Motif ID: AAUCUCU

Z-value: 0.905


Mature miRNA associated with seed AAUCUCU:

NamemiRBase Accession
hsa-miR-216b MIMAT0004959



Activity profile for motif AAUCUCU.

activity profile for motif AAUCUCU


Sorted Z-values histogram for motif AAUCUCU

Sorted Z-values for motif AAUCUCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_35441501 2.267 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr12_+_111471827 2.110 NM_015267
CUX2
cut-like homeobox 2
chr11_-_35441099 1.991 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr18_-_24442534 1.791 NM_004028
AQP4
aquaporin 4
chr18_-_24445652 1.749 NM_001650
AQP4
aquaporin 4
chr11_-_133402227 1.738 NM_001012393
OPCML
opioid binding protein/cell adhesion molecule-like
chr2_-_229046313 1.673 NM_001142644
NM_030623
SPHKAP

SPHK1 interactor, AKAP domain containing

chr5_-_148442606 1.452 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr11_-_132812870 1.411 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr2_-_102003923 1.334 NM_153836
CREG2
cellular repressor of E1A-stimulated genes 2
chrX_+_37545008 1.322 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr16_-_10276610 1.309 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr3_+_85775631 1.306 NM_153184
CADM2
cell adhesion molecule 2
chr16_-_10276115 1.264 NM_001134407
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr19_+_54466289 1.262 NM_031895
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr16_+_8768403 1.244 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr8_-_133459508 1.244 NM_001204824
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr16_+_8814567 1.212 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr11_+_124789145 1.161 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr16_+_8806825 1.112 NM_000663
ABAT
4-aminobutyrate aminotransferase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
118.56 1.64e-02 GO:0048169 regulation of long-term neuronal synaptic plasticity
80.85 3.60e-02 GO:0014073 response to tropane
80.85 3.60e-02 GO:0042220 response to cocaine
71.16 4.66e-02 GO:0007215 glutamate signaling pathway
71.16 4.66e-02 GO:0048168 regulation of neuronal synaptic plasticity
29.68 1.67e-02 GO:0021537 telencephalon development
13.42 3.69e-04 GO:0007268 synaptic transmission
12.40 3.13e-02 GO:0007610 behavior
11.96 7.20e-04 GO:0019226 transmission of nerve impulse
11.96 7.20e-04 GO:0035637 multicellular organismal signaling
7.83 8.09e-03 GO:0007267 cell-cell signaling
5.91 3.85e-02 GO:0007154 cell communication
5.07 2.64e-02 GO:0050877 neurological system process
4.75 4.01e-02 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
104.62 7.62e-03 GO:0043198 dendritic shaft
55.60 9.06e-04 GO:0043197 dendritic spine
53.38 1.03e-03 GO:0044309 neuron spine
48.10 3.69e-02 GO:0042734 presynaptic membrane
18.96 2.15e-03 GO:0030425 dendrite
9.34 3.31e-02 GO:0043005 neuron projection
3.54 3.46e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
14.31 3.25e-02 GO:0022832 voltage-gated channel activity
5.45 4.68e-02 GO:0022891 substrate-specific transmembrane transporter activity