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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Mybl2

Z-value: 1.40

Motif logo

Transcription factors associated with Mybl2

Gene Symbol Gene ID Gene Info
ENSRNOG00000007805 myeloblastosis oncogene-like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mybl2rn6_v1_chr3_+_159421671_1594216710.383.8e-12Click!

Activity profile of Mybl2 motif

Sorted Z-values of Mybl2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_102915191 72.89 ENSRNOT00000017851
lactate dehydrogenase C
chr6_+_54417903 70.63 ENSRNOT00000052356
phosphoribosyl pyrophosphate synthetase 1-like 1
chr5_-_135472116 59.73 ENSRNOT00000022170
nuclear autoantigenic sperm protein
chr7_-_26144466 58.52 ENSRNOT00000009162
four and a half LIM domains 4
chr13_-_87847263 58.32 ENSRNOT00000003650
NUF2, NDC80 kinetochore complex component
chr15_-_44411004 55.09 ENSRNOT00000031163
cell division cycle associated 2
chr2_+_78825074 54.05 ENSRNOT00000032027
membrane associated ring-CH-type finger 11
chr3_-_118427851 53.94 ENSRNOT00000055995
family with sequence similarity 227, member B
chr3_+_110367939 49.28 ENSRNOT00000010406
BUB1 mitotic checkpoint serine/threonine kinase B
chr2_+_197682000 46.25 ENSRNOT00000066821
HORMA domain containing 1
chr14_+_85814824 45.15 ENSRNOT00000090046
ENSRNOT00000083756
ankyrin repeat domain 36
chr9_+_88964525 44.94 ENSRNOT00000068236
dynein assembly factor with WD repeats 1
chr10_-_79097807 44.93 ENSRNOT00000003421
kinesin family member 2B
chr17_-_13593423 44.31 ENSRNOT00000019234
CDC28 protein kinase regulatory subunit 2
chr8_+_117170620 42.76 ENSRNOT00000075271
hypothetical LOC498675
chr1_+_142087208 42.50 ENSRNOT00000017532
protein regulator of cytokinesis 1
chr1_+_102915655 42.34 ENSRNOT00000090520
ENSRNOT00000082718
ENSRNOT00000079440
ENSRNOT00000083079
ENSRNOT00000088892
ENSRNOT00000092180
lactate dehydrogenase C
chr4_-_101393329 42.06 ENSRNOT00000007636
similar to RIKEN cDNA 4931417E11
chr5_+_153976535 41.87 ENSRNOT00000030881
similar to RIKEN cDNA 1700029M20
chr17_-_56269242 41.83 ENSRNOT00000021901
lysozyme-like 1
chr9_+_64898459 39.93 ENSRNOT00000029526
shugoshin 2
chr5_+_28480023 39.78 ENSRNOT00000075067
ENSRNOT00000093754
uncharacterized LOC100912373
chr19_-_37370429 38.62 ENSRNOT00000022497
potassium channel tetramerization domain containing 19
chr1_+_15834779 37.67 ENSRNOT00000079069
ENSRNOT00000083012
BCL2-associated transcription factor 1
chr7_+_129973480 37.40 ENSRNOT00000050620
ENSRNOT00000042686
Mov10 RISC complex RNA helicase like 1
chr7_-_100382897 37.40 ENSRNOT00000006510
LOC500876
chr1_+_196737627 37.07 ENSRNOT00000066652
hypothetical protein LOC100271845
chr8_+_52829085 36.63 ENSRNOT00000007754
similar to hypothetical protein FLJ20010
chr10_+_111031414 35.42 ENSRNOT00000074372
patched domain containing 3
chr10_+_14828597 35.12 ENSRNOT00000025434
tektin 4
chr9_-_114152716 34.36 ENSRNOT00000044153

chr9_+_24095751 33.60 ENSRNOT00000018177
phosphoglycerate kinase 2
chr6_+_99433550 33.55 ENSRNOT00000079359
ENSRNOT00000008504
heat shock protein family A member 2
chr3_-_119611136 33.32 ENSRNOT00000016157
non-SMC condensin I complex, subunit H
chr13_+_70852023 33.28 ENSRNOT00000003661
SHC binding and spindle associated 1 like
chr5_-_136053210 32.61 ENSRNOT00000025903
kinesin family member 2C
chr3_+_147894558 31.99 ENSRNOT00000055415
hypothetical protein LOC502684
chrX_-_139079336 31.27 ENSRNOT00000047605
ubiquitin specific peptidase 26
chrY_+_914045 30.53 ENSRNOT00000088593
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr1_-_88734223 30.25 ENSRNOT00000065011
WD repeat domain 62-like 1
chr5_-_127273656 29.34 ENSRNOT00000057341
DMRT-like family B with proline-rich C-terminal, 1
chr1_+_72580424 28.80 ENSRNOT00000022977
ubiquitin-conjugating enzyme E2S
chr1_-_261051498 28.77 ENSRNOT00000071417
Rho GTPase activating protein 19
chr14_-_3462629 28.57 ENSRNOT00000061538
bromodomain testis associated
chr11_+_52828116 28.46 ENSRNOT00000035340
coiled-coil domain containing 54
chr17_-_44595323 28.35 ENSRNOT00000086767
POM121 transmembrane nucleoporin-like 2
chr5_-_62153762 28.04 ENSRNOT00000066001
ENSRNOT00000086962
tripartite motif-containing 14
chr3_+_7279340 28.03 ENSRNOT00000017029
adenylate kinase 8
chr9_+_98279022 27.96 ENSRNOT00000038536
RNA binding motif protein 44
chr14_-_81339526 26.61 ENSRNOT00000015894
G protein-coupled receptor kinase 4
chr19_-_869490 26.51 ENSRNOT00000080433
CKLF-like MARVEL transmembrane domain containing 1
chr10_-_47630799 25.95 ENSRNOT00000057907
solute carrier family 47 member 2
chr10_-_58924137 25.27 ENSRNOT00000066740
tektin 1
chr11_-_32469566 24.99 ENSRNOT00000002718
similar to RIKEN cDNA 4930563D23
chrX_+_123023280 24.88 ENSRNOT00000087749
predicted gene 6268
chr1_-_157700064 24.78 ENSRNOT00000031974
DNA damage-induced apoptosis suppressor
chr8_-_40078165 24.64 ENSRNOT00000014866
sperm autoantigenic protein 17
chr15_-_29446332 24.62 ENSRNOT00000082901

chr16_-_75581325 24.34 ENSRNOT00000058031
defensin beta 33
chr9_-_46475040 24.31 ENSRNOT00000078196
RFX family member 8, lacking RFX DNA binding domain
chr1_-_213534641 24.26 ENSRNOT00000033074
synaptonemal complex central element protein 1
chr2_+_127538659 24.21 ENSRNOT00000093483
ENSRNOT00000058476
solute carrier family 25 member 31
chr14_+_85351358 24.14 ENSRNOT00000031914
rhomboid domain containing 3
chr8_+_128577080 24.07 ENSRNOT00000024172
WD repeat domain 48
chr3_+_170994038 24.00 ENSRNOT00000081823
SPO11, initiator of meiotic double stranded breaks
chr20_+_46044892 23.95 ENSRNOT00000057187
adenylate kinase 9
chr10_+_94466523 23.53 ENSRNOT00000014867
testicular cell adhesion molecule 1
chr9_-_63291350 23.51 ENSRNOT00000058831
heat shock transcription factor, Y linked 2
chr20_-_28814636 23.41 ENSRNOT00000086030
septin 10
chr5_+_118574801 23.18 ENSRNOT00000035949
ubiquitin-conjugating enzyme E2U (putative)
chr13_+_109669680 23.17 ENSRNOT00000068623
NSL1, MIS12 kinetochore complex component
chr17_-_14373983 23.04 ENSRNOT00000071112

chr5_+_151413382 23.00 ENSRNOT00000012626
CD164 molecule like 2
chr10_-_91291774 22.93 ENSRNOT00000004356
rCG33642-like
chr10_-_56530842 22.87 ENSRNOT00000077451

chr5_+_117586103 22.49 ENSRNOT00000084640
ubiquitin specific peptidase 1
chr18_-_40452456 21.79 ENSRNOT00000004747
motile sperm domain containing 4
chr10_-_75202030 21.78 ENSRNOT00000050349
olfactory receptor 1522
chr4_-_176596591 21.54 ENSRNOT00000086365
RecQ like helicase
chr12_+_38490230 21.32 ENSRNOT00000047861
diablo, IAP-binding mitochondrial protein
chr5_+_152680407 21.21 ENSRNOT00000076864
stathmin 1
chr4_-_155631856 21.19 ENSRNOT00000088270
solute carrier family 2 member 3
chr1_+_170481468 20.84 ENSRNOT00000081667
dynein heavy chain domain 1
chr13_-_108178609 20.65 ENSRNOT00000004525
centromere protein F
chr2_+_202200797 20.54 ENSRNOT00000042263
ENSRNOT00000071938
sperm associated antigen 17
chr6_-_26855658 20.51 ENSRNOT00000011635
ATP/GTP binding protein-like 5
chr10_+_49368314 20.27 ENSRNOT00000004392
CMT1A duplicated region transcript 4
chr1_-_162713610 20.24 ENSRNOT00000018091
aquaporin 11
chr4_-_179904844 20.02 ENSRNOT00000085386
lamin tail domain containing 1
chr7_-_129919946 20.02 ENSRNOT00000079976

chr8_-_59239954 20.00 ENSRNOT00000016104
acyl-CoA synthetase bubblegum family member 1
chr17_-_89780691 19.64 ENSRNOT00000091830
ankyrin repeat domain-containing protein 7-like
chr20_+_12429315 19.34 ENSRNOT00000001675
poly(rC) binding protein 3
chr10_-_10808585 19.11 ENSRNOT00000036954
similar to hypothetical protein
chr7_+_123296183 18.94 ENSRNOT00000048614
hypothetical protein LOC100362109
chr16_-_7336335 18.58 ENSRNOT00000044991
PHD finger protein 7
chrX_+_144994139 18.37 ENSRNOT00000071783
pre-mRNA-splicing factor CWC22 homolog
chr11_+_42945084 18.32 ENSRNOT00000002292
crystallin beta-gamma domain containing 3
chr5_+_108278217 18.18 ENSRNOT00000038972
DMRT-like family A1
chr17_-_89683480 17.85 ENSRNOT00000052342
POTE ankyrin domain family, member C
chr17_+_15194262 17.84 ENSRNOT00000073070

chr9_+_18489284 17.78 ENSRNOT00000027299
ZNRD1 antisense RNA 1
chr10_+_102199837 17.77 ENSRNOT00000037371
hypothetical LOC287798
chr7_+_61174369 17.51 ENSRNOT00000048765
ENSRNOT00000091885
Mdm1 nuclear protein
chr14_+_16924960 17.45 ENSRNOT00000003009
coiled-coil domain containing 158
chr7_+_116653664 17.23 ENSRNOT00000076606
zinc finger protein 41
chr20_+_4967194 16.99 ENSRNOT00000070846
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr5_-_62187930 16.81 ENSRNOT00000011787
coronin 2A
chr2_-_122756842 16.28 ENSRNOT00000080181
coiled-coil domain containing 144B
chr17_-_44758170 16.17 ENSRNOT00000091176
histone cluster 1 H2B family member o
chr20_-_3419831 15.94 ENSRNOT00000046798
mediator of DNA damage checkpoint 1
chr8_+_107499262 15.74 ENSRNOT00000081029
centrosomal protein 70
chr1_-_16687817 15.73 ENSRNOT00000091376
ENSRNOT00000081620
MYB proto-oncogene, transcription factor
chr13_-_110257367 15.69 ENSRNOT00000005576
denticleless E3 ubiquitin protein ligase homolog
chr14_+_97686121 15.68 ENSRNOT00000074877
POM121 transmembrane nucleoporin-like 12
chr20_-_46666830 15.59 ENSRNOT00000000331
centrosomal protein 57-like 1
chr8_+_128577345 15.45 ENSRNOT00000082356
WD repeat domain 48
chr7_+_126736732 15.00 ENSRNOT00000022012
G-2 and S-phase expressed 1
chr6_+_129835919 14.96 ENSRNOT00000036035
vaccinia related kinase 1
chr17_+_44556039 14.93 ENSRNOT00000086540
protease, serine 16
chr18_-_13183263 14.72 ENSRNOT00000050933
coiled-coil domain containing 178
chr19_-_37819789 14.71 ENSRNOT00000036702
centromere protein T
chr7_+_125937928 14.70 ENSRNOT00000044274
family with sequence similarity 118, member A
chr9_-_82477136 14.68 ENSRNOT00000026753
ENSRNOT00000089555
regulated endocrine-specific protein 18
chr2_-_140334912 14.58 ENSRNOT00000015067
E74-like factor 2
chr1_+_248195797 14.41 ENSRNOT00000066891
tumor protein D55-like
chr19_+_24747178 14.21 ENSRNOT00000038879
ENSRNOT00000079106
DnaJ heat shock protein family (Hsp40) member B1
chr2_+_24024791 14.15 ENSRNOT00000089599
ENSRNOT00000066302
adaptor-related protein complex 3, beta 1 subunit
chr10_-_14788617 14.08 ENSRNOT00000043626
calcium voltage-gated channel subunit alpha1 H
chr5_-_134978125 13.93 ENSRNOT00000018004
RAD54 like (S. cerevisiae)
chr16_+_54765325 13.90 ENSRNOT00000065327
ENSRNOT00000086899
myotubularin related protein 7
chrX_-_70946565 13.83 ENSRNOT00000076819
testis expressed 11
chr15_+_34431357 13.72 ENSRNOT00000027604
NOP9 nucleolar protein
chr7_-_94774569 13.63 ENSRNOT00000036399
DNA replication and sister chromatid cohesion 1
chrX_-_135761025 13.59 ENSRNOT00000033044
similar to fibrous sheath interacting protein 2
chr4_-_77347011 13.55 ENSRNOT00000008149
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr6_+_10642700 13.53 ENSRNOT00000040329
karyopherin alpha 2-like
chrX_+_20316893 13.27 ENSRNOT00000082177
WNK lysine deficient protein kinase 3
chr7_+_110031696 13.09 ENSRNOT00000012753
KH RNA binding domain containing, signal transduction associated 3
chr18_-_27289876 13.08 ENSRNOT00000027663
family with sequence similarity 13, member B
chr14_-_33677031 12.94 ENSRNOT00000002908
hypothetical LOC289568
chr14_-_84662143 12.94 ENSRNOT00000057529
ENSRNOT00000080078
HORMA domain containing 2
chr3_-_14538241 12.89 ENSRNOT00000025904
stomatin
chr1_-_66212418 12.88 ENSRNOT00000026074
hypothetical protein LOC691722
chr1_-_90057923 12.86 ENSRNOT00000028674
programmed cell death 2-like
chr5_-_101588001 12.85 ENSRNOT00000016130
PC4 and SFRS1 interacting protein 1
chr5_+_152681101 12.80 ENSRNOT00000076052
ENSRNOT00000022574
stathmin 1
chr15_+_31642169 12.72 ENSRNOT00000072362

chr2_-_165600748 12.71 ENSRNOT00000013216
intraflagellar transport 80
chr3_-_20518105 12.49 ENSRNOT00000050435

chr19_-_37281933 12.49 ENSRNOT00000059663
leucine rich repeat containing 29
chr6_+_37144787 12.48 ENSRNOT00000075503
RAD51 associated protein 2
chr10_+_55138633 12.44 ENSRNOT00000057223
major facilitator superfamily domain containing 6-like
chr3_+_119994537 12.38 ENSRNOT00000018677
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr4_+_5841998 12.02 ENSRNOT00000010025
X-ray repair cross complementing 2
chr9_+_60039297 11.88 ENSRNOT00000016262
solute carrier family 39 member 10
chr7_-_23843505 11.86 ENSRNOT00000006366
ENSRNOT00000077577
F-box protein 7
chr6_-_135049728 11.74 ENSRNOT00000009556
heat shock protein 90 alpha family class A member 1
chr14_+_38247791 11.68 ENSRNOT00000064128
corin, serine peptidase
chr2_-_219693629 11.58 ENSRNOT00000020907
major facilitator superfamily domain containing 14A
chr7_-_27136652 11.36 ENSRNOT00000086905
host cell factor C2
chr4_-_51003117 11.33 ENSRNOT00000034936
taste receptor, type 2, member 118
chr8_-_36467627 11.32 ENSRNOT00000082346
family with sequence similarity 118, member B
chrX_-_136807885 11.28 ENSRNOT00000010325
immunoglobulin superfamily, member 1
chr8_+_116311078 11.25 ENSRNOT00000037363
Ras association domain family member 1
chr16_-_20939545 11.24 ENSRNOT00000027457
SURP and G patch domain containing 2
chr19_+_37795658 11.11 ENSRNOT00000025686
translin-associated factor X interacting protein 1
chr6_-_50923510 11.11 ENSRNOT00000010631
B-cell receptor-associated protein 29
chr8_+_116302513 11.10 ENSRNOT00000039258
zinc finger, MYND-type containing 10
chr1_+_126961644 11.06 ENSRNOT00000045742
small nuclear ribonucleoprotein polypeptide A'
chr8_+_117906014 10.96 ENSRNOT00000056180
serine peptidase inhibitor, Kazal type 8
chr7_+_37812831 10.83 ENSRNOT00000005910
BTG anti-proliferation factor 1
chr3_+_119776925 10.69 ENSRNOT00000018549
dual specificity phosphatase 2
chr1_+_214182830 10.60 ENSRNOT00000022867
leucine rich repeat containing 56
chr6_-_76079283 10.60 ENSRNOT00000082198
protein phosphatase 2, regulatory subunit B'', gamma
chr1_-_80178708 10.45 ENSRNOT00000088676
vasodilator-stimulated phosphoprotein
chr7_-_83348487 10.45 ENSRNOT00000006685
NudC domain containing 1
chr10_-_31493419 10.34 ENSRNOT00000009211
IL2-inducible T-cell kinase
chr8_+_22402890 10.33 ENSRNOT00000079230
interleukin enhancer binding factor 3
chr3_+_114900343 10.33 ENSRNOT00000068129
sulfide quinone reductase-like (yeast)
chr13_-_95348913 10.21 ENSRNOT00000057879
AKT serine/threonine kinase 3
chr3_-_117389456 10.18 ENSRNOT00000007103
ENSRNOT00000081533
myelin expression factor 2
chr10_-_109913879 10.15 ENSRNOT00000072947
similar to Lung carbonyl reductase [NADPH] (NADPH-dependent carbonyl reductase) (LCR) (Adipocyte P27 protein) (AP27)
chr2_-_181874223 10.13 ENSRNOT00000035846
RNA binding motif protein 46
chr2_-_198120041 10.10 ENSRNOT00000079621
ENSRNOT00000028747
pleckstrin homology domain containing O1
chrX_+_72685300 10.03 ENSRNOT00000076215
DMRT-like family C1c1
chr7_+_12022285 9.94 ENSRNOT00000024080
RNA exonuclease 1 homolog
chr8_+_117280705 9.74 ENSRNOT00000085038
ubiquitin specific peptidase 19
chr2_-_222935973 9.72 ENSRNOT00000071934

chr3_+_7884822 9.64 ENSRNOT00000019157
mediator complex subunit 27
chr3_+_100366168 9.51 ENSRNOT00000006689
kinesin family member 18A
chr12_-_24578761 9.49 ENSRNOT00000076209
transducin (beta)-like 2
chr10_-_104163634 9.45 ENSRNOT00000005198
MIF4G domain containing
chr20_-_34683506 9.41 ENSRNOT00000063920
centrosomal protein 85-like
chr6_+_109043880 9.37 ENSRNOT00000008730
eukaryotic translation initiation factor 2B subunit beta
chr11_-_27971359 9.34 ENSRNOT00000085629
ENSRNOT00000051060
ENSRNOT00000042581
ENSRNOT00000050073
ENSRNOT00000081066
glutamate ionotropic receptor kainate type subunit 1
chr14_+_83889089 9.31 ENSRNOT00000078980
MORC family CW-type zinc finger 2
chr2_+_157453428 9.30 ENSRNOT00000051494
leucine, glutamate and lysine rich 1
chr3_-_21684132 9.19 ENSRNOT00000012364
zinc finger and BTB domain containing 6
chr4_-_183417667 9.14 ENSRNOT00000089160
family with sequence similarity 60, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of Mybl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
38.4 115.2 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
17.8 89.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
11.8 59.2 GO:0051177 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
9.5 28.6 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
9.0 36.2 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
8.5 34.0 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
8.3 33.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
8.0 23.9 GO:0009216 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) dGDP metabolic process(GO:0046066)
7.9 39.5 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
7.2 28.8 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) protein K29-linked ubiquitination(GO:0035519)
7.0 35.1 GO:0080154 regulation of fertilization(GO:0080154)
6.0 30.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
5.4 32.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
5.2 15.7 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
5.1 20.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
4.7 14.2 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
4.4 13.3 GO:2000688 positive regulation of rubidium ion transport(GO:2000682) positive regulation of rubidium ion transmembrane transporter activity(GO:2000688)
4.0 20.2 GO:0015793 glycerol transport(GO:0015793)
4.0 20.0 GO:0001552 ovarian follicle atresia(GO:0001552)
3.9 19.6 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
3.9 11.7 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
3.7 15.0 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
3.6 17.8 GO:0034486 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
3.4 13.6 GO:0034421 post-translational protein acetylation(GO:0034421)
3.3 60.3 GO:0043486 histone exchange(GO:0043486)
3.3 13.3 GO:0030576 Cajal body organization(GO:0030576)
3.0 35.5 GO:0000733 DNA strand renaturation(GO:0000733)
2.9 49.8 GO:0034587 piRNA metabolic process(GO:0034587)
2.7 21.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
2.5 17.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
2.5 20.0 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
2.5 24.8 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
2.4 12.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
2.3 20.5 GO:0035608 protein deglutamylation(GO:0035608)
2.3 13.5 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834) response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
2.2 8.6 GO:0060214 endocardium formation(GO:0060214)
2.1 21.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
2.1 6.2 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
2.0 6.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
1.9 11.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
1.8 7.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.8 18.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.8 26.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
1.8 14.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
1.7 5.2 GO:0045819 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) regulation of mismatch repair(GO:0032423) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) T-helper 1 cell activation(GO:0035711) positive regulation of glycogen catabolic process(GO:0045819) negative regulation of apoptotic cell clearance(GO:2000426)
1.7 25.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
1.7 5.0 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
1.6 33.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
1.6 12.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.6 48.7 GO:0021591 ventricular system development(GO:0021591)
1.6 4.7 GO:1902962 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
1.6 1.6 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214)
1.5 18.2 GO:0060179 male mating behavior(GO:0060179)
1.5 11.9 GO:1903599 positive regulation of mitophagy(GO:1903599)
1.4 12.9 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
1.4 2.8 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
1.4 6.8 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
1.3 11.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
1.3 10.3 GO:0001865 NK T cell differentiation(GO:0001865)
1.3 9.0 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
1.2 24.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
1.2 14.7 GO:0051382 kinetochore assembly(GO:0051382)
1.2 3.6 GO:0035759 mesangial cell-matrix adhesion(GO:0035759)
1.2 54.3 GO:0051310 metaphase plate congression(GO:0051310)
1.2 4.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.2 3.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.2 44.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.2 3.6 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
1.2 23.6 GO:0072673 lamellipodium morphogenesis(GO:0072673)
1.2 3.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
1.2 3.5 GO:0006713 glucocorticoid catabolic process(GO:0006713)
1.1 10.2 GO:0050957 equilibrioception(GO:0050957)
1.1 15.7 GO:0019985 translesion synthesis(GO:0019985)
1.1 9.0 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
1.1 4.4 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
1.1 10.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.1 3.2 GO:0006059 hexitol metabolic process(GO:0006059)
1.1 19.2 GO:0060046 regulation of acrosome reaction(GO:0060046)
1.1 24.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
1.0 28.0 GO:0032897 negative regulation of viral transcription(GO:0032897)
1.0 55.8 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
1.0 14.4 GO:0036159 inner dynein arm assembly(GO:0036159)
1.0 5.1 GO:0030070 insulin processing(GO:0030070)
1.0 13.9 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
1.0 18.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
1.0 4.8 GO:2000790 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.9 9.3 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.8 22.5 GO:0006282 regulation of DNA repair(GO:0006282)
0.8 24.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.8 5.7 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.8 2.4 GO:2000409 regulation of T cell extravasation(GO:2000407) positive regulation of T cell extravasation(GO:2000409)
0.8 4.0 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.8 3.9 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.7 5.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.7 2.2 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.7 5.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.7 4.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.7 2.8 GO:0006014 D-ribose metabolic process(GO:0006014)
0.7 4.0 GO:0006528 asparagine metabolic process(GO:0006528)
0.7 6.6 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.7 2.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.6 4.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.6 6.6 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.6 8.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.6 1.8 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.6 4.6 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.6 1.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.6 9.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.6 2.2 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.5 4.9 GO:0007220 Notch receptor processing(GO:0007220)
0.5 1.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.5 33.6 GO:0030317 sperm motility(GO:0030317)
0.5 21.1 GO:0016574 histone ubiquitination(GO:0016574)
0.5 10.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.5 3.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 6.3 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.5 7.0 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.5 6.0 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.5 5.5 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.4 6.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.4 2.2 GO:0031053 primary miRNA processing(GO:0031053)
0.4 5.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.4 2.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.4 11.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.4 25.2 GO:0006405 RNA export from nucleus(GO:0006405)
0.4 4.1 GO:0033127 regulation of histone phosphorylation(GO:0033127)
0.4 36.9 GO:0009156 ribonucleoside monophosphate biosynthetic process(GO:0009156)
0.4 5.6 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 40.7 GO:0006413 translational initiation(GO:0006413)
0.4 24.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.4 29.7 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.4 32.6 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.4 5.9 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.4 37.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.4 1.8 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.3 5.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.3 1.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 9.4 GO:0006855 drug transmembrane transport(GO:0006855)
0.3 2.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 2.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.3 15.7 GO:0046834 lipid phosphorylation(GO:0046834)
0.3 2.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 4.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.3 2.4 GO:1902414 protein localization to cell junction(GO:1902414)
0.3 2.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.2 8.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 1.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 2.4 GO:0006020 inositol metabolic process(GO:0006020)
0.2 3.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 7.7 GO:0051225 spindle assembly(GO:0051225)
0.2 3.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 24.6 GO:2001252 positive regulation of chromosome organization(GO:2001252)
0.2 4.7 GO:0001502 cartilage condensation(GO:0001502)
0.2 5.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 7.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 2.5 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.2 1.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 7.6 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.2 16.2 GO:0006334 nucleosome assembly(GO:0006334)
0.2 0.7 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.2 7.7 GO:0070972 protein localization to endoplasmic reticulum(GO:0070972)
0.2 3.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.2 3.2 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.2 1.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 13.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 22.9 GO:0007018 microtubule-based movement(GO:0007018)
0.1 4.5 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
0.1 0.9 GO:0061450 trophoblast cell migration(GO:0061450)
0.1 0.6 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 9.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 41.8 GO:0051301 cell division(GO:0051301)
0.1 9.8 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.1 1.0 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.1 1.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 6.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.8 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.8 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 3.8 GO:0006611 protein export from nucleus(GO:0006611)
0.1 17.6 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511)
0.1 0.3 GO:1903551 extracellular exosome assembly(GO:0071971) regulation of extracellular exosome assembly(GO:1903551)
0.1 29.6 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.1 2.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 41.8 GO:0016567 protein ubiquitination(GO:0016567)
0.1 3.5 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.1 2.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 5.1 GO:0006479 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 6.0 GO:0006281 DNA repair(GO:0006281)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 5.2 GO:0042742 defense response to bacterium(GO:0042742)
0.0 1.5 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.7 58.3 GO:0031262 Ndc80 complex(GO:0031262)
5.8 69.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
5.8 23.2 GO:0033503 HULC complex(GO:0033503)
5.8 23.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
4.8 33.6 GO:0036128 CatSper complex(GO:0036128)
4.4 44.0 GO:0044613 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
4.2 33.3 GO:0000796 condensin complex(GO:0000796)
4.2 37.4 GO:0071546 pi-body(GO:0071546)
4.1 20.5 GO:1990716 axonemal central apparatus(GO:1990716)
4.0 11.9 GO:1990037 Lewy body core(GO:1990037)
3.8 30.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
3.6 17.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
3.6 14.2 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
3.4 58.2 GO:0035686 sperm fibrous sheath(GO:0035686)
3.4 43.8 GO:0000801 central element(GO:0000801)
3.3 16.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
3.1 15.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
3.0 9.0 GO:0033061 DNA recombinase mediator complex(GO:0033061)
2.8 2.8 GO:0005663 DNA replication factor C complex(GO:0005663)
2.7 70.5 GO:0097225 sperm midpiece(GO:0097225)
2.6 36.9 GO:0008278 cohesin complex(GO:0008278)
2.5 42.5 GO:0070938 contractile ring(GO:0070938)
2.4 14.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
2.4 19.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
2.4 33.3 GO:0072687 meiotic spindle(GO:0072687)
2.3 11.7 GO:0097524 sperm plasma membrane(GO:0097524)
2.3 9.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
2.1 6.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
2.0 59.2 GO:0000795 synaptonemal complex(GO:0000795)
2.0 93.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
1.8 21.3 GO:0035631 CD40 receptor complex(GO:0035631)
1.7 10.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.6 31.2 GO:0005680 anaphase-promoting complex(GO:0005680)
1.5 9.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
1.3 161.4 GO:0031514 motile cilium(GO:0031514)
1.2 9.5 GO:0005828 kinetochore microtubule(GO:0005828)
1.0 9.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.9 44.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.9 2.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.8 12.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.8 4.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.8 5.5 GO:0000322 storage vacuole(GO:0000322)
0.8 3.0 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.7 8.1 GO:0060091 kinocilium(GO:0060091)
0.7 6.6 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.7 14.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.7 7.6 GO:0042555 MCM complex(GO:0042555)
0.7 4.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.7 6.7 GO:0070652 HAUS complex(GO:0070652)
0.7 9.1 GO:0016580 Sin3 complex(GO:0016580)
0.7 16.9 GO:0002080 acrosomal membrane(GO:0002080)
0.6 3.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.6 12.7 GO:0005686 U2 snRNP(GO:0005686)
0.6 24.3 GO:0030286 dynein complex(GO:0030286)
0.6 4.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.6 5.6 GO:0045179 apical cortex(GO:0045179)
0.6 3.3 GO:1990393 3M complex(GO:1990393)
0.5 12.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.5 5.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.5 3.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 1.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 4.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.4 16.0 GO:1904115 axon cytoplasm(GO:1904115)
0.4 11.1 GO:0034451 centriolar satellite(GO:0034451)
0.4 1.1 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.4 34.7 GO:0005814 centriole(GO:0005814)
0.3 3.4 GO:0001939 female pronucleus(GO:0001939)
0.3 2.7 GO:0016272 prefoldin complex(GO:0016272)
0.3 2.9 GO:0000346 transcription export complex(GO:0000346)
0.3 3.2 GO:0034709 methylosome(GO:0034709)
0.3 26.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 8.1 GO:0030904 retromer complex(GO:0030904)
0.3 6.0 GO:0090544 BAF-type complex(GO:0090544)
0.3 2.0 GO:0042382 paraspeckles(GO:0042382)
0.3 13.3 GO:0015030 Cajal body(GO:0015030)
0.3 5.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 2.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3 1.8 GO:0030870 Mre11 complex(GO:0030870)
0.2 16.2 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.2 10.5 GO:0045171 intercellular bridge(GO:0045171)
0.2 11.0 GO:0005643 nuclear pore(GO:0005643)
0.2 10.8 GO:0072686 mitotic spindle(GO:0072686)
0.2 19.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 3.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 26.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.2 20.0 GO:0005882 intermediate filament(GO:0005882)
0.2 5.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 2.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 47.2 GO:0005929 cilium(GO:0005929)
0.1 5.6 GO:0043034 costamere(GO:0043034)
0.1 1.8 GO:0031932 TORC2 complex(GO:0031932)
0.1 72.5 GO:0005694 chromosome(GO:0005694)
0.1 3.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.2 GO:1902555 endoribonuclease complex(GO:1902555)
0.1 1.4 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.6 GO:0016592 mediator complex(GO:0016592)
0.1 13.5 GO:0005874 microtubule(GO:0005874)
0.1 1.8 GO:0030686 90S preribosome(GO:0030686)
0.0 5.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
28.8 115.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
11.2 33.6 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
11.1 44.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
9.4 37.4 GO:0034584 piRNA binding(GO:0034584)
9.3 28.0 GO:0004127 cytidylate kinase activity(GO:0004127)
8.8 70.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
8.0 23.9 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
7.1 21.2 GO:0033222 xylose binding(GO:0033222)
6.0 24.0 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
5.4 21.8 GO:0033149 FFAT motif binding(GO:0033149)
4.6 22.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
3.9 11.7 GO:0032551 UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
3.9 19.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
3.6 21.5 GO:0009378 four-way junction helicase activity(GO:0009378)
3.3 26.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
3.1 15.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
3.0 15.0 GO:0031493 nucleosomal histone binding(GO:0031493)
2.9 38.1 GO:0003796 lysozyme activity(GO:0003796)
2.8 14.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
2.8 33.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
2.7 8.1 GO:1990460 leptin receptor binding(GO:1990460)
2.3 13.9 GO:0036310 annealing helicase activity(GO:0036310)
2.3 18.0 GO:0097100 supercoiled DNA binding(GO:0097100)
2.2 22.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.2 70.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
2.1 12.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
2.0 12.0 GO:0000150 recombinase activity(GO:0000150)
2.0 20.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.9 42.1 GO:0051010 microtubule plus-end binding(GO:0051010)
1.8 7.2 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829)
1.7 37.1 GO:0051861 glycolipid binding(GO:0051861)
1.7 6.6 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
1.6 11.3 GO:0034711 inhibin binding(GO:0034711)
1.6 11.1 GO:0030620 U2 snRNA binding(GO:0030620)
1.6 15.8 GO:0070878 primary miRNA binding(GO:0070878)
1.5 7.7 GO:0001729 ceramide kinase activity(GO:0001729)
1.5 20.5 GO:0015250 water channel activity(GO:0015250)
1.4 4.2 GO:0016882 cyclo-ligase activity(GO:0016882)
1.3 9.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.3 3.9 GO:0031249 denatured protein binding(GO:0031249)
1.3 30.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
1.1 5.6 GO:0097617 annealing activity(GO:0097617)
1.1 5.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
1.1 5.6 GO:0046624 sphingolipid transporter activity(GO:0046624)
1.1 13.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
1.0 4.2 GO:0042610 CD8 receptor binding(GO:0042610)
1.0 9.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
1.0 4.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.9 17.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.9 6.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.9 28.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.9 6.0 GO:0030911 TPR domain binding(GO:0030911)
0.8 50.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.8 42.5 GO:0019894 kinesin binding(GO:0019894)
0.8 20.6 GO:0070840 dynein complex binding(GO:0070840)
0.8 69.3 GO:0003777 microtubule motor activity(GO:0003777)
0.8 20.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.7 10.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.7 5.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.6 3.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.6 14.2 GO:0001671 ATPase activator activity(GO:0001671)
0.6 9.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.6 2.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.5 12.6 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.5 2.2 GO:0030614 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.5 3.7 GO:0003896 DNA primase activity(GO:0003896)
0.5 3.7 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.5 4.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.5 1.6 GO:0097677 STAT family protein binding(GO:0097677)
0.5 3.6 GO:0008432 JUN kinase binding(GO:0008432)
0.5 4.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.5 7.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.4 4.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.4 2.6 GO:0031386 protein tag(GO:0031386)
0.4 74.4 GO:0042393 histone binding(GO:0042393)
0.4 5.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.4 3.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 1.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.4 11.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 10.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 12.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 13.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 11.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 0.9 GO:0038132 neuregulin binding(GO:0038132)
0.3 23.5 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.3 2.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 3.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 4.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 14.5 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.2 2.0 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 10.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 25.0 GO:0005178 integrin binding(GO:0005178)
0.2 3.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 29.7 GO:0017124 SH3 domain binding(GO:0017124)
0.2 42.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.2 7.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 1.7 GO:0042285 xylosyltransferase activity(GO:0042285)
0.2 10.2 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.0 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.7 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 3.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 19.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 5.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 3.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 4.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 2.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 3.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.7 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 12.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 30.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 2.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.8 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 10.8 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 1.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 2.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 7.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 2.5 GO:0032451 demethylase activity(GO:0032451)
0.1 3.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 4.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 73.0 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 57.0 GO:0008270 zinc ion binding(GO:0008270)
0.1 4.0 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 2.6 GO:0005109 frizzled binding(GO:0005109)
0.1 2.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 13.5 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 2.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.0 GO:0000049 tRNA binding(GO:0000049)
0.0 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0004708 MAP kinase kinase activity(GO:0004708)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 34.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.8 65.9 PID AURORA B PATHWAY Aurora B signaling
1.5 82.1 PID PLK1 PATHWAY PLK1 signaling events
1.3 67.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.9 9.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.6 20.9 PID ATM PATHWAY ATM pathway
0.6 27.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.6 20.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.5 7.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5 7.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.4 8.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 5.5 PID AURORA A PATHWAY Aurora A signaling
0.3 13.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 10.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 22.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.3 12.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 10.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.3 2.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 7.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 6.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 2.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 4.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 6.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 3.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.6 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 87.0 REACTOME KINESINS Genes involved in Kinesins
2.5 48.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
2.2 22.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.8 15.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
1.3 10.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.2 21.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.1 12.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.1 16.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.0 49.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
1.0 93.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.9 28.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.8 20.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.7 9.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.7 9.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 6.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.6 10.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.5 3.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.5 3.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.5 5.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 24.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.4 3.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.4 3.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.4 14.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.4 5.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.3 4.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.3 14.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 9.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 4.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3 17.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.3 4.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 61.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.3 3.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 6.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 10.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 5.7 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.2 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 6.8 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 4.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 4.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.8 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 4.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 3.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 3.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.0 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 5.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 6.8 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases