Motif ID: AAGGCAC

Z-value: 2.779


Mature miRNA associated with seed AAGGCAC:

NamemiRBase Accession
hsa-miR-124 MIMAT0000422
hsa-miR-506 MIMAT0002878



Activity profile for motif AAGGCAC.

activity profile for motif AAGGCAC


Sorted Z-values histogram for motif AAGGCAC

Sorted Z-values for motif AAGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGCAC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_116166346 5.971 NM_001172896
NM_001172897
 CAV1

caveolin 1, caveolae protein, 22kDa

chr7_+_116165043 5.691 NM_001172895
 CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_116164838 5.633 NM_001753
 CAV1
caveolin 1, caveolae protein, 22kDa
chr1_+_31885962 5.119 NM_178865
 SERINC2
serine incorporator 2
chr18_+_29078026 4.763 NM_001943
 DSG2
desmoglein 2
chr4_+_124317884 4.724 NM_199327
 SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr4_+_124320664 4.546 NM_005841
 SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr1_+_31886659 4.495 NM_001199039
NM_018565
 SERINC2

serine incorporator 2

chr1_+_182992329 4.465 NM_002293
 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr13_-_110959441 4.456 NM_001845
 COL4A1
collagen, type IV, alpha 1
chr10_-_30024594 4.297 NM_003174
 SVIL
supervillin
chr1_+_31883020 4.261 NM_001199037
 SERINC2
serine incorporator 2
chr12_+_52416615 4.187 NM_001202233
 NR4A1
nuclear receptor subfamily 4, group A, member 1
chr21_-_44846927 4.176 NM_173354
 SIK1
salt-inducible kinase 1
chr3_+_69812620 4.132 NM_001184967
 MITF
microphthalmia-associated transcription factor
chr14_-_61190458 4.069 NM_017420
 SIX4
SIX homeobox 4
chr10_-_29923900 4.028 NM_021738
 SVIL
supervillin
chr1_+_31882411 4.018 NM_001199038
 SERINC2
serine incorporator 2
chr11_+_818836 3.994 NM_020376
 PNPLA2
patatin-like phospholipase domain containing 2
chr1_-_116311398 3.944 NM_001232
 CASQ2
calsequestrin 2 (cardiac muscle)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 80 entries
Enrichment   P-value GO Accession GO Term
6.72 1.05e-02 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
5.13 3.84e-02 GO:0030879 mammary gland development
4.15 5.75e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
3.85 9.34e-10 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.76 9.70e-03 GO:0048732 gland development
3.73 5.62e-03 GO:0001701 in utero embryonic development
3.55 1.22e-05 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
3.47 4.92e-02 GO:0007517 muscle organ development
3.45 1.46e-03 GO:0061061 muscle structure development
3.39 3.62e-02 GO:0043193 positive regulation of gene-specific transcription
3.13 8.57e-04 GO:0043009 chordate embryonic development
3.11 2.22e-07 GO:0045893 positive regulation of transcription, DNA-dependent
3.11 7.51e-03 GO:0032870 cellular response to hormone stimulus
3.10 1.27e-04 GO:0032583 regulation of gene-specific transcription
3.09 1.06e-03 GO:0009792 embryo development ending in birth or egg hatching
3.08 2.54e-02 GO:0007423 sensory organ development
3.06 1.62e-02 GO:0048729 tissue morphogenesis
3.04 6.60e-03 GO:0071495 cellular response to endogenous stimulus
3.01 2.15e-07 GO:0010628 positive regulation of gene expression
2.97 5.45e-07 GO:0051254 positive regulation of RNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
3.33 2.18e-02 GO:0031252 cell leading edge
2.97 2.68e-02 GO:0016323 basolateral plasma membrane
1.55 3.55e-02 GO:0005829 cytosol
1.20 3.25e-02 GO:0005737 cytoplasm
1.14 3.58e-02 GO:0044424 intracellular part
1.13 3.73e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
8.67 1.36e-05 GO:0004879 ligand-dependent nuclear receptor activity
8.34 8.30e-05 GO:0003707 steroid hormone receptor activity
4.58 2.17e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
3.58 2.04e-03 GO:0000975 regulatory region DNA binding
3.58 2.04e-03 GO:0001067 regulatory region nucleic acid binding
3.58 2.04e-03 GO:0044212 transcription regulatory region DNA binding
3.29 1.90e-02 GO:0010843 promoter binding
3.18 3.94e-04 GO:0016563 transcription activator activity
2.98 5.15e-03 GO:0008134 transcription factor binding
2.71 1.94e-02 GO:0003779 actin binding
2.48 2.45e-07 GO:0001071 nucleic acid binding transcription factor activity
2.48 2.45e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
2.45 1.82e-04 GO:0043565 sequence-specific DNA binding
2.40 4.76e-03 GO:0008092 cytoskeletal protein binding
2.28 1.13e-05 GO:0030528 transcription regulator activity
1.38 1.79e-07 GO:0005515 protein binding
1.37 4.04e-02 GO:0046872 metal ion binding
1.19 2.44e-06 GO:0005488 binding