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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Myf6

Z-value: 1.27

Motif logo

Transcription factors associated with Myf6

Gene Symbol Gene ID Gene Info
ENSRNOG00000004878 myogenic factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Myf6rn6_v1_chr7_-_49741540_497415400.138.3e-01Click!

Activity profile of Myf6 motif

Sorted Z-values of Myf6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_9037942 1.27 ENSRNOT00000036770
immediate early response 5-like
chr4_+_32373641 1.10 ENSRNOT00000076086
distal-less homeobox 6
chr15_-_61947764 0.92 ENSRNOT00000017400
chondromodulin
chr7_-_143967484 0.92 ENSRNOT00000081758
Sp7 transcription factor
chr6_-_110904288 0.71 ENSRNOT00000014645
interferon regulatory factor 2 binding protein-like
chr10_-_90151042 0.63 ENSRNOT00000055187
histone deacetylase 5
chr2_-_260596777 0.61 ENSRNOT00000009370
LIM homeobox 8
chr20_+_8165307 0.55 ENSRNOT00000000637
Pim-1 proto-oncogene, serine/threonine kinase
chr15_+_50891127 0.55 ENSRNOT00000020728
stanniocalcin 1
chr15_-_34198921 0.47 ENSRNOT00000024991
neural retina leucine zipper
chr3_-_58181971 0.43 ENSRNOT00000002076
distal-less homeobox 2
chr3_+_13838304 0.41 ENSRNOT00000025067
heat shock protein family A member 5
chr11_+_33909439 0.38 ENSRNOT00000002310
carbonyl reductase 3
chr18_-_29015552 0.38 ENSRNOT00000028713
neuregulin 2
chr12_+_19714324 0.37 ENSRNOT00000072303
similar to cell surface receptor FDFACT
chr1_-_82610350 0.34 ENSRNOT00000028177
cytochrome P450, family 2, subfamily s, polypeptide 1
chr2_+_210381829 0.34 ENSRNOT00000024611
ALX homeobox 3
chr11_+_33845463 0.34 ENSRNOT00000041838
carbonyl reductase 1
chr5_+_128865389 0.33 ENSRNOT00000068697
calreticulin 4
chr12_-_40227297 0.33 ENSRNOT00000030600
family with sequence similarity 109, member A
chr17_+_4846789 0.32 ENSRNOT00000073271
growth arrest-specific 1
chr19_-_25288335 0.32 ENSRNOT00000050214
nanos C2HC-type zinc finger 3
chr11_+_33812989 0.31 ENSRNOT00000042283
ENSRNOT00000075985
carbonyl reductase 1
chr17_-_89163113 0.31 ENSRNOT00000050445
ribosomal protein S19-like
chr2_-_192697800 0.30 ENSRNOT00000066614
small proline rich protein 4
chr12_+_22153983 0.29 ENSRNOT00000080775
ENSRNOT00000001894
procollagen C-endopeptidase enhancer
chr1_-_261446570 0.28 ENSRNOT00000020182
secreted frizzled-related protein 5
chr18_+_32594958 0.26 ENSRNOT00000018511
sprouty RTK signaling antagonist 4
chr5_+_98469047 0.26 ENSRNOT00000041374
leucine rich adaptor protein 1-like
chr10_+_90550147 0.26 ENSRNOT00000032944
frizzled class receptor 2
chr12_+_22165486 0.25 ENSRNOT00000001890
motile sperm domain containing 3
chr6_-_27190126 0.25 ENSRNOT00000068412
ENSRNOT00000013107
potassium two pore domain channel subfamily K member 3
chr1_+_7305658 0.25 ENSRNOT00000056227

chr2_+_187344056 0.24 ENSRNOT00000025314
nestin
chr4_-_132171153 0.24 ENSRNOT00000015058
ENSRNOT00000015075
prokineticin 2
chr10_+_55940533 0.24 ENSRNOT00000012061
similar to RIKEN cDNA A030009H04
chr7_+_129812789 0.24 ENSRNOT00000006357
cysteine-rich with EGF-like domains 2
chr10_+_105393072 0.23 ENSRNOT00000013359
UBA-like domain containing 2
chr5_-_17061837 0.23 ENSRNOT00000011892
proenkephalin
chr1_+_101783621 0.23 ENSRNOT00000067679
lemur tyrosine kinase 3
chr1_+_8933831 0.23 ENSRNOT00000076049
ENSRNOT00000016215
neuromedin B receptor
chr17_+_85500113 0.22 ENSRNOT00000091937

chr9_+_49479023 0.22 ENSRNOT00000050922
ENSRNOT00000077111
POU class 3 homeobox 3
chr16_+_83522162 0.22 ENSRNOT00000057386
collagen type IV alpha 1 chain
chr4_-_119889949 0.22 ENSRNOT00000033687
H1 histone family, member X
chr4_-_64330996 0.22 ENSRNOT00000016088
pleiotrophin
chr9_+_82120059 0.22 ENSRNOT00000057368
cyclin-dependent kinase 5 regulatory subunit 2
chr10_-_106976040 0.21 ENSRNOT00000003940
suppressor of cytokine signaling 3
chr20_-_3739968 0.21 ENSRNOT00000074049
ENSRNOT00000084918
coiled-coil alpha-helical rod protein 1
chr13_+_85818427 0.21 ENSRNOT00000077227
ENSRNOT00000006117
retinoid X receptor gamma
chr6_+_137997335 0.21 ENSRNOT00000006872
transmembrane protein 121
chr9_-_82699551 0.21 ENSRNOT00000020673
obscurin-like 1
chr11_+_31428358 0.20 ENSRNOT00000002827
oligodendrocyte transcription factor 1
chr6_-_45669148 0.20 ENSRNOT00000010092
radical S-adenosyl methionine domain containing 2
chr1_-_226501920 0.20 ENSRNOT00000050716
leucine rich repeat containing 10B
chr6_-_131926272 0.20 ENSRNOT00000084057
ENSRNOT00000088421
B-cell CLL/lymphoma 11B
chr4_-_77489535 0.20 ENSRNOT00000008728
protein disulfide isomerase family A, member 4
chr5_+_145079803 0.20 ENSRNOT00000084202
splicing factor proline and glutamine rich
chr16_-_20860767 0.20 ENSRNOT00000027275
ENSRNOT00000092417
growth differentiation factor 1
ceramide synthase 1
chr3_+_151285249 0.19 ENSRNOT00000055254
protein C receptor
chr1_+_101178104 0.19 ENSRNOT00000028072
parathyroid hormone 2
chr1_-_88111293 0.19 ENSRNOT00000077195
sprouty-related, EVH1 domain containing 3
chr2_-_188672226 0.19 ENSRNOT00000027970
ENSRNOT00000050868
ADAM metallopeptidase domain 15
chr9_+_81644975 0.18 ENSRNOT00000057480
ciliogenesis associated TTC17 interacting protein
chrX_-_14890606 0.18 ENSRNOT00000049864
similar to RIKEN cDNA B630019K06
chr17_+_76079720 0.18 ENSRNOT00000073933
proline and serine rich 2
chr9_+_94279155 0.18 ENSRNOT00000065805
protease, serine, 56
chr20_+_5351605 0.18 ENSRNOT00000089306
ENSRNOT00000041590
ENSRNOT00000081240
ENSRNOT00000082538
RT1 class Ia, locus A1
chr4_-_117490721 0.17 ENSRNOT00000021103
N-acetyltransferase 8 (GCN5-related) family member 3
chr6_+_132246602 0.17 ENSRNOT00000009896
cytochrome P450, family 46, subfamily a, polypeptide 1
chr9_-_15214596 0.17 ENSRNOT00000039102
transcription factor EB
chr17_+_49322205 0.17 ENSRNOT00000017713
POU domain, class 6, transcription factor 2
chr12_+_25119355 0.17 ENSRNOT00000034629
linker for activation of T cells family, member 2
chr18_+_27657628 0.17 ENSRNOT00000026303
early growth response 1
chr17_-_9791781 0.16 ENSRNOT00000090536
regulator of G-protein signaling 14
chr6_+_1657331 0.16 ENSRNOT00000049672
ENSRNOT00000079864
glutaminyl-peptide cyclotransferase
chr7_-_58587787 0.16 ENSRNOT00000005814
leucine rich repeat containing G protein coupled receptor 5
chr1_-_31122093 0.16 ENSRNOT00000016712
SOGA family member 3
chr14_-_80973456 0.16 ENSRNOT00000013257
HGF activator
chr6_+_98284170 0.16 ENSRNOT00000031979
ras homolog family member J
chr1_-_220883062 0.16 ENSRNOT00000084065
melanoma-associated antigen G1-like
chr4_+_157374318 0.16 ENSRNOT00000071027

chr8_-_108261021 0.16 ENSRNOT00000040710
40S ribosomal protein S25-like
chr3_-_147865393 0.16 ENSRNOT00000009852
SRY box 12
chr13_-_55878094 0.16 ENSRNOT00000014218
LIM homeobox 9
chr15_-_14622587 0.16 ENSRNOT00000086502
synaptoporin
chr1_-_47307488 0.16 ENSRNOT00000090033
ezrin
chr6_+_108820774 0.16 ENSRNOT00000089683
ENSRNOT00000080038
ENSRNOT00000006492
YLP motif containing 1
chr4_-_64831473 0.16 ENSRNOT00000033268
diacylglycerol kinase, iota
chr11_-_87449940 0.16 ENSRNOT00000002560
solute carrier family 7, member 4
chr8_+_115511974 0.16 ENSRNOT00000067683
translocase of inner mitochondrial membrane 8 homolog A1 (yeast)
chr5_-_153625869 0.16 ENSRNOT00000024464
chloride intracellular channel 4
chr8_+_49676540 0.15 ENSRNOT00000022032
ENSRNOT00000082205
FXYD domain-containing ion transport regulator 6
chr12_-_22126350 0.15 ENSRNOT00000076328
Sin3A-associated protein 25
chr9_+_9721105 0.15 ENSRNOT00000073042
ENSRNOT00000075494
complement C3
chr10_-_56429748 0.15 ENSRNOT00000020675
ENSRNOT00000092704
spermatid maturation 1
chr1_+_85213652 0.15 ENSRNOT00000092044
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr11_+_78029038 0.15 ENSRNOT00000089540
prolyl 3-hydroxylase 2
chr20_+_42966140 0.14 ENSRNOT00000000707
myristoylated alanine rich protein kinase C substrate
chr1_-_88690534 0.14 ENSRNOT00000072570
ovo-like zinc finger 3
chrX_-_124516705 0.14 ENSRNOT00000061493
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
chr13_-_37287458 0.14 ENSRNOT00000003391
insulin induced gene 2
chr10_-_108196217 0.14 ENSRNOT00000075440
chromobox 4
chr19_+_57484634 0.14 ENSRNOT00000025695
ARV1 homolog, fatty acid homeostasis modulator
chr4_-_181477281 0.14 ENSRNOT00000055463
MANSC domain containing 4
chr13_+_85110098 0.14 ENSRNOT00000087368
family with sequence similarity 78, member B
chr5_-_36683356 0.14 ENSRNOT00000009043
POU class 3 homeobox 2
chr1_+_101214593 0.14 ENSRNOT00000028086
TEA domain transcription factor 2
chr17_+_9639330 0.14 ENSRNOT00000018232
docking protein 3
chr2_-_188645196 0.14 ENSRNOT00000083793
ephrin A3
chr19_+_25391700 0.14 ENSRNOT00000011163
ribonucleotide reductase M2 polypeptide
chr3_+_160231914 0.14 ENSRNOT00000014411
potassium two pore domain channel subfamily K member 15
chr8_+_107106982 0.13 ENSRNOT00000072574
hypothetical protein LOC684395
chr4_+_96562725 0.13 ENSRNOT00000009094
neuron-derived neurotrophic factor
chr1_+_101412736 0.13 ENSRNOT00000067468
luteinizing hormone beta polypeptide
chr19_+_26142720 0.13 ENSRNOT00000005270
similar to RIKEN cDNA 2310036O22
chr6_+_26602144 0.13 ENSRNOT00000008037
urocortin
chr12_-_42492526 0.13 ENSRNOT00000084018
T-box 3
chr20_-_4677506 0.13 ENSRNOT00000061297
RT1 class I, locus CE6
chr2_+_23385183 0.13 ENSRNOT00000014860
arylsulfatase B
chr10_+_45289741 0.13 ENSRNOT00000066190
histone cluster 3, H2ba
chrX_+_62366453 0.13 ENSRNOT00000089828
aristaless related homeobox
chr16_-_48437223 0.13 ENSRNOT00000013005
ENSRNOT00000059401
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr4_-_178168690 0.13 ENSRNOT00000020729
SRY box 5
chr20_-_5533448 0.13 ENSRNOT00000000568
cutA divalent cation tolerance homolog
chr20_-_4792450 0.13 ENSRNOT00000091344
RT1 class I, locus CE6
chr20_-_5533600 0.13 ENSRNOT00000072319
cutA divalent cation tolerance homolog
chr10_-_14022452 0.13 ENSRNOT00000016554
neuropeptide W
chr8_+_130401470 0.13 ENSRNOT00000043346
zinc finger and BTB domain containing 47
chr5_-_155258392 0.13 ENSRNOT00000017065
complement C1q C chain
chrX_+_88298266 0.12 ENSRNOT00000041508

chrX_-_38196060 0.12 ENSRNOT00000006741
ENSRNOT00000006438
SH3 domain-containing kinase-binding protein 1
chrX_-_106607352 0.12 ENSRNOT00000082858

chr13_-_112099336 0.12 ENSRNOT00000009158
ENSRNOT00000044161
calcium/calmodulin-dependent protein kinase IG
chr19_-_53754602 0.12 ENSRNOT00000035651
family with sequence similarity 92, member B
chr20_-_4792283 0.12 ENSRNOT00000061027
RT1 class I, locus1
chr4_+_55715744 0.12 ENSRNOT00000010429
ADP-ribosylation factor 5
chr1_-_218920094 0.12 ENSRNOT00000022213
LDL receptor related protein 5
chr2_+_188844073 0.12 ENSRNOT00000028117
potassium calcium-activated channel subfamily N member 3
chr7_+_93376277 0.12 ENSRNOT00000017602
ribosomal protein S25-like
chr8_+_48472824 0.12 ENSRNOT00000010463
ENSRNOT00000090780
melanoma cell adhesion molecule
chr9_-_78969013 0.12 ENSRNOT00000019772
ENSRNOT00000057585
fibronectin 1
chr1_-_218100272 0.11 ENSRNOT00000028411
ENSRNOT00000088588
cyclin D1
chr1_-_220096319 0.11 ENSRNOT00000091787
ENSRNOT00000073983
copper chaperone for superoxide dismutase
chr18_+_56071478 0.11 ENSRNOT00000025344
ENSRNOT00000025354
CD74 molecule
chr7_+_123168811 0.11 ENSRNOT00000007091
cold shock domain containing C2
chr10_+_93520132 0.11 ENSRNOT00000055137
mannose receptor, C type 2
chr8_-_22874637 0.11 ENSRNOT00000064551
ENSRNOT00000090424
dedicator of cytokinesis 6
chr2_-_250235435 0.11 ENSRNOT00000088618
LIM domain only 4
chr1_+_220416018 0.11 ENSRNOT00000027233
beta-1,4-glucuronyltransferase 1
chr10_+_31561895 0.11 ENSRNOT00000048485
hepatitis A virus cellular receptor 2
chr5_-_155381732 0.11 ENSRNOT00000033670
zinc finger and BTB domain containing 40
chr14_-_84170301 0.11 ENSRNOT00000080413
solute carrier family 35, member E4
chr12_+_47218969 0.11 ENSRNOT00000081343
ENSRNOT00000038395
unc-119 lipid binding chaperone B
chr2_-_250241590 0.10 ENSRNOT00000077221
ENSRNOT00000067502
LIM domain only 4
chr14_-_34218961 0.10 ENSRNOT00000072588
similar to Exocyst complex component 1 (Exocyst complex component Sec3)
chr7_+_145117951 0.10 ENSRNOT00000055272
phosphodiesterase 1B
chr9_+_81644355 0.10 ENSRNOT00000071700
ciliogenesis associated TTC17 interacting protein
chr9_-_79898912 0.10 ENSRNOT00000022076
membrane associated ring-CH-type finger 4
chr19_+_10731855 0.10 ENSRNOT00000022277
plasmolipin
chr2_+_192538899 0.10 ENSRNOT00000045691
ENSRNOT00000085931
small proline-rich protein 2I-like
chr1_-_78851719 0.10 ENSRNOT00000022603
calmodulin 2
chr2_+_198772937 0.10 ENSRNOT00000028812
integrin subunit alpha 10
chr20_-_28814636 0.10 ENSRNOT00000086030
septin 10
chr1_+_21525421 0.10 ENSRNOT00000017911
arginase 1
chr7_-_134560713 0.10 ENSRNOT00000006621
YY1 associated factor 2
chr7_+_14559878 0.10 ENSRNOT00000007428
cytochrome P450, family 4, subfamily f, polypeptide 5
chr15_+_52451161 0.10 ENSRNOT00000018725
docking protein 2
chr9_+_98313632 0.10 ENSRNOT00000027012
receptor activity modifying protein 1
chr6_+_10912383 0.10 ENSRNOT00000061747
ENSRNOT00000086247
tetratricopeptide repeat domain 7A
chr1_+_261389804 0.10 ENSRNOT00000064160
MARVEL domain containing 1
chr1_+_79981355 0.10 ENSRNOT00000020134
dystrophia myotonica, WD repeat containing
chr15_-_33725188 0.09 ENSRNOT00000083941
zinc finger homeobox 2
chr9_-_82461903 0.09 ENSRNOT00000026654
protein tyrosine phosphatase, receptor type, N
chr18_+_83777665 0.09 ENSRNOT00000018682
cerebellin 2 precursor
chr4_-_83137527 0.09 ENSRNOT00000039580
JAZF zinc finger 1
chr2_-_183031214 0.09 ENSRNOT00000013260
similar to RIKEN cDNA D930015E06
chr8_+_118333706 0.09 ENSRNOT00000028278
chondroitin sulfate proteoglycan 5
chr17_+_13670520 0.09 ENSRNOT00000019442
SHC adaptor protein 3
chr1_-_210739600 0.09 ENSRNOT00000031734
transcription elongation regulator 1-like
chr13_+_63526486 0.09 ENSRNOT00000003788
BMP/retinoic acid inducible neural specific 3
chr2_-_219262901 0.09 ENSRNOT00000037068
G-protein coupled receptor 88
chr8_+_117780891 0.09 ENSRNOT00000077236
shisa family member 5
chr1_+_226897625 0.09 ENSRNOT00000029443
solute carrier family 15 member 3
chr17_-_54714914 0.09 ENSRNOT00000024336
zinc finger E-box binding homeobox 1
chr9_+_80118029 0.09 ENSRNOT00000023068
insulin-like growth factor binding protein 2
chr1_-_101131012 0.09 ENSRNOT00000082283
ENSRNOT00000093498
ENSRNOT00000093559
fms-related tyrosine kinase 3 ligand
ribosomal protein L13A
chr19_-_43596801 0.09 ENSRNOT00000025625
fatty acid 2-hydroxylase
chr8_+_119135013 0.09 ENSRNOT00000056114
protease, serine, 50
chr1_-_222177421 0.09 ENSRNOT00000078393
estrogen related receptor, alpha
chr13_-_97282299 0.09 ENSRNOT00000004244
Mix paired-like homeobox 1
chr4_-_170620703 0.09 ENSRNOT00000011930
phospholipase B domain containing 1
chr2_-_250232295 0.08 ENSRNOT00000082132
LIM domain only 4
chr1_-_265420503 0.08 ENSRNOT00000072223
F-box and WD repeat domain containing 4
chr2_-_94730308 0.08 ENSRNOT00000081553
zinc finger and BTB domain containing 10
chr11_-_83546674 0.08 ENSRNOT00000044896
Eph receptor B3
chr6_-_65319527 0.08 ENSRNOT00000005618
syntaxin binding protein 6
chr3_+_175144495 0.08 ENSRNOT00000082601
ENSRNOT00000088026
cadherin 4
chr7_-_119996824 0.08 ENSRNOT00000011079
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_-_140401686 0.08 ENSRNOT00000083955
FK506 binding protein 11

Network of associatons between targets according to the STRING database.

First level regulatory network of Myf6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.2 0.5 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 1.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 0.4 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.3 GO:2000040 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.3 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.1 0.3 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.3 GO:0021586 pons maturation(GO:0021586)
0.1 0.2 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
0.1 0.2 GO:0031989 bombesin receptor signaling pathway(GO:0031989)
0.1 0.6 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.2 GO:0072720 response to dithiothreitol(GO:0072720)
0.1 0.2 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.1 0.2 GO:0045105 intermediate filament polymerization or depolymerization(GO:0045105)
0.1 0.2 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
0.1 0.2 GO:0072021 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
0.1 0.2 GO:0010070 zygote asymmetric cell division(GO:0010070)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.6 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.1 0.2 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.1 0.2 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
0.0 0.1 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.3 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.0 0.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.1 GO:0014736 negative regulation of muscle atrophy(GO:0014736)
0.0 0.3 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.1 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.0 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.1 GO:1902023 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0036166 DNA methylation on cytosine within a CG sequence(GO:0010424) phenotypic switching(GO:0036166)
0.0 0.0 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.0 0.1 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.3 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.0 GO:0060066 oviduct development(GO:0060066)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0 0.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.0 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.3 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.1 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.0 0.0 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.0 GO:2000568 defense response to nematode(GO:0002215) memory T cell activation(GO:0035709) positive regulation of memory T cell differentiation(GO:0043382) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.7 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.0 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.0 GO:0060021 palate development(GO:0060021)
0.0 0.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:0072710 response to hydroxyurea(GO:0072710) cellular response to hydroxyurea(GO:0072711)
0.0 0.0 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.0 GO:0006567 threonine catabolic process(GO:0006567)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.0 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) high-density lipoprotein particle assembly(GO:0034380)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0044393 TCR signalosome(GO:0036398) microspike(GO:0044393)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.2 0.6 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.2 GO:0004946 bombesin receptor activity(GO:0004946)
0.1 0.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.2 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0099567 N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0071723 lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.0 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling