ISMARA results: Cebpd

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Cebpd

Z-value: 0.58

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Transcription factors associated with Cebpd

Gene Symbol	Gene ID	Gene Info
Cebpd NCBI RGD Ensembl	ENSRNOG00000050869	CCAAT/enhancer binding protein delta

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Cebpd	rn6_v1_chr11_+_89008008_89008008	0.25	6.3e-06	Click!

Activity profile of Cebpd motif

Sorted Z-values of Cebpd motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chrX_+_33443186 Show fit	29.79	ENSRNOT00000005622	S100g NCBI RGD Ensembl Show fit	S100 calcium binding protein G
chr9_-_78969013 Show fit	27.77	ENSRNOT00000019772 ENSRNOT00000057585	Fn1 NCBI RGD Ensembl Show fit	fibronectin 1
chrX_+_143097525 Show fit	22.82	ENSRNOT00000004559	F9 NCBI RGD Ensembl Show fit	coagulation factor IX
chr3_-_121882726 Show fit	21.58	ENSRNOT00000006308	Il1b NCBI RGD Ensembl Show fit	interleukin 1 beta
chr11_-_81717521 Show fit	20.60	ENSRNOT00000058422	Ahsg NCBI RGD Ensembl Show fit	alpha-2-HS-glycoprotein
chr10_-_104628676 Show fit	16.78	ENSRNOT00000010466	Unc13d NCBI RGD Ensembl Show fit	unc-13 homolog D
chr1_+_168964202 Show fit	15.68	ENSRNOT00000089102	LOC103694855 NCBI RGD Ensembl Show fit	hemoglobin subunit beta-2-like
chr1_+_276240703 Show fit	14.96	ENSRNOT00000022126	Acsl5 NCBI RGD Ensembl Show fit	acyl-CoA synthetase long-chain family member 5
chr9_+_8052210 Show fit	14.11	ENSRNOT00000073659	Adgre4 NCBI RGD Ensembl Show fit	adhesion G protein-coupled receptor E4
chr4_-_157155609 Show fit	13.87	ENSRNOT00000016330	C1s NCBI RGD Ensembl Show fit	complement C1s

Showing 1 to 10 of 30 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpd

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
9.3	27.8	GO:2001201	calcium-independent cell-matrix adhesion(GO:0007161) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) regulation of transforming growth factor-beta secretion(GO:2001201)
0.2	22.8	GO:0031638	zymogen activation(GO:0031638)
7.2	21.6	GO:0060559	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.1	20.6	GO:0030502	negative regulation of bone mineralization(GO:0030502)
5.6	16.8	GO:0002432	granuloma formation(GO:0002432)
1.0	15.7	GO:0015671	oxygen transport(GO:0015671)
5.0	15.0	GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
1.0	13.9	GO:0001867	complement activation, lectin pathway(GO:0001867)
3.3	13.4	GO:0097460	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
3.3	13.1	GO:0072592	oxygen metabolic process(GO:0072592)

Showing 1 to 10 of 25 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	53.7	GO:0005615	extracellular space(GO:0005615)
0.3	34.5	GO:0072562	blood microparticle(GO:0072562)
3.5	27.8	GO:0005577	fibrinogen complex(GO:0005577)
0.2	21.6	GO:0005776	autophagosome(GO:0005776)
2.8	16.8	GO:0033093	Weibel-Palade body(GO:0033093)
1.4	15.7	GO:0005833	hemoglobin complex(GO:0005833)
0.1	15.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	14.1	GO:0009986	cell surface(GO:0009986)
2.2	13.4	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
3.2	13.0	GO:0071953	elastic fiber(GO:0071953)

Showing 1 to 10 of 17 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	36.7	GO:0004252	serine-type endopeptidase activity(GO:0004252)
5.0	29.8	GO:0005499	vitamin D binding(GO:0005499)
4.0	27.8	GO:0045340	mercury ion binding(GO:0045340)
1.1	21.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
5.2	20.6	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
0.1	16.8	GO:0017137	Rab GTPase binding(GO:0017137)
1.0	15.7	GO:0005344	oxygen transporter activity(GO:0005344)
1.2	15.0	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
1.7	13.4	GO:1990459	transferrin receptor binding(GO:1990459)
1.1	13.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)

Showing 1 to 10 of 27 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	36.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	29.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
1.3	27.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	24.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
1.4	21.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.4	20.6	PID BMP PATHWAY	BMP receptor signaling
0.3	20.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.5	13.4	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.2	13.0	PID IL12 2PATHWAY	IL12-mediated signaling events

Showing 1 to 9 of 9 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.5	27.8	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
2.3	22.8	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.5	21.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.8	15.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.3	13.9	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.5	13.4	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.3	13.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.5	11.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	9.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.2	4.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle

Showing 1 to 10 of 14 entries

Results for Cebpd

Z-value: 0.58

Motif logo

Transcription factors associated with Cebpd

Activity-expression correlation:

Activity profile of Cebpd motif

Sorted Z-values of Cebpd motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpd

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: