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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Prop1

Z-value: 1.25

Motif logo

Transcription factors associated with Prop1

Gene Symbol Gene ID Gene Info
ENSRNOG00000003671 PROP paired-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prop1rn6_v1_chr10_-_36452378_36452378-0.072.0e-01Click!

Activity profile of Prop1 motif

Sorted Z-values of Prop1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_40086870 53.89 ENSRNOT00000010027
small muscle protein, X-linked
chr5_-_119564846 48.08 ENSRNOT00000012977
cytochrome P450, family 2, subfamily j, polypeptide 4
chrX_-_142164220 39.06 ENSRNOT00000064780
fibroblast growth factor 13
chr11_+_7265828 36.57 ENSRNOT00000084765
1,4-alpha-glucan branching enzyme 1
chr1_+_248428099 32.11 ENSRNOT00000050984
mannose binding lectin 2
chr2_-_227207584 31.89 ENSRNOT00000065361
ENSRNOT00000080215
myozenin 2
chr9_+_37727942 30.68 ENSRNOT00000016511
ENSRNOT00000074276
myotilin-like
chr8_+_84945444 30.51 ENSRNOT00000008244
kelch-like family member 31
chr18_+_35574002 30.00 ENSRNOT00000093442
ENSRNOT00000070817
ENSRNOT00000093356
myotilin
chr9_+_95501778 29.91 ENSRNOT00000086805
secreted phosphoprotein 2
chr17_-_43504604 29.64 ENSRNOT00000083829
ENSRNOT00000066313
solute carrier family 17 member 1
chr14_+_22142364 28.26 ENSRNOT00000002699
sulfotransferase family 1B member 1
chrM_+_10160 27.54 ENSRNOT00000042928
mitochondrially encoded NADH dehydrogenase 4
chr2_+_22950018 27.15 ENSRNOT00000071804
homer scaffolding protein 1
chr13_+_106463368 26.74 ENSRNOT00000003489
estrogen-related receptor gamma
chr6_+_8284878 26.53 ENSRNOT00000009581
solute carrier family 3 member 1
chr16_-_81797815 26.39 ENSRNOT00000026666
protein Z, vitamin K-dependent plasma glycoprotein
chr10_-_98294522 26.33 ENSRNOT00000005489
ATP binding cassette subfamily A member 8
chr17_-_69862110 25.40 ENSRNOT00000058312
aldo-keto reductase family 1, member C-like
chr3_-_52510507 24.70 ENSRNOT00000091259
sodium voltage-gated channel alpha subunit 1
chr17_-_43543172 24.57 ENSRNOT00000080684
ENSRNOT00000029626
ENSRNOT00000082719
solute carrier family 17 member 3
chr13_-_56693968 24.48 ENSRNOT00000060160

chr2_-_231648122 24.43 ENSRNOT00000014962
ankyrin 2
chrM_+_9451 24.08 ENSRNOT00000041241
mitochondrially encoded NADH dehydrogenase 3
chr2_-_257038105 24.05 ENSRNOT00000071195
prostaglandin F receptor
chr18_+_16146447 24.01 ENSRNOT00000022117
polypeptide N-acetylgalactosaminyltransferase 1
chr10_-_103848035 23.85 ENSRNOT00000029001
fatty acid desaturase 6
chr16_+_54164431 23.78 ENSRNOT00000090763
fibrinogen-like 1
chrM_+_9870 23.65 ENSRNOT00000044582
mitochondrially encoded NADH 4L dehydrogenase
chr7_+_117409576 23.17 ENSRNOT00000017067
cytochrome c-1
chr2_-_28799266 23.11 ENSRNOT00000089293
transmembrane protein 171
chr9_-_85617954 21.49 ENSRNOT00000077331
serpin family E member 2
chr16_+_29674793 21.29 ENSRNOT00000059724
annexin A10
chr6_-_7058314 20.65 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr16_+_54291251 20.59 ENSRNOT00000079006
microtubule associated tumor suppressor 1
chr20_+_31339787 20.28 ENSRNOT00000082463
apoptosis inducing factor, mitochondria associated 2
chr2_-_158133861 20.10 ENSRNOT00000090700
ventricular zone expressed PH domain-containing 1
chr16_+_25773602 19.87 ENSRNOT00000047750
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr8_-_49109981 19.80 ENSRNOT00000019933
tetratricopeptide repeat domain 36
chr1_-_167911961 19.76 ENSRNOT00000025097
olfactory receptor 59
chr4_+_51614676 19.53 ENSRNOT00000060494
ankyrin repeat and SOCS box containing 15
chr2_+_22910236 19.15 ENSRNOT00000078266
homer scaffolding protein 1
chr6_-_127534247 19.04 ENSRNOT00000012500
serpin family A member 6
chr10_+_54352270 18.70 ENSRNOT00000036752
dehydrogenase/reductase 7C
chr6_-_105261549 18.56 ENSRNOT00000009122
synaptojanin 2 binding protein
chr2_+_243502073 18.52 ENSRNOT00000015870
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_+_33176778 18.49 ENSRNOT00000046811
ENSRNOT00000007371
apolipoprotein B
chr18_+_32336102 18.41 ENSRNOT00000018577
fibroblast growth factor 1
chr5_+_6373583 18.22 ENSRNOT00000084749

chr20_+_20378861 17.95 ENSRNOT00000091044
ankyrin 3
chr20_-_45053640 17.85 ENSRNOT00000072256
similar to Na+ dependent glucose transporter 1
chr17_-_61332391 17.79 ENSRNOT00000034599
SNRPN upstream reading frame protein-like
chr13_-_82005741 17.71 ENSRNOT00000076404
methyltransferase like 11B
chr14_-_20920286 17.28 ENSRNOT00000004391
solute carrier family 4 member 4
chr6_-_23291568 17.22 ENSRNOT00000085708
CAP-GLY domain containing linker protein family, member 4
chr10_-_98544447 16.92 ENSRNOT00000073149
ATP binding cassette subfamily A member 6
chr15_+_11298478 16.14 ENSRNOT00000007672
leucine rich repeat containing 3B
chr13_-_82006005 16.05 ENSRNOT00000039581
methyltransferase like 11B
chr5_-_88612626 15.67 ENSRNOT00000089560
transducin like enhancer of split 1
chr2_-_117454769 15.56 ENSRNOT00000068381
MDS1 and EVI1 complex locus
chrX_+_118197217 15.54 ENSRNOT00000090922
5-hydroxytryptamine receptor 2C
chr8_-_47094352 15.21 ENSRNOT00000048347
glutamate ionotropic receptor kainate type subunit 4
chr5_+_114516889 15.05 ENSRNOT00000011767
FGGY carbohydrate kinase domain containing
chr1_-_275882444 15.02 ENSRNOT00000083215
glycerol-3-phosphate acyltransferase, mitochondrial
chr18_-_24057917 14.95 ENSRNOT00000023874
Ras-like without CAAX 2
chr10_-_36502313 14.77 ENSRNOT00000041273
similar to Cytochrome c, somatic
chrX_-_64715823 14.76 ENSRNOT00000076297
ankyrin repeat and SOCS box-containing 12
chrX_-_63803915 14.75 ENSRNOT00000076938
MAGE family member D1
chr3_+_134440195 14.65 ENSRNOT00000072928

chr6_+_101532518 14.65 ENSRNOT00000075054
gephyrin
chr8_+_128027958 14.47 ENSRNOT00000045049
acetyl-Coenzyme A acyltransferase 1B
chr2_-_158156444 14.11 ENSRNOT00000088559
ventricular zone expressed PH domain-containing 1
chr8_-_109560747 14.00 ENSRNOT00000087334
protein phosphatase 2, regulatory subunit B'', alpha
chr2_-_158156150 13.13 ENSRNOT00000016621
ventricular zone expressed PH domain-containing 1
chr1_-_255815733 13.10 ENSRNOT00000047387
cytoplasmic polyadenylation element binding protein 3
chr7_+_60099120 13.09 ENSRNOT00000007338
leucine-rich repeat-containing protein 10-like
chr16_-_14382641 12.88 ENSRNOT00000018723
growth hormone inducible transmembrane protein
chr2_+_198965685 12.64 ENSRNOT00000000107
ENSRNOT00000091578
PDZ domain containing 1
chr7_+_59200918 12.53 ENSRNOT00000085073
protein tyrosine phosphatase, receptor type, R
chr18_+_31444472 12.48 ENSRNOT00000075159
ring finger protein 14
chr6_+_56846789 12.43 ENSRNOT00000032108
alkylglycerol monooxygenase
chr7_-_2431197 12.40 ENSRNOT00000003498
hydroxysteroid (17-beta) dehydrogenase 6
chr1_+_215460226 12.38 ENSRNOT00000027270
hypothetical protein LOC685544
chr1_-_104024682 12.37 ENSRNOT00000056081
MAS-related GPR, member X1
chr7_-_52404774 12.23 ENSRNOT00000082100
neuron navigator 3
chr7_+_60087429 12.17 ENSRNOT00000073117
leucine-rich repeat-containing 10
chr5_+_29538380 11.94 ENSRNOT00000010845
calbindin 1
chr11_-_64968437 11.93 ENSRNOT00000059541
COX17 cytochrome c oxidase copper chaperone
chr13_-_104080631 11.76 ENSRNOT00000032865
lysophospholipase-like 1
chr10_-_67479077 11.55 ENSRNOT00000090278
transcription elongation factor, mitochondrial
chr5_+_119727839 11.22 ENSRNOT00000014354
cache domain containing 1
chr11_+_27210593 11.04 ENSRNOT00000084580
MAP3K7 C-terminal like
chr7_+_59326518 10.98 ENSRNOT00000085231
protein tyrosine phosphatase, receptor type, B
chr8_-_109621408 10.61 ENSRNOT00000087398
protein phosphatase 2, regulatory subunit B'', alpha
chrM_+_7006 10.32 ENSRNOT00000043693
mitochondrially encoded cytochrome c oxidase II
chr16_+_78539489 10.18 ENSRNOT00000057897
CUB and Sushi multiple domains 1
chr7_-_68512397 10.14 ENSRNOT00000058036
solute carrier family 16 member 7
chrX_-_37003642 10.14 ENSRNOT00000040770
ENSRNOT00000058834
ENSRNOT00000058833
adhesion G protein-coupled receptor G2
chr6_+_101603319 10.04 ENSRNOT00000030470
gephyrin
chr17_+_16340226 10.03 ENSRNOT00000089140
protein tyrosine phosphatase domain containing 1
chr2_-_35503638 9.87 ENSRNOT00000007560
olfactory receptor 144-like
chr10_-_87335823 9.78 ENSRNOT00000079297
keratin 12
chr14_-_22009300 9.28 ENSRNOT00000088491
ENSRNOT00000087923
casein alpha s1
chr1_-_67134827 9.24 ENSRNOT00000045214
vomeronasal 1 receptor 45
chr2_-_181900856 9.07 ENSRNOT00000082156
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr1_-_217631862 9.03 ENSRNOT00000078514
ENSRNOT00000079805
cortactin
chr10_+_97771264 8.80 ENSRNOT00000005257
arylsulfatase G
chr16_-_81693000 8.62 ENSRNOT00000092353
lysosomal-associated membrane protein 1
chr7_+_49385705 8.60 ENSRNOT00000006083
lin-7 homolog A, crumbs cell polarity complex component
chr1_-_264294630 8.48 ENSRNOT00000035758
SEC31 homolog B, COPII coat complex component
chr7_-_75288365 8.39 ENSRNOT00000036904
ankyrin repeat domain 46
chr5_-_25721072 8.39 ENSRNOT00000021839
transmembrane protein 67
chr1_-_62316450 7.98 ENSRNOT00000079171

chrX_+_82143789 7.88 ENSRNOT00000003724
POU class 3 homeobox 4
chr5_-_128333805 7.77 ENSRNOT00000037523
zinc finger FYVE-type containing 9
chr5_-_134927235 7.74 ENSRNOT00000016751
ubiquinol-cytochrome c reductase hinge protein
chr4_-_55011415 7.56 ENSRNOT00000056996
glutamate metabotropic receptor 8
chr19_+_53629779 7.55 ENSRNOT00000051352
microtubule-associated protein 1 light chain 3 beta
chr7_+_129860114 7.55 ENSRNOT00000085835
Pim-3 proto-oncogene, serine/threonine kinase
chr3_+_77921705 7.55 ENSRNOT00000064006

chr3_+_56056925 7.49 ENSRNOT00000088351
ENSRNOT00000010508
kelch-like family member 23
chr1_-_53802658 7.48 ENSRNOT00000032667
afadin, adherens junction formation factor
chr13_+_47572219 7.44 ENSRNOT00000088449
ENSRNOT00000087664
ENSRNOT00000005853
polymeric immunoglobulin receptor
chr19_+_27404712 7.42 ENSRNOT00000023657
myosin light chain kinase 3
chr16_-_39476384 7.39 ENSRNOT00000092968
glycoprotein m6a
chr13_+_91054974 7.34 ENSRNOT00000091089
C-reactive protein
chr10_+_84966989 7.24 ENSRNOT00000013580
secernin 2
chr16_-_7758189 7.22 ENSRNOT00000026588
2-hydroxyacyl-CoA lyase 1
chr4_-_150522351 7.16 ENSRNOT00000079053
zinc finger protein 9
chr1_+_230268991 7.06 ENSRNOT00000083727
olfactory receptor 363
chr2_+_198303168 6.97 ENSRNOT00000056262
myotubularin related protein 11
chr1_+_172892134 6.97 ENSRNOT00000087918
olfactory receptor 276
chr8_+_106449321 6.97 ENSRNOT00000018622
retinol binding protein 1
chr12_+_38377034 6.97 ENSRNOT00000088002
CAP-GLY domain containing linker protein 1
chr7_+_78188912 6.96 ENSRNOT00000043079
regulating synaptic membrane exocytosis 2
chr7_-_96464049 6.92 ENSRNOT00000006517
hyaluronan synthase 2
chr1_-_66212418 6.84 ENSRNOT00000026074
hypothetical protein LOC691722
chr3_-_134696654 6.83 ENSRNOT00000006454
fibronectin leucine rich transmembrane protein 3
chr8_+_2659865 6.83 ENSRNOT00000088553
ENSRNOT00000010243
caspase 12
chr9_+_66952720 6.74 ENSRNOT00000023678
neurobeachin-like 1
chr2_+_206314213 6.68 ENSRNOT00000056068
BCL2-like 15
chr1_+_172625352 6.68 ENSRNOT00000071859
olfactory receptor 263
chr12_-_54885 6.67 ENSRNOT00000090447

chr7_+_27174882 6.66 ENSRNOT00000051181
glycosyltransferase 8 domain containing 2
chr3_-_154627257 6.61 ENSRNOT00000018328
transglutaminase 2
chr18_+_30398113 6.60 ENSRNOT00000027206
protocadherin beta 5
chr10_+_59894340 6.55 ENSRNOT00000080446
spermatogenesis associated 22
chr14_+_39663421 6.55 ENSRNOT00000003197
gamma-aminobutyric acid type A receptor alpha2 subunit
chr4_+_88232009 6.55 ENSRNOT00000050154
vomeronasal 1 receptor 85
chr8_+_5676665 6.52 ENSRNOT00000012310
matrix metallopeptidase 3
chr1_+_156552328 6.41 ENSRNOT00000055401
discs large MAGUK scaffold protein 2
chr3_+_76179214 6.37 ENSRNOT00000071281
similar to olfactory receptor 1161
chr17_-_24680605 6.33 ENSRNOT00000074869
predicted gene 9979
chr6_+_28382962 6.30 ENSRNOT00000016976
proopiomelanocortin
chr1_-_173764246 6.28 ENSRNOT00000019690
ENSRNOT00000086944
LIM domain only 1
chr3_+_177397892 6.27 ENSRNOT00000078261

chr8_-_20398544 6.27 ENSRNOT00000072834
olfactory receptor 1171
chr1_+_61095171 6.17 ENSRNOT00000042702
vomeronasal 1 receptor 19
chr1_-_755645 5.98 ENSRNOT00000073546
vomeronasal 2 receptor, 6
chrX_+_109996163 5.97 ENSRNOT00000093349
Nik related kinase
chr2_-_199529864 5.94 ENSRNOT00000023742
olfactory receptor 390
chr20_-_3440769 5.93 ENSRNOT00000084981
immediate early response 3
chr2_+_127770676 5.85 ENSRNOT00000068405
abhydrolase domain containing 18
chr9_-_61810417 5.83 ENSRNOT00000020910
raftlin family member 2
chr4_-_113954272 5.82 ENSRNOT00000039966
ENSRNOT00000082996
WW domain-binding protein 1
chr3_+_77152425 5.77 ENSRNOT00000092045
ENSRNOT00000082255
olfactory receptor 653
chr7_+_380741 5.76 ENSRNOT00000091013
nidogen-2-like
chr1_-_67206713 5.75 ENSRNOT00000048195
vomeronasal 1 receptor 43
chrX_+_124894706 5.75 ENSRNOT00000066677
MCTS1, re-initiation and release factor
chr3_-_103090390 5.70 ENSRNOT00000045645
olfactory receptor 777
chr1_-_154165524 5.69 ENSRNOT00000023468
Hikeshi, heat shock protein nuclear import factor
chr8_+_117297670 5.59 ENSRNOT00000082628
glutaminyl-tRNA synthetase
chr1_+_66959610 5.58 ENSRNOT00000072122
ENSRNOT00000045994
vomeronasal 1 receptor 48
chr3_-_103140972 5.58 ENSRNOT00000052368
olfactory receptor 780
chr8_+_43675950 5.58 ENSRNOT00000079430
olfactory receptor 1323
chr5_+_10178302 5.54 ENSRNOT00000009679
syntrophin, gamma 1
chrX_+_92131209 5.51 ENSRNOT00000004462
poly A binding protein, cytoplasmic 5
chr10_-_34301197 5.51 ENSRNOT00000044667
olfactory receptor 1383
chr3_-_77483322 5.51 ENSRNOT00000008077
olfactory receptor 661
chr7_-_145338152 5.48 ENSRNOT00000055268
salivary protein 1
chr20_+_25990304 5.36 ENSRNOT00000033980
leucine rich repeat transmembrane neuronal 3
chr3_-_138683318 5.32 ENSRNOT00000029701
double zinc ribbon and ankyrin repeat domains 1
chr1_+_80982358 5.30 ENSRNOT00000078462

chr6_+_64252970 5.23 ENSRNOT00000093700
patatin-like phospholipase domain containing 8
chr8_+_18785118 5.20 ENSRNOT00000090997
similar to olfactory receptor 829
chrX_+_122313470 5.18 ENSRNOT00000018322
similar to hypothetical protein
chr16_-_83084975 5.12 ENSRNOT00000017947
Rho guanine nucleotide exchange factor 7
chr1_-_67094567 5.12 ENSRNOT00000073583

chr13_+_51126459 5.11 ENSRNOT00000042046
ENSRNOT00000087240
myogenin
chr3_-_36660758 4.99 ENSRNOT00000006111
Rho family GTPase 3
chr7_+_129860327 4.97 ENSRNOT00000043461
Pim-3 proto-oncogene, serine/threonine kinase
chr3_-_78235760 4.95 ENSRNOT00000008435
olfactory receptor 698
chr1_-_67065797 4.91 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr3_+_5709236 4.91 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr8_-_39551700 4.89 ENSRNOT00000091894
ENSRNOT00000076025
PBX/knotted 1 homeobox 2
chrY_+_914045 4.84 ENSRNOT00000088593
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr16_-_47537476 4.77 ENSRNOT00000050279
claudin 24
chr8_-_132911193 4.75 ENSRNOT00000087799
FYVE and coiled-coil domain containing 1
chr18_-_43945273 4.73 ENSRNOT00000088900
DTW domain containing 2
chr13_+_76962504 4.69 ENSRNOT00000076581
ring finger and WD repeat domain 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Prop1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.3 33.8 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
8.2 24.6 GO:0090249 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
8.0 32.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
6.6 19.8 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
6.1 24.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
5.8 23.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
5.6 39.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
5.4 21.5 GO:0061107 seminal vesicle development(GO:0061107)
5.2 15.5 GO:0031583 phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
5.2 20.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
4.9 24.7 GO:0098970 establishment of synaptic specificity at neuromuscular junction(GO:0007529) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
4.8 24.1 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
4.8 24.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
4.5 17.9 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
4.3 46.8 GO:0006068 ethanol catabolic process(GO:0006068)
3.7 18.4 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
3.3 53.3 GO:0043651 linoleic acid metabolic process(GO:0043651)
3.3 13.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
3.2 53.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
3.2 12.6 GO:0015879 carnitine transport(GO:0015879)
3.1 12.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
3.0 11.9 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
3.0 11.9 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
2.9 11.8 GO:0002084 protein depalmitoylation(GO:0002084)
2.9 8.6 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
2.9 54.2 GO:0046415 urate metabolic process(GO:0046415)
2.6 18.5 GO:0006642 triglyceride mobilization(GO:0006642)
2.5 15.0 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
2.5 7.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
2.2 6.6 GO:0018199 peptidyl-glutamine modification(GO:0018199)
2.0 10.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
2.0 16.0 GO:0006776 vitamin A metabolic process(GO:0006776)
1.9 24.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.9 7.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
1.7 6.9 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) positive regulation of hyaluronan biosynthetic process(GO:1900127) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.7 15.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.6 4.9 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
1.6 12.8 GO:0032596 protein transport into membrane raft(GO:0032596)
1.6 6.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
1.5 15.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
1.5 7.5 GO:0034334 adherens junction maintenance(GO:0034334)
1.5 4.5 GO:0006567 threonine catabolic process(GO:0006567)
1.4 8.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.4 4.3 GO:0000958 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962)
1.4 31.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.3 14.8 GO:0007258 JUN phosphorylation(GO:0007258)
1.3 18.6 GO:0032927 negative regulation of activin receptor signaling pathway(GO:0032926) positive regulation of activin receptor signaling pathway(GO:0032927)
1.3 5.1 GO:0014873 regulation of muscle atrophy(GO:0014735) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
1.3 5.0 GO:0002188 translation reinitiation(GO:0002188)
1.2 7.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.2 7.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
1.2 3.5 GO:0006069 ethanol oxidation(GO:0006069)
1.2 16.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
1.2 16.1 GO:0009642 response to light intensity(GO:0009642)
1.1 6.8 GO:0034059 response to anoxia(GO:0034059)
1.1 23.8 GO:0035634 response to stilbenoid(GO:0035634)
1.1 9.0 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
1.1 9.8 GO:0061303 cornea development in camera-type eye(GO:0061303)
1.1 6.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.1 4.3 GO:1903015 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
1.0 12.4 GO:0046485 ether lipid metabolic process(GO:0046485)
1.0 41.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
1.0 6.0 GO:0060721 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
1.0 12.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.9 6.6 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.9 6.3 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.9 11.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.9 2.6 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.9 16.3 GO:2000811 negative regulation of anoikis(GO:2000811)
0.9 18.7 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.8 4.7 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.8 8.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826) photoreceptor cell outer segment organization(GO:0035845) negative regulation of centrosome cycle(GO:0046606)
0.8 6.8 GO:0003344 pericardium morphogenesis(GO:0003344)
0.7 36.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.7 20.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.7 4.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.7 26.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.6 6.4 GO:0046710 GDP metabolic process(GO:0046710)
0.6 5.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.6 7.6 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.6 4.3 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.6 26.4 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.6 4.6 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.6 7.8 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.6 2.8 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 1.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.5 17.3 GO:0015701 bicarbonate transport(GO:0015701)
0.5 5.9 GO:0045820 negative regulation of glycolytic process(GO:0045820)
0.5 7.0 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.5 31.9 GO:0030239 myofibril assembly(GO:0030239)
0.5 2.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5 4.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.4 6.7 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.4 4.3 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.4 9.9 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.4 13.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 3.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 1.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.4 12.4 GO:0008209 androgen metabolic process(GO:0008209)
0.4 3.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.4 4.2 GO:0072189 ureter development(GO:0072189)
0.4 1.1 GO:0006059 hexitol metabolic process(GO:0006059) inner medullary collecting duct development(GO:0072061)
0.4 1.1 GO:0042245 RNA repair(GO:0042245)
0.4 2.2 GO:0097264 self proteolysis(GO:0097264)
0.4 1.8 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.3 1.4 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.3 3.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3 48.7 GO:0006941 striated muscle contraction(GO:0006941)
0.3 2.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 1.3 GO:0030242 pexophagy(GO:0030242)
0.3 29.9 GO:0046849 bone remodeling(GO:0046849)
0.3 7.9 GO:0090103 cochlea morphogenesis(GO:0090103)
0.3 45.9 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.3 2.5 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.3 12.2 GO:0055013 cardiac muscle cell development(GO:0055013)
0.2 4.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.2 1.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 20.3 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.2 7.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 1.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 2.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 276.8 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.2 0.9 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.2 19.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 24.5 GO:0006865 amino acid transport(GO:0006865)
0.2 1.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.1 4.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 7.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 4.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.5 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.1 4.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 4.2 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.3 GO:1905237 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) response to cyclosporin A(GO:1905237) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
0.1 3.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 3.8 GO:0033574 response to testosterone(GO:0033574)
0.1 2.4 GO:0042073 intraciliary transport(GO:0042073)
0.1 4.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 3.2 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 1.7 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 1.0 GO:0007602 phototransduction(GO:0007602)
0.1 2.9 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 1.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 2.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 6.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 8.8 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 1.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.7 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 1.7 GO:0051592 response to calcium ion(GO:0051592)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.8 53.9 GO:0005927 muscle tendon junction(GO:0005927)
6.2 18.7 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
3.1 18.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.8 30.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
2.5 15.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
2.4 21.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
2.2 8.6 GO:0061474 phagolysosome membrane(GO:0061474)
2.1 88.7 GO:0043034 costamere(GO:0043034)
1.5 9.0 GO:0099571 postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
1.5 75.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.4 4.3 GO:0045025 mitochondrial degradosome(GO:0045025)
1.4 6.8 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
1.2 24.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.2 4.9 GO:0034774 secretory granule lumen(GO:0034774)
1.0 39.5 GO:0060077 inhibitory synapse(GO:0060077)
1.0 7.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.9 2.8 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.9 24.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.7 5.1 GO:0000322 storage vacuole(GO:0000322)
0.7 8.6 GO:0044754 autolysosome(GO:0044754)
0.7 7.0 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.7 10.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.7 41.1 GO:0014704 intercalated disc(GO:0014704)
0.7 18.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.6 13.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.5 8.4 GO:0036038 MKS complex(GO:0036038)
0.5 12.6 GO:0031528 microvillus membrane(GO:0031528)
0.5 57.2 GO:0030018 Z disc(GO:0030018)
0.4 32.1 GO:0005581 collagen trimer(GO:0005581)
0.4 5.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4 1.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.4 6.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.4 1.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 21.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.4 24.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.3 1.4 GO:1990005 granular vesicle(GO:1990005)
0.3 4.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 11.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 20.3 GO:0005811 lipid particle(GO:0005811)
0.3 9.1 GO:0005771 multivesicular body(GO:0005771)
0.3 4.2 GO:0030061 mitochondrial crista(GO:0030061)
0.3 2.9 GO:0002177 manchette(GO:0002177)
0.2 19.9 GO:0031966 mitochondrial membrane(GO:0031966)
0.2 7.8 GO:0031901 early endosome membrane(GO:0031901)
0.2 11.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 17.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 74.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 4.2 GO:0005614 interstitial matrix(GO:0005614)
0.2 3.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 14.2 GO:0045095 keratin filament(GO:0045095)
0.2 2.5 GO:0043083 synaptic cleft(GO:0043083)
0.2 9.0 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.5 GO:0000815 ESCRT III complex(GO:0000815)
0.2 8.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 20.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2 7.4 GO:0044295 axonal growth cone(GO:0044295)
0.2 4.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 5.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 7.3 GO:0030120 vesicle coat(GO:0030120)
0.1 5.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 9.8 GO:0030017 sarcomere(GO:0030017)
0.1 2.7 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 10.9 GO:0043195 terminal bouton(GO:0043195)
0.1 22.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 5.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 7.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.9 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 5.7 GO:0032587 ruffle membrane(GO:0032587)
0.1 6.9 GO:0000139 Golgi membrane(GO:0000139)
0.1 376.3 GO:0031224 intrinsic component of membrane(GO:0031224)
0.1 1.6 GO:0016235 aggresome(GO:0016235)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 6.7 GO:0005938 cell cortex(GO:0005938)
0.0 4.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 13.2 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 6.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 3.6 GO:0005635 nuclear envelope(GO:0005635)
0.0 2.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 29.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
16.0 48.1 GO:0008405 arachidonic acid 11,12-epoxygenase activity(GO:0008405)
12.2 36.6 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
11.3 33.8 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
9.3 46.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
6.7 26.7 GO:0050682 AF-2 domain binding(GO:0050682)
6.4 32.1 GO:0005534 galactose binding(GO:0005534)
6.4 31.9 GO:0051373 FATZ binding(GO:0051373)
6.2 24.7 GO:0008940 nitrate reductase activity(GO:0008940)
4.8 14.4 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
4.6 18.6 GO:0070699 type II activin receptor binding(GO:0070699)
4.5 54.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
4.0 28.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
3.8 11.5 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
3.7 18.5 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
3.1 18.5 GO:0035473 lipase binding(GO:0035473)
3.0 11.9 GO:0099510 calcium ion binding involved in regulation of cytosolic calcium ion concentration(GO:0099510)
2.8 75.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
2.5 15.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
2.2 24.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
2.2 15.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
2.1 14.5 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
2.0 10.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
2.0 24.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
1.9 7.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
1.9 7.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.8 12.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
1.8 12.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
1.7 8.6 GO:0097016 L27 domain binding(GO:0097016)
1.7 11.7 GO:0001849 complement component C1q binding(GO:0001849)
1.6 4.9 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
1.6 19.6 GO:0019841 retinol binding(GO:0019841)
1.6 6.3 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
1.5 4.5 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.5 14.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.4 6.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.3 11.9 GO:0016531 copper chaperone activity(GO:0016531)
1.3 6.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
1.3 8.8 GO:0004065 arylsulfatase activity(GO:0004065)
1.2 7.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
1.2 13.1 GO:0035613 RNA stem-loop binding(GO:0035613)
1.2 18.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
1.2 15.0 GO:0030215 semaphorin receptor binding(GO:0030215)
1.1 3.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
1.1 4.3 GO:0045340 mercury ion binding(GO:0045340)
1.1 4.3 GO:0030613 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
1.1 7.5 GO:0030274 LIM domain binding(GO:0030274)
1.0 28.3 GO:0031402 sodium ion binding(GO:0031402)
1.0 18.4 GO:0044548 S100 protein binding(GO:0044548)
1.0 7.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.9 42.6 GO:0030507 spectrin binding(GO:0030507)
0.9 17.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.8 4.2 GO:0070052 collagen V binding(GO:0070052)
0.8 3.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.8 6.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.8 20.6 GO:0019825 oxygen binding(GO:0019825)
0.8 7.9 GO:0003680 AT DNA binding(GO:0003680)
0.7 4.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.7 30.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.7 6.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.7 20.3 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.7 5.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.6 27.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.6 7.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.6 4.3 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.6 9.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.6 33.5 GO:0009055 electron carrier activity(GO:0009055)
0.6 3.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.6 8.4 GO:0051787 misfolded protein binding(GO:0051787)
0.5 3.2 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.5 6.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 4.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.5 7.2 GO:0016805 dipeptidase activity(GO:0016805)
0.5 15.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 3.2 GO:0035375 zymogen binding(GO:0035375)
0.4 1.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.4 11.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.4 40.9 GO:0016503 pheromone receptor activity(GO:0016503)
0.3 7.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 20.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 40.5 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.3 1.1 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.3 19.0 GO:0005496 steroid binding(GO:0005496)
0.3 2.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 31.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 20.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.2 6.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 8.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 4.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 85.9 GO:0005549 odorant binding(GO:0005549)
0.2 4.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 2.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 147.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 1.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 4.9 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.9 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.8 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.9 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 4.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 17.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 7.6 GO:0030674 protein binding, bridging(GO:0030674)
0.1 26.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 5.5 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.7 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 1.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 12.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 4.1 GO:0044325 ion channel binding(GO:0044325)
0.0 2.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.5 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 2.2 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 23.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.4 10.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.4 15.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.4 26.1 PID FGF PATHWAY FGF signaling pathway
0.4 4.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 15.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 25.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.3 3.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.3 40.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 6.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 7.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 7.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 4.3 ST ADRENERGIC Adrenergic Pathway
0.2 5.1 PID AURORA A PATHWAY Aurora A signaling
0.1 11.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 6.0 PID TNF PATHWAY TNF receptor signaling pathway
0.1 16.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 7.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 6.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 4.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 4.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 5.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 17.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 14.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 39.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
3.0 24.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
2.8 22.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
2.6 26.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.3 20.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
2.2 28.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
1.4 18.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
1.2 18.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.1 43.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
1.1 14.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.0 14.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.0 15.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.9 54.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.9 8.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.8 4.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.7 15.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.7 10.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 35.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.6 4.7 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.5 6.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.5 18.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 15.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.5 23.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.4 6.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.4 6.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.4 29.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.4 4.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 20.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.4 7.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.4 7.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.4 10.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.3 7.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 6.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 1.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 13.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 4.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 5.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 12.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 4.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 7.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 3.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 3.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 2.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 16.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 0.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway