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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nfatc2

Z-value: 0.68

Motif logo

Transcription factors associated with Nfatc2

Gene Symbol Gene ID Gene Info
ENSRNOG00000012175 nuclear factor of activated T-cells 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc2rn6_v1_chr3_-_165360292_165360292-0.177.9e-01Click!

Activity profile of Nfatc2 motif

Sorted Z-values of Nfatc2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_107760550 0.52 ENSRNOT00000077091
ENSRNOT00000051638
Meis homeobox 2
chr7_-_130368819 0.34 ENSRNOT00000064328
synaptonemal complex central element protein 3
chr1_-_15301998 0.32 ENSRNOT00000016400
solute carrier family 35, member D3
chr15_+_10120206 0.31 ENSRNOT00000033048
retinoic acid receptor, beta
chr19_-_6031655 0.30 ENSRNOT00000092016

chr15_+_50891127 0.29 ENSRNOT00000020728
stanniocalcin 1
chr14_+_43694183 0.28 ENSRNOT00000046342
similar to ribosomal protein S23
chr2_-_123851854 0.26 ENSRNOT00000023327
interleukin 2
chr2_-_30127269 0.26 ENSRNOT00000023869
CART prepropeptide
chr17_-_89163113 0.24 ENSRNOT00000050445
ribosomal protein S19-like
chr11_+_33812989 0.24 ENSRNOT00000042283
ENSRNOT00000075985
carbonyl reductase 1
chrX_-_138148967 0.23 ENSRNOT00000033968
FERM domain containing 7
chr9_+_25304876 0.23 ENSRNOT00000065053
transcription factor AP-2 delta
chr2_-_251532312 0.23 ENSRNOT00000019501
cysteine-rich, angiogenic inducer, 61
chr1_-_47502952 0.22 ENSRNOT00000025580
T-cell activation RhoGTPase activating protein
chr12_+_19714324 0.22 ENSRNOT00000072303
similar to cell surface receptor FDFACT
chr17_-_51912496 0.20 ENSRNOT00000019272
inhibin beta A subunit
chr6_-_77421286 0.20 ENSRNOT00000011453
NK2 homeobox 1
chr11_+_33863500 0.19 ENSRNOT00000072384
carbonyl reductase [NADPH] 1-like
chr10_-_70871066 0.19 ENSRNOT00000015139
C-C motif chemokine ligand 3
chr2_-_19808937 0.19 ENSRNOT00000044237
ATPase H+ transporting accessory protein 1 like
chr3_+_59153280 0.18 ENSRNOT00000002066
cell division cycle associated 7
chr8_-_33661049 0.16 ENSRNOT00000068037
Fli-1 proto-oncogene, ETS transcription factor
chr4_-_50312608 0.16 ENSRNOT00000010019
Fez family zinc finger 1
chr9_-_15274917 0.15 ENSRNOT00000019650
progastricsin
chr10_+_49259194 0.15 ENSRNOT00000091100
ENSRNOT00000004390
F-box and WD repeat domain containing 10
chrX_-_115175299 0.15 ENSRNOT00000074322
doublecortin
chr8_+_106449321 0.15 ENSRNOT00000018622
retinol binding protein 1
chr5_-_153924896 0.14 ENSRNOT00000065247
grainyhead-like transcription factor 3
chr11_-_32550539 0.14 ENSRNOT00000002715
regulator of calcineurin 1
chrX_+_32495809 0.14 ENSRNOT00000020999
similar to RIKEN cDNA 1700045I19
chr1_+_279798187 0.14 ENSRNOT00000024065
pancreatic lipase
chr3_+_151285249 0.13 ENSRNOT00000055254
protein C receptor
chr2_+_206064394 0.13 ENSRNOT00000077739
synaptotagmin 6
chr3_+_132560506 0.13 ENSRNOT00000005920
serine palmitoyltransferase, long chain base subunit 3
chr12_-_51965779 0.13 ENSRNOT00000056733
replication protein A3-like
chr16_-_47537476 0.13 ENSRNOT00000050279
claudin 24
chr5_+_122508388 0.13 ENSRNOT00000038410
Tctex1 domain containing 1
chr1_-_89369960 0.13 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr4_-_16130848 0.13 ENSRNOT00000042914
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr2_+_252263386 0.13 ENSRNOT00000092913
ENSRNOT00000084034
ENSRNOT00000041186
ENSRNOT00000092931
SSX family member 2 interacting protein
chr8_-_104155775 0.12 ENSRNOT00000042885
60S ribosomal protein L31-like
chr2_+_203768729 0.12 ENSRNOT00000018895
immunoglobulin superfamily, member 3
chr7_-_120919261 0.12 ENSRNOT00000019612
Josephin domain containing 1
chr11_+_33845463 0.11 ENSRNOT00000041838
carbonyl reductase 1
chr10_+_68588789 0.11 ENSRNOT00000049614

chr1_+_89220083 0.11 ENSRNOT00000093144
dermokine
chr5_-_51468425 0.11 ENSRNOT00000007449
leucine rich repeat and Ig domain containing 2
chr10_-_85947938 0.11 ENSRNOT00000037318
ENSRNOT00000082427
ADP-ribosylation factor like GTPase 5C
chr10_-_38969501 0.11 ENSRNOT00000090691
ENSRNOT00000081309
ENSRNOT00000010029
interleukin 4
chr5_+_146294030 0.11 ENSRNOT00000073637

chr3_+_64190973 0.11 ENSRNOT00000011342

chr9_-_73948583 0.11 ENSRNOT00000018097
myosin, light chain 1
chr8_+_52829085 0.11 ENSRNOT00000007754
similar to hypothetical protein FLJ20010
chr10_+_103874383 0.11 ENSRNOT00000038935
otopetrin 2
chr10_+_81984560 0.11 ENSRNOT00000072482

chr2_+_211337271 0.11 ENSRNOT00000045155
cytochrome c oxidase subunit 6B1
chr16_-_81583374 0.10 ENSRNOT00000092501
transmembrane and coiled-coil domain-containing protein 3
chr13_-_82005741 0.10 ENSRNOT00000076404
methyltransferase like 11B
chr7_-_107223047 0.10 ENSRNOT00000007250
ENSRNOT00000084875
leucine rich repeat containing 6
chr4_-_178441547 0.10 ENSRNOT00000087434
ENSRNOT00000055542
SRY box 5
chr4_-_126071261 0.10 ENSRNOT00000080234
dynein light chain 1-like
chr1_+_44311513 0.10 ENSRNOT00000065386
T-cell lymphoma invasion and metastasis 2
chr1_-_24302298 0.10 ENSRNOT00000083452
serum/glucocorticoid regulated kinase 1
chr17_+_60287203 0.10 ENSRNOT00000025585
armadillo repeat containing 4
chr4_-_29778039 0.10 ENSRNOT00000074177
sarcoglycan, epsilon
chr2_+_11658568 0.10 ENSRNOT00000076408
ENSRNOT00000076416
ENSRNOT00000076992
ENSRNOT00000075931
ENSRNOT00000076136
ENSRNOT00000076481
ENSRNOT00000076084
ENSRNOT00000076230
ENSRNOT00000076710
ENSRNOT00000076239
myocyte enhancer factor 2C
chr2_-_102370757 0.10 ENSRNOT00000074255
transcription elongation factor A (SII)-like 6
chr14_-_34218961 0.10 ENSRNOT00000072588
similar to Exocyst complex component 1 (Exocyst complex component Sec3)
chr20_+_42966140 0.10 ENSRNOT00000000707
myristoylated alanine rich protein kinase C substrate
chr2_-_77784522 0.09 ENSRNOT00000030328
similar to RIKEN cDNA 0610040D20
chr1_+_31436712 0.09 ENSRNOT00000038102

chr7_+_132857628 0.09 ENSRNOT00000005438
leucine-rich repeat kinase 2
chr6_+_83421882 0.09 ENSRNOT00000084258
leucine rich repeat and fibronectin type III domain containing 5
chr1_-_24190896 0.09 ENSRNOT00000016121
serum/glucocorticoid regulated kinase 1
chr10_+_48773828 0.09 ENSRNOT00000004113
phosphatidylinositol glycan anchor biosynthesis, class L
chr5_-_160405050 0.09 ENSRNOT00000081899
chymotrypsin C
chrX_+_76786466 0.09 ENSRNOT00000090665
fibroblast growth factor 16
chr3_+_4233111 0.09 ENSRNOT00000042910
lipocalin 1
chr9_+_67699379 0.09 ENSRNOT00000091237
ENSRNOT00000088183
cytotoxic T-lymphocyte-associated protein 4
chr17_-_81187739 0.09 ENSRNOT00000063911
3-hydroxyacyl-CoA dehydratase 1
chr18_+_29993361 0.09 ENSRNOT00000075810
protocadherin alpha 4
chr17_-_15519060 0.09 ENSRNOT00000093624
asporin-like 1
chr1_-_175676699 0.09 ENSRNOT00000030474
lymphatic vessel endothelial hyaluronan receptor 1
chr6_-_114488880 0.09 ENSRNOT00000087560

chr7_-_121232741 0.09 ENSRNOT00000023196
platelet derived growth factor subunit B
chr12_+_22665112 0.09 ENSRNOT00000001918
adaptor-related protein complex 1, sigma 1 subunit
chr1_+_72860218 0.09 ENSRNOT00000024547
synaptotagmin 5
chr20_-_32133431 0.09 ENSRNOT00000000443
serglycin
chr19_-_14945302 0.09 ENSRNOT00000079391

chr13_-_107886476 0.09 ENSRNOT00000077282
potassium two pore domain channel subfamily K member 2
chr3_+_170252901 0.08 ENSRNOT00000005871
melanocortin 3 receptor
chr14_+_70780623 0.08 ENSRNOT00000083871
ENSRNOT00000058803
LIM domain binding 2
chr17_+_56109549 0.08 ENSRNOT00000022190
mitogen-activated protein kinase kinase kinase 8
chr4_-_16130563 0.08 ENSRNOT00000090240
ENSRNOT00000034969
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr2_+_216863428 0.08 ENSRNOT00000068413
collagen type XI alpha 1 chain
chr8_-_87419564 0.08 ENSRNOT00000015365
filamin A interacting protein 1
chr15_-_61772516 0.08 ENSRNOT00000015605
ENSRNOT00000093399
WW domain binding protein 4
chr14_-_43694584 0.08 ENSRNOT00000041866

chr5_-_135994848 0.08 ENSRNOT00000067675
BTB domain containing 19
chr1_-_100993269 0.08 ENSRNOT00000027777
BCL2 like 12
chr1_+_166433109 0.08 ENSRNOT00000026428
StAR-related lipid transfer domain containing 10
chr1_-_80331626 0.08 ENSRNOT00000022577

chr5_-_147817852 0.08 ENSRNOT00000071940
doublecortin domain containing 2B
chr17_+_43734461 0.08 ENSRNOT00000072564
histone cluster 1, H1d
chrX_-_136150209 0.08 ENSRNOT00000048498
ecto-NOX disulfide-thiol exchanger 2
chr8_-_118378460 0.08 ENSRNOT00000047247
similar to ribosomal protein S23
chr18_-_28516209 0.08 ENSRNOT00000072580
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr11_-_60679555 0.08 ENSRNOT00000059735
coiled-coil domain containing 80
chr15_-_28803529 0.08 ENSRNOT00000017738

chr9_+_40817654 0.08 ENSRNOT00000037392

chr2_-_184993341 0.08 ENSRNOT00000071580
family with sequence similarity 160, member A1
chr12_-_12712742 0.08 ENSRNOT00000034483
radial spoke head 10 homolog B
chr16_-_69280109 0.07 ENSRNOT00000058595

chr1_-_53563032 0.07 ENSRNOT00000044831
tubulin tyrosine ligase like 2
chr1_-_88989552 0.07 ENSRNOT00000034001
Rho GTPase activating protein 33
chr2_+_22910236 0.07 ENSRNOT00000078266
homer scaffolding protein 1
chr6_+_135890931 0.07 ENSRNOT00000042973
TNF alpha induced protein 2
chr5_+_74649765 0.07 ENSRNOT00000075952
paralemmin 2
chr7_-_35550247 0.07 ENSRNOT00000049211
ribosomal protein L31-like 3
chr3_+_72191533 0.07 ENSRNOT00000044319
ubiquitin-conjugating enzyme E2L 6
chr2_+_193866951 0.07 ENSRNOT00000013393
S100 calcium binding protein A11
chr17_+_14469488 0.07 ENSRNOT00000060670

chr1_+_266255797 0.07 ENSRNOT00000027047
tripartite motif-containing 8
chr14_-_92495894 0.07 ENSRNOT00000064483
cordon-bleu WH2 repeat protein
chr11_-_61530567 0.07 ENSRNOT00000076277
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr3_-_111422203 0.07 ENSRNOT00000084290
Opa interacting protein 5
chr5_-_147761983 0.07 ENSRNOT00000012936
LCK proto-oncogene, Src family tyrosine kinase
chr1_+_30681681 0.07 ENSRNOT00000015395
R-spondin 3
chr13_-_82006005 0.07 ENSRNOT00000039581
methyltransferase like 11B
chr20_+_295250 0.07 ENSRNOT00000000955
chloride intracellular channel 2
chr3_+_65815080 0.07 ENSRNOT00000006429
ubiquitin-conjugating enzyme E2E 3
chr20_-_10013190 0.07 ENSRNOT00000084726
ENSRNOT00000089112
radial spoke head 1 homolog
chr4_+_169147243 0.07 ENSRNOT00000011580
epithelial membrane protein 1
chr9_+_17911944 0.07 ENSRNOT00000080940
spermatogenesis associated, serine-rich 1
chr1_-_48360131 0.07 ENSRNOT00000051927
ENSRNOT00000023116
solute carrier family 22 member 2
chr15_-_52317219 0.07 ENSRNOT00000016555
dematin actin binding protein
chr12_-_46414434 0.07 ENSRNOT00000041281
citron rho-interacting serine/threonine kinase
chr3_+_94035905 0.07 ENSRNOT00000014767
similar to RIKEN cDNA A930018P22
chr1_+_78767911 0.07 ENSRNOT00000022360
protein kinase D2
chr17_-_389967 0.07 ENSRNOT00000023865
fructose-bisphosphatase 2
chr20_+_44060731 0.07 ENSRNOT00000000737
laminin subunit alpha 4
chr5_+_16845631 0.07 ENSRNOT00000047889
coiled-coil-helix-coiled-coil-helix domain containing 7
chr10_-_78690857 0.07 ENSRNOT00000089255
similar to glyceraldehyde-3-phosphate dehydrogenase
chr6_+_56625650 0.07 ENSRNOT00000008803
mesenchyme homeobox 2
chr19_+_53055745 0.06 ENSRNOT00000074430
forkhead box L1
chr2_-_46476203 0.06 ENSRNOT00000015217
NADH:ubiquinone oxidoreductase subunit S4
chr1_+_129255396 0.06 ENSRNOT00000040147
family with sequence similarity 169, member B
chr3_+_112242270 0.06 ENSRNOT00000080533
ENSRNOT00000082876
calpain 3
chr18_-_62476700 0.06 ENSRNOT00000048429
cytochrome c, somatic
chr16_-_68700296 0.06 ENSRNOT00000060162

chr17_+_57031766 0.06 ENSRNOT00000092187
ENSRNOT00000068545
cAMP responsive element modulator
chr6_+_27975849 0.06 ENSRNOT00000060810
dystrobrevin, beta
chr7_+_35773928 0.06 ENSRNOT00000034639
centrosomal protein 83
chr4_-_80313411 0.06 ENSRNOT00000041621
similar to ribosomal protein L27a
chr20_-_22459025 0.06 ENSRNOT00000000792
early growth response 2
chr2_-_89498395 0.06 ENSRNOT00000068507

chr7_+_65005791 0.06 ENSRNOT00000005794
protein LLP homolog
chr9_+_77320726 0.06 ENSRNOT00000068450
sperm associated antigen 16
chr2_-_178612470 0.06 ENSRNOT00000013499
transmembrane protein 144
chr15_-_34352673 0.06 ENSRNOT00000064916
neural precursor cell expressed, developmentally down-regulated 8
chr10_+_3411380 0.06 ENSRNOT00000004346
similar to RIKEN cDNA 2900011O08
chr7_-_36499784 0.06 ENSRNOT00000011948
suppressor of cytokine signaling 2
chr1_+_228684136 0.06 ENSRNOT00000028608
olfactory receptor 337
chr6_+_95816749 0.06 ENSRNOT00000008880
SIX homeobox 6
chr10_-_50402616 0.06 ENSRNOT00000004546
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr3_-_151486693 0.06 ENSRNOT00000073736
ENSRNOT00000071099
growth differentiation factor 5
chr18_+_29960072 0.06 ENSRNOT00000071366

chr3_+_22829817 0.06 ENSRNOT00000082561
NIMA-related kinase 6
chr12_+_37668369 0.06 ENSRNOT00000001419
cyclin-dependent kinase 2 associated protein 1
chr2_+_195603599 0.06 ENSRNOT00000028263
C2 calcium-dependent domain containing 4D
chr4_-_154044493 0.06 ENSRNOT00000076318
IQ motif and Sec7 domain 3
chrX_-_105568343 0.06 ENSRNOT00000029807
armadillo repeat containing, X-linked 6
chr17_+_57074525 0.06 ENSRNOT00000020012
ENSRNOT00000074146
cAMP responsive element modulator
chr20_-_10013559 0.06 ENSRNOT00000091623
radial spoke head 1 homolog
chr6_+_86131242 0.06 ENSRNOT00000039337
FAU, ubiquitin like and ribosomal protein S30 fusion
chr5_+_135536413 0.06 ENSRNOT00000023132
peroxiredoxin 1
chr3_+_93351619 0.06 ENSRNOT00000011035
E74-like factor 5
chr9_-_27761733 0.06 ENSRNOT00000040034
potassium voltage-gated channel subfamily Q member 5
chr1_+_37507276 0.06 ENSRNOT00000047627
adenylate cyclase 2
chrX_+_110670119 0.06 ENSRNOT00000014811
ENSRNOT00000089579
hypothetical protein LOC680663
chr5_-_146069670 0.06 ENSRNOT00000072793
hypothetical protein LOC682102
chrX_-_72078551 0.06 ENSRNOT00000076978
ribosomal protein S4, X-linked
chr3_+_126335863 0.06 ENSRNOT00000028904
bone morphogenetic protein 2
chr18_+_29987206 0.06 ENSRNOT00000027383
protocadherin alpha 4
chrX_+_112311251 0.06 ENSRNOT00000086698

chr10_+_53740841 0.06 ENSRNOT00000004295
myosin heavy chain 2
chr6_-_91581262 0.06 ENSRNOT00000034507

chr1_+_53220397 0.06 ENSRNOT00000089989

chr20_+_32450733 0.05 ENSRNOT00000036449
radial spoke head 4 homolog A
chr20_+_33945829 0.05 ENSRNOT00000064063
radial spoke head protein 4 homolog A
chr5_-_2803855 0.05 ENSRNOT00000009490
ribosomal protein S8-like
chr4_-_170932618 0.05 ENSRNOT00000007779
Rho GDP dissociation inhibitor beta
chr6_+_55374984 0.05 ENSRNOT00000091682
anterior gradient 3, protein disulphide isomerase family member
chr10_-_49196177 0.05 ENSRNOT00000084418
zinc finger protein 286A
chr2_-_44907030 0.05 ENSRNOT00000013979
glutathione peroxidase 8
chr8_+_93439648 0.05 ENSRNOT00000043008
ribosomal protein S20-like
chr10_-_56412544 0.05 ENSRNOT00000020578
transmembrane protein 102
chr3_+_97723901 0.05 ENSRNOT00000080416
metallophosphoesterase domain containing 2
chr3_-_150062311 0.05 ENSRNOT00000022115
E2F transcription factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.3 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.3 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.0 0.2 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048) positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0072209 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760) cellular response to bile acid(GO:1903413)
0.0 0.0 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.1 GO:2000468 positive regulation of protein autoubiquitination(GO:1902499) regulation of peroxidase activity(GO:2000468)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.1 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.4 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.0 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.0 0.0 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.0 GO:0036023 embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.1 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.0 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608) regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.0 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.0 GO:0032919 spermine acetylation(GO:0032919)
0.0 0.0 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.0 0.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.0 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982) positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.0 GO:0033563 spinal cord ventral commissure morphogenesis(GO:0021965) dorsal/ventral axon guidance(GO:0033563)
0.0 0.0 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.1 GO:0032707 embryonic olfactory bulb interneuron precursor migration(GO:0021831) negative regulation of interleukin-23 production(GO:0032707)
0.0 0.0 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043511 inhibin complex(GO:0043511)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0070449 elongin complex(GO:0070449)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.0 GO:1990836 lysosomal matrix(GO:1990836)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.2 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.0 0.1 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0032564 dATP binding(GO:0032564)
0.0 0.0 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.0 GO:0019809 spermidine binding(GO:0019809)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels