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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hic2

Z-value: 1.60

Motif logo

Transcription factors associated with Hic2

Gene Symbol Gene ID Gene Info
ENSRNOG00000051458 HIC ZBTB transcriptional repressor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hic2rn6_v1_chr11_-_88016825_880168250.062.5e-01Click!

Activity profile of Hic2 motif

Sorted Z-values of Hic2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_80517536 101.07 ENSRNOT00000004386
myocilin
chr5_+_1417478 66.21 ENSRNOT00000008153
ENSRNOT00000085564
junctophilin 1
chr8_+_49441106 65.85 ENSRNOT00000030152
sodium voltage-gated channel beta subunit 4
chr17_+_47397558 62.77 ENSRNOT00000085923
ependymin related 1
chr4_+_7076759 62.35 ENSRNOT00000066598
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr3_-_159775643 56.73 ENSRNOT00000010939
junctophilin 2
chr7_+_94375020 51.61 ENSRNOT00000011904
nephroblastoma overexpressed
chr10_+_92289107 48.34 ENSRNOT00000050070
microtubule-associated protein tau
chr1_+_80321585 48.23 ENSRNOT00000022895
creatine kinase, M-type
chr10_+_92288910 47.69 ENSRNOT00000006947
ENSRNOT00000045127
microtubule-associated protein tau
chr1_+_198655742 47.23 ENSRNOT00000023944
myosin light chain, phosphorylatable, fast skeletal muscle
chr13_+_51034256 45.04 ENSRNOT00000004528
ENSRNOT00000046854
ENSRNOT00000087320
myosin binding protein H
chr8_-_116361343 45.02 ENSRNOT00000066296
semaphorin 3B
chr1_+_215666628 42.69 ENSRNOT00000040598
ENSRNOT00000066135
ENSRNOT00000051425
ENSRNOT00000080339
ENSRNOT00000066896
ENSRNOT00000063918
troponin T3, fast skeletal type
chr10_+_53778662 42.09 ENSRNOT00000045718
myosin heavy chain 2
chr10_+_57278307 42.04 ENSRNOT00000005612
enolase 3
chr3_+_11114551 40.15 ENSRNOT00000013507
phospholipid phosphatase 7
chr6_-_137353249 39.49 ENSRNOT00000039631
AHNAK nucleoprotein 2
chr14_-_86297623 38.74 ENSRNOT00000067162
ENSRNOT00000081607
ENSRNOT00000085265
calcium/calmodulin-dependent protein kinase II beta
chr3_+_11653529 38.67 ENSRNOT00000091048
adenylate kinase 1
chr6_-_133716847 35.47 ENSRNOT00000072399
retrotransposon-like 1
chr18_-_55916220 35.37 ENSRNOT00000025934
synaptopodin
chr5_-_135677432 35.16 ENSRNOT00000024393
4-hydroxyphenylpyruvate dioxygenase-like
chr17_-_19580929 34.80 ENSRNOT00000023613
guanosine monophosphate reductase
chr15_+_33632416 34.77 ENSRNOT00000068212

chr1_-_215033460 33.65 ENSRNOT00000044565
dual specificity phosphatase 8
chr2_-_21437193 33.49 ENSRNOT00000084002
creatine kinase, mitochondrial 2
chr3_+_80075991 32.41 ENSRNOT00000080266
protein kinase C and casein kinase substrate in neurons 3
chr7_+_117519075 29.94 ENSRNOT00000029768
scleraxis bHLH transcription factor
chr4_+_61814974 28.99 ENSRNOT00000074951
aldo-keto reductase family 1 member B10
chr1_+_137799185 27.30 ENSRNOT00000083590
ENSRNOT00000092778
ATP/GTP binding protein-like 1
chr3_+_148386189 26.86 ENSRNOT00000011255
myosin light chain kinase 2
chr17_+_9109731 26.19 ENSRNOT00000016009
C-X-C motif chemokine ligand 14
chr1_-_100671074 25.37 ENSRNOT00000027132
myosin heavy chain 14
chr8_-_49025917 25.35 ENSRNOT00000078816
pleckstrin homology-like domain, family B, member 1
chr4_-_30556814 25.17 ENSRNOT00000012760
pyruvate dehydrogenase kinase 4
chr1_-_143392532 25.03 ENSRNOT00000026089
fibronectin type III and SPRY domain containing 2
chr7_-_98709344 24.93 ENSRNOT00000064122
transmembrane protein 65
chr5_-_79874671 24.76 ENSRNOT00000084563
tenascin C
chr5_+_159428515 24.65 ENSRNOT00000010183
peptidyl arginine deiminase 2
chr13_-_52197205 24.42 ENSRNOT00000009712
shisa family member 4
chr10_-_94557764 23.79 ENSRNOT00000016841
sodium voltage-gated channel alpha subunit 4
chr8_-_55177818 23.63 ENSRNOT00000013960
heat shock protein family B (small) member 2
chr5_-_58078545 23.12 ENSRNOT00000075777
ciliary neurotrophic factor receptor
chr10_-_10629735 22.99 ENSRNOT00000061253
SEC14-like lipid binding 5
chr9_-_82699551 22.78 ENSRNOT00000020673
obscurin-like 1
chr6_+_76349362 22.55 ENSRNOT00000043224
aldolase 1 A retrogene 2
chr1_+_53360157 22.36 ENSRNOT00000017809
ribosomal protein S6 kinase A2
chr8_+_58870516 22.35 ENSRNOT00000033900
gliomedin
chr19_-_12942943 22.02 ENSRNOT00000064105
ENSRNOT00000090886
LARGE xylosyl- and glucuronyltransferase 1
chr9_+_94286550 22.00 ENSRNOT00000026504
cholinergic receptor nicotinic delta subunit
chr7_+_143749221 21.94 ENSRNOT00000014807
insulin-like growth factor binding protein 6
chr14_-_17225389 21.23 ENSRNOT00000052035
ADP-ribosyltransferase 3
chr14_-_13058172 20.92 ENSRNOT00000002746
ENSRNOT00000071706
PR/SET domain 8
chr1_-_198232344 20.74 ENSRNOT00000080988
aldolase, fructose-bisphosphate A
chr11_+_66713888 20.69 ENSRNOT00000003340
F-box protein 40
chr13_+_52889737 20.36 ENSRNOT00000074366
calcium voltage-gated channel subunit alpha1 S
chr2_+_119197239 20.33 ENSRNOT00000048030
ubiquitin specific peptidase 13
chr15_+_52220578 20.30 ENSRNOT00000015104
leucine-rich repeat LGI family, member 3
chr1_-_241875864 19.89 ENSRNOT00000091282
family with sequence similarity 189, member A2
chr19_-_10596851 19.78 ENSRNOT00000021716
coenzyme Q9
chr4_-_117490721 19.45 ENSRNOT00000021103
N-acetyltransferase 8 (GCN5-related) family member 3
chrX_-_157312028 19.44 ENSRNOT00000077979
ATPase plasma membrane Ca2+ transporting 3
chr16_-_81945127 19.43 ENSRNOT00000023352
MCF.2 cell line derived transforming sequence-like
chr16_-_10941414 19.43 ENSRNOT00000086627
ENSRNOT00000085414
ENSRNOT00000081631
ENSRNOT00000087521
ENSRNOT00000083623
LIM domain binding 3
chr2_-_227411964 19.08 ENSRNOT00000019931
synaptopodin 2
chr2_-_172361779 18.44 ENSRNOT00000085876
schwannomin interacting protein 1
chr2_-_62634785 18.44 ENSRNOT00000017937
PDZ domain containing 2
chr10_-_85974644 18.41 ENSRNOT00000006098
ENSRNOT00000082974
calcium voltage-gated channel auxiliary subunit beta 1
chr20_+_31096214 18.04 ENSRNOT00000000676
leucine rich repeat containing 20
chr3_+_97723901 17.63 ENSRNOT00000080416
metallophosphoesterase domain containing 2
chr8_+_4440876 17.38 ENSRNOT00000049325
ENSRNOT00000076529
ENSRNOT00000076748
platelet derived growth factor D
chr4_+_71675383 17.37 ENSRNOT00000051265
chloride voltage-gated channel 1
chr1_+_47605262 17.23 ENSRNOT00000089458
fibronectin type III domain containing 1
chr12_-_44381289 16.71 ENSRNOT00000001493
nitric oxide synthase 1
chr4_-_170860225 16.37 ENSRNOT00000007577
matrix Gla protein
chr20_-_5754773 16.31 ENSRNOT00000035977
inositol hexakisphosphate kinase 3
chr7_+_14037620 16.28 ENSRNOT00000009606
synapse defective Rho GTPase homolog 1
chr8_-_122987191 16.24 ENSRNOT00000033976
glycerol-3-phosphate dehydrogenase 1-like
chr7_-_117257402 16.01 ENSRNOT00000081021
plectin
chr1_+_220446425 15.96 ENSRNOT00000027339
endosialin-like
chr5_+_36555109 15.75 ENSRNOT00000061128
F-box and leucine-rich repeat protein 4
chr4_-_7228675 15.57 ENSRNOT00000064386
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_+_80982358 15.54 ENSRNOT00000078462

chr1_-_259484569 15.50 ENSRNOT00000021289
ENSRNOT00000021114
ENSRNOT00000021229
ENSRNOT00000021347
ENSRNOT00000021226
sorbin and SH3 domain containing 1
chr14_+_60123169 15.30 ENSRNOT00000006610
SEL1L family member 3
chrX_+_62363757 15.11 ENSRNOT00000091240
aristaless related homeobox
chr6_+_41917132 14.87 ENSRNOT00000071387
neurotensin receptor 2
chr10_+_104523996 14.82 ENSRNOT00000065339
ENSRNOT00000086747
integrin subunit beta 4
chr1_+_72425707 14.71 ENSRNOT00000058956
SH3 domain binding kinase family, member 2
chr5_+_61657507 14.66 ENSRNOT00000013228
tropomodulin 1
chr7_+_143707237 14.63 ENSRNOT00000074212
tensin 2
chr1_-_82266727 14.63 ENSRNOT00000027910
lipase E, hormone sensitive type
chr8_-_117382715 14.61 ENSRNOT00000027466
prolyl 4-hydroxylase, transmembrane
chr13_-_52136127 14.44 ENSRNOT00000009398
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr5_-_124642569 14.33 ENSRNOT00000010680
protein kinase AMP-activated catalytic subunit alpha 2
chr1_+_47605415 14.22 ENSRNOT00000034842
fibronectin type III domain containing 1
chr3_+_111160205 14.12 ENSRNOT00000019392
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
chr3_+_79860179 14.10 ENSRNOT00000081160
ENSRNOT00000068444
receptor-associated protein of the synapse
chr6_-_75763185 14.04 ENSRNOT00000072589
cofilin 2
chr6_+_133552821 13.96 ENSRNOT00000006339
delta like non-canonical Notch ligand 1
chr5_-_102786331 13.91 ENSRNOT00000086635
basonuclin 2
chr17_+_13519130 13.82 ENSRNOT00000076794
semaphorin 4D
chr6_+_133576568 13.79 ENSRNOT00000085933
delta like non-canonical Notch ligand 1
chr9_+_82741920 13.77 ENSRNOT00000027337
solute carrier family 4 member 3
chrX_+_62363953 13.72 ENSRNOT00000083362
aristaless related homeobox
chr11_-_81344488 13.52 ENSRNOT00000002492
adiponectin, C1Q and collagen domain containing
chr6_-_105097054 13.50 ENSRNOT00000048606
solute carrier family 8 member A3
chr9_-_85617954 13.45 ENSRNOT00000077331
serpin family E member 2
chr4_-_159079003 13.33 ENSRNOT00000026691
potassium voltage-gated channel subfamily A member 5
chr9_+_97355924 13.27 ENSRNOT00000026558
atypical chemokine receptor 3
chr14_-_78902063 13.26 ENSRNOT00000088469
protein phosphatase 2, regulatory subunit B, gamma
chr16_-_64778486 13.17 ENSRNOT00000031701
ring finger protein 122
chr2_-_211207465 13.06 ENSRNOT00000027263
cadherin, EGF LAG seven-pass G-type receptor 2
chr1_+_220353356 13.00 ENSRNOT00000080189
CD248 molecule
chr19_-_9801942 13.00 ENSRNOT00000051414
ENSRNOT00000017494
NDRG family member 4
chr10_+_86669233 12.93 ENSRNOT00000012340
thyroid hormone receptor alpha
chr14_-_84170301 12.91 ENSRNOT00000080413
solute carrier family 35, member E4
chr7_+_11356118 12.83 ENSRNOT00000041325
ATCAY, caytaxin
chr20_+_5008508 12.72 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chrX_+_68752597 12.69 ENSRNOT00000077039
StAR-related lipid transfer domain containing 8
chr17_+_9653561 12.65 ENSRNOT00000018899
PDZ and LIM domain 7
chr3_-_72602548 12.62 ENSRNOT00000031745
leucine rich repeat containing 55
chr9_-_114709546 12.55 ENSRNOT00000026177
RAB12, member RAS oncogene family
chr15_-_86105273 12.52 ENSRNOT00000012600
ENSRNOT00000064942
TBC1 domain family, member 4
chr5_-_25584278 12.48 ENSRNOT00000090579
ENSRNOT00000090376
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr9_-_85626094 12.44 ENSRNOT00000020919
serpin family E member 2
chr10_+_110631494 12.43 ENSRNOT00000054915
fructosamine 3 kinase
chr12_-_44520341 12.42 ENSRNOT00000066810
nitric oxide synthase 1
chr3_-_8979889 12.40 ENSRNOT00000065128
carnitine O-acetyltransferase
chr8_-_49045154 12.37 ENSRNOT00000088034
pleckstrin homology-like domain, family B, member 1
chr5_-_64850427 12.35 ENSRNOT00000008883
transmembrane protein 246
chr1_-_222177421 12.22 ENSRNOT00000078393
estrogen related receptor, alpha
chr7_-_116255167 12.20 ENSRNOT00000038109
ENSRNOT00000041774
cytochrome P450, family 11, subfamily b, polypeptide 2
chr18_+_30398113 12.19 ENSRNOT00000027206
protocadherin beta 5
chr7_+_141370491 12.07 ENSRNOT00000087662
glycerol-3-phosphate dehydrogenase 1
chr13_-_82006005 12.06 ENSRNOT00000039581
methyltransferase like 11B
chr5_+_14890408 12.06 ENSRNOT00000033116
SRY box 17
chr10_+_85608544 11.99 ENSRNOT00000092122
MLLT6, PHD finger domain containing
chr5_-_24320786 11.98 ENSRNOT00000061569
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr10_-_84698886 11.96 ENSRNOT00000067542
nuclear factor, erythroid 2-like 1
chr1_-_70235091 11.96 ENSRNOT00000075745
antisense paternally expressed gene 3
chr16_+_2537248 11.95 ENSRNOT00000017995
ankyrin repeat and SOCS box-containing 14
chr15_+_39945095 11.76 ENSRNOT00000016826
shisa family member 2
chr1_+_245237736 11.75 ENSRNOT00000035814
very low density lipoprotein receptor
chr3_+_172385672 11.73 ENSRNOT00000090989
GNAS complex locus
chr17_+_70684340 11.65 ENSRNOT00000051067
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr4_-_61720956 11.64 ENSRNOT00000012879
aldo-keto reductase family 1 member B
chr14_+_77712240 11.57 ENSRNOT00000009101
msh homeobox 1
chr1_-_101085884 11.55 ENSRNOT00000085352
reticulocalbin 3
chr8_-_89130991 11.46 ENSRNOT00000017411
5-hydroxytryptamine receptor 1B
chr7_-_117259791 11.34 ENSRNOT00000086550
plectin
chr8_+_79606789 11.31 ENSRNOT00000087114
pygopus family PHD finger 1
chr19_-_10101451 11.24 ENSRNOT00000017629
matrix metallopeptidase 15
chr7_-_121232741 10.99 ENSRNOT00000023196
platelet derived growth factor subunit B
chr19_+_20147037 10.96 ENSRNOT00000020028
zinc finger protein 423
chr8_-_116993193 10.91 ENSRNOT00000026327
dystroglycan 1
chr2_-_235062487 10.87 ENSRNOT00000093258
uncharacterized LOC103691699
chr15_-_28314459 10.84 ENSRNOT00000042055
ENSRNOT00000040540
NDRG family member 2
chr17_+_70684539 10.83 ENSRNOT00000025700
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_-_64321241 10.79 ENSRNOT00000081837
calcium voltage-gated channel auxiliary subunit gamma 6
chr5_-_135025084 10.76 ENSRNOT00000018766
tetraspanin 1
chr2_+_187740531 10.71 ENSRNOT00000092653
progestin and adipoQ receptor family member 6
chr10_-_62483342 10.70 ENSRNOT00000079956
hypermethylated in cancer 1 protein-like
chr19_+_24701049 10.52 ENSRNOT00000035890
NADH:ubiquinone oxidoreductase subunit B7
chr1_+_274391932 10.52 ENSRNOT00000054685
RNA binding motif protein 20
chr2_+_174542667 10.48 ENSRNOT00000076793
follistatin-like 5
chr9_-_82382272 10.26 ENSRNOT00000025627
ATP-binding cassette, subfamily B (MDR/TAP), member 6
chr8_-_109621408 10.24 ENSRNOT00000087398
protein phosphatase 2, regulatory subunit B'', alpha
chr5_-_166282831 10.23 ENSRNOT00000021348
retinol binding protein 7
chr1_+_220362064 10.22 ENSRNOT00000074361
endosialin
chr6_+_60566196 10.21 ENSRNOT00000006709
ENSRNOT00000075193
dedicator of cytokinesis 4
chr3_-_177179127 10.20 ENSRNOT00000021790
SRY box 18
chr6_+_48866601 10.16 ENSRNOT00000077321
ENSRNOT00000079891
peroxidasin
chr10_-_65080535 10.14 ENSRNOT00000088919
myosin XVIIIa
chr17_+_70684134 10.13 ENSRNOT00000025731
ENSRNOT00000068354
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_-_267203986 10.04 ENSRNOT00000027574
SH3 and PX domains 2A
chr1_-_242765807 9.97 ENSRNOT00000020763
phosphoglucomutase 5
chr1_+_144239020 9.93 ENSRNOT00000032106
ADAMTS-like 3
chrX_-_32095867 9.87 ENSRNOT00000049947
ENSRNOT00000080730
angiotensin I converting enzyme 2
chr1_+_102414625 9.85 ENSRNOT00000089488
potassium voltage-gated channel subfamily C member 1
chr7_-_117265493 9.82 ENSRNOT00000083429
plectin
chr1_-_101086198 9.65 ENSRNOT00000027917
reticulocalbin 3
chr3_+_152552822 9.65 ENSRNOT00000089719
erythrocyte membrane protein band 4.1-like 1
chrX_+_105500173 9.64 ENSRNOT00000040476
armadillo repeat containing, X-linked 4
chr18_+_64114933 9.61 ENSRNOT00000022364
melanocortin 5 receptor
chr12_-_19167015 9.57 ENSRNOT00000001797
gap junction protein, gamma 3
chr1_-_89488223 9.55 ENSRNOT00000028624
FXYD domain-containing ion transport regulator 1
chr5_-_145377221 9.51 ENSRNOT00000019246
gap junction protein, alpha 4
chrX_-_156428593 9.49 ENSRNOT00000089778
tafazzin
chr2_+_227657983 9.49 ENSRNOT00000021116
protease, serine 12
chr14_-_85484275 9.46 ENSRNOT00000083770
kringle containing transmembrane protein 1
chr2_-_210116038 9.38 ENSRNOT00000074950
similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr1_+_226435979 9.33 ENSRNOT00000048704
ENSRNOT00000036232
ENSRNOT00000035576
ENSRNOT00000036180
ENSRNOT00000036168
ENSRNOT00000047964
ENSRNOT00000036283
ENSRNOT00000007429
synaptotagmin 7
chr8_+_6811543 9.31 ENSRNOT00000008905
ENSRNOT00000042553
transient receptor potential cation channel, subfamily C, member 6
chr1_+_199351628 9.30 ENSRNOT00000078578
branched chain ketoacid dehydrogenase kinase
chr10_+_16542882 9.25 ENSRNOT00000028146
stanniocalcin 2
chr2_-_208420163 9.25 ENSRNOT00000021920
ATP synthase subunit b, mitochondrial-like
chr13_-_100928811 9.20 ENSRNOT00000045326
calpain 2
chr7_-_122926336 9.15 ENSRNOT00000000205
chondroadherin-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Hic2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
25.4 101.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
17.2 51.6 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392) negative regulation of sensory perception of pain(GO:1904057)
15.6 62.4 GO:0003219 cardiac right ventricle formation(GO:0003219)
12.9 38.7 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
12.9 38.7 GO:0046103 inosine biosynthetic process(GO:0046103)
12.1 109.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
11.8 35.3 GO:0016107 sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
9.0 26.9 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
8.8 35.4 GO:0098886 modification of dendritic spine(GO:0098886)
8.5 33.9 GO:0007525 somatic muscle development(GO:0007525)
8.2 82.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
8.1 56.7 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
7.5 30.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
7.3 36.6 GO:0035993 deltoid tuberosity development(GO:0035993)
7.3 7.3 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
7.2 21.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
7.0 42.1 GO:0031034 myosin filament assembly(GO:0031034)
6.5 19.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
6.4 38.7 GO:0021759 globus pallidus development(GO:0021759)
6.4 25.7 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
6.3 25.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
6.2 24.6 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
5.9 35.2 GO:0006572 tyrosine catabolic process(GO:0006572)
5.8 17.4 GO:2000437 regulation of monocyte extravasation(GO:2000437)
5.8 11.6 GO:0090427 activation of meiosis(GO:0090427)
5.6 22.3 GO:0048865 stem cell fate commitment(GO:0048865) endocardium formation(GO:0060214)
5.4 48.8 GO:0001778 plasma membrane repair(GO:0001778)
5.4 32.2 GO:0002035 brain renin-angiotensin system(GO:0002035)
5.2 25.9 GO:0045297 mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
5.1 20.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
5.1 20.3 GO:1904378 protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) protein K6-linked deubiquitination(GO:0044313) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
5.0 15.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
5.0 14.9 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
4.9 24.5 GO:0072244 metanephric glomerular epithelium development(GO:0072244)
4.9 14.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
4.8 38.2 GO:1990034 calcium ion export from cell(GO:1990034)
4.5 27.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
4.5 22.3 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
4.4 26.2 GO:0035747 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
4.3 12.8 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
4.2 8.3 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
4.0 12.1 GO:0006116 NADH oxidation(GO:0006116)
4.0 12.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
4.0 12.0 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
3.9 11.6 GO:0006059 hexitol metabolic process(GO:0006059)
3.7 48.6 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
3.7 3.7 GO:0014904 myotube cell development(GO:0014904)
3.7 65.9 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
3.4 64.7 GO:0031581 hemidesmosome assembly(GO:0031581)
3.4 10.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
3.4 10.1 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
3.3 13.3 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
3.3 56.1 GO:0006000 fructose metabolic process(GO:0006000)
3.1 9.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
3.1 15.5 GO:1904008 response to monosodium glutamate(GO:1904008)
3.1 12.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
3.1 9.2 GO:0032499 detection of peptidoglycan(GO:0032499)
3.0 9.1 GO:0006533 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
3.0 9.0 GO:0061350 cardiac right atrium morphogenesis(GO:0003213) Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) melanocyte proliferation(GO:0097325)
3.0 23.8 GO:0015871 choline transport(GO:0015871)
2.9 11.8 GO:0034436 glycoprotein transport(GO:0034436)
2.8 11.4 GO:0030043 actin filament fragmentation(GO:0030043)
2.8 8.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
2.8 22.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
2.8 41.8 GO:1903779 regulation of cardiac conduction(GO:1903779)
2.8 8.3 GO:1903195 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) TRAIL receptor biosynthetic process(GO:0045557) regulation of TRAIL receptor biosynthetic process(GO:0045560) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) regulation of cellular amino acid biosynthetic process(GO:2000282) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
2.7 10.8 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.7 16.1 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
2.7 5.3 GO:0097187 dentinogenesis(GO:0097187)
2.6 13.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
2.6 7.8 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
2.5 7.6 GO:0006083 acetate metabolic process(GO:0006083)
2.5 7.5 GO:1990792 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
2.5 7.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
2.4 9.6 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
2.4 9.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
2.4 4.7 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
2.4 7.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
2.4 2.4 GO:0060577 pulmonary vein morphogenesis(GO:0060577)
2.3 11.5 GO:0071502 cellular response to temperature stimulus(GO:0071502)
2.3 4.6 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
2.2 8.9 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
2.2 6.6 GO:0071640 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) macrophage inflammatory protein-1 alpha production(GO:0071608) regulation of macrophage inflammatory protein 1 alpha production(GO:0071640) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
2.2 6.6 GO:0043060 meiotic metaphase I plate congression(GO:0043060)
2.2 8.7 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121)
2.1 2.1 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
2.1 20.9 GO:0021540 corpus callosum morphogenesis(GO:0021540)
2.1 6.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
2.1 8.3 GO:0048550 negative regulation of pinocytosis(GO:0048550)
2.1 6.2 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
2.1 4.1 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
2.1 8.2 GO:0035106 operant conditioning(GO:0035106)
2.0 12.2 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
2.0 90.1 GO:0003009 skeletal muscle contraction(GO:0003009)
1.9 5.8 GO:0006552 leucine catabolic process(GO:0006552)
1.9 40.2 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
1.8 5.4 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
1.8 14.1 GO:0006751 glutathione catabolic process(GO:0006751)
1.8 8.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.8 5.3 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106) protein localization to site of double-strand break(GO:1990166)
1.8 5.3 GO:1990523 bone regeneration(GO:1990523)
1.7 7.0 GO:0021586 pons maturation(GO:0021586)
1.7 17.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.7 5.1 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
1.7 10.0 GO:0072675 osteoclast fusion(GO:0072675)
1.7 11.6 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
1.7 8.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.7 8.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.7 31.4 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
1.6 4.9 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.6 4.8 GO:0031989 bombesin receptor signaling pathway(GO:0031989)
1.6 6.5 GO:0032264 IMP salvage(GO:0032264)
1.6 6.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
1.6 25.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
1.6 4.7 GO:0089718 amino acid import across plasma membrane(GO:0089718)
1.6 3.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.6 25.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.6 4.7 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
1.6 12.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
1.5 1.5 GO:0031944 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947)
1.5 7.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.5 4.5 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
1.5 32.4 GO:0097320 membrane tubulation(GO:0097320)
1.5 5.8 GO:0014028 notochord formation(GO:0014028)
1.4 13.0 GO:2001135 regulation of endocytic recycling(GO:2001135)
1.4 10.0 GO:0019388 galactose catabolic process(GO:0019388)
1.4 7.1 GO:0044691 tooth eruption(GO:0044691)
1.4 2.8 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
1.4 8.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
1.4 4.1 GO:0009644 response to high light intensity(GO:0009644)
1.4 5.5 GO:0042268 regulation of cytolysis(GO:0042268)
1.3 8.1 GO:0023041 neuronal signal transduction(GO:0023041)
1.3 5.4 GO:1902023 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
1.3 6.7 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
1.2 6.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
1.2 3.6 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) basophil activation(GO:0045575)
1.2 29.0 GO:0014850 response to muscle activity(GO:0014850)
1.2 18.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.2 34.8 GO:0006144 purine nucleobase metabolic process(GO:0006144)
1.2 14.3 GO:0016081 synaptic vesicle docking(GO:0016081)
1.2 3.5 GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
1.2 14.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
1.1 3.4 GO:0090669 telomerase RNA stabilization(GO:0090669)
1.1 36.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
1.1 4.5 GO:0052314 phytoalexin metabolic process(GO:0052314)
1.1 7.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.1 6.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.1 4.3 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
1.1 3.2 GO:0036115 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) fatty-acyl-CoA catabolic process(GO:0036115)
1.1 4.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.1 4.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
1.0 15.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
1.0 19.9 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.0 3.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
1.0 6.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.0 42.4 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
1.0 7.0 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
1.0 9.8 GO:2001023 regulation of response to drug(GO:2001023)
1.0 5.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.0 12.4 GO:0071493 cellular response to UV-B(GO:0071493)
0.9 2.8 GO:1901558 response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.9 2.8 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.9 14.0 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.9 2.8 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.9 33.9 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.9 0.9 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.9 3.6 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.9 18.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.9 2.7 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
0.9 2.7 GO:0061643 chemoattraction of axon(GO:0061642) chemorepulsion of axon(GO:0061643)
0.9 3.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) cloacal septation(GO:0060197)
0.9 13.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.9 8.6 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.8 8.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.8 9.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.8 3.4 GO:0018158 protein oxidation(GO:0018158)
0.8 9.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.8 9.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.8 11.8 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.8 7.5 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705)
0.8 5.0 GO:1903012 positive regulation of bone development(GO:1903012)
0.8 6.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.8 3.3 GO:1901509 proteoglycan catabolic process(GO:0030167) regulation of endothelial tube morphogenesis(GO:1901509)
0.8 17.3 GO:0001553 luteinization(GO:0001553)
0.8 3.3 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.8 6.5 GO:0061042 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) vascular wound healing(GO:0061042)
0.8 24.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.8 1.6 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.8 4.7 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.8 1.5 GO:0060157 urinary bladder development(GO:0060157)
0.8 4.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.7 5.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.7 3.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.7 0.7 GO:0061317 canonical Wnt signaling pathway involved in heart development(GO:0061316) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.7 6.6 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.7 6.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.7 2.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.7 5.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.7 2.8 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.7 2.8 GO:0006004 fucose metabolic process(GO:0006004)
0.7 20.7 GO:0018149 peptide cross-linking(GO:0018149)
0.7 4.8 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.7 10.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.7 9.2 GO:0016540 protein autoprocessing(GO:0016540)
0.7 4.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.7 3.3 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.6 2.6 GO:1902534 single-organism membrane invagination(GO:1902534)
0.6 10.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.6 3.2 GO:0060594 mammary gland specification(GO:0060594)
0.6 3.7 GO:0035878 nail development(GO:0035878)
0.6 3.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.6 2.4 GO:0043988 histone H3-S10 phosphorylation(GO:0043987) histone H3-S28 phosphorylation(GO:0043988)
0.6 18.2 GO:0045214 sarcomere organization(GO:0045214)
0.6 9.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.6 13.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.6 1.8 GO:0035927 RNA import into mitochondrion(GO:0035927) rRNA import into mitochondrion(GO:0035928)
0.6 9.0 GO:0043586 tongue development(GO:0043586)
0.5 2.7 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.5 2.7 GO:0061525 hindgut development(GO:0061525)
0.5 4.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.5 5.4 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.5 5.9 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.5 11.7 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.5 11.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.5 7.9 GO:0006020 inositol metabolic process(GO:0006020)
0.5 10.9 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.5 13.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.5 4.9 GO:0006657 CDP-choline pathway(GO:0006657)
0.5 1.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.5 7.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.5 4.9 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.5 8.2 GO:0015732 prostaglandin transport(GO:0015732)
0.5 2.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.5 0.9 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.5 1.9 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.5 7.9 GO:0032274 gonadotropin secretion(GO:0032274)
0.5 4.1 GO:0007000 nucleolus organization(GO:0007000)
0.5 4.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.5 8.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.4 12.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.4 2.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4 4.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.4 21.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.4 59.5 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.4 2.6 GO:0035754 B cell chemotaxis(GO:0035754)
0.4 5.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.4 6.7 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.4 8.2 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.4 1.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.4 9.7 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.4 0.8 GO:0071288 cellular response to mercury ion(GO:0071288)
0.4 4.8 GO:0007035 vacuolar acidification(GO:0007035)
0.4 2.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.4 4.3 GO:0006105 succinate metabolic process(GO:0006105)
0.4 2.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.4 1.9 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.4 1.4 GO:1990646 cellular response to prolactin(GO:1990646)
0.4 1.8 GO:0002076 osteoblast development(GO:0002076)
0.4 4.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.3 2.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 1.7 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.3 7.1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.3 16.4 GO:0030500 regulation of bone mineralization(GO:0030500)
0.3 9.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.3 1.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 32.9 GO:0030278 regulation of ossification(GO:0030278)
0.3 9.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 9.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.3 1.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 3.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.3 3.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.3 2.6 GO:0046479 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313) glycosphingolipid catabolic process(GO:0046479)
0.3 1.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 1.7 GO:0014060 regulation of epinephrine secretion(GO:0014060) positive regulation of transmission of nerve impulse(GO:0051971)
0.3 6.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.3 3.8 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.3 5.3 GO:0097186 amelogenesis(GO:0097186)
0.3 5.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.3 5.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 13.6 GO:0046031 ADP metabolic process(GO:0046031)
0.3 3.6 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.3 3.9 GO:0051205 protein insertion into membrane(GO:0051205)
0.3 2.3 GO:0042048 olfactory behavior(GO:0042048)
0.2 0.7 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.2 3.0 GO:0015825 L-serine transport(GO:0015825)
0.2 2.2 GO:0060736 prostate gland growth(GO:0060736)
0.2 3.6 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.2 16.7 GO:0000045 autophagosome assembly(GO:0000045)
0.2 2.4 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 7.7 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.2 2.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 1.7 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.2 4.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.2 3.5 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.2 2.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.2 1.4 GO:0015866 ADP transport(GO:0015866)
0.2 1.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 6.3 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.2 6.9 GO:0006040 amino sugar metabolic process(GO:0006040)
0.2 4.2 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 1.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 1.1 GO:0015705 iodide transport(GO:0015705)
0.2 13.1 GO:0009062 fatty acid catabolic process(GO:0009062)
0.2 22.5 GO:0007517 muscle organ development(GO:0007517)
0.2 5.3 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.2 0.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 3.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.2 0.5 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.2 5.0 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.2 1.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 1.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 2.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 5.0 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.2 0.3 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 3.0 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.1 1.4 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 0.8 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.4 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 7.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 1.8 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 12.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 2.3 GO:0097576 autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576)
0.1 11.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 4.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 1.1 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.1 3.8 GO:0009060 aerobic respiration(GO:0009060)
0.1 1.9 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 2.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.0 GO:0032060 bleb assembly(GO:0032060)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.4 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.1 2.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 3.3 GO:0032543 mitochondrial translation(GO:0032543)
0.1 2.7 GO:0042461 photoreceptor cell development(GO:0042461)
0.1 2.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 3.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.8 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 1.8 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.1 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 2.8 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.1 1.0 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.1 9.7 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.1 2.1 GO:0010883 regulation of lipid storage(GO:0010883)
0.1 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 3.6 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.1 1.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 8.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 4.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.6 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.1 0.2 GO:0072429 double-strand break repair via break-induced replication(GO:0000727) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 4.5 GO:0050821 protein stabilization(GO:0050821)
0.0 56.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.5 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 3.2 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
33.7 101.1 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
24.0 96.0 GO:0045298 tubulin complex(GO:0045298)
22.1 66.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
11.8 35.4 GO:0097444 spine apparatus(GO:0097444)
11.6 34.8 GO:1902560 GMP reductase complex(GO:1902560)
8.1 56.7 GO:0030314 junctional membrane complex(GO:0030314)
7.7 23.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
7.0 42.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
6.3 25.4 GO:0097513 myosin II filament(GO:0097513)
6.0 6.0 GO:0070069 cytochrome complex(GO:0070069)
5.9 71.1 GO:0005859 muscle myosin complex(GO:0005859)
5.7 28.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
5.3 42.1 GO:0005826 actomyosin contractile ring(GO:0005826)
5.2 15.5 GO:0005899 insulin receptor complex(GO:0005899)
4.9 58.4 GO:0071564 npBAF complex(GO:0071564)
4.5 89.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
4.4 13.3 GO:0046691 intracellular canaliculus(GO:0046691)
4.1 8.3 GO:0044393 microspike(GO:0044393)
3.6 42.7 GO:0005861 troponin complex(GO:0005861)
3.3 68.4 GO:0030056 hemidesmosome(GO:0030056)
3.1 21.9 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
3.1 9.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
2.6 71.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
2.4 37.7 GO:0045180 basal cortex(GO:0045180)
2.3 11.7 GO:1990130 Iml1 complex(GO:1990130)
2.3 11.6 GO:0097454 Schwann cell microvillus(GO:0097454)
2.3 7.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
2.3 6.9 GO:1990836 lysosomal matrix(GO:1990836)
2.3 22.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
2.2 6.6 GO:0005713 chiasma(GO:0005712) recombination nodule(GO:0005713)
2.2 25.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
2.0 69.3 GO:0016528 sarcoplasm(GO:0016528)
2.0 61.6 GO:0005921 gap junction(GO:0005921)
2.0 6.0 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
1.9 9.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.8 60.4 GO:0043034 costamere(GO:0043034)
1.7 31.9 GO:0001520 outer dense fiber(GO:0001520)
1.6 4.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.3 13.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.3 6.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
1.3 20.7 GO:0031430 M band(GO:0031430)
1.3 14.1 GO:0099634 postsynaptic specialization membrane(GO:0099634)
1.3 5.1 GO:0097451 glial limiting end-foot(GO:0097451)
1.2 21.8 GO:0005614 interstitial matrix(GO:0005614)
1.2 30.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.1 9.1 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
1.1 3.4 GO:0070557 PCNA-p21 complex(GO:0070557)
1.1 9.0 GO:0033268 node of Ranvier(GO:0033268)
1.1 16.7 GO:0032591 dendritic spine membrane(GO:0032591)
1.1 57.6 GO:0016459 myosin complex(GO:0016459)
1.1 22.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
1.0 25.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
1.0 4.9 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.9 2.8 GO:0034686 integrin alphav-beta8 complex(GO:0034686) alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.9 9.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.9 6.3 GO:0030870 Mre11 complex(GO:0030870)
0.9 5.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.9 7.9 GO:0044327 dendritic spine head(GO:0044327)
0.9 9.5 GO:0043083 synaptic cleft(GO:0043083)
0.8 9.3 GO:0032009 early phagosome(GO:0032009)
0.8 20.7 GO:0001533 cornified envelope(GO:0001533)
0.8 14.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.8 4.8 GO:0098871 postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
0.8 4.7 GO:0032280 symmetric synapse(GO:0032280)
0.8 18.9 GO:0014704 intercalated disc(GO:0014704)
0.7 7.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.7 7.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.7 3.4 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.7 34.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.7 5.4 GO:0097443 sorting endosome(GO:0097443)
0.7 8.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.7 4.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.6 5.7 GO:0000813 ESCRT I complex(GO:0000813)
0.6 2.5 GO:0070876 SOSS complex(GO:0070876)
0.6 35.3 GO:0034707 chloride channel complex(GO:0034707)
0.6 1.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.6 5.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.6 4.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.5 3.3 GO:1990246 uniplex complex(GO:1990246)
0.5 5.4 GO:0042587 glycogen granule(GO:0042587)
0.5 13.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 5.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.5 8.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 2.7 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.5 31.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.5 4.5 GO:0031143 pseudopodium(GO:0031143)
0.4 12.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 2.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.4 7.2 GO:0036038 MKS complex(GO:0036038)
0.4 1.7 GO:0032021 NELF complex(GO:0032021)
0.4 73.9 GO:0005802 trans-Golgi network(GO:0005802)
0.4 3.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.4 3.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 4.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.4 9.9 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4 3.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.4 12.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.4 6.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4 20.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 3.1 GO:0060091 kinocilium(GO:0060091)
0.3 12.4 GO:0008180 COP9 signalosome(GO:0008180)
0.3 9.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.3 10.0 GO:0002102 podosome(GO:0002102)
0.3 105.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.3 19.7 GO:0005581 collagen trimer(GO:0005581)
0.3 3.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 2.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 8.1 GO:0044295 axonal growth cone(GO:0044295)
0.3 42.6 GO:0031966 mitochondrial membrane(GO:0031966)
0.3 19.5 GO:0005604 basement membrane(GO:0005604)
0.2 7.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 0.9 GO:0034706 sodium channel complex(GO:0034706)
0.2 16.1 GO:0005901 caveola(GO:0005901)
0.2 2.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 80.0 GO:0031012 extracellular matrix(GO:0031012)
0.2 15.9 GO:0030018 Z disc(GO:0030018)
0.2 16.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 1.4 GO:0070449 elongin complex(GO:0070449)
0.2 3.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 10.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 1.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) lumenal side of membrane(GO:0098576)
0.2 4.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 28.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 0.9 GO:0032590 dendrite membrane(GO:0032590)
0.2 2.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 23.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 2.0 GO:0034709 methylosome(GO:0034709)
0.1 1.3 GO:0032426 stereocilium tip(GO:0032426)
0.1 19.0 GO:0070382 exocytic vesicle(GO:0070382)
0.1 7.2 GO:0005902 microvillus(GO:0005902)
0.1 2.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 0.2 GO:0031309 intrinsic component of nuclear outer membrane(GO:0031308) integral component of nuclear outer membrane(GO:0031309)
0.1 1.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 3.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.2 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.2 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 1.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 5.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
24.0 96.0 GO:0099609 microtubule lateral binding(GO:0099609)
21.3 127.9 GO:0032027 myosin light chain binding(GO:0032027)
11.8 35.3 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
11.7 81.7 GO:0004111 creatine kinase activity(GO:0004111)
11.6 34.8 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
10.7 42.7 GO:0030899 troponin C binding(GO:0030172) calcium-dependent ATPase activity(GO:0030899)
8.2 65.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
7.0 42.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
6.6 106.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
6.3 25.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
6.2 43.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
5.8 29.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
5.8 23.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
5.7 28.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
5.6 22.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
5.1 20.3 GO:1904288 BAT3 complex binding(GO:1904288)
4.9 19.6 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
4.4 13.2 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
4.3 21.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
4.3 21.4 GO:0038132 neuregulin binding(GO:0038132)
4.3 161.5 GO:0008307 structural constituent of muscle(GO:0008307)
4.2 12.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
4.1 12.2 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
4.0 12.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
3.9 11.8 GO:0034437 glycoprotein transporter activity(GO:0034437)
3.9 38.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
3.7 14.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
3.7 51.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
3.7 40.2 GO:0042577 lipid phosphatase activity(GO:0042577)
3.5 14.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
3.5 38.7 GO:0004017 adenylate kinase activity(GO:0004017)
3.3 13.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
3.2 19.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
3.2 35.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
3.1 24.8 GO:0045545 syndecan binding(GO:0045545)
3.1 9.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
3.0 9.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
3.0 9.0 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
2.9 73.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
2.8 8.3 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
2.7 62.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
2.7 18.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
2.7 21.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
2.6 23.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
2.6 7.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
2.5 7.6 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827)
2.5 32.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
2.5 9.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
2.5 39.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
2.4 22.0 GO:0042285 xylosyltransferase activity(GO:0042285)
2.4 9.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
2.3 20.9 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.3 20.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
2.2 8.9 GO:0031750 D3 dopamine receptor binding(GO:0031750)
2.2 17.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.1 10.5 GO:0004977 melanocortin receptor activity(GO:0004977)
2.1 10.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
2.1 6.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
2.1 12.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
2.1 28.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
2.0 5.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.9 11.6 GO:0032407 MutSalpha complex binding(GO:0032407)
1.9 17.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.9 43.0 GO:0043274 phospholipase binding(GO:0043274)
1.8 12.8 GO:0015368 calcium:cation antiporter activity(GO:0015368)
1.7 6.9 GO:0031686 A1 adenosine receptor binding(GO:0031686)
1.7 8.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.7 8.3 GO:0070052 collagen V binding(GO:0070052)
1.7 13.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
1.6 6.5 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
1.6 3.3 GO:0015292 uniporter activity(GO:0015292)
1.6 4.8 GO:0004946 bombesin receptor activity(GO:0004946)
1.6 6.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.6 4.7 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.5 4.5 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
1.5 4.5 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698) histone kinase activity (H3-T6 specific)(GO:0035403)
1.5 13.1 GO:0015450 protein channel activity(GO:0015266) P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.4 4.3 GO:0048495 Roundabout binding(GO:0048495)
1.4 26.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.4 4.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
1.4 6.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105) type 2 fibroblast growth factor receptor binding(GO:0005111)
1.3 10.7 GO:0016421 CoA carboxylase activity(GO:0016421)
1.3 6.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.3 16.0 GO:0030215 semaphorin receptor binding(GO:0030215)
1.3 11.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.3 22.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
1.3 35.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.2 3.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
1.2 13.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
1.1 23.8 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.1 13.5 GO:0033691 sialic acid binding(GO:0033691)
1.1 3.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.1 5.6 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
1.1 15.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
1.1 5.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.1 7.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.1 6.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
1.1 12.9 GO:0070324 thyroid hormone binding(GO:0070324)
1.1 5.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
1.1 7.4 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
1.0 27.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.0 5.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.0 20.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.0 40.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
1.0 23.7 GO:0008308 voltage-gated anion channel activity(GO:0008308)
1.0 7.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.0 14.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.9 9.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.9 18.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.9 2.8 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.9 4.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.9 3.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.9 4.5 GO:0005042 netrin receptor activity(GO:0005042)
0.9 18.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.9 3.5 GO:0051870 methotrexate binding(GO:0051870)
0.8 8.5 GO:0019841 retinol binding(GO:0019841)
0.8 11.6 GO:0051378 serotonin binding(GO:0051378)
0.8 6.6 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.8 14.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.8 4.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.8 4.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.8 5.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.7 6.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.7 8.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.7 3.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.7 12.1 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.7 4.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.7 3.4 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.7 7.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.7 5.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.7 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.7 15.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.7 9.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.7 3.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.6 4.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.6 1.3 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.6 6.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.6 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.6 9.0 GO:0005523 tropomyosin binding(GO:0005523)
0.6 15.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.6 38.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.6 1.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.6 13.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.6 5.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.6 2.8 GO:0050692 DBD domain binding(GO:0050692)
0.6 1.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.6 4.5 GO:0003680 AT DNA binding(GO:0003680)
0.6 12.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 3.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.5 8.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.5 5.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 2.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.5 8.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 10.7 GO:0071837 HMG box domain binding(GO:0071837)
0.5 7.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.5 7.9 GO:0070300 phosphatidic acid binding(GO:0070300)
0.5 11.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.5 2.4 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.5 1.9 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.5 5.1 GO:0045499 chemorepellent activity(GO:0045499)
0.5 9.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.5 2.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.5 0.9 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.5 2.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5 8.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4 2.6 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.4 1.3 GO:0016509 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4 4.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.4 2.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 2.9 GO:0008430 selenium binding(GO:0008430)
0.4 24.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 10.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.4 3.8 GO:0042301 phosphate ion binding(GO:0042301)
0.4 3.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 1.1 GO:0004956 prostaglandin D receptor activity(GO:0004956)
0.3 2.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 41.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 1.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 5.6 GO:0097602 cullin family protein binding(GO:0097602)
0.3 1.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.3 8.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 1.6 GO:0004103 choline kinase activity(GO:0004103)
0.3 4.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.3 1.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 7.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.3 1.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 1.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.3 3.9 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.3 8.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 7.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 174.1 GO:0005509 calcium ion binding(GO:0005509)
0.3 15.8 GO:0005518 collagen binding(GO:0005518)
0.2 6.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 1.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.2 2.5 GO:0070097 delta-catenin binding(GO:0070097)
0.2 3.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 5.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 2.9 GO:0031005 filamin binding(GO:0031005)
0.2 64.9 GO:0030695 GTPase regulator activity(GO:0030695)
0.2 12.3 GO:0019894 kinesin binding(GO:0019894)
0.2 10.5 GO:0005262 calcium channel activity(GO:0005262)
0.2 1.5 GO:0031402 sodium ion binding(GO:0031402)
0.2 1.7 GO:0015250 water channel activity(GO:0015250)
0.2 2.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 8.6 GO:0070330 aromatase activity(GO:0070330)
0.2 4.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 3.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 1.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 7.0 GO:0008009 chemokine activity(GO:0008009)
0.2 3.7 GO:0030276 clathrin binding(GO:0030276)
0.2 4.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 4.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 4.9 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2 1.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 1.8 GO:0001618 virus receptor activity(GO:0001618)
0.2 1.0 GO:0051920 peroxiredoxin activity(GO:0051920)
0.2 9.5 GO:0002039 p53 binding(GO:0002039)
0.2 2.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 51.4 GO:0003779 actin binding(GO:0003779)
0.2 5.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 10.1 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.6 GO:0032564 dATP binding(GO:0032564)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 8.8 GO:0001948 glycoprotein binding(GO:0001948)
0.1 0.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.5 GO:0005272 sodium channel activity(GO:0005272)
0.1 3.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 10.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 5.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 1.9 GO:0030332 cyclin binding(GO:0030332)
0.1 7.5 GO:0004540 ribonuclease activity(GO:0004540)
0.1 1.1 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 5.9 GO:0005496 steroid binding(GO:0005496)
0.1 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 28.5 GO:0005549 odorant binding(GO:0005549)
0.1 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 3.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 2.3 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.1 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.0 1.4 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 27.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 96.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
2.5 64.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
1.6 76.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.4 23.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.2 243.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
1.1 12.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
1.0 63.9 PID LKB1 PATHWAY LKB1 signaling events
1.0 32.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.9 4.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.9 33.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.9 38.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.8 38.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.8 15.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.8 24.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.8 6.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.7 61.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.7 11.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.7 12.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.6 12.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.6 37.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.6 14.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.5 11.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.4 7.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.4 26.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.4 6.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.4 4.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3 4.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 12.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.3 9.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.3 7.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 6.3 PID RAS PATHWAY Regulation of Ras family activation
0.3 3.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 3.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 9.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 6.1 PID FGF PATHWAY FGF signaling pathway
0.2 32.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 11.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 3.6 PID ARF 3PATHWAY Arf1 pathway
0.2 2.0 PID BARD1 PATHWAY BARD1 signaling events
0.2 3.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.2 3.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 8.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 28.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 4.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 3.0 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 133.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
2.5 99.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
2.5 37.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
2.5 69.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
2.4 43.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
2.0 32.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.9 38.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.9 46.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.8 22.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
1.7 22.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
1.6 14.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
1.4 30.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.2 53.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
1.2 40.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
1.1 4.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
1.0 30.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.0 13.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.0 33.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.9 13.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.9 28.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.9 27.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.8 11.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.8 8.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.8 19.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.7 34.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.7 17.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.6 8.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.6 12.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.6 10.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.6 2.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.6 13.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.6 9.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.6 24.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.6 10.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.5 9.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.5 8.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 37.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.5 11.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.5 14.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.5 5.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.5 5.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 6.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 4.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 24.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 4.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.3 5.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 4.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 5.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 7.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.3 2.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 2.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 22.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 49.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.3 7.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 6.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 2.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.3 19.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.3 9.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 3.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 31.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 4.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 4.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 5.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 12.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 1.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 2.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 4.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.0 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 2.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 2.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL