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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Twist1

Z-value: 0.20

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Transcription factors associated with Twist1

Gene Symbol Gene ID Gene Info
ENSRNOG00000011101 twist family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Twist1rn6_v1_chr6_+_53401109_534011090.069.2e-01Click!

Activity profile of Twist1 motif

Sorted Z-values of Twist1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_15840990 0.07 ENSRNOT00000015583
iroquois homeobox 3
chr6_-_22281886 0.04 ENSRNOT00000039375
spastin
chr1_-_242152834 0.04 ENSRNOT00000071614
ENSRNOT00000020412
frataxin
chr5_-_24631679 0.03 ENSRNOT00000010846
ENSRNOT00000067129
epithelial splicing regulatory protein 1
chr1_+_80383050 0.03 ENSRNOT00000023451
exocyst complex component 3-like 2
chr8_-_48672732 0.03 ENSRNOT00000079275
hydroxymethylbilane synthase
chr1_-_221431713 0.03 ENSRNOT00000028485
transmembrane 7 superfamily member 2
chr15_+_86153628 0.03 ENSRNOT00000012842
ubiquitin C-terminal hydrolase L3
chr6_-_22281724 0.03 ENSRNOT00000079137
spastin
chr8_+_82560971 0.03 ENSRNOT00000083410
LysM domain containing 2
chr3_+_35271786 0.03 ENSRNOT00000065989
LY6/PLAUR domain containing 6B
chr20_-_2103864 0.03 ENSRNOT00000001014
ring finger protein 39
chr10_+_91187593 0.03 ENSRNOT00000004163
acyl-CoA binding domain containing 4
chr6_+_1657331 0.02 ENSRNOT00000049672
ENSRNOT00000079864
glutaminyl-peptide cyclotransferase
chr10_-_90999506 0.02 ENSRNOT00000034401
glial fibrillary acidic protein
chr10_+_15088935 0.02 ENSRNOT00000030273
G protein subunit gamma 13
chr8_+_82560761 0.02 ENSRNOT00000014301
LysM domain containing 2
chr3_-_51297852 0.02 ENSRNOT00000001607
cordon-bleu WH2 repeat protein-like 1
chr10_+_75032365 0.02 ENSRNOT00000010448
SPT4 homolog, DSIF elongation factor subunit
chr7_-_130120579 0.02 ENSRNOT00000044376
mitogen-activated protein kinase 12
chr9_-_17827032 0.02 ENSRNOT00000026929
solute carrier family 35 member B2
chr9_+_27343853 0.02 ENSRNOT00000072794
transmembrane protein 14A
chr11_+_68198709 0.01 ENSRNOT00000003048
disrupted in renal carcinoma 2
chr7_+_129812789 0.01 ENSRNOT00000006357
cysteine-rich with EGF-like domains 2
chr7_+_141973553 0.01 ENSRNOT00000052075
methyltransferase like 7A
chr5_-_77173502 0.01 ENSRNOT00000023588
solute carrier family 46, member 2
chr8_-_55171718 0.01 ENSRNOT00000080736
hypothetical protein LOC689959
chr3_-_171134655 0.01 ENSRNOT00000028960
similar to Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Ubiquitin thiolesterase L3)
chr18_-_63488027 0.01 ENSRNOT00000023763
protein tyrosine phosphatase, non-receptor type 2
chr3_-_170955399 0.01 ENSRNOT00000084990
bone morphogenetic protein 7
chr20_+_3364814 0.01 ENSRNOT00000001077
hypothetical protein MGC:15854
chr19_-_25261911 0.01 ENSRNOT00000045180
ENSRNOT00000009806
coiled-coil and C2 domain containing 1A
chr1_+_100470722 0.01 ENSRNOT00000086917
aspartate dehydrogenase domain containing
chr19_-_49623758 0.01 ENSRNOT00000071130
polycystic kidney disease 1-like 2
chr3_-_12029877 0.01 ENSRNOT00000022327
solute carrier family 2 member 8
chr3_+_100768637 0.01 ENSRNOT00000083542
brain-derived neurotrophic factor
chr5_+_62071346 0.01 ENSRNOT00000012478
acidic nuclear phosphoprotein 32 family member B
chr1_+_143675985 0.01 ENSRNOT00000078500
transmembrane 6 superfamily member 1
chr3_+_172195844 0.01 ENSRNOT00000034915
aminopeptidase-like 1
chr1_-_100530183 0.01 ENSRNOT00000067754
myosin binding protein C, fast-type
chr3_-_130114770 0.01 ENSRNOT00000010638
jagged 1
chr15_-_3435888 0.01 ENSRNOT00000016709
adenosine kinase
chr10_+_58776792 0.01 ENSRNOT00000019574
thioredoxin domain containing 17
chr18_-_29340403 0.01 ENSRNOT00000025157
heparin-binding EGF-like growth factor
chr5_-_151396507 0.01 ENSRNOT00000012710
G protein-coupled receptor 3
chr1_-_73753128 0.01 ENSRNOT00000068459
tweety family member 1
chr10_+_13000090 0.00 ENSRNOT00000004845
claudin 6
chr4_+_140703619 0.00 ENSRNOT00000009563
basic helix-loop-helix family, member e40
chr7_-_97759852 0.00 ENSRNOT00000007484
derlin 1
chr12_-_6740714 0.00 ENSRNOT00000001205
mesenteric estrogen-dependent adipogenesis
chr7_-_12274803 0.00 ENSRNOT00000049146
APC2, WNT signaling pathway regulator
chr1_+_127802978 0.00 ENSRNOT00000055877
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chrX_+_33599671 0.00 ENSRNOT00000006843
taxilin gamma
chr15_-_33428942 0.00 ENSRNOT00000019618
ENSRNOT00000092160
solute carrier family 7 member 8
chr12_+_17416327 0.00 ENSRNOT00000089590
ENSRNOT00000092186
ArfGAP with dual PH domains 1
chr1_-_72468738 0.00 ENSRNOT00000029136
zinc finger protein 628
chr15_-_45927804 0.00 ENSRNOT00000086271
integrator complex subunit 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Twist1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.0 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)