Motif ID: AAGGUGC

Z-value: 0.717


Mature miRNA associated with seed AAGGUGC:

NamemiRBase Accession
hsa-miR-18a MIMAT0000072
hsa-miR-18b MIMAT0001412
hsa-miR-4735-3p MIMAT0019861



Activity profile for motif AAGGUGC.

activity profile for motif AAGGUGC


Sorted Z-values histogram for motif AAGGUGC

Sorted Z-values for motif AAGGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGUGC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_167298280 2.396 NM_001198783
 POU2F1
POU class 2 homeobox 1
chr6_+_11538486 2.262 NM_001100829
 TMEM170B
transmembrane protein 170B
chr15_-_60919642 2.193 NM_002943
NM_134260
 RORA

RAR-related orphan receptor A

chr3_+_151985828 2.043 NM_021038
NM_207292
 MBNL1

muscleblind-like (Drosophila)

chr3_+_152017193 1.963 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
 MBNL1




muscleblind-like (Drosophila)




chr15_-_60884615 1.903 NM_134262
 RORA
RAR-related orphan receptor A
chr5_-_59783885 1.790 NM_001165899
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_61521478 1.757 NM_134261
 RORA
RAR-related orphan receptor A
chr15_-_34610928 1.732 NM_005135
 SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr16_+_28996146 1.717 NM_001014989
 LAT
linker for activation of T cells
chr5_-_58882274 1.711 NM_006203
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr16_+_28996369 1.667 NM_001014987
NM_001014988
NM_014387
 LAT


linker for activation of T cells


chrX_-_19817907 1.615 NM_001024666
 SH3KBP1
SH3-domain kinase binding protein 1
chr14_-_95599794 1.571 NM_001195573
 DICER1
dicer 1, ribonuclease type III
chr15_-_34629044 1.434 NM_001042497
NM_133647
 SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chrX_-_19688991 1.432 NM_001184960
 SH3KBP1
SH3-domain kinase binding protein 1
chr21_-_36421586 1.390 NM_001754
 RUNX1
runt-related transcription factor 1
chr3_-_185542807 1.360 NM_001007225
NM_006548
 IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_+_36621751 1.353 NM_018067
 MAP7D1
MAP7 domain containing 1
chr5_-_58295758 1.329 NM_001197223
 PDE4D
phosphodiesterase 4D, cAMP-specific

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
Enrichment   P-value GO Accession GO Term
103.96 3.67e-02 GO:0035196 production of miRNAs involved in gene silencing by miRNA
96.54 4.28e-02 GO:0031050 dsRNA fragmentation
96.54 4.28e-02 GO:0070918 production of small RNA involved in gene silencing by RNA
52.00 5.51e-03 GO:0031047 gene silencing by RNA
32.21 2.34e-02 GO:0016458 gene silencing
9.44 6.12e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
8.45 2.33e-03 GO:0045893 positive regulation of transcription, DNA-dependent
7.88 3.68e-03 GO:0051254 positive regulation of RNA metabolic process
7.80 3.93e-03 GO:0010628 positive regulation of gene expression
7.08 7.42e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
6.95 4.49e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
6.95 8.31e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
6.75 1.01e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
6.29 1.57e-02 GO:0031328 positive regulation of cellular biosynthetic process
6.19 1.75e-02 GO:0009891 positive regulation of biosynthetic process
5.37 4.28e-02 GO:0009892 negative regulation of metabolic process
3.96 4.23e-02 GO:0016070 RNA metabolic process
3.57 5.51e-03 GO:0010468 regulation of gene expression
3.55 1.57e-02 GO:0048519 negative regulation of biological process
3.54 4.11e-02 GO:0048523 negative regulation of cellular process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
3.09 8.19e-04 GO:0003676 nucleic acid binding