000064487
hypothetical protein LOC688613
chr17_+_4846789 0.06 ENSRNOT00000073271
growth arrest-specific 1
chr1_-_222350173 0.05 ENSRNOT00000030625
fibronectin leucine rich transmembrane protein 1
chr6_+_26566494 0.05 ENSRNOT00000079292
general transcription factor IIIC subunit 2
chr10_-_14443010 0.05 ENSRNOT00000022142
transmembrane protein 204
chr20_-_31956649 0.05 ENSRNOT00000072429
hexokinase 1
chr12_-_37682964 0.05 ENSRNOT00000001421
similar to hypothetical protein FLJ38663
chr12_+_13323547 0.05 ENSRNOT00000074138
zinc finger protein 853
chr19_+_55206455 0.05 ENSRNOT00000039273
zinc finger CCCH-type containing 18
chr7_-_122963299 0.05 ENSRNOT00000090208
RAN GTPase activating protein 1
chr5_+_124021366 0.05 ENSRNOT00000009977
DAB1, reelin adaptor protein
chr2_+_164747677 0.04 ENSRNOT00000018489
major facilitator superfamily domain containing 1
chr12_+_49419582 0.04 ENSRNOT00000082998
similar to hypothetical protein A530094D01
chr5_-_126395668 0.04 ENSRNOT00000010396
acyl-CoA thioesterase 11
chr19_+_24545318 0.04 ENSRNOT00000005071
calmegin
chr15_-_88036354 0.04 ENSRNOT00000014747
endothelin receptor type B
chr1_-_127292090 0.03 ENSRNOT00000016959
leucine-rich repeat kinase 1
chr10_-_95062987 0.02 ENSRNOT00000019781
SMAD specific E3 ubiquitin protein ligase 2
chr1_-_7443863 0.02 ENSRNOT00000088558
phosphatase and actin regulator 2
chr13_+_77485113 0.02 ENSRNOT00000080254
tenascin R
chr13_+_84474319 0.02 ENSRNOT00000031367
ENSRNOT00000072244
ENSRNOT00000072897
ENSRNOT00000064168
ENSRNOT00000074954
ENSRNOT00000073696
immunoglobulin-like domain containing receptor 2
chr13_+_71107465 0.02 ENSRNOT00000003239
regulator of G-protein signaling 8
chr2_+_3662763 0.02 ENSRNOT00000017828
multiple C2 and transmembrane domain containing 1
chr8_-_2045817 0.02 ENSRNOT00000009542
ENSRNOT00000081171
ENSRNOT00000078765
glutamate ionotropic receptor AMPA type subunit 4
chr10_+_67427066 0.02 ENSRNOT00000035642
ATPase family, AAA domain containing 5
chr5_-_7941822 0.01 ENSRNOT00000079917
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr12_+_11179329 0.01 ENSRNOT00000001302
zinc finger protein 394
chr14_+_3506339 0.01 ENSRNOT00000002867
transforming growth factor beta receptor 3
chr10_-_87153982 0.01 ENSRNOT00000014414
keratin 222
chr6_+_145546595 0.01 ENSRNOT00000007112
Rap guanine nucleotide exchange factor 5
chr12_+_17277635 0.01 ENSRNOT00000001734
hypothetical protein LOC498154
chr4_-_4473307 0.01 ENSRNOT00000045773
dipeptidyl peptidase like 6
chr11_-_64421248 0.01 ENSRNOT00000066997
immunoglobulin superfamily, member 11
chr4_-_184096806 0.00 ENSRNOT00000055433
mKIAA1238 protein-like
chr10_-_65507581 0.00 ENSRNOT00000016759
SPT6 homolog, histone chaperone
chr11_-_25078740 0.00 ENSRNOT00000002109
cysteine and tyrosine rich 1
chr20_-_6556350 0.00 ENSRNOT00000035819
LEM domain containing 2
chrX_-_104984341 0.00 ENSRNOT00000077996
XK related, X-linked
chr15_-_18675431 0.00 ENSRNOT00000080794
abhydrolase domain containing 6
chr17_-_55346279 0.00 ENSRNOT00000025037
supervillin
chr16_+_24980723 0.00 ENSRNOT00000082142
translation machinery associated 16 homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0051695 actin filament uncapping(GO:0051695) positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)