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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Glis2

Z-value: 0.90

Motif logo

Transcription factors associated with Glis2

Gene Symbol Gene ID Gene Info
ENSRNOG00000004766 GLIS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Glis2rn6_v1_chr10_-_11174861_11174861-0.256.2e-06Click!

Activity profile of Glis2 motif

Sorted Z-values of Glis2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_30791422 31.99 ENSRNOT00000047394
ENSRNOT00000000683
thymus, brain and testes associated
chr14_-_78377825 23.71 ENSRNOT00000068104

chr6_-_138250089 19.45 ENSRNOT00000048378
immunoglobulin heavy constant mu
chr12_+_9360672 16.93 ENSRNOT00000088957
fms-related tyrosine kinase 3
chr20_-_1980101 16.13 ENSRNOT00000084582
ENSRNOT00000085050
ENSRNOT00000082545
ENSRNOT00000088396
gamma-aminobutyric acid type B receptor subunit 1
chr7_-_119768082 15.82 ENSRNOT00000009612
somatostatin receptor 3
chr12_+_25119355 15.79 ENSRNOT00000034629
linker for activation of T cells family, member 2
chr15_-_54906203 15.62 ENSRNOT00000020186
cysteinyl leukotriene receptor 2
chr17_-_44840131 15.34 ENSRNOT00000083417
histone cluster 1, H3b
chr3_+_148579920 15.02 ENSRNOT00000012432
HCK proto-oncogene, Src family tyrosine kinase
chr10_+_91710495 14.41 ENSRNOT00000033276
reprimo-like
chr16_-_14348046 14.39 ENSRNOT00000018630
cadherin-related family member 1
chr9_-_54484533 14.27 ENSRNOT00000083514
signal transducer and activator of transcription 1
chr7_+_70364813 13.21 ENSRNOT00000084012
ENSRNOT00000031230
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr10_-_57436368 12.23 ENSRNOT00000056608
SLP adaptor and CSK interacting membrane protein
chr10_+_88490798 11.67 ENSRNOT00000023872
2',3'-cyclic nucleotide 3' phosphodiesterase
chr6_-_137664133 11.58 ENSRNOT00000018613
G protein-coupled receptor 132
chr7_-_143552588 10.94 ENSRNOT00000086317
ENSRNOT00000092619
ENSRNOT00000092138
keratin 78
chr14_-_28856214 10.65 ENSRNOT00000044659
adhesion G protein-coupled receptor L3
chr11_+_60073383 10.47 ENSRNOT00000087508
transgelin 3
chr19_+_50045020 10.40 ENSRNOT00000090165
phospholipase C, gamma 2
chr15_+_34187223 9.95 ENSRNOT00000024978
copine 6
chr11_+_60336061 9.53 ENSRNOT00000084022
similar to OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen)
chr4_-_113866674 9.51 ENSRNOT00000010020
docking protein 1
chr4_-_103145058 9.47 ENSRNOT00000073076

chr11_+_57505005 9.40 ENSRNOT00000002942
transgelin-3
chr4_-_58006839 9.25 ENSRNOT00000076645
centrosomal protein 41
chr18_-_24057917 9.16 ENSRNOT00000023874
Ras-like without CAAX 2
chr10_-_88551056 9.14 ENSRNOT00000032737
zinc finger protein 385C
chr4_+_147333056 9.06 ENSRNOT00000012137
peroxisome proliferator-activated receptor gamma
chr12_+_25036605 9.04 ENSRNOT00000001996
ENSRNOT00000084427
LIM domain kinase 1
chrX_+_28593405 9.00 ENSRNOT00000071708
thymosin beta 4, X-linked
chr4_-_179307095 8.92 ENSRNOT00000021193
branched chain amino acid transaminase 1
chr1_+_199196059 8.84 ENSRNOT00000090428
F-box and leucine-rich repeat protein 19
chr13_+_70174936 8.82 ENSRNOT00000064068
ENSRNOT00000079861
ENSRNOT00000092562
actin related protein 2/3 complex, subunit 5
chr7_+_143629455 8.72 ENSRNOT00000073951
keratin 18
chr14_+_25589762 8.40 ENSRNOT00000043938
ENSRNOT00000067439
ENSRNOT00000002793
EPH receptor A5
chr13_+_48455923 8.20 ENSRNOT00000009280
Rab7b, member RAS oncogene family
chr15_-_33725188 8.19 ENSRNOT00000083941
zinc finger homeobox 2
chr1_+_124625985 7.97 ENSRNOT00000021068
OTU deubiquitinase 7A
chr8_+_133197032 7.96 ENSRNOT00000075564
chemokine (C-C motif) receptor 5
chr1_+_82480195 7.90 ENSRNOT00000028051
transforming growth factor, beta 1
chr4_+_161685258 7.74 ENSRNOT00000008012
ENSRNOT00000008003
forkhead box M1
chr20_-_2678141 7.70 ENSRNOT00000072377
ENSRNOT00000083833
complement component 4A (Rodgers blood group)
chr11_-_60882379 7.60 ENSRNOT00000002799
CD200 receptor 1
chr20_-_4070721 7.55 ENSRNOT00000000523
RT1 class II, locus Ba
chr1_-_212022212 7.40 ENSRNOT00000074298
cilia and flagella associated protein 46
chr7_-_116255167 7.33 ENSRNOT00000038109
ENSRNOT00000041774
cytochrome P450, family 11, subfamily b, polypeptide 2
chr20_-_4508197 7.24 ENSRNOT00000086027
ENSRNOT00000000514
complement component 4A (Rodgers blood group)
chr7_-_123445613 7.16 ENSRNOT00000070937
shisa family member 8
chr19_+_37305248 7.04 ENSRNOT00000068299
solute carrier family 9 member A5
chr2_-_178057157 6.92 ENSRNOT00000091135
Rap guanine nucleotide exchange factor 2
chr17_+_80882666 6.80 ENSRNOT00000024430
vimentin
chr20_-_4316715 6.78 ENSRNOT00000031704
complement C4B (Chido blood group)
chr12_+_23544287 6.78 ENSRNOT00000001938
ORAI calcium release-activated calcium modulator 2
chr16_+_2743823 6.67 ENSRNOT00000087873
Rho guanine nucleotide exchange factor 3
chr1_-_219719272 6.58 ENSRNOT00000026152
synaptotagmin 12
chr7_-_28040510 6.58 ENSRNOT00000005674
achaete-scute family bHLH transcription factor 1
chr2_-_93985378 6.54 ENSRNOT00000075493
fatty acid binding protein 5, epidermal
chr1_+_100832324 6.53 ENSRNOT00000056364
interleukin 4 induced 1
chr10_+_107455845 6.52 ENSRNOT00000004373
C1q and tumor necrosis factor related protein 1
chrX_-_78496847 6.45 ENSRNOT00000003265
integral membrane protein 2A
chr3_+_148773259 6.39 ENSRNOT00000013804
kinesin family member 3B
chr1_-_73619356 6.19 ENSRNOT00000074352
leukocyte immunoglobulin like receptor B3
chr6_-_33738825 6.13 ENSRNOT00000039492
solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr7_-_143956668 5.95 ENSRNOT00000018809
aladin WD repeat nucleoporin
chr9_+_81656116 5.77 ENSRNOT00000083421
solute carrier family 11 member 1
chr2_+_5437067 5.73 ENSRNOT00000093516
POU domain class 5, transcription factor 2
chr11_+_60072727 5.61 ENSRNOT00000090230
transgelin 3
chr11_+_45751812 5.47 ENSRNOT00000079336
similar to Dermal papilla derived protein 7
chr10_+_61403130 5.35 ENSRNOT00000092490
ENSRNOT00000077649
coiled-coil domain containing 92B
chrX_-_10031167 5.13 ENSRNOT00000060988
G protein-coupled receptor 34
chr6_+_123897956 5.13 ENSRNOT00000005167
tyrosyl-DNA phosphodiesterase 1
chr8_+_21890319 5.01 ENSRNOT00000027949
hypothetical protein LOC500956
chr7_+_11737293 4.76 ENSRNOT00000046059
leucine rich repeat and Ig domain containing 3
chr14_+_34389991 4.74 ENSRNOT00000002953
phosducin-like 2
chr5_-_160555083 4.65 ENSRNOT00000018953
forkhead associated phosphopeptide binding domain 1
chr3_+_147042944 4.58 ENSRNOT00000012608
FK506 binding protein 1a
chr12_+_42097626 4.56 ENSRNOT00000001893
T-box 5
chr3_-_143063983 4.42 ENSRNOT00000006329
NSF attachment protein beta
chr10_-_70506963 4.38 ENSRNOT00000076883
ENSRNOT00000012874
schlafen family member 14
chr8_+_117574161 4.31 ENSRNOT00000077078
inositol hexakisphosphate kinase 2
chr3_+_11756384 4.22 ENSRNOT00000087762
SH2 domain containing 3C
chr3_+_2506426 4.22 ENSRNOT00000015242
leucine rich repeat containing 26
chr3_-_114074803 4.20 ENSRNOT00000022964
PAT1 homolog 2
chr8_-_116532169 4.17 ENSRNOT00000085364
RNA binding motif protein 5
chr12_+_22229079 4.16 ENSRNOT00000001911
G protein subunit beta 2
chr12_+_22466601 4.03 ENSRNOT00000074544

chr16_-_3762877 4.02 ENSRNOT00000052224
double homeobox B-like 1
chr16_-_18860086 3.97 ENSRNOT00000074814
SIN3 transcription regulator family member B
chr20_+_28572242 3.95 ENSRNOT00000072485
SH3 domain containing ring finger 3
chr9_+_16702460 3.88 ENSRNOT00000061432
protein tyrosine kinase 7
chr14_-_6533524 3.81 ENSRNOT00000079795
ATP-binding cassette, subfamily G (WHITE), member 3-like 1
chr14_-_35149608 3.78 ENSRNOT00000003050
ENSRNOT00000090654
KIT proto-oncogene receptor tyrosine kinase
chrX_+_71324365 3.76 ENSRNOT00000004911
non-POU domain containing, octamer-binding
chr20_-_17091766 3.73 ENSRNOT00000074404
ZW10 interacting kinetochore protein
chr3_+_80556668 3.66 ENSRNOT00000079118
Rho GTPase activating protein 1
chr12_-_2387930 3.62 ENSRNOT00000031997
CD209e molecule
chr5_-_151709877 3.61 ENSRNOT00000080602
TMF1-regulated nuclear protein 1
chr20_-_2212171 3.54 ENSRNOT00000085912
tripartite motif-containing 26
chr12_-_47456894 3.50 ENSRNOT00000001570
2'-5'-oligoadenylate synthetase-like
chr9_+_12740885 3.48 ENSRNOT00000015210
raftlin lipid raft linker 1
chr15_-_11912806 3.42 ENSRNOT00000068171
ENSRNOT00000008759
ENSRNOT00000049771
solute carrier family 4 member 7
chrX_-_123515720 3.35 ENSRNOT00000092343
NFKB repressing factor
chr10_+_20591432 3.32 ENSRNOT00000059780
pantothenate kinase 3
chr11_-_77593171 3.17 ENSRNOT00000002645
ENSRNOT00000043498
interleukin 1 receptor accessory protein
chr14_+_11095163 3.14 ENSRNOT00000003076
transmembrane protein 150C
chr2_+_189106039 3.06 ENSRNOT00000028210
ubiquitin conjugating enzyme E2 Q1
chr1_+_85162452 3.01 ENSRNOT00000093347
p21 (RAC1) activated kinase 4
chr1_-_219853329 3.00 ENSRNOT00000026169
leucine rich repeat and fibronectin type III domain containing 4
chr1_-_175676699 2.87 ENSRNOT00000030474
lymphatic vessel endothelial hyaluronan receptor 1
chr16_-_7007287 2.81 ENSRNOT00000041216
inter-alpha trypsin inhibitor, heavy chain 3
chr10_-_37311625 2.75 ENSRNOT00000043343
jade family PHD finger 2
chr20_+_17750744 2.72 ENSRNOT00000000745
similar to RIKEN cDNA 1700049L16
chr8_+_130581062 2.71 ENSRNOT00000014323
family with sequence similarity 198, member A
chr8_+_116754178 2.65 ENSRNOT00000068295
ENSRNOT00000084429
ubiquitin-like modifier activating enzyme 7
chr7_-_30274984 2.65 ENSRNOT00000092527
ENSRNOT00000010207
solute carrier family 17 member 8
chr10_-_87529599 2.63 ENSRNOT00000074099
keratin associated protein 2-1
chr18_+_30114708 2.55 ENSRNOT00000027343
protocadherin alpha 4
chr17_+_23135985 2.52 ENSRNOT00000090794
neural precursor cell expressed, developmentally down-regulated 9
chr6_-_107080524 2.51 ENSRNOT00000011662
zinc finger FYVE-type containing 1
chr14_-_6369666 2.51 ENSRNOT00000093293
ENSRNOT00000093262
zinc finger protein 951
chrX_-_82986051 2.50 ENSRNOT00000077587
highly divergent homeobox
chr7_-_12601674 2.50 ENSRNOT00000093489
AT-rich interaction domain 3A
chr7_-_129724303 2.45 ENSRNOT00000006034
bromodomain containing 1
chr2_-_188645196 2.40 ENSRNOT00000083793
ephrin A3
chr12_-_38782010 2.36 ENSRNOT00000001813
WD repeat domain 66
chr1_-_1474846 2.36 ENSRNOT00000028992
retinoic acid early transcript delta
chr9_-_81565416 2.29 ENSRNOT00000083582
angio-associated, migratory cell protein
chr20_-_2211995 2.29 ENSRNOT00000077201
tripartite motif-containing 26
chr4_+_27175243 2.28 ENSRNOT00000009985
cytochrome P450, family 51
chr1_-_127292090 2.13 ENSRNOT00000016959
leucine-rich repeat kinase 1
chr10_-_57309298 2.12 ENSRNOT00000056622
calmodulin binding transcription activator 2
chr1_+_166564664 2.10 ENSRNOT00000090959
phosphodiesterase 2A
chr7_-_12311149 2.07 ENSRNOT00000046886
DAZ associated protein 1
chrX_+_65226748 2.06 ENSRNOT00000076181
moesin
chr7_-_115045802 2.00 ENSRNOT00000040236
ENSRNOT00000071818
maestro heat-like repeat family member 5
chr11_+_68493035 1.96 ENSRNOT00000067984
protein disulfide isomerase family A, member 5
chr15_+_19603288 1.96 ENSRNOT00000035491
REST corepressor 2-like
chr20_-_7930929 1.92 ENSRNOT00000000607
TEA domain transcription factor 3
chr7_-_70476340 1.90 ENSRNOT00000006800
Rho guanine nucleotide exchange factor 25
chr10_+_43538160 1.85 ENSRNOT00000089217
CCR4-NOT transcription complex, subunit 8
chr4_+_113910685 1.84 ENSRNOT00000011173
polycomb group RING finger protein 1
chr8_+_129201669 1.77 ENSRNOT00000025663
ectonucleoside triphosphate diphosphohydrolase 3
chr1_-_184188911 1.76 ENSRNOT00000055124
ENSRNOT00000014948
calcitonin-related polypeptide alpha
chr19_-_29802083 1.67 ENSRNOT00000024755

chr1_-_101596822 1.62 ENSRNOT00000028490
fibroblast growth factor 21
chr6_+_129052503 1.61 ENSRNOT00000044152
similar to BC049975 protein
chr7_+_114724610 1.60 ENSRNOT00000014541
DENN domain containing 3
chrX_+_115563038 1.54 ENSRNOT00000087859
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr12_+_31934343 1.52 ENSRNOT00000011181
transmembrane protein 132D
chr17_-_1093873 1.52 ENSRNOT00000086130
patched 1
chr1_+_123015746 1.51 ENSRNOT00000013483
MAGE family member L2
chr4_+_114776797 1.49 ENSRNOT00000089635
polycomb group RING finger protein 1
chr1_-_170471076 1.43 ENSRNOT00000025159
ADP-ribosylation factor interacting protein 2
chr19_+_39063998 1.42 ENSRNOT00000081116
hyaluronan synthase 3
chr1_-_98490315 1.38 ENSRNOT00000056490
claudin domain containing 2
chr10_+_40553180 1.37 ENSRNOT00000087763
solute carrier family 36 member 1
chr15_+_57505449 1.36 ENSRNOT00000064945
siah E3 ubiquitin protein ligase family member 3
chr17_+_89742140 1.34 ENSRNOT00000077899
microtubule associated serine/threonine kinase-like
chr5_-_64674250 1.29 ENSRNOT00000089232
acyl-coenzyme A amino acid N-acyltransferase 2
chr10_-_49196177 1.28 ENSRNOT00000084418
zinc finger protein 286A
chr15_+_34520142 1.21 ENSRNOT00000074659
NYN domain and retroviral integrase containing
chr12_-_47793534 1.13 ENSRNOT00000001588
family with sequence similarity 222, member A
chr13_-_89661150 1.12 ENSRNOT00000058390
ubiquitin specific peptidase 21
chr6_-_107325345 1.11 ENSRNOT00000049481
ENSRNOT00000042594
ENSRNOT00000013026
NUMB, endocytic adaptor protein
chr5_-_144436509 1.09 ENSRNOT00000042371
argonaute 3, RISC catalytic component
chr11_-_89260297 1.08 ENSRNOT00000057502
scaffolding protein involved in DNA repair
chr3_-_148312791 1.08 ENSRNOT00000091419
Bcl2-like 1
chr8_+_132120452 1.06 ENSRNOT00000055822
transglutaminase 4
chr1_-_213745748 1.05 ENSRNOT00000020023
interferon induced transmembrane protein 5
chr1_+_177193735 1.04 ENSRNOT00000043017
MICAL C-terminal like
chr3_+_149424392 1.04 ENSRNOT00000044574
BPI fold containing family B, member 4
chr3_-_72289310 1.03 ENSRNOT00000038250
reticulon 4 receptor-like 2
chr10_-_70202398 1.03 ENSRNOT00000076089
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr3_+_143119687 1.01 ENSRNOT00000006608
cystatin 12
chr9_-_19372673 0.99 ENSRNOT00000073667
ENSRNOT00000079517
chloride intracellular channel 5
chr20_+_5442390 0.96 ENSRNOT00000037499
ribosomal protein S18
chr20_-_10257044 0.95 ENSRNOT00000068289
WD repeat domain 4
chr10_+_72486152 0.91 ENSRNOT00000004193
similar to Chromodomain-helicase-DNA-binding protein 1 (CHD-1)
chr10_-_75120247 0.90 ENSRNOT00000011402
lactoperoxidase
chr10_+_35637133 0.90 ENSRNOT00000043085
TBC1 domain family member 9B
chr4_-_7885301 0.89 ENSRNOT00000035034
RAD50 interactor 1
chr3_-_93734282 0.86 ENSRNOT00000012428
cell cycle associated protein 1
chr16_-_23156962 0.82 ENSRNOT00000018543
SH2 domain containing 4A
chr2_+_196139755 0.80 ENSRNOT00000040501
phosphatidylinositol 4-kinase beta
chr11_+_54137639 0.79 ENSRNOT00000066343
leukocyte surface antigen CD47-like
chr16_-_2048292 0.75 ENSRNOT00000061883
zinc finger CCHC-type containing 24
chr3_-_176865103 0.74 ENSRNOT00000019038
ADP-ribosylation factor related protein 1
chr1_-_83418777 0.73 ENSRNOT00000049175
cytochrome P450, family 2, subfamily b, polypeptide 21
chr10_-_85938085 0.72 ENSRNOT00000043561
plexin domain containing 1
chr19_-_52750307 0.70 ENSRNOT00000023405
zinc finger, DHHC-type containing 7
chrX_+_65566047 0.69 ENSRNOT00000092103
hephaestin
chr17_+_56935451 0.67 ENSRNOT00000058966
similar to hypothetical protein 4930474N05
chr6_-_25507073 0.67 ENSRNOT00000061176
phospholipase B1
chr3_-_164964702 0.65 ENSRNOT00000014595
activity-dependent neuroprotector homeobox
chr5_-_50221095 0.65 ENSRNOT00000012164
similar to hypothetical protein
chr18_+_15738809 0.65 ENSRNOT00000075444
microtubule-associated protein, RP/EB family, member 2
chr20_-_5441706 0.55 ENSRNOT00000000549
VPS52 GARP complex subunit
chr5_+_138470069 0.48 ENSRNOT00000076343
ENSRNOT00000064073
zinc finger, MYND-type containing 12

Network of associatons between targets according to the STRING database.

First level regulatory network of Glis2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.9 GO:0002572 pro-T cell differentiation(GO:0002572)
3.6 14.3 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
3.0 9.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
3.0 8.9 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
2.7 8.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
2.7 16.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
2.7 8.0 GO:2000464 positive regulation of astrocyte chemotaxis(GO:2000464)
2.6 15.8 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
2.6 7.9 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
2.6 15.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
2.2 6.6 GO:0021550 neuroblast differentiation(GO:0014016) spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) medulla oblongata development(GO:0021550) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166)
1.9 5.8 GO:0055073 cadmium ion homeostasis(GO:0055073)
1.7 6.8 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
1.6 6.5 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.4 6.9 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
1.3 9.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
1.3 6.4 GO:0002317 plasma cell differentiation(GO:0002317)
1.3 9.0 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
1.3 3.8 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
1.2 7.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.1 4.4 GO:0035494 SNARE complex disassembly(GO:0035494)
1.1 3.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
1.0 10.4 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
1.0 8.8 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.9 9.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.8 6.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.8 4.6 GO:0072513 bundle of His development(GO:0003166) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.7 3.7 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.7 8.0 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.7 15.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.7 3.4 GO:0021747 cochlear nucleus development(GO:0021747)
0.7 4.6 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.6 1.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.6 8.4 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6 4.7 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.6 1.8 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.6 3.5 GO:0002457 T cell antigen processing and presentation(GO:0002457) dsRNA transport(GO:0033227)
0.5 7.0 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.5 2.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.5 6.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.5 8.8 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.5 5.1 GO:0000012 single strand break repair(GO:0000012)
0.5 1.5 GO:0021997 neural plate axis specification(GO:0021997)
0.5 9.8 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.5 13.8 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.5 5.9 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.4 3.1 GO:0070459 prolactin secretion(GO:0070459)
0.4 3.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.4 1.6 GO:1904640 response to methionine(GO:1904640)
0.4 4.0 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.4 7.5 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.4 4.2 GO:0010603 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.4 15.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.4 1.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.4 11.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 9.0 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.4 1.4 GO:1900104 hyaluranon cable assembly(GO:0036118) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 10.0 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.3 5.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.3 6.0 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.3 12.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.3 6.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.3 4.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.3 7.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3 1.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.3 2.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 1.2 GO:0015074 DNA integration(GO:0015074)
0.2 1.4 GO:0015808 L-alanine transport(GO:0015808)
0.2 1.4 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.2 8.8 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 6.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.2 1.1 GO:0042628 mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
0.2 10.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 1.8 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.2 1.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 1.3 GO:1904668 regulation of ubiquitin protein ligase activity(GO:1904666) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.2 5.0 GO:0034340 response to type I interferon(GO:0034340)
0.2 6.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 2.1 GO:0036035 osteoclast development(GO:0036035)
0.2 11.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 9.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 1.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 6.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 2.9 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 1.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 4.3 GO:0006817 phosphate ion transport(GO:0006817)
0.1 2.3 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 2.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 3.6 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.1 3.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 2.1 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 4.2 GO:0000245 spliceosomal complex assembly(GO:0000245) regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 9.1 GO:0007127 meiosis I(GO:0007127)
0.1 0.7 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 1.0 GO:0022038 corpus callosum development(GO:0022038)
0.1 2.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 4.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.5 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 5.7 GO:0051321 meiotic cell cycle(GO:0051321)
0.1 1.1 GO:0016578 histone deubiquitination(GO:0016578)
0.1 6.0 GO:0007612 learning(GO:0007612)
0.0 3.0 GO:0060996 dendritic spine development(GO:0060996)
0.0 3.7 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 3.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 8.2 GO:0030534 adult behavior(GO:0030534)
0.0 1.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 2.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.4 GO:0031529 ruffle organization(GO:0031529)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 7.7 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.6 GO:0042476 odontogenesis(GO:0042476)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.3 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.2 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 1.0 GO:0030282 bone mineralization(GO:0030282)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 3.2 GO:0007265 Ras protein signal transduction(GO:0007265)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
1.9 5.8 GO:0070821 tertiary granule membrane(GO:0070821)
1.4 6.8 GO:0045098 type III intermediate filament(GO:0045098)
1.3 11.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
1.3 6.4 GO:0016939 kinesin II complex(GO:0016939)
1.0 14.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
1.0 14.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.8 2.5 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.7 4.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.7 2.1 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.7 19.6 GO:0042629 mast cell granule(GO:0042629)
0.7 8.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.7 2.7 GO:0097451 glial limiting end-foot(GO:0097451)
0.5 3.8 GO:0042382 paraspeckles(GO:0042382)
0.5 1.4 GO:0036117 hyaluranon cable(GO:0036117)
0.5 7.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 3.7 GO:0097443 sorting endosome(GO:0097443)
0.4 4.0 GO:0000805 X chromosome(GO:0000805)
0.4 1.5 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.4 15.8 GO:0060170 ciliary membrane(GO:0060170)
0.3 6.8 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.3 0.9 GO:0070939 Dsl1p complex(GO:0070939)
0.3 9.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.3 8.7 GO:0034451 centriolar satellite(GO:0034451)
0.3 10.6 GO:0044295 axonal growth cone(GO:0044295)
0.3 1.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.2 2.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 0.9 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 7.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 15.3 GO:0000786 nucleosome(GO:0000786)
0.2 1.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.5 GO:1990745 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.1 4.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 12.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 12.8 GO:0005901 caveola(GO:0005901)
0.1 8.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 8.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 37.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 6.9 GO:0030139 endocytic vesicle(GO:0030139)
0.1 14.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 7.9 GO:0005902 microvillus(GO:0005902)
0.1 4.4 GO:0032420 stereocilium(GO:0032420)
0.1 1.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 20.2 GO:0043209 myelin sheath(GO:0043209)
0.1 7.2 GO:0045095 keratin filament(GO:0045095)
0.1 6.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 6.0 GO:0005643 nuclear pore(GO:0005643)
0.1 8.7 GO:0005814 centriole(GO:0005814)
0.1 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 3.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 4.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.5 GO:0030904 retromer complex(GO:0030904)
0.1 30.4 GO:0030424 axon(GO:0030424)
0.1 5.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 4.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 2.1 GO:0005844 polysome(GO:0005844)
0.0 7.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 8.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.7 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 23.6 GO:0005730 nucleolus(GO:0005730)
0.0 2.5 GO:0000922 spindle pole(GO:0000922)
0.0 4.7 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 4.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 16.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
3.1 15.6 GO:0004974 leukotriene receptor activity(GO:0004974)
3.0 8.9 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
2.7 8.0 GO:0071791 chemokine (C-C motif) ligand 5 binding(GO:0071791)
2.6 15.8 GO:0004994 somatostatin receptor activity(GO:0004994)
2.4 7.3 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
2.2 6.5 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
1.6 7.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.5 4.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
1.4 4.3 GO:0052724 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
1.4 6.8 GO:1990254 keratin filament binding(GO:1990254)
1.3 9.1 GO:0050692 DBD domain binding(GO:0050692)
1.2 14.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.2 6.9 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
1.1 3.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
1.0 3.9 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
1.0 6.8 GO:0001849 complement component C1q binding(GO:0001849)
0.8 8.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.8 3.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.7 9.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.7 7.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.6 4.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.6 5.8 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.6 11.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.5 2.1 GO:0036004 GAF domain binding(GO:0036004)
0.5 25.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.5 12.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.5 4.6 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.5 1.5 GO:0005119 smoothened binding(GO:0005119)
0.5 15.8 GO:0042169 SH2 domain binding(GO:0042169)
0.5 3.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.5 1.4 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.4 6.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.4 3.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 11.7 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.3 9.0 GO:0003785 actin monomer binding(GO:0003785)
0.3 1.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 1.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 9.5 GO:0005158 insulin receptor binding(GO:0005158)
0.2 2.7 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 4.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.7 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.2 2.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 6.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 3.6 GO:0005537 mannose binding(GO:0005537)
0.2 10.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 7.5 GO:0042605 peptide antigen binding(GO:0042605)
0.2 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.2 12.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.2 2.7 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.2 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 6.5 GO:0005504 fatty acid binding(GO:0005504)
0.1 6.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 4.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 0.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 6.1 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 1.8 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 2.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 4.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 8.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 8.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 3.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 6.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 15.5 GO:0051015 actin filament binding(GO:0051015)
0.1 4.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 4.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 5.1 GO:0004527 exonuclease activity(GO:0004527)
0.1 1.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 2.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 3.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 55.5 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 7.8 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 3.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 10.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 5.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.5 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.7 GO:0019825 oxygen binding(GO:0019825)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 6.5 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.9 GO:0004601 peroxidase activity(GO:0004601)
0.0 7.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 1.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.0 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 14.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.6 25.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.5 10.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.4 25.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.4 7.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 24.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.4 13.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 15.6 PID ENDOTHELIN PATHWAY Endothelins
0.3 9.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.3 4.6 PID ALK2 PATHWAY ALK2 signaling events
0.3 9.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 5.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 3.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 11.8 PID CDC42 PATHWAY CDC42 signaling events
0.2 8.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 3.2 PID IL1 PATHWAY IL1-mediated signaling events
0.1 6.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 5.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 3.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 6.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 8.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.1 15.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
1.1 14.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.1 14.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.8 9.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.7 16.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.7 15.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.7 12.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6 15.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.5 8.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.5 9.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.5 10.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.5 8.9 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.4 7.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.3 3.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.3 13.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 6.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 6.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 4.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 6.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 4.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.2 6.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.2 7.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 4.2 REACTOME KINESINS Genes involved in Kinesins
0.1 6.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 9.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 14.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 3.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 27.5 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 2.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 3.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 3.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 4.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 3.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 3.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation