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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hlf

Z-value: 0.88

Motif logo

Transcription factors associated with Hlf

Gene Symbol Gene ID Gene Info
ENSRNOG00000002456 HLF, PAR bZIP transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hlfrn6_v1_chr10_-_77918191_77918191-0.009.3e-01Click!

Activity profile of Hlf motif

Sorted Z-values of Hlf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_248428099 56.34 ENSRNOT00000050984
mannose binding lectin 2
chr11_-_81660395 32.56 ENSRNOT00000048739
fetuin B
chr1_+_83103925 30.02 ENSRNOT00000047540
ENSRNOT00000028196
cytochrome P450, family 2, subfamily b, polypeptide 2
chr1_+_83653234 27.98 ENSRNOT00000085008
ENSRNOT00000084230
ENSRNOT00000090071
cytochrome P450, family 2, subfamily a, polypeptide 1
chr19_+_15195565 27.80 ENSRNOT00000090865
ENSRNOT00000078874
carboxylesterase 1D
chr19_+_15033108 26.66 ENSRNOT00000021812
carboxylesterase 1D
chr4_-_176679815 22.69 ENSRNOT00000090122
glycogen synthase 2
chr11_-_81639872 22.26 ENSRNOT00000047595
ENSRNOT00000090031
ENSRNOT00000081864
histidine-rich glycoprotein
chr7_+_99142450 21.59 ENSRNOT00000079036
ENSRNOT00000091923
cytochrome P450 2B1
chr1_+_83163079 20.32 ENSRNOT00000077725
ENSRNOT00000034845
cytochrome P450, family 2, subfamily b, polypeptide 3
chr3_-_37803112 20.19 ENSRNOT00000059461
nebulin
chr13_-_57080491 19.81 ENSRNOT00000017749
ENSRNOT00000086572
ENSRNOT00000060111
complement factor H
chr8_+_116857684 19.24 ENSRNOT00000026711
macrophage stimulating 1
chr1_+_193424812 18.96 ENSRNOT00000019939
aquaporin 8
chr14_+_84306466 18.60 ENSRNOT00000006116
SEC14-like lipid binding 4
chr9_-_78969013 16.26 ENSRNOT00000019772
ENSRNOT00000057585
fibronectin 1
chr2_+_193627243 15.54 ENSRNOT00000082934

chr12_+_19196611 15.45 ENSRNOT00000001801
alpha-2-glycoprotein 1, zinc-binding
chr7_+_40318490 15.20 ENSRNOT00000081374
similar to hypothetical protein FLJ35821
chr5_+_79179417 14.30 ENSRNOT00000010454
orosomucoid 1
chr6_+_56846789 14.20 ENSRNOT00000032108
alkylglycerol monooxygenase
chr1_+_72889270 13.94 ENSRNOT00000058843
ENSRNOT00000034957
troponin T1, slow skeletal type
chr11_+_64882288 13.57 ENSRNOT00000077727
phospholipase A1 member A
chr1_-_101596822 13.36 ENSRNOT00000028490
fibroblast growth factor 21
chr1_-_256813711 12.85 ENSRNOT00000021055
retinol binding protein 4
chr10_+_57239993 12.74 ENSRNOT00000067919
hypothetical protein LOC687707
chr7_+_93975451 12.36 ENSRNOT00000011379
collectin subfamily member 10
chrX_+_143097525 12.00 ENSRNOT00000004559
coagulation factor IX
chr3_-_153952108 11.94 ENSRNOT00000050465
adipogenin
chr11_+_62584959 11.48 ENSRNOT00000071065
GRAM domain containing 1C
chr2_+_35977828 11.31 ENSRNOT00000076712
serine protease inhibitor Kazal-type 5-like
chr1_-_259287684 10.95 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr14_+_17228856 10.76 ENSRNOT00000003082
C-X-C motif chemokine ligand 9
chr2_-_53300404 10.73 ENSRNOT00000088876
growth hormone receptor
chr5_-_146446227 10.70 ENSRNOT00000044868
high-mobility group box 4
chr5_-_39611053 10.65 ENSRNOT00000046595
four and a half LIM domains 5
chr1_-_22661377 10.16 ENSRNOT00000021896
vanin 3
chr5_-_119564846 9.90 ENSRNOT00000012977
cytochrome P450, family 2, subfamily j, polypeptide 4
chr13_-_111972603 9.76 ENSRNOT00000007870
hydroxysteroid 11-beta dehydrogenase 1
chr4_-_13878126 9.75 ENSRNOT00000007032
G protein subunit alpha transducin 3
chrX_+_78769419 9.71 ENSRNOT00000003190
T-box 22
chr9_+_20004280 9.33 ENSRNOT00000075670
ankyrin repeat domain 66
chr1_-_4550768 9.31 ENSRNOT00000061954
androglobin
chr10_-_46404642 9.31 ENSRNOT00000083698
phosphatidylethanolamine N-methyltransferase
chr10_+_94192556 9.28 ENSRNOT00000074007
ENSRNOT00000093039
angiotensin I converting enzyme (peptidyl-dipeptidase A) 3
chr7_+_18310624 9.08 ENSRNOT00000075258
actin-like 9
chr6_-_41870046 9.04 ENSRNOT00000005863
lipin 1
chr1_-_89369960 8.92 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr8_-_59849427 8.70 ENSRNOT00000020332
ENSRNOT00000083900
neuregulin 4
chr4_+_10295122 8.60 ENSRNOT00000017374
coiled-coil domain containing 146
chr2_-_233743866 8.37 ENSRNOT00000087062
glutamyl aminopeptidase
chr16_-_29936307 8.28 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr10_-_15125408 8.24 ENSRNOT00000026395
mesothelin
chrX_-_139329975 8.07 ENSRNOT00000086405
high mobility group protein B4-like
chr11_-_28900376 8.05 ENSRNOT00000061606
keratin associated protein 16-5
chr1_+_53531076 8.00 ENSRNOT00000018015
t-complex protein 10b
chr4_-_22307453 7.95 ENSRNOT00000047126
ATP binding cassette subfamily B member 1A
chr1_+_229039889 7.79 ENSRNOT00000054800
glycine-N-acyltransferase-like 1
chr4_+_157107469 7.78 ENSRNOT00000015678
complement C1r subcomponent like
chr1_-_276228574 7.67 ENSRNOT00000021746
guanylate cyclase 2G
chr13_-_84759098 7.55 ENSRNOT00000058683
similar to flavin containing monooxygenase 5
chrX_-_130794673 7.54 ENSRNOT00000080612
similar to RIKEN cDNA 1700001F22
chr10_+_70884531 7.47 ENSRNOT00000015199
C-C motif chemokine ligand 4
chr9_+_37462693 7.39 ENSRNOT00000016316
lengsin, lens protein with glutamine synthetase domain
chr2_-_186333805 7.37 ENSRNOT00000022150
CD1d1 molecule
chr12_+_38965063 7.31 ENSRNOT00000074936
MORN repeat containing 3
chr16_-_40025401 7.30 ENSRNOT00000066639
ankyrin repeat and SOCS box-containing 5
chr2_+_187275120 7.16 ENSRNOT00000017234
hepatoma-derived growth factor
chr18_+_16590197 7.00 ENSRNOT00000066583
molybdenum cofactor sulfurase
chr1_-_91296656 6.99 ENSRNOT00000028703
CCAAT/enhancer binding protein gamma
chr5_+_73496027 6.94 ENSRNOT00000022395
actin-like 7a
chrX_-_132424746 6.91 ENSRNOT00000087819
similar to RIKEN cDNA 1700001F22
chr8_-_115274165 6.82 ENSRNOT00000056386
IQ domain-containing protein F5-like
chr1_+_101603222 6.74 ENSRNOT00000033278
izumo sperm-egg fusion 1
chr18_-_29562153 6.67 ENSRNOT00000023977
CD14 molecule
chr10_-_75120247 6.66 ENSRNOT00000011402
lactoperoxidase
chr5_+_59452348 6.59 ENSRNOT00000019887
calicin
chr18_+_79773608 6.57 ENSRNOT00000088484
zinc finger protein 516
chr11_+_17538063 6.56 ENSRNOT00000031889
ENSRNOT00000090878
chondrolectin
chr6_+_1657331 6.56 ENSRNOT00000049672
ENSRNOT00000079864
glutaminyl-peptide cyclotransferase
chr11_-_17119582 6.52 ENSRNOT00000087665
similar to DNA segment, Chr 16, ERATO Doi 472, expressed
chr10_-_89699836 6.49 ENSRNOT00000084311
ets variant 4
chr4_-_69163881 6.48 ENSRNOT00000048779
trypsin X5
chr10_+_55626741 6.44 ENSRNOT00000008492
aurora kinase B
chr3_-_110021149 6.43 ENSRNOT00000007808
fibrous sheath interacting protein 1
chr8_+_115213471 6.38 ENSRNOT00000017570
IQ motif containing F5
chr1_+_99781237 6.33 ENSRNOT00000025489
kallikrein related-peptidase 5
chrX_+_159165169 6.31 ENSRNOT00000087274
four and a half LIM domains 1
chr1_+_167309051 6.28 ENSRNOT00000055235
ENSRNOT00000076894
post-GPI attachment to proteins 2
chr1_+_99648658 6.21 ENSRNOT00000039531
kallikrein related-peptidase 13
chr4_-_176528110 6.20 ENSRNOT00000049569
solute carrier organic anion transporter family, member 1A2
chr8_-_61519507 6.18 ENSRNOT00000038347
outer dense fiber of sperm tails 3-like 1
chrX_-_144001727 6.12 ENSRNOT00000078404
similar to RIKEN cDNA 1700001F22
chr11_-_34598102 6.09 ENSRNOT00000068743
phosphatidylinositol glycan anchor biosynthesis, class P
chr10_+_69434941 6.08 ENSRNOT00000009756
C-C motif chemokine ligand 11
chr5_+_48303366 5.95 ENSRNOT00000009973
gamma-aminobutyric acid type A receptor rho 2 subunit
chr18_+_16590408 5.95 ENSRNOT00000093715
molybdenum cofactor sulfurase
chr5_-_104920906 5.89 ENSRNOT00000071318
family with sequence similarity 154, member A
chr5_-_172078760 5.89 ENSRNOT00000016781
actin-related protein T2
chrX_-_158261717 5.87 ENSRNOT00000086804
similar to RIKEN cDNA 1700001F22
chr8_-_14157141 5.87 ENSRNOT00000079034
deuterosome assembly protein 1
chr16_-_31301880 5.84 ENSRNOT00000084847
ENSRNOT00000083943

chr7_-_70355619 5.84 ENSRNOT00000031272
tetraspanin 31
chrX_+_137197396 5.78 ENSRNOT00000082227
similar to RIKEN cDNA 1700001F22
chr13_-_105684374 5.59 ENSRNOT00000073142
spermatogenesis associated 17
chr8_-_17524839 5.46 ENSRNOT00000081679
N-acetylated alpha-linked acidic dipeptidase 2
chr7_+_141054494 5.45 ENSRNOT00000088176
transmembrane BAX inhibitor motif containing 6
chr8_+_4085829 5.42 ENSRNOT00000031286
actin-like 9b
chr10_-_89700283 5.41 ENSRNOT00000028213
ets variant 4
chr1_+_277641512 5.40 ENSRNOT00000084861
ENSRNOT00000023024
tudor domain containing 1
chr10_+_75620470 5.35 ENSRNOT00000013882
coiled-coil domain containing 182
chr11_-_34598275 5.26 ENSRNOT00000077233
phosphatidylinositol glycan anchor biosynthesis, class P
chr11_-_79703736 5.26 ENSRNOT00000044279
LIM domain containing preferred translocation partner in lipoma
chr9_-_113358526 5.20 ENSRNOT00000065073
thioredoxin domain containing 2
chr1_+_250426158 5.15 ENSRNOT00000067643
APOBEC1 complementation factor
chr2_-_164684985 4.99 ENSRNOT00000057504
retinoic acid receptor responder 1
chr2_+_76923591 4.92 ENSRNOT00000042759
signal-regulatory protein alpha-like
chr9_-_20219209 4.90 ENSRNOT00000072086
SPRY domain-containing SOCS box protein 2-like
chr7_+_18668692 4.86 ENSRNOT00000009532
KN motif and ankyrin repeat domains 3
chr13_+_27449934 4.81 ENSRNOT00000003409
serpin family B member 2
chr16_-_82288022 4.71 ENSRNOT00000078609
sperm acrosome associated 7
chr18_+_45023932 4.64 ENSRNOT00000039379
family with sequence similarity 170, member A
chr2_-_192671059 4.62 ENSRNOT00000012174
small proline-rich protein 1A
chr8_-_105226588 4.61 ENSRNOT00000071936
tripartite motif-containing 42
chr4_+_70977556 4.55 ENSRNOT00000031984
hypothetical protein LOC680112
chr15_-_28155291 4.52 ENSRNOT00000050820
ribonuclease A family member 2
chr7_+_60015998 4.43 ENSRNOT00000007309
bestrophin 3
chr7_-_77159457 4.42 ENSRNOT00000085626
Kruppel-like factor 10
chr5_-_7941822 4.41 ENSRNOT00000079917
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chrX_+_110233170 4.40 ENSRNOT00000036019
RIKEN cDNA 4930513O06 gene
chr1_-_89190128 4.39 ENSRNOT00000067813
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr6_+_43743702 4.33 ENSRNOT00000082570
grainyhead-like transcription factor 1
chr3_-_74597393 4.31 ENSRNOT00000013201
olfactory receptor 536
chr18_-_77322690 4.29 ENSRNOT00000058382
nuclear factor of activated T-cells 1
chr11_-_27080701 4.27 ENSRNOT00000002180
listerin E3 ubiquitin protein ligase 1
chrX_+_106774980 4.26 ENSRNOT00000046091
transcription elongation factor A like 7
chr1_-_22559830 4.23 ENSRNOT00000047810
trace amine-associated receptor 4
chr17_+_85382116 4.22 ENSRNOT00000002513
sperm associated antigen 6
chrX_-_26376467 4.18 ENSRNOT00000051655
ENSRNOT00000036502
Rho GTPase activating protein 6
chr13_+_82479998 4.18 ENSRNOT00000079872
coagulation factor V
chr16_+_61954809 4.14 ENSRNOT00000068011
RNA binding protein with multiple splicing
chr4_-_169036950 4.13 ENSRNOT00000011295
germ cell associated 1
chr2_+_189413966 4.03 ENSRNOT00000056603
RGD1564171
chr19_-_57333433 4.02 ENSRNOT00000024917
angiotensinogen
chr4_-_163402561 3.93 ENSRNOT00000091890
killer cell lectin like receptor K1
chr3_+_170475831 3.93 ENSRNOT00000006949
family with sequence similarity 209, member A
chr4_+_157326727 3.87 ENSRNOT00000020493
splA/ryanodine receptor domain and SOCS box containing 2
chrX_-_143558521 3.82 ENSRNOT00000056598
hypothetical protein LOC688842
chr8_+_65733400 3.81 ENSRNOT00000089126
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_+_101882994 3.78 ENSRNOT00000087773

chr5_-_78376032 3.74 ENSRNOT00000075916
aminolevulinate dehydratase
chr16_-_49522341 3.74 ENSRNOT00000081642
coiled-coil domain-containing protein 110-like
chr16_+_54291251 3.71 ENSRNOT00000079006
microtubule associated tumor suppressor 1
chr2_+_150106292 3.66 ENSRNOT00000073078
arylacetamide deacetylase-like 2-like
chr8_-_36764422 3.65 ENSRNOT00000017330
HYLS1, centriolar and ciliogenesis associated
chr14_+_35683442 3.61 ENSRNOT00000003085
cysteine-rich hydrophobic domain 2
chr3_+_19274273 3.57 ENSRNOT00000040102

chr20_-_2088389 3.53 ENSRNOT00000090910
ZNRD1 antisense RNA 1
chr20_-_10844178 3.50 ENSRNOT00000079207
heat shock transcription factor 2 binding protein
chr10_-_87954055 3.48 ENSRNOT00000018048
keratin 34
chr16_-_70998575 3.38 ENSRNOT00000019935
potassium calcium-activated channel subfamily U member 1
chr4_-_168517177 3.38 ENSRNOT00000009151
dual specificity phosphatase 16
chr2_+_150344307 3.37 ENSRNOT00000072617
arylacetamide deacetylase-like 2
chr18_-_28301863 3.35 ENSRNOT00000026895
SIL1 nucleotide exchange factor
chr3_+_93968855 3.33 ENSRNOT00000014478
F-box protein 3
chr18_+_52459108 3.29 ENSRNOT00000040657
uncharacterized LOC100910150
chr15_-_41595345 3.26 ENSRNOT00000019639
sarcoglycan, gamma
chr1_+_198089446 3.26 ENSRNOT00000026146
SAGA complex associated factor 29
chr8_+_99636749 3.25 ENSRNOT00000086524
phospholipid scramblase 1
chr1_-_167308827 3.24 ENSRNOT00000027590
ENSRNOT00000027575
nucleoporin 98
chr13_+_100214353 3.23 ENSRNOT00000073693
hypothetical protein LOC686031
chr2_-_173668555 3.23 ENSRNOT00000013452
serpin family I member 2
chr5_+_153845094 3.23 ENSRNOT00000041600
sperm-tail PG-rich repeat containing 1
chrX_-_43878881 3.21 ENSRNOT00000066493
claudin 34D
chr20_+_22728208 3.21 ENSRNOT00000000794
nuclear receptor-binding factor 2-like
chr4_+_70572942 3.21 ENSRNOT00000051964

chr1_+_83626639 3.20 ENSRNOT00000028261
cytochrome P450, family 2, subfamily g, polypeptide 1
chr7_-_18793289 3.19 ENSRNOT00000036375

chr7_-_2941122 3.19 ENSRNOT00000082107
extended synaptotagmin 1
chr13_-_98078946 3.16 ENSRNOT00000035875
AT hook containing transcription factor 1
chr2_-_205212681 3.16 ENSRNOT00000022575
thyroid stimulating hormone, beta
chr4_-_163049084 3.12 ENSRNOT00000091644
Cd69 molecule
chr4_+_181243338 3.11 ENSRNOT00000034051
single-pass membrane protein with coiled-coil domains 2
chrX_-_77418525 3.11 ENSRNOT00000092303
fibronectin type III domain containing 3C1
chr3_+_138974871 3.08 ENSRNOT00000012524
SCP2 sterol-binding domain containing 1
chr1_-_167700332 3.05 ENSRNOT00000092890
tripartite motif-containing 21
chr20_+_5262120 3.01 ENSRNOT00000000535
bromodomain containing 2
chr10_-_87503591 3.00 ENSRNOT00000037980
keratin associated protein 1-1
chr4_-_163403653 2.99 ENSRNOT00000088151
killer cell lectin like receptor K1
chr3_+_143129248 2.94 ENSRNOT00000006667
cystatin 8
chr1_-_178218761 2.92 ENSRNOT00000019199
parathyroid hormone
chr4_-_17440506 2.92 ENSRNOT00000080931
semaphorin 3E
chr1_+_227592635 2.90 ENSRNOT00000072135
membrane-spanning 4-domains, subfamily A, member 4A
chr11_+_60336061 2.85 ENSRNOT00000084022
similar to OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen)
chr3_-_175601127 2.84 ENSRNOT00000081226
laminin subunit alpha 5
chr9_+_112360419 2.82 ENSRNOT00000086682
mannosidase, alpha, class 2A, member 1
chr4_+_112773938 2.77 ENSRNOT00000009321
eva-1 homolog A, regulator of programmed cell death
chr5_-_117440254 2.74 ENSRNOT00000066139
KN motif and ankyrin repeat domains 4
chr5_+_151181559 2.74 ENSRNOT00000085674
FGR proto-oncogene, Src family tyrosine kinase
chr10_-_6870011 2.74 ENSRNOT00000003439
similar to CG4768-PA

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
18.2 54.5 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
14.1 56.3 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
7.4 22.3 GO:0097037 heme export(GO:0097037)
5.4 16.3 GO:0052047 calcium-independent cell-matrix adhesion(GO:0007161) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) regulation of transforming growth factor-beta secretion(GO:2001201)
4.6 13.9 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
4.3 12.8 GO:0046865 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
4.0 28.0 GO:0009804 coumarin metabolic process(GO:0009804)
3.4 77.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
3.3 9.8 GO:0006713 glucocorticoid catabolic process(GO:0006713)
2.8 25.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
2.7 19.0 GO:0015722 canalicular bile acid transport(GO:0015722)
2.7 13.4 GO:1904640 response to methionine(GO:1904640)
2.5 7.4 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
2.3 6.9 GO:2000502 stimulatory C-type lectin receptor signaling pathway(GO:0002223) negative regulation of natural killer cell chemotaxis(GO:2000502)
2.2 8.9 GO:0034760 negative regulation of iron ion transmembrane transport(GO:0034760) cellular response to bile acid(GO:1903413)
2.2 6.6 GO:0018199 peptidyl-glutamine modification(GO:0018199)
2.1 17.0 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
2.0 4.0 GO:1903598 angiotensin-mediated drinking behavior(GO:0003051) positive regulation of gap junction assembly(GO:1903598)
2.0 8.0 GO:1990962 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) response to cyclosporin A(GO:1905237) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
1.8 5.5 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.7 11.9 GO:0060762 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.7 8.4 GO:0002003 angiotensin maturation(GO:0002003)
1.6 9.7 GO:0050917 sensory perception of umami taste(GO:0050917)
1.6 9.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
1.4 19.8 GO:0030449 regulation of complement activation(GO:0030449)
1.4 5.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.3 9.0 GO:0006642 triglyceride mobilization(GO:0006642)
1.3 5.2 GO:0016554 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) cytidine to uridine editing(GO:0016554)
1.3 2.5 GO:0060300 regulation of cytokine activity(GO:0060300)
1.3 6.3 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
1.2 7.5 GO:0035747 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
1.2 10.7 GO:0072338 allantoin metabolic process(GO:0000255) isoleucine metabolic process(GO:0006549) creatine metabolic process(GO:0006600) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
1.2 14.2 GO:0046485 ether lipid metabolic process(GO:0046485)
1.2 13.0 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
1.2 5.9 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
1.1 3.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.1 4.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
1.0 2.1 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
1.0 5.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
1.0 39.3 GO:0035036 sperm-egg recognition(GO:0035036)
0.9 7.0 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.9 6.8 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.9 22.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.7 6.7 GO:0071724 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.7 2.9 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.7 2.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.7 12.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.7 2.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.7 2.0 GO:0051012 microtubule sliding(GO:0051012)
0.7 2.0 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.6 1.9 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
0.6 3.7 GO:0010266 response to vitamin B1(GO:0010266) response to platinum ion(GO:0070541)
0.6 6.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.6 1.7 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.5 4.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.5 4.2 GO:0032571 response to vitamin K(GO:0032571)
0.5 1.5 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.5 17.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.5 5.9 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.5 3.3 GO:0070782 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) phosphatidylserine exposure on apoptotic cell surface(GO:0070782) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.5 7.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 3.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 5.5 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.4 1.2 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.4 22.2 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.4 2.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.4 4.3 GO:0002934 desmosome organization(GO:0002934)
0.4 3.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.4 4.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.4 1.1 GO:0006738 nicotinamide riboside catabolic process(GO:0006738) urate biosynthetic process(GO:0034418) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.3 2.7 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.3 2.4 GO:0007343 egg activation(GO:0007343)
0.3 2.7 GO:0033483 regulation of protein ADP-ribosylation(GO:0010835) gas homeostasis(GO:0033483)
0.3 1.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.3 5.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.3 1.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3 7.4 GO:0006541 glutamine metabolic process(GO:0006541)
0.3 4.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.3 0.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.3 1.1 GO:0045423 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.3 2.4 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 2.8 GO:0006013 mannose metabolic process(GO:0006013)
0.2 1.7 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.2 2.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 1.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 1.8 GO:0016584 maintenance of DNA methylation(GO:0010216) nucleosome positioning(GO:0016584)
0.2 4.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.2 4.6 GO:0031424 keratinization(GO:0031424)
0.2 2.1 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.2 2.6 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.2 1.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 2.0 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.2 4.2 GO:0007635 chemosensory behavior(GO:0007635)
0.2 8.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.2 2.7 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2 2.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.2 2.5 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.2 2.9 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.2 1.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 4.4 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.2 1.6 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 0.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.3 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 6.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 2.3 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.4 GO:0009609 response to symbiotic bacterium(GO:0009609)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 1.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 3.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 6.0 GO:0060612 adipose tissue development(GO:0060612)
0.1 2.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.6 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 3.8 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.1 1.0 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 3.2 GO:0033189 response to vitamin A(GO:0033189)
0.1 2.1 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 4.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 8.6 GO:0031638 zymogen activation(GO:0031638)
0.1 1.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 3.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 3.0 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 1.0 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 3.6 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 0.9 GO:0010225 response to UV-C(GO:0010225)
0.1 0.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 3.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 4.4 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.0 7.3 GO:0006575 cellular modified amino acid metabolic process(GO:0006575)
0.0 5.0 GO:0016485 protein processing(GO:0016485)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 2.8 GO:0008037 cell recognition(GO:0008037)
0.0 0.8 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.9 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 3.2 GO:0006869 lipid transport(GO:0006869)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.9 GO:0006757 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.2 GO:0030953 astral microtubule organization(GO:0030953)
0.0 3.9 GO:0016042 lipid catabolic process(GO:0016042)
0.0 1.3 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.5 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 19.0 GO:0046691 intracellular canaliculus(GO:0046691)
5.6 22.3 GO:0061474 phagolysosome membrane(GO:0061474)
2.1 10.7 GO:0070195 growth hormone receptor complex(GO:0070195)
2.0 16.3 GO:0005577 fibrinogen complex(GO:0005577)
1.3 6.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.3 11.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.2 5.9 GO:0098536 deuterosome(GO:0098536)
1.2 13.9 GO:0005861 troponin complex(GO:0005861)
1.1 6.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.9 5.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.9 69.8 GO:0005581 collagen trimer(GO:0005581)
0.8 8.3 GO:0045179 apical cortex(GO:0045179)
0.8 9.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.8 3.8 GO:0043293 apoptosome(GO:0043293)
0.7 60.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.7 20.3 GO:0002080 acrosomal membrane(GO:0002080)
0.7 2.8 GO:0043259 laminin-10 complex(GO:0043259)
0.6 8.4 GO:0031983 vesicle lumen(GO:0031983)
0.6 8.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.6 5.4 GO:0071546 pi-body(GO:0071546)
0.6 1.7 GO:0071942 XPC complex(GO:0071942)
0.5 3.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 1.3 GO:0005745 m-AAA complex(GO:0005745)
0.3 39.9 GO:0072562 blood microparticle(GO:0072562)
0.3 7.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 35.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 22.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 6.9 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 2.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 4.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.3 5.2 GO:0001520 outer dense fiber(GO:0001520)
0.3 6.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.3 2.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 2.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 1.5 GO:0045293 mRNA editing complex(GO:0045293)
0.2 4.1 GO:0005685 U1 snRNP(GO:0005685)
0.2 4.6 GO:0001533 cornified envelope(GO:0001533)
0.2 121.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.2 1.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 2.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.3 GO:0070652 HAUS complex(GO:0070652)
0.1 168.1 GO:0005615 extracellular space(GO:0005615)
0.1 2.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0097413 Lewy body(GO:0097413)
0.1 4.3 GO:0016235 aggresome(GO:0016235)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 7.8 GO:0005814 centriole(GO:0005814)
0.1 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.1 3.2 GO:0005882 intermediate filament(GO:0005882)
0.0 3.0 GO:0045095 keratin filament(GO:0045095)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 10.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 3.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.6 GO:1902911 protein kinase complex(GO:1902911)
0.0 8.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0030286 dynein complex(GO:0030286)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
13.6 54.5 GO:0004771 sterol esterase activity(GO:0004771)
11.3 56.3 GO:0005534 galactose binding(GO:0005534)
3.5 105.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
3.3 9.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
3.2 13.0 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
2.7 19.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
2.7 10.7 GO:0004903 growth hormone receptor activity(GO:0004903)
2.3 14.0 GO:0071723 lipopeptide binding(GO:0071723)
2.3 16.3 GO:0045340 mercury ion binding(GO:0045340)
2.3 9.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
2.3 13.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
2.2 10.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
2.0 6.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
2.0 13.9 GO:0031014 troponin T binding(GO:0031014)
1.9 11.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.8 42.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.7 20.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
1.6 11.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
1.6 8.0 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.4 5.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.4 19.0 GO:0015250 water channel activity(GO:0015250)
1.3 7.8 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
1.2 3.7 GO:0004655 porphobilinogen synthase activity(GO:0004655)
1.2 7.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.1 11.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.1 4.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.1 4.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
1.0 4.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.0 12.8 GO:0019841 retinol binding(GO:0019841)
0.9 2.6 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.8 3.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.8 6.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.7 21.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.7 2.0 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.7 12.4 GO:0005537 mannose binding(GO:0005537)
0.6 5.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.6 7.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 1.5 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.5 1.9 GO:0070052 collagen V binding(GO:0070052)
0.5 2.7 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.4 7.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.4 15.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 4.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.4 13.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 4.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.4 2.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.4 9.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 2.5 GO:0036122 BMP binding(GO:0036122)
0.4 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 5.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.4 1.1 GO:0002060 purine nucleobase binding(GO:0002060) purine-nucleoside phosphorylase activity(GO:0004731)
0.3 7.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 9.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3 8.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 5.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.0 GO:0032427 GBD domain binding(GO:0032427)
0.3 7.0 GO:0008301 DNA binding, bending(GO:0008301)
0.3 1.5 GO:0019862 IgA binding(GO:0019862)
0.3 6.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 6.6 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.3 59.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 1.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 1.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 6.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 3.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 6.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 3.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 13.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.2 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 2.9 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 0.3 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.2 2.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 3.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 2.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 3.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 1.1 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.1 GO:0035375 zymogen binding(GO:0035375)
0.1 2.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 3.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 2.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 3.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.3 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
0.1 1.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 5.8 GO:0005507 copper ion binding(GO:0005507)
0.1 7.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 5.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 2.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 5.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.6 GO:0008097 5S rRNA binding(GO:0008097)
0.0 6.9 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 4.5 GO:0004519 endonuclease activity(GO:0004519)
0.0 6.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.4 GO:0008061 chitin binding(GO:0008061)
0.0 2.4 GO:0002020 protease binding(GO:0002020)
0.0 3.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 5.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 16.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5 9.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.5 22.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.5 70.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 18.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.3 3.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 2.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 6.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 2.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 14.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 3.0 PID IL23 PATHWAY IL23-mediated signaling events
0.2 5.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 4.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 10.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 2.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 35.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 5.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 4.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 56.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.6 19.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.4 19.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.3 12.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.9 16.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.9 34.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.7 6.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.6 6.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.6 11.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.6 14.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.5 4.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 19.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 8.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.3 9.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.3 3.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 21.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.3 4.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.3 22.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 7.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 3.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 6.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 5.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 9.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 5.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 6.0 REACTOME GABA RECEPTOR ACTIVATION Genes involved in GABA receptor activation
0.1 2.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 2.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 6.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 3.7 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation