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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Tbx4

Z-value: 0.23

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Transcription factors associated with Tbx4

Gene Symbol Gene ID Gene Info
ENSRNOG00000003544 T-box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx4rn6_v1_chr10_+_73333119_733331190.069.2e-01Click!

Activity profile of Tbx4 motif

Sorted Z-values of Tbx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_131351587 0.11 ENSRNOT00000010835
BTB domain containing 3
chr5_-_12563429 0.09 ENSRNOT00000059625
suppression of tumorigenicity 18
chr1_-_264975132 0.09 ENSRNOT00000021748
ladybird homeobox 1
chr1_+_238222521 0.06 ENSRNOT00000024000
aldehyde dehydrogenase 1 family, member A1
chr15_+_19690194 0.06 ENSRNOT00000010612
serine/threonine/tyrosine interacting protein
chr3_+_151508361 0.05 ENSRNOT00000055251
centrosomal protein 250
chr5_+_143500441 0.05 ENSRNOT00000045513
glutamate ionotropic receptor kainate type subunit 3
chr15_+_8739589 0.05 ENSRNOT00000071751
nuclear receptor subfamily 1, group D, member 2
chr1_+_187149453 0.05 ENSRNOT00000082738
xylosyltransferase 1
chr16_+_46731403 0.05 ENSRNOT00000017624
teneurin transmembrane protein 3
chr12_+_52359310 0.05 ENSRNOT00000071857
ENSRNOT00000065893
fibrosin-like 1
chr18_+_53609214 0.05 ENSRNOT00000077443
solute carrier family 27 member 6
chr16_+_32457521 0.04 ENSRNOT00000083579
chloride voltage-gated channel 3
chr5_+_136683592 0.04 ENSRNOT00000085527
solute carrier family 6 member 9
chr9_-_63637677 0.04 ENSRNOT00000049259
SATB homeobox 2
chr6_+_28323647 0.04 ENSRNOT00000089093
DNA methyltransferase 3 alpha
chr1_+_198960542 0.04 ENSRNOT00000072389
Snf2-related CREBBP activator protein
chr11_-_4397361 0.04 ENSRNOT00000046370
cell adhesion molecule 2
chr2_-_177924970 0.03 ENSRNOT00000029340
Rap guanine nucleotide exchange factor 2
chr19_-_37907714 0.03 ENSRNOT00000026361
chymotrypsin-like
chr2_-_62634785 0.03 ENSRNOT00000017937
PDZ domain containing 2
chr10_-_94488180 0.03 ENSRNOT00000015818
growth hormone 1
chr2_+_74360622 0.03 ENSRNOT00000014013
cadherin 18
chr2_-_206274079 0.03 ENSRNOT00000056079
homeodomain interacting protein kinase 1
chr1_-_261446570 0.02 ENSRNOT00000020182
secreted frizzled-related protein 5
chr4_+_71675383 0.02 ENSRNOT00000051265
chloride voltage-gated channel 1
chr9_-_61810417 0.02 ENSRNOT00000020910
raftlin family member 2
chr6_-_44363915 0.02 ENSRNOT00000085925
inhibitor of DNA binding 2, HLH protein
chr11_+_80255790 0.02 ENSRNOT00000002522
B-cell CLL/lymphoma 6
chr5_+_24434872 0.02 ENSRNOT00000010696
cyclin E2
chr1_+_88581206 0.02 ENSRNOT00000087931
zinc finger protein 382
chr20_+_2501252 0.02 ENSRNOT00000079307
ENSRNOT00000084559
tripartite motif-containing 39
chr18_-_40134504 0.01 ENSRNOT00000022294
tripartite motif-containing 36
chr11_+_61662270 0.01 ENSRNOT00000079521
zinc finger, DHHC-type containing 23
chr1_-_72468738 0.01 ENSRNOT00000029136
zinc finger protein 628
chr4_-_56114254 0.01 ENSRNOT00000010673
leucine rich repeat containing 4
chr20_+_6351458 0.01 ENSRNOT00000091731
cyclin-dependent kinase inhibitor 1A
chr4_-_100783016 0.01 ENSRNOT00000020671
potassium channel modulatory factor 1
chr9_-_15700235 0.01 ENSRNOT00000088713
ENSRNOT00000035907
transcriptional regulating factor 1
chr10_+_85608544 0.01 ENSRNOT00000092122
MLLT6, PHD finger domain containing
chr10_-_86098694 0.01 ENSRNOT00000067317
F-box and leucine-rich repeat protein 20
chr9_+_47281961 0.01 ENSRNOT00000065234
solute carrier family 9 member A4
chr10_-_88645364 0.01 ENSRNOT00000030344
RAB5C, member RAS oncogene family
chr11_-_59110562 0.01 ENSRNOT00000047907
ENSRNOT00000042024
limbic system-associated membrane protein
chr10_-_73865364 0.00 ENSRNOT00000005226
ribosomal protein S6 kinase B1
chr2_+_60920257 0.00 ENSRNOT00000025170
C1q and tumor necrosis factor related protein 3
chr20_+_2058197 0.00 ENSRNOT00000077774
ENSRNOT00000040634
RT1 class I, locus M6, gene 1
chr13_+_49092306 0.00 ENSRNOT00000000039
NUAK family kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)