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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Etv6

Z-value: 0.82

Motif logo

Transcription factors associated with Etv6

Gene Symbol Gene ID Gene Info
ENSRNOG00000005984 ets variant 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Etv6rn6_v1_chr4_+_167754525_167754525-0.091.1e-01Click!

Activity profile of Etv6 motif

Sorted Z-values of Etv6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_105355716 11.15 ENSRNOT00000015043
translocase of inner mitochondrial membrane 8 homolog A1 (yeast)
chr8_-_87213627 10.52 ENSRNOT00000066084
cytochrome c oxidase subunit 7A2
chr3_-_79728879 8.73 ENSRNOT00000012425
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr19_+_52032886 6.78 ENSRNOT00000019923
malonyl-CoA decarboxylase
chr10_-_20658100 6.54 ENSRNOT00000010252
arginyl-tRNA synthetase
chr1_-_199395363 6.24 ENSRNOT00000090368
ENSRNOT00000026587
protease, serine, 36
chr4_-_153373649 6.11 ENSRNOT00000016495
ATPase H+ transporting V1 subunit E1
chr9_-_17254949 6.07 ENSRNOT00000026499
mitochondrial ribosomal protein S18A
chr1_-_216953999 5.94 ENSRNOT00000028126
MAS related GPR family member G
chr10_+_55924938 5.87 ENSRNOT00000087003
ENSRNOT00000057079
trafficking protein particle complex 1
chr10_+_75529009 5.82 ENSRNOT00000013771
mitochondrial ribosomal protein S23
chr1_-_264756546 5.69 ENSRNOT00000020020
mitochondrial ribosomal protein L43
chr9_-_23352668 5.51 ENSRNOT00000075279
methylmalonyl CoA mutase
chr7_+_144647587 5.43 ENSRNOT00000022398
homeo box C4
chr10_-_109630005 5.30 ENSRNOT00000075206
oxidoreductase-like domain containing 1
chr1_-_220746224 5.19 ENSRNOT00000027734
barrier to autointegration factor 1
chr13_-_97838228 5.14 ENSRNOT00000003618
transcription factor B2, mitochondrial
chr7_+_97760134 4.96 ENSRNOT00000086792
TBC1 domain family, member 31
chr12_+_52467450 4.86 ENSRNOT00000056675
PGAM family member 5, mitochondrial serine/threonine protein phosphatase
chr17_+_72209373 4.85 ENSRNOT00000064802
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr1_+_225068009 4.78 ENSRNOT00000026651
UBX domain protein 1
chr5_+_137670295 4.65 ENSRNOT00000076672
EBNA1 binding protein 2
chr10_+_75032365 4.49 ENSRNOT00000010448
SPT4 homolog, DSIF elongation factor subunit
chr2_-_189096785 4.47 ENSRNOT00000028200
cholinergic receptor nicotinic beta 2 subunit
chr9_-_16581078 4.44 ENSRNOT00000022582
peroxisomal biogenesis factor 6
chr16_-_7082193 4.44 ENSRNOT00000024447
signal peptidase complex subunit 1
chr8_+_21663325 4.39 ENSRNOT00000027749
ubiquitin-like 5
chr2_-_197982385 4.34 ENSRNOT00000034074
mitochondrial ribosomal protein S21
chr5_+_137458691 4.29 ENSRNOT00000075464
ENSRNOT00000076895
probable rRNA-processing protein EBP2
chr9_+_65478496 4.26 ENSRNOT00000016060
NADH:ubiquinone oxidoreductase subunit B3
chr3_+_125470551 4.21 ENSRNOT00000028898
minichromosome maintenance 8 homologous recombination repair factor
chr20_+_22728208 4.17 ENSRNOT00000000794
nuclear receptor-binding factor 2-like
chr9_+_81672758 4.12 ENSRNOT00000020646
CTD small phosphatase 1
chr8_-_22173797 4.07 ENSRNOT00000042314
ENSRNOT00000079949
cell division cycle 37
chr1_+_218532045 4.04 ENSRNOT00000018848
mitochondrial ribosomal protein L21
chr20_+_13760810 4.04 ENSRNOT00000081140
ENSRNOT00000080203
glutathione S-transferase, theta 2
chr2_-_196046311 4.03 ENSRNOT00000028484
proteasome subunit beta 4
chr7_-_121783435 3.98 ENSRNOT00000034912
ENTH domain containing 1
chr5_+_137670123 3.87 ENSRNOT00000072245
EBNA1 binding protein 2
chr1_+_266358728 3.85 ENSRNOT00000027118
WW domain binding protein 1-like
chrX_+_157095937 3.82 ENSRNOT00000091792
B-cell receptor-associated protein 31
chr8_-_21661259 3.81 ENSRNOT00000068308
F-box and leucine-rich repeat protein 12
chrX_+_27015884 3.81 ENSRNOT00000065814
male-specific lethal 3 homolog (Drosophila)
chr1_-_216942782 3.80 ENSRNOT00000049057
similar to MAS-related G-protein coupled receptor, member G
chr1_-_36112993 3.75 ENSRNOT00000023161
mediator complex subunit 10
chr6_+_108936664 3.62 ENSRNOT00000007298
dihydrolipoamide S-succinyltransferase
chr9_+_82718709 3.56 ENSRNOT00000027256
ENSRNOT00000080524
serine/threonine kinase 11 interacting protein
chr3_-_12007570 3.50 ENSRNOT00000060186
leucine rich repeat and sterile alpha motif containing 1
chr19_-_41433346 3.49 ENSRNOT00000022952
cap methyltransferase 2
chr17_-_29438668 3.42 ENSRNOT00000021660
phenylalanyl-tRNA synthetase 2, mitochondrial
chr19_+_45938915 3.40 ENSRNOT00000065508
MON1 homolog B, secretory trafficking associated
chr8_+_70522092 3.31 ENSRNOT00000025873
dipeptidylpeptidase 8
chr3_+_147713821 3.31 ENSRNOT00000007558
casein kinase 2 alpha 1
chr15_+_24078280 3.27 ENSRNOT00000015511
ENSRNOT00000063807
mitogen-activated protein kinase 1 interacting protein 1-like
chr12_+_8976585 3.27 ENSRNOT00000071796
proteasome maturation protein-like
chr10_-_70516421 3.26 ENSRNOT00000013233
peroxisomal biogenesis factor 12
chr12_-_6784111 3.22 ENSRNOT00000078541

chr12_+_16899025 3.21 ENSRNOT00000001716
proteasome assembly chaperone 3
chr2_+_54897424 3.12 ENSRNOT00000017665
tetratricopeptide repeat domain 33
chr10_+_3321476 3.11 ENSRNOT00000090166
MPV17 mitochondrial inner membrane protein like
chr5_+_142332607 3.10 ENSRNOT00000072841
metal regulatory transcription factor 1-like
chr3_-_125470413 3.10 ENSRNOT00000028893
tRNA methyltransferase 6
chr15_+_28287024 3.07 ENSRNOT00000064907
methyltransferase like 17
chr3_+_151032952 3.06 ENSRNOT00000064013
acyl-CoA synthetase short-chain family member 2
chr19_+_34041219 2.97 ENSRNOT00000017226
transmembrane protein 184C
chr10_+_82375572 2.96 ENSRNOT00000004947
mitochondrial ribosomal protein L27
chr5_-_14588422 2.91 ENSRNOT00000011312
lysophospholipase I
chr3_-_119405300 2.90 ENSRNOT00000015568
signal peptide peptidase-like 2A
chr6_+_75996643 2.87 ENSRNOT00000052076
signal recognition particle 54A
chr9_+_111220858 2.87 ENSRNOT00000076669
diphosphoinositol pentakisphosphate kinase 2
chr5_-_70463546 2.86 ENSRNOT00000043184

chr1_+_226947105 2.84 ENSRNOT00000028373
pre-mRNA processing factor 19
chr5_+_48047913 2.79 ENSRNOT00000065926
LYR motif containing 2
chr12_-_8759599 2.78 ENSRNOT00000073155
proteasome maturation protein
chr12_-_37468935 2.69 ENSRNOT00000001387
DEAD-box helicase 55
chr10_+_84976377 2.66 ENSRNOT00000013114
mitochondrial ribosomal protein L10
chr5_-_138222534 2.62 ENSRNOT00000009691
zinc finger protein 691
chr15_-_55424024 2.59 ENSRNOT00000077733
nudix hydrolase 15
chr7_-_139734568 2.58 ENSRNOT00000079377
ankyrin repeat and SOCS box-containing 8
chr6_-_126636484 2.56 ENSRNOT00000088000
ENSRNOT00000063786
GON7, KEOPS complex subunit homolog
chr1_+_264756499 2.51 ENSRNOT00000031018
progressive external ophthalmoplegia 1
chr11_-_27080701 2.50 ENSRNOT00000002180
listerin E3 ubiquitin protein ligase 1
chr3_+_7422820 2.48 ENSRNOT00000064323
DEAD-box helicase 31
chr5_+_142797366 2.45 ENSRNOT00000031928
metal-regulatory transcription factor 1
chr10_+_109630099 2.32 ENSRNOT00000072099
coiled-coil domain containing 137
chr3_-_140141679 2.32 ENSRNOT00000014632
crooked neck pre-mRNA splicing factor 1
chr6_+_126636662 2.31 ENSRNOT00000010739
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr3_-_7422738 2.31 ENSRNOT00000088339
general transcription factor IIIC subunit 4
chr17_-_90071408 2.30 ENSRNOT00000071978
decaprenyl diphosphate synthase subunit 1
chr7_+_117394372 2.30 ENSRNOT00000048706
glycosylphosphatidylinositol anchor attachment 1
chrX_-_1704033 2.25 ENSRNOT00000051956
ubiquitin specific peptidase 11
chr9_-_111220651 2.24 ENSRNOT00000016028
gypsy retrotransposon integrase 1
chr6_-_102047758 2.22 ENSRNOT00000012101
ATPase H+ transporting V1 subunit D
chr8_+_68526093 2.20 ENSRNOT00000011385
alpha- and gamma-adaptin binding protein
chr5_-_138361702 2.19 ENSRNOT00000067943
ENSRNOT00000064712
peptidylprolyl isomerase H
chr12_+_51937175 2.18 ENSRNOT00000056780
pseudouridylate synthase 1
chr5_-_172488822 2.16 ENSRNOT00000019620
retention in endoplasmic reticulum sorting receptor 1
chr3_-_119405453 2.13 ENSRNOT00000090355
signal peptide peptidase-like 2A
chr19_-_39646693 2.11 ENSRNOT00000019104
proteasome 26S subunit, non-ATPase 7
chr15_+_34270648 2.09 ENSRNOT00000026333
ring finger protein 31
chr17_+_29438980 2.09 ENSRNOT00000072056
LYR motif containing 4
chr10_+_107455845 2.08 ENSRNOT00000004373
C1q and tumor necrosis factor related protein 1
chr16_-_81945127 2.07 ENSRNOT00000023352
MCF.2 cell line derived transforming sequence-like
chr10_-_109639054 2.05 ENSRNOT00000071433
ADP-ribosylation factor like GTPase 16
chr1_+_198911911 2.03 ENSRNOT00000055002
proline rich 14
chr1_-_215290838 2.00 ENSRNOT00000028283
ENSRNOT00000047669
cortactin
chr7_-_12399910 1.99 ENSRNOT00000021677
RGD1562114
chr7_+_74994605 1.97 ENSRNOT00000013801
sperm associated antigen 1
chr2_+_188757489 1.93 ENSRNOT00000028052
pygopus family PHD finger 2
chr1_-_173682226 1.92 ENSRNOT00000020137
RIC3 acetylcholine receptor chaperone
chr12_-_37398329 1.90 ENSRNOT00000083401
tectonic family member 2
chr20_+_3309899 1.89 ENSRNOT00000001049
ATP binding cassette subfamily F member 1
chr15_-_86142672 1.82 ENSRNOT00000057830
COMM domain containing 6
chr4_+_144985880 1.79 ENSRNOT00000009464
THUMP domain containing 3
chr10_+_43768708 1.78 ENSRNOT00000086218
SH3 binding domain protein 5 like
chr1_-_103128743 1.77 ENSRNOT00000075006
SPT2 chromatin protein domain containing 1
chr1_+_29432152 1.75 ENSRNOT00000019436
ENSRNOT00000083276
tRNA methyltransferase 11 homolog
chr6_+_126636491 1.74 ENSRNOT00000089601
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr6_-_105261549 1.70 ENSRNOT00000009122
synaptojanin 2 binding protein
chr2_-_183582553 1.68 ENSRNOT00000014236
ADP-ribosylation factor interacting protein 1
chr19_+_53055745 1.67 ENSRNOT00000074430
forkhead box L1
chr1_+_222250995 1.66 ENSRNOT00000031458
tRNA phosphotransferase 1
chr1_-_102970950 1.63 ENSRNOT00000018194
tumor susceptibility 101
chr10_-_34990943 1.62 ENSRNOT00000075555
required for meiotic nuclear division 5 homolog B
chr1_+_143583675 1.62 ENSRNOT00000026385
family with sequence similarity 103, member A1
chr11_-_24294179 1.61 ENSRNOT00000002116
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chrX_+_115561332 1.60 ENSRNOT00000076680
ENSRNOT00000075912
ENSRNOT00000007968
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr1_-_196884302 1.59 ENSRNOT00000089464
NSE1 homolog, SMC5-SMC6 complex component
chr3_-_21697945 1.57 ENSRNOT00000012433
zinc finger and BTB domain containing 26
chr13_+_44957014 1.55 ENSRNOT00000004878
UBX domain protein 4
chr7_-_2825498 1.54 ENSRNOT00000086656
ENSRNOT00000031362
nucleic acid binding protein 2
chr1_-_101426852 1.54 ENSRNOT00000028217
RuvB-like AAA ATPase 2
chr1_-_226255886 1.53 ENSRNOT00000027842
flap structure-specific endonuclease 1
chr10_-_37209881 1.51 ENSRNOT00000090475
SEC24 homolog A, COPII coat complex component
chr16_+_7082450 1.49 ENSRNOT00000013291
glycosyltransferase 8 domain containing 1
chr7_-_33584564 1.47 ENSRNOT00000005463
neural precursor cell expressed, developmentally down-regulated 1
chr10_-_67285617 1.47 ENSRNOT00000019044
UTP6 small subunit processome component
chr2_+_263864331 1.45 ENSRNOT00000055259
zinc finger RANBP2-type containing 2
chr1_+_80056755 1.44 ENSRNOT00000021221
small nuclear ribonucleoprotein D2 polypeptide
chr3_+_21698032 1.44 ENSRNOT00000013378
RAB GTPase activating protein 1
chr10_+_93354003 1.43 ENSRNOT00000008140
methyltransferase like 2B
chr18_-_40732126 1.42 ENSRNOT00000000170
autophagy related 12
chr5_+_47186558 1.42 ENSRNOT00000007654
mitogen-activated protein kinase kinase kinase 7-like
chr4_-_59014416 1.39 ENSRNOT00000049811
similar to 60S ribosomal protein L38
chr1_+_147021436 1.38 ENSRNOT00000042490
coagulation factor VIII-associated 1
chr15_-_34352673 1.37 ENSRNOT00000064916
neural precursor cell expressed, developmentally down-regulated 8
chr20_-_5112872 1.35 ENSRNOT00000076983
ENSRNOT00000001123
ENSRNOT00000076528
casein kinase 2 beta
chr12_+_23989596 1.35 ENSRNOT00000001960
transmembrane protein 120A
chr19_-_39257451 1.33 ENSRNOT00000066312
component of oligomeric golgi complex 8
chr13_+_85465792 1.32 ENSRNOT00000082991
ENSRNOT00000005277
transmembrane and coiled-coil domains 1
chr10_-_35716260 1.31 ENSRNOT00000004308
ENSRNOT00000059255
sequestosome 1
chr2_-_62887048 1.29 ENSRNOT00000039234
similar to hypothetical protein FLJ11193
chr9_-_42805673 1.23 ENSRNOT00000020558
UDP-glucose glycoprotein glucosyltransferase 1
chr10_-_108425206 1.22 ENSRNOT00000073140
eukaryotic translation initiation factor 4A3
chr6_+_129609375 1.20 ENSRNOT00000083732
poly (A) polymerase alpha
chr3_+_110918243 1.19 ENSRNOT00000056432
RAD51 recombinase
chr7_+_12256387 1.19 ENSRNOT00000021939
similar to RIKEN cDNA 2310011J03
chr13_+_56513286 1.14 ENSRNOT00000015596
zinc finger and BTB domain containing 41
chr3_+_122947913 1.12 ENSRNOT00000028821
VPS16 CORVET/HOPS core subunit
chr14_-_104375649 1.12 ENSRNOT00000006607
ARP2 actin related protein 2 homolog
chr1_+_60717386 1.10 ENSRNOT00000015019
protein phosphatase 2 scaffold subunit A alpha
chr4_-_145699577 1.10 ENSRNOT00000014377
SEC13 homolog, nuclear pore and COPII coat complex component
chr9_+_114022137 1.08 ENSRNOT00000007657
mitogen activated protein kinase kinase kinase 7
chr6_+_10594122 1.07 ENSRNOT00000020534
CXXC repeat containing interactor of PDZ3 domain
chr1_-_217638118 1.07 ENSRNOT00000054859
ENSRNOT00000092916
cortactin
chr3_+_11554457 1.06 ENSRNOT00000073087
family with sequence similarity 102, member A
chr8_+_49354115 1.05 ENSRNOT00000032837
myelin protein zero-like 3
chr10_-_94445503 1.04 ENSRNOT00000013295
FtsJ homolog 3
chr1_+_31700953 1.04 ENSRNOT00000020251
exocyst complex component 3
chr13_-_37287458 1.03 ENSRNOT00000003391
insulin induced gene 2
chr12_+_11240761 1.02 ENSRNOT00000001310
PDGFA associated protein 1
chrX_-_70461553 1.01 ENSRNOT00000076110
ENSRNOT00000003872
ENSRNOT00000076812
PDZ domain containing 11
chr10_+_28243 1.00 ENSRNOT00000003193
ENSRNOT00000087156
meiosis arrest female protein 1-like
chr4_-_157486844 0.99 ENSRNOT00000038281
ENSRNOT00000022874
COP9 signalosome subunit 7A
chr4_-_7113919 0.98 ENSRNOT00000014082
chondroitin polymerizing factor 2
chr2_+_189400696 0.91 ENSRNOT00000046919
ENSRNOT00000089801
similar to NICE-3
chr3_-_94419048 0.91 ENSRNOT00000015775
homeodomain interacting protein kinase 3
chr10_+_94445877 0.90 ENSRNOT00000013997
proteasome 26S subunit, ATPase 5
chr5_+_126226291 0.89 ENSRNOT00000009582
tetratricopeptide repeat domain 22
chr1_-_170586603 0.86 ENSRNOT00000025955
TATA-box binding protein associated factor 10
chr5_-_134348995 0.84 ENSRNOT00000015961
fatty acid amide hydrolase
chr6_+_108796182 0.84 ENSRNOT00000006297
FCF1 rRNA-processing protein
chr1_-_218532118 0.83 ENSRNOT00000086385
ENSRNOT00000018487
immunoglobulin mu binding protein 2
chr8_-_21968415 0.82 ENSRNOT00000067325
ENSRNOT00000064932
DNA methyltransferase 1
chr10_+_48773828 0.82 ENSRNOT00000004113
phosphatidylinositol glycan anchor biosynthesis, class L
chr1_+_65541322 0.82 ENSRNOT00000030931
charged multivesicular body protein 2A
chr1_+_197839430 0.81 ENSRNOT00000025043
rabaptin, RAB GTPase binding effector protein 2
chr10_-_109802739 0.80 ENSRNOT00000054951
sirtuin 7
chr19_+_30668602 0.79 ENSRNOT00000035084
ubiquitin specific peptidase 38
chr1_-_80515694 0.79 ENSRNOT00000075144
CLK4-associating serine/arginine rich protein
chr19_+_39257586 0.78 ENSRNOT00000027653
NIP7, nucleolar pre-rRNA processing protein
chr2_-_58534211 0.75 ENSRNOT00000089178
S-phase kinase associated protein 2
chr2_+_165805144 0.72 ENSRNOT00000073716
RAB interacting factor
chr7_-_2972521 0.72 ENSRNOT00000061995
zinc finger CCCH type containing 10
chr7_-_97759852 0.72 ENSRNOT00000007484
derlin 1
chr8_-_62542622 0.71 ENSRNOT00000080071
CDC-like kinase 3
chr10_-_37084637 0.70 ENSRNOT00000075525
protein RMD5 homolog B
chr16_+_18975746 0.69 ENSRNOT00000066121
small integral membrane protein 7
chrX_-_112328642 0.68 ENSRNOT00000083150
proteasome 26S subunit, non-ATPase 10
chr9_-_81880105 0.66 ENSRNOT00000022677
ring finger protein 25

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0036115 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) fatty-acyl-CoA catabolic process(GO:0036115)
1.8 5.4 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
1.6 6.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
1.5 4.5 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
1.3 4.0 GO:0009751 response to salicylic acid(GO:0009751)
1.3 5.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
1.3 3.8 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
1.2 7.4 GO:0015074 DNA integration(GO:0015074)
1.2 3.6 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
1.2 4.8 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
1.2 3.5 GO:0036451 cap mRNA methylation(GO:0036451)
1.1 3.4 GO:0019086 late viral transcription(GO:0019086)
1.1 4.4 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
1.0 3.1 GO:0006083 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
0.8 3.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.7 2.9 GO:0002084 protein depalmitoylation(GO:0002084)
0.7 2.8 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.6 3.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.6 1.8 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.6 7.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.6 1.7 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.5 2.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.5 2.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.5 2.6 GO:0006203 dGTP catabolic process(GO:0006203) DNA protection(GO:0042262)
0.5 1.5 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.5 2.3 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.5 5.0 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.4 4.5 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.4 1.2 GO:0072714 response to selenite ion(GO:0072714) regulation of selenocysteine incorporation(GO:1904569)
0.4 1.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.4 6.7 GO:0043248 proteasome assembly(GO:0043248)
0.4 2.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.4 3.1 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.4 1.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 4.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.3 5.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.3 1.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.3 1.2 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106) replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.3 6.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.3 1.9 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.3 3.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 1.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 2.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.2 3.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 6.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 1.1 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 1.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 0.8 GO:0010424 DNA methylation on cytosine within a CG sequence(GO:0010424) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 0.8 GO:0061511 centriole elongation(GO:0061511)
0.2 0.6 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 4.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2 14.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 8.7 GO:0032543 mitochondrial translation(GO:0032543)
0.2 9.3 GO:0021762 substantia nigra development(GO:0021762)
0.2 1.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 0.6 GO:0031053 primary miRNA processing(GO:0031053)
0.2 4.9 GO:0070266 necroptotic process(GO:0070266)
0.2 1.4 GO:0006983 ER overload response(GO:0006983)
0.2 2.9 GO:0006020 inositol metabolic process(GO:0006020)
0.2 1.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 1.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 2.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.8 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 1.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.4 GO:0033123 positive regulation of purine nucleotide catabolic process(GO:0033123) positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.1 1.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.7 GO:1903671 negative regulation of activin receptor signaling pathway(GO:0032926) negative regulation of sprouting angiogenesis(GO:1903671)
0.1 5.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.3 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) regulation of progesterone biosynthetic process(GO:2000182)
0.1 8.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 0.9 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.8 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 1.0 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.6 GO:0006449 regulation of translational termination(GO:0006449)
0.1 1.5 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.1 1.0 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 1.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.0 GO:0051601 exocyst localization(GO:0051601)
0.1 1.4 GO:0045116 protein neddylation(GO:0045116)
0.1 4.3 GO:0022900 electron transport chain(GO:0022900)
0.1 1.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 2.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 2.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 0.3 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 1.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 1.6 GO:0006301 postreplication repair(GO:0006301)
0.1 3.3 GO:0097421 liver regeneration(GO:0097421)
0.1 2.2 GO:0061512 protein localization to cilium(GO:0061512)
0.1 4.1 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 5.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 0.9 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 0.2 GO:0016246 RNA interference(GO:0016246)
0.1 0.8 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 1.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 1.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 5.5 GO:0007292 female gamete generation(GO:0007292)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 2.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 2.5 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 1.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 3.7 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 1.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 3.8 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 1.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.8 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.5 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 2.1 GO:0016579 protein deubiquitination(GO:0016579)
0.0 2.0 GO:0007338 single fertilization(GO:0007338)
0.0 1.4 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.3 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 1.0 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 2.7 GO:0032259 methylation(GO:0032259)
0.0 0.8 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
1.1 4.5 GO:0032044 DSIF complex(GO:0032044)
1.1 3.3 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
1.0 3.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
1.0 3.8 GO:0072487 MSL complex(GO:0072487)
0.9 2.8 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.8 3.8 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.7 2.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.7 3.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.7 5.0 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.6 3.7 GO:0070847 core mediator complex(GO:0070847)
0.6 4.8 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.6 2.3 GO:0034657 GID complex(GO:0034657)
0.5 4.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.5 3.1 GO:0099571 postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
0.5 6.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.5 5.9 GO:0030008 TRAPP complex(GO:0030008)
0.5 13.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 6.1 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.4 2.1 GO:0071797 LUBAC complex(GO:0071797)
0.4 1.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.4 1.5 GO:0070876 SOSS complex(GO:0070876)
0.4 2.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.4 4.2 GO:0042555 MCM complex(GO:0042555)
0.4 10.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.4 2.9 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.4 1.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.3 1.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 6.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 2.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.3 15.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 1.5 GO:0097255 R2TP complex(GO:0097255)
0.3 13.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 8.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.2 4.1 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.2 1.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.2 0.7 GO:0048500 signal recognition particle(GO:0048500)
0.2 4.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 1.9 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.1 GO:0030478 actin cap(GO:0030478)
0.2 1.6 GO:0000813 ESCRT I complex(GO:0000813)
0.2 3.7 GO:0005838 proteasome regulatory particle(GO:0005838)
0.2 3.8 GO:0005839 proteasome core complex(GO:0005839)
0.2 11.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 7.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 1.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.9 GO:0000125 PCAF complex(GO:0000125)
0.1 1.1 GO:0033263 CORVET complex(GO:0033263)
0.1 1.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.5 GO:0044754 autolysosome(GO:0044754)
0.1 0.4 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.1 1.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 4.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.8 GO:0032797 SMN complex(GO:0032797)
0.1 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.5 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.2 GO:0000800 lateral element(GO:0000800)
0.1 5.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 4.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 4.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 6.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 4.9 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.2 GO:0044452 nucleolar part(GO:0044452)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 3.5 GO:0034702 ion channel complex(GO:0034702)
0.0 2.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.6 6.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618)
1.2 3.6 GO:0016748 succinyltransferase activity(GO:0016748)
1.2 3.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
1.0 4.8 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.9 2.6 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.8 5.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.8 3.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.7 2.9 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.7 2.9 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829)
0.7 5.5 GO:0031419 cobalamin binding(GO:0031419)
0.7 4.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.7 6.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.6 1.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.5 4.4 GO:0031386 protein tag(GO:0031386)
0.5 3.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.5 4.9 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 1.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 2.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4 2.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923) GPI anchor binding(GO:0034235)
0.4 1.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.3 8.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 1.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523) 5'-flap endonuclease activity(GO:0017108)
0.3 0.9 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.3 8.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 0.8 GO:0004040 amidase activity(GO:0004040)
0.3 3.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 4.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 4.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 2.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 4.1 GO:0043422 protein kinase B binding(GO:0043422)
0.2 1.9 GO:0008494 translation activator activity(GO:0008494)
0.2 5.4 GO:0071837 HMG box domain binding(GO:0071837)
0.2 4.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 3.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 4.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 1.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 0.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 1.2 GO:0000150 recombinase activity(GO:0000150)
0.2 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 4.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 1.6 GO:0046790 virion binding(GO:0046790)
0.2 1.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 4.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 7.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 1.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 0.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 1.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 2.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 5.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.0 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 2.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 21.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 5.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 4.2 GO:0004386 helicase activity(GO:0004386)
0.1 3.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 4.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 3.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 2.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 9.8 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 3.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 5.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 6.7 GO:0042623 ATPase activity, coupled(GO:0042623)
0.0 1.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 2.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.8 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.3 GO:0051378 serotonin binding(GO:0051378)
0.0 1.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.2 GO:0042393 histone binding(GO:0042393)
0.0 8.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.5 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.3 GO:0005262 calcium channel activity(GO:0005262)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 4.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 3.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.1 PID MYC PATHWAY C-MYC pathway
0.1 1.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 0.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.3 PID ATR PATHWAY ATR signaling pathway
0.0 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.0 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.4 6.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.4 5.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4 4.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 3.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 4.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 4.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 8.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 1.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 6.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 3.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 3.4 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.2 11.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 1.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 7.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.5 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 2.9 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 2.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 0.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.7 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 5.1 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 1.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 2.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 1.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.8 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 3.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 6.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules