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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Hoxb13

Z-value: 0.62

Motif logo

Transcription factors associated with Hoxb13

Gene Symbol Gene ID Gene Info
ENSRNOG00000007491 homeo box B13

Activity profile of Hoxb13 motif

Sorted Z-values of Hoxb13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_21473808 0.52 ENSRNOT00000066776
zinc finger protein 964
chr1_-_66212418 0.45 ENSRNOT00000026074
hypothetical protein LOC691722
chr6_-_76552559 0.34 ENSRNOT00000065230
Ral GTPase activating protein catalytic alpha subunit 1
chr7_-_101138860 0.31 ENSRNOT00000077137

chr4_-_155740193 0.27 ENSRNOT00000043229
LRRGT00188
chr2_+_148262110 0.26 ENSRNOT00000046641

chr19_-_21970103 0.26 ENSRNOT00000074210

chrX_+_137934484 0.24 ENSRNOT00000049046
hypothetical protein LOC317588
chr4_+_22859622 0.24 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr2_-_86475096 0.23 ENSRNOT00000075247
ENSRNOT00000075062
zinc finger protein 43-like
chr1_+_61522298 0.22 ENSRNOT00000029111
zinc finger protein 51
chr13_+_91054974 0.22 ENSRNOT00000091089
C-reactive protein
chr13_+_41802697 0.21 ENSRNOT00000046719
LRRGT00155-like
chr9_-_88816898 0.21 ENSRNOT00000083667
solute carrier family 19 member 3
chrM_+_11736 0.21 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr2_+_23289374 0.20 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr8_-_13906355 0.20 ENSRNOT00000029634
centrosomal protein 295
chrX_-_10031167 0.20 ENSRNOT00000060988
G protein-coupled receptor 34
chr8_-_124399494 0.19 ENSRNOT00000037883
transforming growth factor, beta receptor 2
chr1_-_66237501 0.18 ENSRNOT00000073006
zinc finger protein 606
chr15_-_93765498 0.18 ENSRNOT00000093297
MYC binding protein 2, E3 ubiquitin protein ligase
chr16_+_22361998 0.18 ENSRNOT00000016193
solute carrier family 18 member A1
chr6_+_93563446 0.18 ENSRNOT00000050558
ENSRNOT00000011056
similar to Protein KIAA0586
chr9_+_73529612 0.18 ENSRNOT00000032430
unc-80 homolog, NALCN activator
chr17_-_80860195 0.18 ENSRNOT00000038651
tRNA aspartic acid methyltransferase 1
chr12_-_5773036 0.17 ENSRNOT00000041365
FRY microtubule binding protein
chr20_-_31598118 0.17 ENSRNOT00000046537
collagen type XIII alpha 1 chain
chr18_+_1723565 0.17 ENSRNOT00000033468
growth regulation by estrogen in breast cancer 1 like
chr3_+_155269347 0.17 ENSRNOT00000021308
family with sequence similarity 83, member D
chr12_-_35979193 0.16 ENSRNOT00000071104
transmembrane protein 132B
chr2_-_149444548 0.16 ENSRNOT00000018600
purinergic receptor P2Y12
chr18_+_30487264 0.16 ENSRNOT00000040125
protocadherin beta 10
chr3_-_55951584 0.16 ENSRNOT00000036585
FAST kinase domains 1
chr6_-_98666007 0.16 ENSRNOT00000082695

chr8_-_123829749 0.15 ENSRNOT00000090467

chr16_+_85331866 0.15 ENSRNOT00000019615
DNA ligase 4
chr16_-_14360555 0.15 ENSRNOT00000065460
hypothetical gene supported by AF152002
chrX_+_120901495 0.15 ENSRNOT00000040742
WD repeat domain 44
chr4_+_88694583 0.15 ENSRNOT00000009202
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr15_-_30147793 0.15 ENSRNOT00000060399

chr9_-_7891514 0.15 ENSRNOT00000072684
protection of telomeres 1B
chr1_-_250626844 0.15 ENSRNOT00000077135
N-acylsphingosine amidohydrolase 2
chr6_+_27887797 0.15 ENSRNOT00000015827
additional sex combs like 2, transcriptional regulator
chr5_+_90818736 0.15 ENSRNOT00000093480
ENSRNOT00000009083
lysine demethylase 4C
chrX_+_43183381 0.14 ENSRNOT00000039874
melanoma antigen, family A, 8
chr6_+_64224861 0.14 ENSRNOT00000093159
ENSRNOT00000093664
patatin-like phospholipase domain containing 8
chr1_-_31881531 0.14 ENSRNOT00000081225
tubulin polymerization promoting protein
chr1_-_88516129 0.14 ENSRNOT00000087232

chr10_+_57239993 0.14 ENSRNOT00000067919
hypothetical protein LOC687707
chr6_-_95502775 0.14 ENSRNOT00000074990
ENSRNOT00000034289
dehydrogenase/reductase (SDR family) member 7-like 1
chr7_+_2435553 0.14 ENSRNOT00000065593
primase (DNA) subunit 1
chr3_-_61488696 0.14 ENSRNOT00000083045
lunapark, ER junction formation factor
chr17_-_44643362 0.13 ENSRNOT00000091041
zinc finger protein 184
chr8_-_46750898 0.13 ENSRNOT00000059951
tubulin folding cofactor E-like
chr7_+_141642777 0.13 ENSRNOT00000079811

chr4_-_89281222 0.13 ENSRNOT00000010898
family with sequence similarity 13, member A
chr16_+_31734944 0.13 ENSRNOT00000059673
palladin, cytoskeletal associated protein
chr2_+_211740637 0.13 ENSRNOT00000066924
HEN1 methyltransferase homolog 1
chr2_+_52152536 0.13 ENSRNOT00000072691

chr1_+_226573105 0.13 ENSRNOT00000028074
cleavage and polyadenylation specific factor 7
chr5_-_168120179 0.13 ENSRNOT00000093063
period circadian clock 3
chr15_-_39742103 0.13 ENSRNOT00000074587
ENSRNOT00000036781
ENSRNOT00000071919
SET domain, bifurcated 2
chrX_-_71313513 0.13 ENSRNOT00000004972
ENSRNOT00000076008
ENSRNOT00000076042
zinc finger MYM-type containing 3
chr2_+_189714754 0.13 ENSRNOT00000086285
GATA zinc finger domain containing 2B
chr17_-_11916026 0.13 ENSRNOT00000046385
similar to RIKEN cDNA 2900010M23
chr18_-_75207306 0.12 ENSRNOT00000021717
SET binding protein 1
chr15_-_76789298 0.12 ENSRNOT00000077853

chr1_+_27924825 0.12 ENSRNOT00000087830

chr1_-_69835185 0.12 ENSRNOT00000020757
spindle assembly abnormal protein 6 homolog
chr2_-_220838905 0.12 ENSRNOT00000078914

chr14_-_108658371 0.12 ENSRNOT00000008919
poly(A) polymerase gamma
chr15_-_23606634 0.12 ENSRNOT00000075602
glia maturation factor, beta
chr10_+_54155876 0.12 ENSRNOT00000072855
growth arrest specific 7
chr3_-_40477754 0.12 ENSRNOT00000091168

chr1_+_45923222 0.11 ENSRNOT00000092976
ENSRNOT00000084454
ENSRNOT00000022939
AT-rich interaction domain 1B
chr14_-_8600512 0.11 ENSRNOT00000092537
Rho GTPase activating protein 24
chr2_-_244335165 0.11 ENSRNOT00000084860
Rap1 GTPase-GDP dissociation stimulator 1
chr17_+_70262363 0.11 ENSRNOT00000048933
family with sequence similarity 208, member B
chr9_-_95143092 0.11 ENSRNOT00000064171
ENSRNOT00000085325
ubiquitin specific peptidase 40
chr16_-_7928518 0.11 ENSRNOT00000026680
ankyrin repeat domain 28
chr7_+_122818975 0.11 ENSRNOT00000000206
E1A binding protein p300
chr3_+_60026747 0.11 ENSRNOT00000081881
secernin 3
chr1_+_11963836 0.11 ENSRNOT00000074325

chr9_+_66888393 0.11 ENSRNOT00000023536
calcium responsive transcription factor
chr5_+_135574172 0.11 ENSRNOT00000023416
testis-specific kinase 2
chr1_-_163554839 0.11 ENSRNOT00000081509
EMSY BRCA2-interacting transcriptional repressor
chr6_+_99356509 0.11 ENSRNOT00000008416
A-kinase anchoring protein 5
chr14_+_1355004 0.11 ENSRNOT00000043131

chr4_+_179481263 0.11 ENSRNOT00000021284
electron transfer flavoprotein regulatory factor 1
chr12_-_38093050 0.11 ENSRNOT00000057814
coiled-coil domain containing 62
chr2_-_257546799 0.11 ENSRNOT00000089370
ENSRNOT00000090367
mitoguardin 1
chr18_+_63599425 0.11 ENSRNOT00000023145
centrosomal protein 192
chr1_-_62558033 0.10 ENSRNOT00000015520
zinc finger protein 40
chr11_-_67702955 0.10 ENSRNOT00000084540
ENSRNOT00000078285
karyopherin subunit alpha 1
chr10_+_65552897 0.10 ENSRNOT00000056217
sperm associated antigen 5
chr18_+_38847632 0.10 ENSRNOT00000014916
ELMO domain-containing protein 2-like
chr1_-_37741709 0.10 ENSRNOT00000079186
FAST kinase domains 3
chr2_+_127489771 0.10 ENSRNOT00000093581
inturned planar cell polarity protein
chr9_+_50966766 0.10 ENSRNOT00000076636
ERCC excision repair 5, endonuclease
chr9_-_52238564 0.10 ENSRNOT00000005073
collagen type V alpha 2 chain
chr7_+_132378273 0.10 ENSRNOT00000010990
hypothetical protein LOC690142
chr3_+_56125924 0.10 ENSRNOT00000011380
ubiquitin protein ligase E3 component n-recognin 3
chr2_-_34313094 0.10 ENSRNOT00000016863
peptidylprolyl isomerase domain and WD repeat containing 1
chr14_+_79205466 0.10 ENSRNOT00000085534
TBC1 domain family, member 14
chr8_+_23398030 0.10 ENSRNOT00000031893
similar to RIKEN cDNA 9530077C05
chr15_+_8739589 0.10 ENSRNOT00000071751
nuclear receptor subfamily 1, group D, member 2
chr14_+_70164650 0.10 ENSRNOT00000004385
quinoid dihydropteridine reductase
chr7_-_47586137 0.10 ENSRNOT00000006086
transmembrane and tetratricopeptide repeat containing 2
chr9_-_69878706 0.10 ENSRNOT00000035879
INO80 complex subunit D
chr5_-_140024176 0.10 ENSRNOT00000016492
transmembrane and coiled-coil domains 2
chr7_+_74350479 0.10 ENSRNOT00000089034

chr6_-_76608864 0.10 ENSRNOT00000010824
Ral GTPase activating protein catalytic alpha subunit 1
chr2_+_196608496 0.10 ENSRNOT00000091681
aryl hydrocarbon receptor nuclear translocator
chr1_+_214927172 0.10 ENSRNOT00000027134
BR serine/threonine kinase 2
chr17_-_78812111 0.10 ENSRNOT00000021506
DNA cross-link repair 1C
chr8_-_69466618 0.10 ENSRNOT00000042925
iduronate 2-sulfatase
chr18_+_17403407 0.10 ENSRNOT00000045150
similar to KIAA1328 protein
chr10_+_106712127 0.10 ENSRNOT00000040629
trinucleotide repeat containing 6C
chr7_+_15785410 0.10 ENSRNOT00000082664
ENSRNOT00000073235
zinc finger protein 955A
chr6_+_135513650 0.10 ENSRNOT00000010676
REST corepressor 1
chr1_+_42169501 0.10 ENSRNOT00000025477
ENSRNOT00000092791
vasoactive intestinal peptide
chr9_+_73378057 0.10 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr10_-_55997299 0.10 ENSRNOT00000074505
cytochrome b5 domain containing 1
chr17_+_76532611 0.10 ENSRNOT00000024099
calcium/calmodulin-dependent protein kinase ID
chr6_+_30074303 0.10 ENSRNOT00000070908
family with sequence similarity 228, member A
chrX_-_111325186 0.10 ENSRNOT00000086785
RNA binding motif protein 41
chr13_-_82295123 0.10 ENSRNOT00000090120
similar to hypothetical protein FLJ10706
chr5_+_4373626 0.10 ENSRNOT00000064946
EYA transcriptional coactivator and phosphatase 1
chr9_-_120101098 0.09 ENSRNOT00000002917
family with sequence similarity 114, member A1-like 1
chrY_-_1238420 0.09 ENSRNOT00000092078
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3
chr17_+_45078556 0.09 ENSRNOT00000088280
zinc finger protein 192
chr3_-_120157866 0.09 ENSRNOT00000020367
zinc finger protein 2-like
chr9_+_50892605 0.09 ENSRNOT00000033133
basic, immunoglobulin-like variable motif containing
chr8_-_96547568 0.09 ENSRNOT00000078343
similar to RIKEN cDNA 4930579C12 gene
chr9_-_112027155 0.09 ENSRNOT00000021258
ENSRNOT00000080962
praja ring finger ubiquitin ligase 2
chr10_+_15196130 0.09 ENSRNOT00000082567
jumonji domain containing 8
chr9_-_65442257 0.09 ENSRNOT00000037660
family with sequence similarity 126, member B
chr2_+_56052643 0.09 ENSRNOT00000029565
RPTOR independent companion of MTOR, complex 2
chr3_+_113918629 0.09 ENSRNOT00000078978
ENSRNOT00000037168
CTD small phosphatase like 2
chr15_+_41937880 0.09 ENSRNOT00000032514
potassium channel regulator
chr8_-_49158971 0.09 ENSRNOT00000020573
lysine methyltransferase 2A
chr8_+_49418965 0.09 ENSRNOT00000021819
sodium voltage-gated channel beta subunit 2
chr2_-_27287605 0.09 ENSRNOT00000034041
ankyrin repeat and death domain containing 1B
chr5_+_167141875 0.09 ENSRNOT00000089314
solute carrier family 2 member 5
chr14_-_2371883 0.09 ENSRNOT00000000077
phosphodiesterase 6B
chr18_+_27424328 0.09 ENSRNOT00000033784
kinesin family member 20A
chr3_-_431933 0.09 ENSRNOT00000033653
speckle type BTB/POZ protein like
chr3_-_56030744 0.09 ENSRNOT00000089637
coiled-coil domain containing 173
chr10_-_64657089 0.09 ENSRNOT00000080703
active BCR-related
chr15_+_87722221 0.09 ENSRNOT00000082688
sciellin
chr17_-_69711689 0.09 ENSRNOT00000041925
aldo-keto reductase family 1, member C12
chr10_-_97582188 0.09 ENSRNOT00000005076
regulator of G-protein signaling 9
chr8_-_61079526 0.09 ENSRNOT00000068658
pseudopodium-enriched atypical kinase 1
chr3_+_176818437 0.09 ENSRNOT00000087279
regulator of telomere elongation helicase 1
chr15_+_39638510 0.09 ENSRNOT00000037800
RCC1 and BTB domain containing protein 1
chr10_-_62184874 0.09 ENSRNOT00000004229
replication protein A1
chr20_-_31597830 0.09 ENSRNOT00000085877
collagen type XIII alpha 1 chain
chr8_+_29714285 0.09 ENSRNOT00000042890
opioid binding protein/cell adhesion molecule-like
chr1_-_219745654 0.09 ENSRNOT00000054848
hypothetical protein LOC689065
chr1_-_144601327 0.09 ENSRNOT00000029244
ENSRNOT00000078144
stabilizer of axonemal microtubules 2
chr1_-_277902279 0.09 ENSRNOT00000078416
actin-binding LIM protein 1
chr14_+_69800156 0.09 ENSRNOT00000072746
ligand dependent nuclear receptor corepressor-like
chr1_+_84685931 0.09 ENSRNOT00000063839
zinc finger protein 780B
chr1_-_265573117 0.09 ENSRNOT00000044195
ENSRNOT00000055915
Kv channel-interacting protein 2-like
chr10_-_110101872 0.09 ENSRNOT00000071893
coiled-coil domain containing 57
chr4_-_100303047 0.08 ENSRNOT00000018170
ENSRNOT00000084782
methionine adenosyltransferase 2A
chr13_-_80775230 0.08 ENSRNOT00000091389
ENSRNOT00000004762
flavin containing monooxygenase 2
chr10_+_66732390 0.08 ENSRNOT00000089538
neurofibromin 1
chrX_+_22285184 0.08 ENSRNOT00000086262
IQ motif and Sec7 domain 2
chr12_+_19231092 0.08 ENSRNOT00000045379
zinc finger with KRAB and SCAN domains 1
chr8_+_85503224 0.08 ENSRNOT00000012348
glutathione S-transferase alpha 4
chr1_+_280103695 0.08 ENSRNOT00000065289
enolase family member 4
chr10_-_27179254 0.08 ENSRNOT00000004619
gamma-aminobutyric acid type A receptor gamma 2 subunit
chr14_+_38192870 0.08 ENSRNOT00000077080
nuclear transcription factor, X-box binding-like 1
chr5_+_48006823 0.08 ENSRNOT00000076388
midasin AAA ATPase 1
chr4_+_152449270 0.08 ENSRNOT00000076733
RAD52 homolog, DNA repair protein
chrM_+_3904 0.08 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr5_+_173148884 0.08 ENSRNOT00000041753
hCG1994130-like
chr16_+_18648866 0.08 ENSRNOT00000014862
DPY30 domain containing 1
chr16_-_10802512 0.08 ENSRNOT00000079554
bone morphogenetic protein receptor type 1A
chr1_+_198960542 0.08 ENSRNOT00000072389
Snf2-related CREBBP activator protein
chr8_-_93390305 0.08 ENSRNOT00000056930
inhibitor of Bruton tyrosine kinase
chr1_-_59732409 0.08 ENSRNOT00000014824
hyaluronan synthase 1
chr2_+_238257031 0.08 ENSRNOT00000016066
integrator complex subunit 12
chr2_-_27296777 0.08 ENSRNOT00000080748
ankyrin repeat and death domain containing 1B
chr1_-_62316450 0.08 ENSRNOT00000079171

chr7_+_44146237 0.08 ENSRNOT00000058842
Ras association domain family member 9
chr4_-_161743847 0.08 ENSRNOT00000064174
ENSRNOT00000084173
ENSRNOT00000064215
integrin alpha FG-GAP repeat containing 2
chr1_+_252409268 0.08 ENSRNOT00000026219
lipase, family member M
chr9_+_73528681 0.08 ENSRNOT00000084340
unc-80 homolog, NALCN activator
chr11_+_88699222 0.08 ENSRNOT00000084177
FYVE, RhoGEF and PH domain containing 4
chr2_+_165805144 0.08 ENSRNOT00000073716
RAB interacting factor
chr14_+_83510278 0.08 ENSRNOT00000081161
POZ (BTB) and AT hook containing zinc finger 1
chr1_+_161401527 0.08 ENSRNOT00000015181
teneurin transmembrane protein 4
chr10_-_91661558 0.08 ENSRNOT00000043156

chr13_-_74520634 0.08 ENSRNOT00000077169
Ral GEF with PH domain and SH3 binding motif 2
chr2_-_57600820 0.08 ENSRNOT00000083247
NIPBL, cohesin loading factor
chr8_+_115546712 0.08 ENSRNOT00000079801
DDB1 and CUL4 associated factor 1
chr10_-_52290657 0.08 ENSRNOT00000005293
mitogen activated protein kinase kinase 4
chr8_+_21611319 0.08 ENSRNOT00000068461
zinc finger protein 846

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032197 transposition, RNA-mediated(GO:0032197)
0.1 0.1 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.1 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.2 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.1 GO:0018076 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.0 GO:1901219 regulation of cardiac chamber morphogenesis(GO:1901219) negative regulation of cardiac chamber morphogenesis(GO:1901220)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0 0.1 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) regulation of cellular response to drug(GO:2001038)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:1904412 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) mesendoderm development(GO:0048382) regulation of cardiac ventricle development(GO:1904412)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0035700 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.1 GO:0016203 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.0 0.1 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.1 GO:1905076 regulation of interleukin-17 secretion(GO:1905076) negative regulation of interleukin-17 secretion(GO:1905077)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:0036394 amylase secretion(GO:0036394)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:2000407 regulation of T cell extravasation(GO:2000407)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.0 GO:0032484 Ral protein signal transduction(GO:0032484)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.0 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.0 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:0051692 cellular oligosaccharide catabolic process(GO:0051692)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0071352 cellular response to interleukin-2(GO:0071352)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.0 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.0 0.1 GO:1902222 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.0 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.0 GO:2000078 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.0 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) uptake transmembrane transporter activity(GO:0015563)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
0.0 0.1 GO:0031762 follicle-stimulating hormone receptor binding(GO:0031762)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.0 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.0 GO:0031559 lanosterol synthase activity(GO:0000250) oxidosqualene cyclase activity(GO:0031559)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.0 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.0 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.0 GO:0001156 transcription factor activity, core RNA polymerase III binding(GO:0000995) TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)