Motif ID: AACACUG

Z-value: 1.342


Mature miRNA associated with seed AACACUG:

NamemiRBase Accession
hsa-miR-141 MIMAT0000432
hsa-miR-200a MIMAT0000682



Activity profile for motif AACACUG.

activity profile for motif AACACUG


Sorted Z-values histogram for motif AACACUG

Sorted Z-values for motif AACACUG



Network of associatons between targets according to the STRING database.



First level regulatory network of AACACUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_11903964 3.651 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr19_-_57336373 3.410 NM_001146186
PEG3
paternally expressed 3
chr3_-_116164363 3.244 NM_002338
LSAMP
limbic system-associated membrane protein
chr6_-_94129059 2.900 NM_004440
EPHA7
EPH receptor A7
chr11_+_107461807 2.858 NM_001130037
NM_018712
ELMOD1

ELMO/CED-12 domain containing 1

chr6_+_17281773 2.846 NM_001143942
RBM24
RNA binding motif protein 24
chr1_+_95558072 2.766 NM_001199679
TMEM56
transmembrane protein 56
chr19_+_19322763 2.751 NM_004386
NCAN
neurocan
chr4_-_186697065 2.739 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr6_+_17282931 2.736 NM_153020
RBM24
RNA binding motif protein 24
chr3_-_142682177 2.718 NM_198504
PAQR9
progestin and adipoQ receptor family member IX
chr13_+_80055257 2.688 NM_001161407
NM_019080
NDFIP2

Nedd4 family interacting protein 2

chr13_-_27334777 2.630 NM_005288
GPR12
G protein-coupled receptor 12
chr4_-_186733372 2.413 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr1_+_95582827 2.375 NM_152487
TMEM56
transmembrane protein 56
chr6_+_17282294 2.336 NM_001143941
RBM24
RNA binding motif protein 24
chr6_+_107811272 2.270 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr17_+_56833231 2.269 NM_014906
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr9_-_8733893 2.250 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr4_-_186732047 2.231 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186732208 2.189 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr13_+_96743092 2.183 NM_153456
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr4_-_186578122 2.130 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr14_+_33408458 2.090 NM_001164749
NM_001165893
NM_022123
NM_173159
NPAS3



neuronal PAS domain protein 3



chr18_-_40857245 2.082 NM_020783
SYT4
synaptotagmin IV
chr6_-_84419108 2.058 NM_001242793
NM_001242794
NM_014841
SNAP91


synaptosomal-associated protein, 91kDa homolog (mouse)


chr8_+_91803777 2.052 NM_022351
NECAB1
N-terminal EF-hand calcium binding protein 1
chr6_-_84418705 1.967 NM_001242792
SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr2_-_50574891 1.953 NM_138735
NRXN1
neurexin 1
chr3_+_61547179 1.948 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr6_-_35696359 1.919 NM_001145775
FKBP5
FK506 binding protein 5
chr10_+_112404104 1.887 NM_001134363
RBM20
RNA binding motif protein 20
chr10_+_115803805 1.850 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr18_+_29171729 1.839 NM_000371
TTR
transthyretin
chr19_-_57352055 1.812 NM_001146326
NM_001146327
NM_015363
NM_001146184
NM_001146185
NM_001146187
NM_006210
ZIM2


PEG3



zinc finger, imprinted 2


paternally expressed 3



chr4_-_186877869 1.787 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr2_-_51259536 1.741 NM_001135659
NM_004801
NRXN1

neurexin 1

chr9_-_10612722 1.725 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr17_-_8534008 1.686 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr1_+_169075869 1.683 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr6_-_127840499 1.655 NM_001012279
C6orf174
chromosome 6 open reading frame 174
chr18_+_43304091 1.650 NM_001128588
NM_001146036
NM_015865
SLC14A1


solute carrier family 14 (urea transporter), member 1 (Kidd blood group)


chr6_-_99797530 1.602 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr10_-_103603539 1.586 NM_014591
NM_173191
NM_173192
NM_173193
NM_173195
NM_173197
KCNIP2





Kv channel interacting protein 2





chr11_+_33563772 1.579 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr3_+_158991035 1.504 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr1_+_204913353 1.492 NM_001160331
NFASC
neurofascin
chr10_-_103599596 1.477 NM_173194
KCNIP2
Kv channel interacting protein 2
chr10_+_116853118 1.473 NM_207303
ATRNL1
attractin-like 1
chr1_+_203096835 1.443 NM_000674
NM_001048230
ADORA1

adenosine A1 receptor

chr3_+_159557649 1.414 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr5_+_31799030 1.395 NM_178140
PDZD2
PDZ domain containing 2
chr8_-_12973752 1.393 NM_001164271
DLC1
deleted in liver cancer 1
chr12_+_12938540 1.391 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr9_-_23821477 1.380 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr15_-_77712436 1.376 NM_024776
PEAK1
NKF3 kinase family member
chr6_+_72922513 1.370 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr1_+_218518675 1.359 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr6_-_127780534 1.354 NM_014702
KIAA0408
KIAA0408
chr14_+_53019865 1.333 NM_001099652
GPR137C
G protein-coupled receptor 137C
chr7_-_22396511 1.312 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr9_-_23821842 1.298 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr17_+_36584692 1.294 NM_001199417
ARHGAP23
Rho GTPase activating protein 23
chr1_+_110693131 1.293 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr5_+_173315313 1.289 NM_030627
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr18_+_43306917 1.278 NM_001146037
SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr11_-_12030128 1.265 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr11_-_2170792 1.254 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_-_12030882 1.245 NM_013253
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr7_+_140774031 1.243 NM_001195278
LOC100507421
transmembrane protein 178-like
chr1_+_204797774 1.243 NM_001005388
NM_001005389
NM_001160332
NM_001160333
NM_015090
NFASC




neurofascin




chr11_-_12030622 1.234 NM_015881
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr4_+_144257982 1.231 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr13_-_67804432 1.222 NM_020403
NM_203487
PCDH9

protocadherin 9

chr10_+_88428167 1.221 NM_001171610
LDB3
LIM domain binding 3
chr5_+_126626455 1.215 NM_032446
MEGF10
multiple EGF-like-domains 10
chr11_-_27494232 1.214 NM_018490
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr3_+_39851028 1.188 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr11_-_2162340 1.169 NM_001127598
IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_72427535 1.162 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr7_+_20370724 1.158 NM_002214
ITGB8
integrin, beta 8
chr15_+_51633712 1.149 NM_181789
GLDN
gliomedin
chr18_-_13726582 1.143 NM_001098801
NM_152352
FAM210A

family with sequence similarity 210, member A

chr6_+_138483024 1.142 NM_020340
KIAA1244
KIAA1244
chr6_-_35656677 1.115 NM_001145776
NM_001145777
NM_004117
FKBP5


FK506 binding protein 5


chr1_-_216896640 1.115 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr3_-_24536176 1.106 NM_000461
NM_001128176
NM_001128177
NM_001252634
THRB



thyroid hormone receptor, beta



chr16_+_12995454 1.105 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr2_-_218808705 1.102 NM_022648
TNS1
tensin 1
chr2_+_5832778 1.102 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr17_-_42908178 1.095 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr5_-_41510627 1.086 NM_001005473
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr12_-_42631982 1.079 NM_001190977
YAF2
YY1 associated factor 2
chr22_+_46546498 1.075 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr7_+_94539209 1.074 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr1_+_181452685 1.064 NM_000721
NM_001205293
NM_001205294
CACNA1E


calcium channel, voltage-dependent, R type, alpha 1E subunit


chr4_-_40859081 1.061 NM_001166051
NM_001166052
NM_001166053
NM_001166054
APBB2



amyloid beta (A4) precursor protein-binding, family B, member 2



chr2_-_100939194 1.054 NM_198461
LONRF2
LON peptidase N-terminal domain and ring finger 2
chrX_-_6146655 1.029 NM_181332
NLGN4X
neuroligin 4, X-linked
chr8_-_109095836 1.024 NM_178565
RSPO2
R-spondin 2
chr9_-_91793681 1.022 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr1_-_217262946 1.021 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr11_-_133826879 1.017 NM_014987
IGSF9B
immunoglobulin superfamily, member 9B
chr22_+_38054701 1.012 NM_020315
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr3_-_56502364 0.995 NM_015576
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr16_-_10276610 0.984 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr1_+_40723730 0.983 NM_005857
ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr9_-_6015606 0.979 NM_001243202
NM_001243203
NM_012416
RANBP6


RAN binding protein 6


chr3_+_25469749 0.976 NM_016152
RARB
retinoic acid receptor, beta
chr11_-_17410205 0.974 NM_000525
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr6_+_72926144 0.965 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr17_+_72209500 0.963 NM_032646
TTYH2
tweety homolog 2 (Drosophila)
chr1_+_220701547 0.961 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr12_-_42632150 0.952 NM_001190979
NM_001190980
NM_005748
YAF2


YY1 associated factor 2


chr7_-_75988315 0.950 NM_012479
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr5_+_63802427 0.949 NM_001029875
RGS7BP
regulator of G-protein signaling 7 binding protein
chr17_+_72244504 0.938 NM_052869
TTYH2
tweety homolog 2 (Drosophila)
chr3_+_25469833 0.924 NM_000965
RARB
retinoic acid receptor, beta
chr11_-_2160199 0.916 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr4_+_154074269 0.910 NM_001130067
TRIM2
tripartite motif containing 2
chr1_-_217311095 0.908 NM_001134285
ESRRG
estrogen-related receptor gamma
chr5_-_156772672 0.907 NM_001001343
FNDC9
fibronectin type III domain containing 9
chr1_-_84464728 0.904 NM_024686
TTLL7
tubulin tyrosine ligase-like family, member 7
chr1_-_85358851 0.902 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr2_+_115219153 0.901 NM_001178036
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr16_-_10276115 0.893 NM_001134407
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chrX_-_99665270 0.891 NM_001105243
NM_001184880
NM_020766
PCDH19


protocadherin 19


chr3_-_149375584 0.890 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr3_-_46608039 0.889 NM_024512
LRRC2
leucine rich repeat containing 2
chr12_+_12878718 0.884 NM_001130415
APOLD1
apolipoprotein L domain containing 1
chr9_+_140772228 0.884 NM_000718
NM_001243812
CACNA1B

calcium channel, voltage-dependent, N type, alpha 1B subunit

chr14_-_80677839 0.882 NM_001007023
NM_001242502
NM_001242503
NM_013989
DIO2



deiodinase, iodothyronine, type II



chr11_-_17410863 0.877 NM_001166290
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr1_+_24742244 0.876 NM_020448
NIPAL3
NIPA-like domain containing 3
chr1_+_226736500 0.864 NM_001003665
C1orf95
chromosome 1 open reading frame 95
chr9_-_23826062 0.863 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_-_230513390 0.861 NM_024554
PGBD5
piggyBac transposable element derived 5
chr15_+_80696569 0.859 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr2_+_187464931 0.858 NM_001144999
ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr6_+_72926462 0.856 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr21_+_18885104 0.856 NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338
CXADR




coxsackie virus and adenovirus receptor




chr15_+_77713229 0.849 NM_018200
HMG20A
high mobility group 20A
chr2_+_115919512 0.836 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr17_+_40118696 0.835 NM_033133
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr12_+_110719029 0.833 NM_001681
NM_170665
ATP2A2

ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

chr8_-_82359620 0.827 NM_002677
PMP2
peripheral myelin protein 2
chrX_+_122318095 0.826 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr6_-_53530505 0.826 NM_001003760
KLHL31
kelch-like 31 (Drosophila)
chr19_-_2702738 0.825 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr13_+_42846255 0.822 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr11_-_118047336 0.820 NM_004588
SCN2B
sodium channel, voltage-gated, type II, beta
chrX_-_6145887 0.819 NM_020742
NLGN4X
neuroligin 4, X-linked
chrX_+_109662284 0.818 NM_020769
RGAG1
retrotransposon gag domain containing 1
chr10_+_60936346 0.818 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr4_-_83719896 0.817 NM_001037582
NM_024906
SCD5

stearoyl-CoA desaturase 5

chr9_-_116102533 0.812 NM_001012361
NM_145241
WDR31

WD repeat domain 31

chr1_+_167064086 0.810 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr1_-_230850335 0.806 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr10_+_115312777 0.801 NM_004132
HABP2
hyaluronan binding protein 2
chr1_-_114695061 0.799 NM_205848
SYT6
synaptotagmin VI
chr6_-_30525370 0.794 NM_005275
GNL1
guanine nucleotide binding protein-like 1
chr6_+_73076431 0.791 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr3_+_85008031 0.787 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr1_+_50513685 0.784 NM_001144777
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_+_95066628 0.781 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chr19_+_7911385 0.780 NM_001159944
EVI5L
ecotropic viral integration site 5-like
chr4_+_41362750 0.780 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr10_+_115310589 0.778 NM_001177660
HABP2
hyaluronan binding protein 2
chr7_+_94536926 0.776 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr11_+_105481410 0.775 NM_001112812
GRIA4
glutamate receptor, ionotrophic, AMPA 4
chr4_-_56412968 0.769 NM_004898
CLOCK
clock homolog (mouse)
chr15_+_79575145 0.764 NM_001146341
ANKRD34C
ankyrin repeat domain 34C
chrX_-_72434667 0.762 NM_021963
NAP1L2
nucleosome assembly protein 1-like 2
chr7_+_95401817 0.762 NM_001135556
NM_001135557
NM_004411
DYNC1I1


dynein, cytoplasmic 1, intermediate chain 1


chr14_+_103800492 0.761 NM_001969
EIF5
eukaryotic translation initiation factor 5
chr14_-_35183722 0.752 NM_001243645
NM_138638
CFL2

cofilin 2 (muscle)

chr8_+_85095501 0.749 NM_173848
RALYL
RALY RNA binding protein-like
chr3_+_33318911 0.744 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr12_+_48499655 0.740 NM_001166686
PFKM
phosphofructokinase, muscle
chr12_-_33049664 0.740 NM_001005242
NM_004572
PKP2

plakophilin 2

chr7_-_79082870 0.739 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_+_95679075 0.739 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr22_-_28197469 0.739 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr8_-_75233461 0.734 NM_020647
JPH1
junctophilin 1
chr2_-_37193609 0.734 NM_003162
STRN
striatin, calmodulin binding protein
chr14_+_103801160 0.731 NM_183004
EIF5
eukaryotic translation initiation factor 5
chr3_-_118864881 0.729 NM_152538
IGSF11
immunoglobulin superfamily, member 11
chr9_-_135819995 0.724 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr11_+_7273141 0.724 NM_175733
SYT9
synaptotagmin IX
chrX_+_37865834 0.722 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chr2_+_56411123 0.717 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr4_+_183245136 0.714 NM_001080477
ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr3_+_113465860 0.713 NM_001690
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr15_-_43212911 0.710 NM_173500
TTBK2
tau tubulin kinase 2
chr1_-_220101925 0.709 NM_018713
SLC30A10
solute carrier family 30, member 10
chr13_-_30881141 0.707 NM_001014380
KATNAL1
katanin p60 subunit A-like 1
chr16_+_6069094 0.707 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr10_-_118501981 0.706 NM_025015
HSPA12A
heat shock 70kDa protein 12A
chr2_+_150187028 0.705 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr9_+_4490193 0.705 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
13.72 1.38e-02 GO:0008016 regulation of heart contraction

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
6.23 1.30e-04 GO:0045202 synapse
5.74 8.48e-04 GO:0043005 neuron projection
2.49 2.13e-03 GO:0044459 plasma membrane part
3.50 7.03e-03 GO:0042995 cell projection
1.84 1.54e-02 GO:0005886 plasma membrane
1.81 2.05e-02 GO:0071944 cell periphery

Nothing significant found in function category.