Motif ID: AAGGCAC

Z-value: 2.779


Mature miRNA associated with seed AAGGCAC:

NamemiRBase Accession
hsa-miR-124 MIMAT0000422
hsa-miR-506 MIMAT0002878



Activity profile for motif AAGGCAC.

activity profile for motif AAGGCAC


Sorted Z-values histogram for motif AAGGCAC

Sorted Z-values for motif AAGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_116166346 5.971 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr7_+_116165043 5.691 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_116164838 5.633 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr1_+_31885962 5.119 NM_178865
SERINC2
serine incorporator 2
chr18_+_29078026 4.763 NM_001943
DSG2
desmoglein 2
chr4_+_124317884 4.724 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr4_+_124320664 4.546 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr1_+_31886659 4.495 NM_001199039
NM_018565
SERINC2

serine incorporator 2

chr1_+_182992329 4.465 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr13_-_110959441 4.456 NM_001845
COL4A1
collagen, type IV, alpha 1
chr10_-_30024594 4.297 NM_003174
SVIL
supervillin
chr1_+_31883020 4.261 NM_001199037
SERINC2
serine incorporator 2
chr12_+_52416615 4.187 NM_001202233
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr21_-_44846927 4.176 NM_173354
SIK1
salt-inducible kinase 1
chr3_+_69812620 4.132 NM_001184967
MITF
microphthalmia-associated transcription factor
chr14_-_61190458 4.069 NM_017420
SIX4
SIX homeobox 4
chr10_-_29923900 4.028 NM_021738
SVIL
supervillin
chr1_+_31882411 4.018 NM_001199038
SERINC2
serine incorporator 2
chr11_+_818836 3.994 NM_020376
PNPLA2
patatin-like phospholipase domain containing 2
chr1_-_116311398 3.944 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr10_-_131762017 3.930 NM_001005463
EBF3
early B-cell factor 3
chr11_+_94501503 3.877 NM_130847
AMOTL1
angiomotin like 1
chr6_-_75915566 3.867 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr11_+_12695851 3.783 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_+_69788562 3.763 NM_198159
MITF
microphthalmia-associated transcription factor
chr5_-_158526698 3.728 NM_024007
EBF1
early B-cell factor 1
chr7_-_27183225 3.638 NM_019102
HOXA5
homeobox A5
chr6_+_138725314 3.622 NM_014320
HEBP2
heme binding protein 2
chr3_+_69812961 3.618 NM_006722
MITF
microphthalmia-associated transcription factor
chr16_-_67840464 3.604 NM_020850
RANBP10
RAN binding protein 10
chr3_+_69915374 3.563 NM_198177
MITF
microphthalmia-associated transcription factor
chr11_+_76494132 3.531 NM_015516
TSKU
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr4_+_152330326 3.453 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr1_-_236228476 3.451 NM_002508
NID1
nidogen 1
chr17_-_767287 3.410 NM_001205319
NXN
nucleoredoxin
chr11_-_86666211 3.349 NM_012193
FZD4
frizzled family receptor 4
chr4_-_185747183 3.312 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chrX_+_68048792 3.223 NM_004429
EFNB1
ephrin-B1
chr15_+_41221530 3.211 NM_019074
DLL4
delta-like 4 (Drosophila)
chr17_-_882905 3.211 NM_022463
NXN
nucleoredoxin
chr17_-_41174431 3.187 NM_006373
VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr14_-_21572789 3.185 NM_001102454
ZNF219
zinc finger protein 219
chr6_+_17282931 3.164 NM_153020
RBM24
RNA binding motif protein 24
chr19_-_33793429 3.153 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr9_+_124061880 3.148 NM_000177
GSN
gelsolin
chrX_+_66788682 3.127 NM_001011645
AR
androgen receptor
chr8_-_9008138 3.112 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr12_-_56101667 3.105 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr9_+_124030370 3.102 NM_001127662
NM_001127663
NM_001127664
NM_001127665
NM_001127666
NM_001127667
NM_198252
GSN






gelsolin






chr11_+_832909 3.089 NM_001039490
NM_004357
NM_139029
NM_139030
CD151



CD151 molecule (Raph blood group)



chr14_-_21566728 3.038 NM_016423
ZNF219
zinc finger protein 219
chr10_+_123748688 3.031 NM_206861
NM_206862
TACC2

transforming, acidic coiled-coil containing protein 2

chr9_-_89562103 3.021 NM_002048
GAS1
growth arrest-specific 1
chr6_+_17281773 2.994 NM_001143942
RBM24
RNA binding motif protein 24
chr20_-_10654429 2.990 NM_000214
JAG1
jagged 1
chr9_-_14398981 2.980 NM_001190738
NFIB
nuclear factor I/B
chr6_+_44187241 2.972 NM_001078174
NM_004955
SLC29A1

solute carrier family 29 (nucleoside transporters), member 1

chr10_+_123923104 2.961 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr19_+_54371125 2.961 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr14_-_21567069 2.952 NM_001101672
ZNF219
zinc finger protein 219
chrX_+_66763868 2.939 NM_000044
AR
androgen receptor
chr1_+_53527822 2.916 NM_001199081
PODN
podocan
chr5_+_172068188 2.887 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr17_-_202617 2.887 NM_001190411
NM_001190412
NM_001190413
NM_006987
RPH3AL



rabphilin 3A-like (without C2 domains)



chr6_+_44191276 2.872 NM_001078175
NM_001078176
NM_001078177
SLC29A1


solute carrier family 29 (nucleoside transporters), member 1


chr10_-_113943467 2.859 NM_001244949
NM_020918
GPAM

glycerol-3-phosphate acyltransferase, mitochondrial

chr12_-_56106061 2.856 NM_001144997
ITGA7
integrin, alpha 7
chr1_+_64088886 2.837 NM_001172818
PGM1
phosphoglucomutase 1
chr1_+_61547388 2.829 NM_001145512
NFIA
nuclear factor I/A
chr15_+_91411884 2.768 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr1_-_225840660 2.761 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr20_+_30407175 2.753 NM_033118
MYLK2
myosin light chain kinase 2
chr12_+_53774422 2.751 NM_003109
SP1
Sp1 transcription factor
chr6_+_17282294 2.749 NM_001143941
RBM24
RNA binding motif protein 24
chr8_-_49833823 2.742 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr18_+_77160243 2.734 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr9_-_33167355 2.730 NM_001497
B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr1_+_57110745 2.708 NM_006252
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr4_+_41614911 2.694 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr3_+_187943192 2.684 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_+_36421944 2.675 NM_003149
STAC
SH3 and cysteine rich domain
chrX_+_49028183 2.665 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr3_-_169381417 2.662 NM_001205194
NM_004991
MECOM

MDS1 and EVI1 complex locus

chr8_-_9009050 2.653 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr19_-_50143350 2.640 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr3_-_64673330 2.626 NM_182920
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr12_+_122516555 2.624 NM_014938
MLXIP
MLX interacting protein
chr1_+_64058891 2.610 NM_002633
PGM1
phosphoglucomutase 1
chr2_+_219264477 2.608 NM_021198
NM_182642
CTDSP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

chr16_-_4166185 2.602 NM_001116
ADCY9
adenylate cyclase 9
chr1_+_53527723 2.577 NM_001199080
NM_001199082
NM_153703
PODN


podocan


chr6_+_133562488 2.574 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr9_-_14314036 2.566 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr11_+_111473099 2.560 NM_015191
SIK2
salt-inducible kinase 2
chr8_-_134584012 2.558 NM_003033
NM_173344
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr10_+_89419352 2.550 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr3_-_141747434 2.545 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr22_-_50746000 2.523 NM_012401
PLXNB2
plexin B2
chr12_+_53773924 2.505 NM_001251825
NM_138473
SP1

Sp1 transcription factor

chr12_-_15942350 2.501 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr1_+_64059479 2.500 NM_001172819
PGM1
phosphoglucomutase 1
chr10_+_17270257 2.497 NM_003380
VIM
vimentin
chr2_-_128100673 2.489 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr18_+_42260774 2.483 NM_015559
SETBP1
SET binding protein 1
chr3_-_168864066 2.481 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chrX_-_32430370 2.470 NM_004011
NM_004012
DMD

dystrophin

chr12_-_58240746 2.469 NM_005730
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chrX_-_33357725 2.462 NM_000109
DMD
dystrophin
chr9_+_137218313 2.457 NM_002957
RXRA
retinoid X receptor, alpha
chr17_+_21279667 2.455 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr7_-_42276617 2.455 NM_000168
GLI3
GLI family zinc finger 3
chr4_+_48343502 2.444 NM_020846
SLAIN2
SLAIN motif family, member 2
chr10_+_112404104 2.437 NM_001134363
RBM20
RNA binding motif protein 20
chr2_-_161350304 2.421 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr10_-_14372807 2.419 NM_018027
FRMD4A
FERM domain containing 4A
chr14_-_75422466 2.417 NM_001207012
NM_002632
PGF

placental growth factor

chr12_+_52445185 2.410 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr18_+_19749403 2.386 NM_005257
GATA6
GATA binding protein 6
chr17_+_1959512 2.376 NM_001098202
HIC1
hypermethylated in cancer 1
chr1_+_61547625 2.372 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr17_+_1958354 2.363 NM_006497
HIC1
hypermethylated in cancer 1
chr1_-_214724974 2.356 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_-_33224485 2.350 NM_033668
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr1_+_199996729 2.348 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chrX_-_32173585 2.338 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr9_+_504661 2.332 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr4_+_108910869 2.324 NM_001184705
NM_005327
HADH

hydroxyacyl-CoA dehydrogenase

chr4_+_25657434 2.323 NM_001177998
NM_006424
SLC34A2

solute carrier family 34 (sodium phosphate), member 2

chr11_+_57529233 2.317 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001206883
NM_001206884
NM_001206885
NM_001206886
NM_001206887
NM_001206888
NM_001206889
NM_001206890
NM_001206891
NM_001331
CTNND1





















catenin (cadherin-associated protein), delta 1





















chr14_-_105635114 2.310 NM_002226
NM_145159
JAG2

jagged 2

chr5_+_149997205 2.306 NM_001166209
SYNPO
synaptopodin
chrX_-_31526414 2.300 NM_004014
DMD
dystrophin
chrX_-_33229428 2.293 NM_004006
DMD
dystrophin
chr1_+_61542928 2.292 NM_001145511
NFIA
nuclear factor I/A
chr3_+_69985750 2.291 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr15_-_40401041 2.283 NM_001003940
BMF
Bcl2 modifying factor
chr12_-_118541655 2.281 NM_019086
VSIG10
V-set and immunoglobulin domain containing 10
chr17_-_21156577 2.268 NM_152914
C17orf103
chromosome 17 open reading frame 103
chr4_-_120549827 2.261 NM_001083
PDE5A
phosphodiesterase 5A, cGMP-specific
chr19_-_49496566 2.258 NM_001161587
NM_002103
GYS1

glycogen synthase 1 (muscle)

chr1_+_201979689 2.256 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr9_-_4742042 2.253 NM_001199853
AK3
adenylate kinase 3
chr4_+_25658085 2.249 NM_001177999
SLC34A2
solute carrier family 34 (sodium phosphate), member 2
chr5_+_149980627 2.241 NM_001166208
SYNPO
synaptopodin
chr3_+_187871473 2.235 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr16_-_15950850 2.235 NM_001040113
NM_001040114
NM_002474
NM_022844
MYH11



myosin, heavy chain 11, smooth muscle



chr11_+_46403302 2.235 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr3_-_168864325 2.228 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chr2_+_219263060 2.222 NM_001206878
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr17_+_7123149 2.216 NM_000018
NM_001033859
ACADVL

acyl-CoA dehydrogenase, very long chain

chr5_-_95297597 2.216 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr17_+_57970442 2.207 NM_003161
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr5_-_139422805 2.206 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
NRG2




neuregulin 2




chr6_-_36515245 2.203 NM_007271
STK38
serine/threonine kinase 38
chrX_-_33146543 2.200 NM_004010
NM_004009
DMD

dystrophin

chr3_-_168865521 2.197 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr3_-_120169493 2.194 NM_007085
FSTL1
follistatin-like 1
chr11_+_46403205 2.193 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr6_+_7107986 2.192 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr15_-_40398286 2.176 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chrX_-_10645726 2.170 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr14_-_23652840 2.157 NM_012244
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr5_+_102201526 2.156 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr17_-_42907606 2.152 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr15_-_40398573 2.147 NM_033503
BMF
Bcl2 modifying factor
chr21_+_45875368 2.147 NM_030891
LRRC3
leucine rich repeat containing 3
chr6_+_148663728 2.134 NM_015278
SASH1
SAM and SH3 domain containing 1
chr14_+_24867926 2.126 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr6_+_7107799 2.124 NM_001168344
RREB1
ras responsive element binding protein 1
chr10_-_106093662 2.119 NM_033397
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr12_-_48298765 2.118 NM_000376
NM_001017535
NM_001017536
VDR


vitamin D (1,25- dihydroxyvitamin D3) receptor


chr3_-_187452669 2.116 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr10_-_74856656 2.110 NM_000917
NM_001017962
NM_001142595
NM_001142596
P4HA1



prolyl 4-hydroxylase, alpha polypeptide I



chr7_+_101460881 2.108 NM_181552
CUX1
cut-like homeobox 1
chr3_+_191046873 2.106 NM_174908
NM_178335
CCDC50

coiled-coil domain containing 50

chr9_+_35906188 2.099 NM_001039792
HRCT1
histidine rich carboxyl terminus 1
chr11_+_120081669 2.098 NM_178507
OAF
OAF homolog (Drosophila)
chr2_+_241507928 2.096 NM_018226
RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr4_-_120549115 2.088 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr9_+_133971862 2.085 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr5_-_59189620 2.070 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_+_65672422 2.065 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr3_+_29322802 2.047 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr9_+_22446783 2.046 NM_022160
DMRTA1
DMRT-like family A1
chr8_-_70747200 2.039 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr6_-_52441815 2.022 NM_012288
TRAM2
translocation associated membrane protein 2
chr1_+_2160133 2.015 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chrX_-_71933709 2.011 NM_001122670
NM_001172436
NM_002637
PHKA1


phosphorylase kinase, alpha 1 (muscle)


chr5_-_98262217 2.011 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr19_-_3761621 2.010 NM_004886
APBA3
amyloid beta (A4) precursor protein-binding, family A, member 3
chr2_-_122042767 2.005 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr16_+_69220940 1.997 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr5_-_59064437 1.993 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_154975041 1.989 NM_001252405
NM_015872
ZBTB7B

zinc finger and BTB domain containing 7B

chr14_-_23623493 1.987 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr19_-_40791291 1.985 NM_001243027
NM_001243028
NM_001626
AKT2


v-akt murine thymoma viral oncogene homolog 2


chr9_+_130565141 1.983 NM_004957
FPGS
folylpolyglutamate synthase
chr4_+_41362750 1.982 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr4_+_81952118 1.981 NM_001201
BMP3
bone morphogenetic protein 3
chr14_+_53196852 1.978 NM_001130701
NM_145251
STYX

serine/threonine/tyrosine interacting protein


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.85 9.34e-10 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.81 1.62e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
3.01 2.15e-07 GO:0010628 positive regulation of gene expression
3.11 2.22e-07 GO:0045893 positive regulation of transcription, DNA-dependent
2.85 4.36e-07 GO:0010557 positive regulation of macromolecule biosynthetic process
2.97 5.45e-07 GO:0051254 positive regulation of RNA metabolic process
1.83 5.94e-07 GO:0048518 positive regulation of biological process
2.65 1.96e-06 GO:0031328 positive regulation of cellular biosynthetic process
2.74 2.44e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.60 3.39e-06 GO:0009891 positive regulation of biosynthetic process
2.31 3.53e-06 GO:0031325 positive regulation of cellular metabolic process
1.83 4.96e-06 GO:0048522 positive regulation of cellular process
2.66 6.16e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
2.22 1.11e-05 GO:0009893 positive regulation of metabolic process
1.88 1.12e-05 GO:0048523 negative regulation of cellular process
3.55 1.22e-05 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.60 1.27e-05 GO:0032502 developmental process
2.25 2.28e-05 GO:0010604 positive regulation of macromolecule metabolic process
2.07 2.60e-05 GO:0009653 anatomical structure morphogenesis
1.36 4.86e-05 GO:0050794 regulation of cellular process
1.77 8.51e-05 GO:0048519 negative regulation of biological process
3.10 1.27e-04 GO:0032583 regulation of gene-specific transcription
2.59 1.50e-04 GO:0009790 embryo development
1.31 1.67e-04 GO:0065007 biological regulation
1.58 2.25e-04 GO:0007275 multicellular organismal development
1.67 4.17e-04 GO:0031326 regulation of cellular biosynthetic process
1.69 4.20e-04 GO:0010468 regulation of gene expression
1.74 4.80e-04 GO:0051252 regulation of RNA metabolic process
1.65 6.97e-04 GO:0009889 regulation of biosynthetic process
1.74 7.89e-04 GO:0006355 regulation of transcription, DNA-dependent
3.13 8.57e-04 GO:0043009 chordate embryonic development
1.31 8.61e-04 GO:0050789 regulation of biological process
2.21 8.72e-04 GO:0042127 regulation of cell proliferation
1.69 1.01e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
3.09 1.06e-03 GO:0009792 embryo development ending in birth or egg hatching
1.58 1.12e-03 GO:0048856 anatomical structure development
3.45 1.46e-03 GO:0061061 muscle structure development
1.53 1.47e-03 GO:0080090 regulation of primary metabolic process
1.66 1.61e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.52 1.67e-03 GO:0031323 regulation of cellular metabolic process
1.74 1.89e-03 GO:0030154 cell differentiation
1.54 1.98e-03 GO:0060255 regulation of macromolecule metabolic process
1.72 2.71e-03 GO:0048869 cellular developmental process
1.62 2.85e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.19 4.86e-03 GO:0009888 tissue development
1.18 5.44e-03 GO:0009987 cellular process
3.73 5.62e-03 GO:0001701 in utero embryonic development
4.15 5.75e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.74 6.56e-03 GO:0048513 organ development
3.04 6.60e-03 GO:0071495 cellular response to endogenous stimulus
2.16 7.26e-03 GO:0006351 transcription, DNA-dependent
3.11 7.51e-03 GO:0032870 cellular response to hormone stimulus
3.76 9.70e-03 GO:0048732 gland development
1.57 9.99e-03 GO:0051171 regulation of nitrogen compound metabolic process
6.72 1.05e-02 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
2.49 1.07e-02 GO:0051253 negative regulation of RNA metabolic process
1.56 1.11e-02 GO:0048731 system development
2.28 1.58e-02 GO:0031327 negative regulation of cellular biosynthetic process
3.06 1.62e-02 GO:0048729 tissue morphogenesis
2.46 2.03e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.36 2.24e-02 GO:0009887 organ morphogenesis
2.24 2.43e-02 GO:0009890 negative regulation of biosynthetic process
2.34 2.49e-02 GO:0010629 negative regulation of gene expression
3.08 2.54e-02 GO:0007423 sensory organ development
1.96 2.66e-02 GO:0010941 regulation of cell death
2.63 2.79e-02 GO:0008285 negative regulation of cell proliferation
1.96 3.22e-02 GO:0042981 regulation of apoptosis
3.39 3.62e-02 GO:0043193 positive regulation of gene-specific transcription
2.53 3.71e-02 GO:0048646 anatomical structure formation involved in morphogenesis
2.22 3.73e-02 GO:0045595 regulation of cell differentiation
2.89 3.84e-02 GO:0001501 skeletal system development
1.43 3.84e-02 GO:0023052 signaling
5.13 3.84e-02 GO:0030879 mammary gland development
1.42 3.91e-02 GO:0019222 regulation of metabolic process
1.95 3.95e-02 GO:0043067 regulation of programmed cell death
2.25 4.02e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.24 4.43e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
2.27 4.75e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.47 4.92e-02 GO:0007517 muscle organ development
1.46 4.95e-02 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.33 2.18e-02 GO:0031252 cell leading edge
2.97 2.68e-02 GO:0016323 basolateral plasma membrane
1.20 3.25e-02 GO:0005737 cytoplasm
1.55 3.55e-02 GO:0005829 cytosol
1.14 3.58e-02 GO:0044424 intracellular part
1.13 3.73e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.38 1.79e-07 GO:0005515 protein binding
2.48 2.45e-07 GO:0001071 nucleic acid binding transcription factor activity
2.48 2.45e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.19 2.44e-06 GO:0005488 binding
2.28 1.13e-05 GO:0030528 transcription regulator activity
8.67 1.36e-05 GO:0004879 ligand-dependent nuclear receptor activity
8.34 8.30e-05 GO:0003707 steroid hormone receptor activity
2.45 1.82e-04 GO:0043565 sequence-specific DNA binding
3.18 3.94e-04 GO:0016563 transcription activator activity
3.58 2.04e-03 GO:0000975 regulatory region DNA binding
3.58 2.04e-03 GO:0001067 regulatory region nucleic acid binding
3.58 2.04e-03 GO:0044212 transcription regulatory region DNA binding
2.40 4.76e-03 GO:0008092 cytoskeletal protein binding
2.98 5.15e-03 GO:0008134 transcription factor binding
3.29 1.90e-02 GO:0010843 promoter binding
2.71 1.94e-02 GO:0003779 actin binding
4.58 2.17e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.37 4.04e-02 GO:0046872 metal ion binding