Motif ID: AGCUUAU

Z-value: 1.195


Mature miRNA associated with seed AGCUUAU:

NamemiRBase Accession
hsa-miR-21 MIMAT0000076
hsa-miR-590-5p MIMAT0003258



Activity profile for motif AGCUUAU.

activity profile for motif AGCUUAU


Sorted Z-values histogram for motif AGCUUAU

Sorted Z-values for motif AGCUUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUUAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_33196801 5.505 NM_000362
 TIMP3
TIMP metallopeptidase inhibitor 3
chr16_-_4292052 2.973 NM_001098814
 SRL
sarcalumenin
chr13_-_110959441 2.844 NM_001845
 COL4A1
collagen, type IV, alpha 1
chr7_-_139876718 2.805 NM_030647
 JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr9_-_14398981 2.753 NM_001190738
 NFIB
nuclear factor I/B
chr2_-_19558371 2.658 NM_145260
 OSR1
odd-skipped related 1 (Drosophila)
chr9_-_14314036 2.655 NM_001190737
NM_005596
 NFIB

nuclear factor I/B

chr8_-_9008138 2.383 NM_024607
 PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr8_-_10587942 2.372 NM_031439
 SOX7
SRY (sex determining region Y)-box 7
chr2_-_218808705 2.204 NM_022648
 TNS1
tensin 1
chr11_+_101980736 2.175 NM_001130145
NM_001195044
NM_006106
 YAP1


Yes-associated protein 1


chr17_+_59477169 2.055 NM_005994
 TBX2
T-box 2
chr1_-_214724974 1.965 NM_005401
 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr8_-_9009050 1.956 NM_001201329
 PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr4_+_124317884 1.948 NM_199327
 SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr3_+_151985828 1.929 NM_021038
NM_207292
 MBNL1

muscleblind-like (Drosophila)

chr4_+_124320664 1.918 NM_005841
 SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr21_-_39870303 1.897 NM_001136155
NM_182918
 ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr5_-_38595506 1.765 NM_002310
 LIFR
leukemia inhibitory factor receptor alpha
chr3_+_152017193 1.682 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
 MBNL1




muscleblind-like (Drosophila)





Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 51 entries
Enrichment   P-value GO Accession GO Term
129.92 4.28e-02 GO:0051387 negative regulation of nerve growth factor receptor signaling pathway
129.92 4.28e-02 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway
30.95 3.70e-03 GO:0030509 BMP signaling pathway
15.48 7.76e-03 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
12.91 1.87e-02 GO:0042692 muscle cell differentiation
10.61 9.13e-03 GO:0007517 muscle organ development
10.05 4.95e-04 GO:0061061 muscle structure development
9.15 4.61e-03 GO:0001568 blood vessel development
8.50 7.42e-03 GO:0001944 vasculature development
7.64 3.80e-03 GO:0048598 embryonic morphogenesis
6.80 2.50e-03 GO:0072358 cardiovascular system development
6.80 2.50e-03 GO:0072359 circulatory system development
6.61 2.54e-04 GO:0009887 organ morphogenesis
6.19 1.73e-02 GO:0048646 anatomical structure formation involved in morphogenesis
5.55 4.25e-03 GO:0007167 enzyme linked receptor protein signaling pathway
5.35 5.86e-03 GO:0010628 positive regulation of gene expression
5.29 2.25e-03 GO:2000026 regulation of multicellular organismal development
5.22 7.33e-03 GO:0009790 embryo development
5.22 2.06e-02 GO:0045893 positive regulation of transcription, DNA-dependent
5.03 1.28e-03 GO:0009888 tissue development

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
26.35 1.57e-02 GO:0032587 ruffle membrane

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
162.39 4.61e-03 GO:0004897 ciliary neurotrophic factor receptor activity
92.80 1.60e-02 GO:0034713 type I transforming growth factor beta receptor binding
64.97 3.41e-02 GO:0008191 metalloendopeptidase inhibitor activity
64.97 3.41e-02 GO:0048551 metalloenzyme inhibitor activity
59.06 4.17e-02 GO:0010576 metalloenzyme regulator activity
57.33 1.49e-03 GO:0005024 transforming growth factor beta receptor activity
51.30 2.11e-03 GO:0004675 transmembrane receptor protein serine/threonine kinase activity
28.89 8.76e-04 GO:0046332 SMAD binding
12.16 2.64e-02 GO:0019838 growth factor binding
8.06 3.07e-02 GO:0000975 regulatory region DNA binding
8.06 3.07e-02 GO:0001067 regulatory region nucleic acid binding
8.06 3.07e-02 GO:0044212 transcription regulatory region DNA binding
6.51 2.43e-02 GO:0016564 transcription repressor activity
5.07 1.68e-03 GO:0043565 sequence-specific DNA binding
4.21 1.41e-03 GO:0001071 nucleic acid binding transcription factor activity
4.21 1.41e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
3.77 9.28e-03 GO:0030528 transcription regulator activity
2.40 4.27e-02 GO:0003677 DNA binding